Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
ATRIAL FIBRILLATION	C0004238 EFO_0000275 MESH:D001281	FBXO32	Unknown	29892015 30061737 34594039 35872910 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	FoxO signaling pathway Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FERD3L	Unknown	27790247	GWAS catalog	—
		FERMT2	Unknown	40645996	GWAS catalog	Cell-extracellular matrix interactions
		FES	Unknown	40645996	GWAS catalog	Axon guidance Signaling by SCF-KIT Sema3A PAK dependent Axon repulsion +1 more
		FGD5	Unknown	40050429 40645996	GWAS catalog	—
		FGF13	Unknown	36653681	GWAS catalog	Phase 0 - rapid depolarisation
		FGF14	Unknown	40050429 40645996	GWAS catalog	Spinocerebellar ataxia Phase 0 - rapid depolarisation
		FGF5	Unknown	29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +40 more
		FGFR2	Unknown	40050429 40645996	GWAS catalog	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		FGFR3	Unknown	40645996	GWAS catalog	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +27 more
		FGFRL1	Unknown	40645996	GWAS catalog	FGFRL1 modulation of FGFR1 signaling
		FIGN	Unknown	40645996	GWAS catalog	—
		FILIP1	Unknown	35872910 36653681 40050429 40645996	GWAS catalog	—
		FILIP1L	Unknown	40645996	GWAS catalog	—
		FNDC3B	Unknown	40050429 40645996	GWAS catalog	—
		FOLH1	Unknown	40645996	GWAS catalog	Alanine, aspartate and glutamate metabolism Metabolic pathways Vitamin digestion and absorption +2 more
		FOXK1	Unknown	40050429 40645996	GWAS catalog	Polycomb repressive complex UCH proteinases
		FOXO1	Unknown	40645996	GWAS catalog	FoxO signaling pathway AMPK signaling pathway Longevity regulating pathway +23 more
		FPGT-TNNI3K	Unknown	40645996	GWAS catalog	—
		FRMD4A	Unknown	40645996	GWAS catalog	—
		FRMD4B	Unknown	29892015 30061737 34594039 35872910 36653681 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	—
		FRS2	Unknown	39024449	GWAS catalog	Thermogenesis Neurotrophin signaling pathway Proteoglycans in cancer +25 more
		FTCDNL1	Unknown	40050429	GWAS catalog	—
		FTO	Unknown	27790247 39024449 40050429 40645996 41022758	GWAS catalog	Reversal of alkylation damage by DNA dioxygenases
		FXR2	Unknown	39024449	GWAS catalog	—
		FXYD4	Unknown	40050429	GWAS catalog	Aldosterone-regulated sodium reabsorption Ion homeostasis Ion transport by P-type ATPases
		GALNT12	Unknown	40050429 40645996	GWAS catalog	Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways +2 more
		GATA4	Unknown	29892015 30061737 35872910 39537608	CTD, Disgenet, GWAS catalog	cGMP-PKG signaling pathway Cellular senescence Tight junction +5 more
		GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
		GATAD2A	Unknown	40645996	GWAS catalog	ATP-dependent chromatin remodeling HDACs deacetylate histones Regulation of TP53 Activity through Acetylation +2 more
		GBF1	Unknown	39537608	GWAS catalog	Endocytosis trans-Golgi Network Vesicle Budding VxPx cargo-targeting to cilium +2 more
		GCKR	Unknown	27790247	GWAS catalog	Regulation of Glucokinase by Glucokinase Regulatory Protein Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
		GCOM1	Unknown	29892015 30061737 40645996	CTD, GWAS catalog	—
		GFPT1	Unknown	40050429	GWAS catalog	Alanine, aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways +6 more
		GHR	Unknown	40050429 40645996	GWAS catalog	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Hormone signaling +5 more
		GJA1	Unknown	40050429	GWAS catalog	Gap junction Arrhythmogenic right ventricular cardiomyopathy Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane +4 more
		GJA5	Unknown	29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429	CTD, Disgenet, GWAS catalog	Gap junction assembly
		GJA8	Unknown	29892015 30061737 34594039 35872910 39024449 39537608 40050429	GWAS catalog	Gap junction assembly
		GJB7	Unknown	40645996	GWAS catalog	Gap junction assembly
		GJD2	Unknown	40645996	GWAS catalog	Gap junction Electric Transmission Across Gap Junctions Gap junction assembly
		GMCL1	Unknown	29892015 30061737 35872910 36653681 39537608 40050429 40645996	GWAS catalog	—
		GNA12	Unknown	40050429 40645996	GWAS catalog	MAPK signaling pathway cGMP-PKG signaling pathway Sphingolipid signaling pathway +11 more
		GNB4	Unknown	29892015 30061737 35872910	CTD, Disgenet, GWAS catalog	Ras signaling pathway Chemokine signaling pathway Hormone signaling +43 more
		GNPNAT1	Unknown	40645996	GWAS catalog	Amino sugar and nucleotide sugar metabolism Metabolic pathways Biosynthesis of nucleotide sugars +1 more
		GON4L	Unknown	40645996	GWAS catalog	—
		GOPC	Unknown	29892015	CTD, Disgenet	RHO GTPases regulate CFTR trafficking
		GORAB	Unknown	22544366 28416818 28416822 28460022 29892015 30061737 34594039 35872910 36653681 38574792 39024449 39537608 40050429 40645996	GWAS catalog	p53 signaling pathway
		GOSR2	Unknown	29892015 40050429 40645996	CTD, Disgenet, GWAS catalog	SNARE interactions in vesicular transport COPII-mediated vesicle transport XBP1(S) activates chaperone genes +3 more
		GPA33	Unknown	40645996	GWAS catalog	—
		GPATCH2	Unknown	40050429 40645996	GWAS catalog	—
ATRIAL FIBRILLATION, FAMILIAL 1	C1843687	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL 1	C1843687	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 10	C3151464	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 10	C3151464	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 11	C3279693	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 12	C3279695	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 12	C3279695	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 13	C3809311	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 13	C3809311	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 14	C3809312	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 14	C3809312	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 15	C4014269	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 15	C4014269	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 2	C1837812	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 2	C1837812	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 3	C1837014	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 3	C1837014	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 4	C1862394	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 4	C1862394	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 5	C1969099	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 5	C1969099	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 6	C2677294	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 6	C2677294	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 7	C2677106	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 7	C2677106	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 8	C2751607	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 8	C2751607	GJA5	Unknown	—	Disgenet	Gap junction assembly
ATRIAL FIBRILLATION, FAMILIAL, 9	C3151431	GATA5	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
ATRIAL FIBRILLATION, FAMILIAL, 9	C3151431	GJA5	Unknown	—	Disgenet	Gap junction assembly
FAMILIAL ATRIAL FIBRILLATION	MONDO:0018054	GATA4	Unknown	21708142 21874226 22552926	GWAS catalog	cGMP-PKG signaling pathway Cellular senescence Tight junction +5 more
		GATA5	Unknown	22483626 23175127 23295592	GWAS catalog	Factors involved in megakaryocyte development and platelet production
		GJA5	Unknown	20650941	Disgenet	Gap junction assembly

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Atrial fibrillation

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