Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
ATRIAL FIBRILLATION	EFO_0000275 C0004238 MESH:D001281	A3GALT2	Unknown	40645996	GWAS catalog	Glycosphingolipid biosynthesis - globo and isoglobo series Metabolic pathways
		ABCA12	Unknown	27790247	GWAS catalog	ABC transporters ABC transporters in lipid homeostasis Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B
		ABCC10	Unknown	40645996	GWAS catalog	ABC transporters ABC-family proteins mediated transport
		ABHD10	Unknown	39537608	GWAS catalog	Glucuronidation
		ABHD17C	Unknown	30061737 39537608	GWAS catalog	—
		ABHD5	Unknown	40645996	GWAS catalog	Regulation of lipolysis in adipocytes
		ABHD8	Unknown	40645996	GWAS catalog	—
		ABLIM1	Unknown	40050429 40645996	GWAS catalog	Axon guidance
		ABO	Unknown	40645996	GWAS catalog	Glycosphingolipid biosynthesis - lacto and neolacto series Glycosphingolipid biosynthesis - globo and isoglobo series Metabolic pathways +1 more
		ACAD10	Unknown	34594039	GWAS catalog	Mitochondrial Fatty Acid Beta-Oxidation
		ACE	Unknown	15331425	CTD, Disgenet	Renin-angiotensin system Renin secretion Chagas disease +4 more
		ACTRT2	Unknown	40645996	GWAS catalog	—
		ACVR2A	Unknown	40645996	GWAS catalog	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +3 more
		ADAM15	Unknown	39537608	GWAS catalog	Degradation of the extracellular matrix Invadopodia formation
		ADGRB1	Unknown	40645996	GWAS catalog	p53 signaling pathway Efferocytosis
		ADGRD2	Unknown	29892015	GWAS catalog	—
		ADGRV1	Unknown	40645996	GWAS catalog	—
		ADH1B	Unknown	40645996	GWAS catalog	Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism +7 more
		ADPRHL1	Unknown	40050429 40645996	GWAS catalog	—
		ADRA1A	Unknown	40050429	GWAS catalog	Calcium signaling pathway cGMP-PKG signaling pathway Neuroactive ligand-receptor interaction +8 more
		AFF3	Unknown	40050429	GWAS catalog	—
		AGBL4	Unknown	29892015 30061737 35872910 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	—
		AGPAT1	Unknown	40050429	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways +4 more
		AGRN	Unknown	40645996	GWAS catalog	ECM-receptor interaction Cytoskeleton in muscle cells A tetrasaccharide linker sequence is required for GAG synthesis +9 more
		AGT	Unknown	40645996	Disgenet, GWAS catalog	Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +18 more
		AGXT2	Unknown	—	Disgenet	Alanine, aspartate and glutamate metabolism Glycine, serine and threonine metabolism Cysteine and methionine metabolism +4 more
		AK9	Unknown	40645996	GWAS catalog	Purine metabolism Pyrimidine metabolism Metabolic pathways +3 more
		AKAP6	Unknown	29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	—
		AKIRIN2	Unknown	40050429	GWAS catalog	—
		ALDH1A2	Unknown	27790247 40050429	GWAS catalog	Retinol metabolism Metabolic pathways RA biosynthesis pathway
		ALDH2	Unknown	34594039 40050429	GWAS catalog	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid degradation +14 more
		ALPK1	Unknown	30061737	GWAS catalog	Alpha-protein kinase 1 signaling pathway
		AMPD3	Unknown	40645996	GWAS catalog	Purine metabolism Metabolic pathways Nucleotide metabolism +3 more
		AMZ1	Unknown	40050429 40645996	GWAS catalog	—
		ANAPC10	Unknown	40645996	GWAS catalog	Cell cycle Oocyte meiosis Ubiquitin mediated proteolysis +18 more
		ANAPC4	Unknown	40645996	GWAS catalog	Cell cycle Oocyte meiosis Ubiquitin mediated proteolysis +18 more
		ANGPT1	Unknown	40645996	GWAS catalog	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +5 more
		ANK2	Unknown	—	Disgenet	Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins +1 more
		ANK3	Unknown	40645996	GWAS catalog	Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins +1 more
		ANKRD17	Unknown	40645996	GWAS catalog	—
		ANKRD26	Unknown	27790247	GWAS catalog	—
		ANKRD31	Unknown	27790247	GWAS catalog	—
		ANO5	Unknown	40050429 40645996	GWAS catalog	Efferocytosis Stimuli-sensing channels
		ANO8	Unknown	40645996	GWAS catalog	Stimuli-sensing channels Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
		ANXA4	Unknown	28416818	GWAS catalog	—
		AOC1	Unknown	40645996	GWAS catalog	Arginine and proline metabolism Histidine metabolism Tryptophan metabolism +3 more
		AOPEP	Unknown	22544366 29892015 30061737 28416818 34594039 35872910 36653681 39024449 39537608 40050429 40645996	CTD, GWAS catalog	Metabolism of Angiotensinogen to Angiotensins
		AP3D1	Unknown	39024449	GWAS catalog	Lysosome
		APOB	Unknown	27790247	GWAS catalog	Fat digestion and absorption Vitamin digestion and absorption Cholesterol metabolism +20 more
		APOBEC3A	Unknown	40645996	GWAS catalog	Viral life cycle - HIV-1 Human immunodeficiency virus 1 infection mRNA Editing: C to U Conversion +1 more

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Atrial fibrillation

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