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Autosomal dominant polycystic kidney disease
Autosomal dominant polycystic kidney disease
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Subtype of:
Polycystic kidney disease
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
autosomal dominant polycystic kidney disease
730
MONDO:0004691
MONDO_0004691
ALG5
Unknown
—
ClinGen
N-Glycan biosynthesis
Metabolic pathways
Synthesis of dolichyl-phosphate-glucose
ALG8
Unknown
—
ClinGen
N-Glycan biosynthesis
Metabolic pathways
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Defective ALG8 causes ALG8-CDG (CDG-1h)
+1 more
ALG9
Unknown
31395617
Open Targets
N-Glycan biosynthesis
Various types of N-glycan biosynthesis
Metabolic pathways
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Defective ALG9 causes ALG9-CDG (CDG-1l)
+2 more
NEK8
Unknown
—
ClinGen
—
All
8
Causal
5
Unknown
4
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
3
Open Targets
1
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Diseases that share the most curated genes with Autosomal dominant polycystic kidney disease.
5
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Liver cyst
2 shared genes
PKD1, PKD2
Related via 2 shared genes including PKD1, PKD2.
Anhydramnios
3 shared genes
DNAJB11, PKD1, PKD2
Related via 3 shared genes including DNAJB11, PKD1, PKD2.
Polycystic kidney disease
8 shared genes
ALG8, ALG9, DNAJB11, PKD1, PKD2, IFT140, ALG5, NEK8
Related via 8 shared genes including ALG8, ALG9, DNAJB11.
Gillessen-kaesbach-nishimura syndrome
1 shared gene
ALG9
Related via 1 shared gene including ALG9.
End stage renal failure
1 shared gene
DNAJB11
Related via 1 shared gene including DNAJB11.
1
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