Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
ANXIETY DISORDERS	C0003469 MESH:D001008	CRH	Unknown	11440811 11875628 12424556 12438692 14575894 16495007 17293045 21268831 22231481 7816204 8736133	CTD, Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +6 more
		CRHR1	Unknown	22231481 9299637	CTD, Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +5 more
		CRHR2	Unknown	10742108	CTD, Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +5 more
		CRP	Unknown	20194079	CTD, Disgenet	Classical antibody-mediated complement activation
		CTNND2	Unknown	—	Disgenet	Wnt signaling pathway
		DISC1	Unknown	29643356	CTD, Disgenet	—
		DIXDC1	Unknown	27752079	CTD, Disgenet	—
		DNMT1	Unknown	23791455	CTD, Disgenet	Cysteine and methionine metabolism Metabolic pathways MicroRNAs in cancer +2 more
		EOMES	Unknown	26415720	CTD, Disgenet	—
		FMR1	Unknown	28616095	CTD, Disgenet	—
		FNTB	Unknown	—	Disgenet	Terpenoid backbone biosynthesis Inactivation, recovery and regulation of the phototransduction cascade
		FOS	Unknown	16488545	CTD, Disgenet	Endocrine resistance MAPK signaling pathway cAMP signaling pathway +51 more
		GABRA2	Unknown	18313124	CTD, Disgenet	Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling GABAergic synapse +4 more
		GAD1	Unknown	—	Disgenet	Alanine, aspartate and glutamate metabolism beta-Alanine metabolism Taurine and hypotaurine metabolism +6 more
		GDNF	Unknown	—	Disgenet	MAPK signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway +2 more
		GLO1	Unknown	22113448	CTD, Disgenet	Pyruvate metabolism Metabolic pathways Pyruvate metabolism
		GNB1	Unknown	22113448	CTD, Disgenet	Ras signaling pathway Chemokine signaling pathway Hormone signaling +47 more
		GRM8	Unknown	17434465	CTD, Disgenet	Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Glutamatergic synapse +2 more
		HTR1A	Unknown	—	Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Serotonergic synapse +3 more
		HTR7	Unknown	21859099	CTD, Disgenet	Ras signaling pathway Calcium signaling pathway Neuroactive ligand-receptor interaction +4 more
		IFNA2	Unknown	12297606	CTD	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway Necroptosis +26 more
		MAGI2	Unknown	25653350	CTD, Disgenet	Rap1 signaling pathway PI3K-Akt signaling pathway
		MANEA	Unknown	—	Disgenet	N-glycan trimming and elongation in the cis-Golgi
		MAPT	Unknown	29860433	CTD, Disgenet	MAPK signaling pathway Alzheimer disease Parkinson disease +2 more
		MDK	Unknown	19217924	CTD, Disgenet	NOTCH2 Activation and Transmission of Signal to the Nucleus
		MECP2	Unknown	22231481	CTD, Disgenet	Transcriptional Regulation by MECP2 Loss of MECP2 binding ability to 5hmC-DNA Loss of MECP2 binding ability to 5mC-DNA +2 more
		MIF	Unknown	20177408	CTD, Disgenet	Tyrosine metabolism Phenylalanine metabolism Metabolic pathways +3 more
		NPS	Unknown	19339610 21466221	CTD, Disgenet	Neuroactive ligand-receptor interaction Peptide ligand-binding receptors G alpha (q) signalling events +2 more
		NPY	Unknown	11440811	CTD, Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Adipocytokine signaling pathway +5 more
		NPY1R	Unknown	11440811	CTD, Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Regulation of lipolysis in adipocytes +2 more
		OXT	Unknown	19228979	CTD, Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +3 more
		PAM	Unknown	19815072	CTD, Disgenet	—
		RAI1	Unknown	18285828	CTD, Disgenet	—
		SAT1	Unknown	—	Disgenet	Arginine and proline metabolism Metabolic pathways Ferroptosis +1 more
		SERPINA1	Unknown	17659342	CTD, Disgenet	Complement and coagulation cascades Platelet degranulation COPII-mediated vesicle transport +4 more
		SHANK1	Unknown	18272690	CTD, Disgenet	Glutamatergic synapse Neurexins and neuroligins
		SLC6A3	Unknown	19120712	CTD, Disgenet	Synaptic vesicle cycle Dopaminergic synapse Parkinson disease +7 more
		SMS	Unknown	—	Disgenet	Cysteine and methionine metabolism Arginine and proline metabolism Glutathione metabolism +2 more
		TAFA2	Unknown	29339520	CTD, Disgenet	—
		TG	Unknown	30373627	CTD, Disgenet	Thyroid hormone synthesis Autoimmune thyroid disease
		TNF	Unknown	20194079	CTD, Disgenet	Antifolate resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +72 more
		TPH2	Unknown	—	Disgenet	Tryptophan metabolism Folate biosynthesis Metabolic pathways +2 more
		UCN	Unknown	16488545	CTD, Disgenet	Neuroactive ligand-receptor interaction Hormone signaling Class B/2 (Secretin family receptors) +1 more
ANXIETY, SEPARATION	MESH:D001010	DRD4	Unknown	20731709	CTD	Neuroactive ligand-receptor interaction Hormone signaling Dopaminergic synapse +2 more

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Anxiety disorder

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