Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
ATRIAL FIBRILLATION	EFO_0000275 C0004238 MESH:D001281	PLCG1	Unknown	27790247	GWAS catalog	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +70 more
		PLCL1	Unknown	40050429 40645996	GWAS catalog	GABAergic synapse
		PLCXD2	Unknown	30061737 35872910 36653681 39024449 39537608 40645996	GWAS catalog	—
		PLEC	Unknown	40050429	GWAS catalog	Cytoskeleton in muscle cells Assembly of collagen fibrils and other multimeric structures Caspase-mediated cleavage of cytoskeletal proteins +1 more
		PLEKHG4B	Unknown	40050429 40645996	GWAS catalog	—
		PLEKHJ1	Unknown	40050429 40645996	GWAS catalog	—
		PLN	Unknown	30061737	CTD, Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +6 more
		PLPP3	Unknown	40645996	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism +7 more
		PMVK	Unknown	28416818 29892015 30061737 34594039 35872910 36653681 39537608	GWAS catalog	Terpenoid backbone biosynthesis Metabolic pathways Peroxisome +2 more
		POC5	Unknown	27790247	GWAS catalog	—
		POLD1	Unknown	34594039 40050429 40645996	GWAS catalog	DNA replication Base excision repair Nucleotide excision repair +19 more
		POLD3	Unknown	40645996	GWAS catalog	DNA replication Base excision repair Nucleotide excision repair +19 more
		POLK	Unknown	27790247	GWAS catalog	Fanconi anemia pathway Epstein-Barr virus infection Pathways in cancer +21 more
		POLR1F	Unknown	27790247	GWAS catalog	RNA polymerase
		POLR2A	Unknown	29892015 36653681 40050429 40645996	GWAS catalog	RNA polymerase Nucleotide excision repair Huntington disease +25 more
		POLR2M	Unknown	40050429	GWAS catalog	RNA polymerase Nucleotide excision repair
		POM121C	Unknown	40050429	GWAS catalog	Nucleocytoplasmic transport Amyotrophic lateral sclerosis
		POPDC1	Unknown	40050429	GWAS catalog	—
		POPDC3	Unknown	40645996	GWAS catalog	cAMP signaling pathway Adrenergic signaling in cardiomyocytes
		PPFIA4	Unknown	28416822 29892015 30061737 28460022 34594039 35872910 36653681 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle +3 more
		PPFIBP1	Unknown	40645996	GWAS catalog	Receptor-type tyrosine-protein phosphatases
		PPM1G	Unknown	27790247	GWAS catalog	—
		PPP1R3A	Unknown	40050429 40645996	GWAS catalog	Insulin signaling pathway Insulin resistance
		PPP2R3A	Unknown	29892015 30061737 35872910 36653681 39537608	CTD, Disgenet, GWAS catalog	mRNA surveillance pathway Sphingolipid signaling pathway PI3K-Akt signaling pathway +5 more
		PPP5C	Unknown	40645996	GWAS catalog	MAPK signaling pathway Negative regulation of MAPK pathway Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks +1 more
		PRDM11	Unknown	40050429	GWAS catalog	—
		PRDM5	Unknown	40645996	GWAS catalog	—
		PRDM6	Unknown	34594039 40645996	GWAS catalog	Lysine degradation Metabolic pathways
		PRDM8	Unknown	29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429 40645996	GWAS catalog	—
		PRKCH	Unknown	40645996	GWAS catalog	Vascular smooth muscle contraction Inflammatory mediator regulation of TRP channels Effects of PIP2 hydrolysis
		PRKD1	Unknown	40645996	GWAS catalog	Rap1 signaling pathway Aldosterone synthesis and secretion Chemical carcinogenesis - reactive oxygen species +1 more
		PRKG2	Unknown	40645996	GWAS catalog	cGMP-PKG signaling pathway Hormone signaling Gap junction +10 more
		PRRX1	Unknown	22544366 28416818 28416822 28460022 29892015 30061737 34594039 35872910 36653681 38574792 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	—
		PRXL2A	Unknown	40645996	GWAS catalog	—
		PSMB7	Unknown	29892015 40050429	CTD, Disgenet, GWAS catalog	Proteasome Alzheimer disease Parkinson disease +57 more
		PSMD2	Unknown	40050429 40645996	GWAS catalog	Proteasome Alzheimer disease Parkinson disease +58 more
		PTCH1	Unknown	40050429	GWAS catalog	cAMP signaling pathway Hedgehog signaling pathway Axon guidance +7 more
		PTCHD1	Unknown	36653681	GWAS catalog	—
		PTGES3	Unknown	29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429	GWAS catalog	Arachidonic acid metabolism Metabolic pathways Chemical carcinogenesis - receptor activation +7 more
		PTK2	Unknown	29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	Endocrine resistance ErbB signaling pathway Chemokine signaling pathway +37 more
		PTPN11	Unknown	40050429	GWAS catalog	Ras signaling pathway Phospholipase D signaling pathway Efferocytosis +56 more
		PTPRD	Unknown	40050429 40645996	GWAS catalog	Cell adhesion molecules Receptor-type tyrosine-protein phosphatases Synaptic adhesion-like molecules
		PTPRJ	Unknown	40645996	GWAS catalog	Adherens junction Chemical carcinogenesis - reactive oxygen species Phosphorylation of CD3 and TCR zeta chains +2 more
		PTPRR	Unknown	40645996	GWAS catalog	MAPK signaling pathway
		PTPRS	Unknown	40645996	GWAS catalog	Cell adhesion molecules Receptor-type tyrosine-protein phosphatases Synaptic adhesion-like molecules
		PUS10	Unknown	40050429	GWAS catalog	—
		PXN	Unknown	40645996 41022758	GWAS catalog	Chemokine signaling pathway VEGF signaling pathway Focal adhesion +16 more
		QSER1	Unknown	40645996	GWAS catalog	—
		RAB17	Unknown	40645996	GWAS catalog	Efferocytosis RAB geranylgeranylation
		RAB1A	Unknown	36653681	GWAS catalog	Autophagy - animal Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases +8 more

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Atrial fibrillation

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