Subtype of: Lung cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
adenosquamous lung carcinoma	MONDO_0004973	ABL1	Unknown	16140923 28481359 29681454 33137577	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ACSL3	Unknown	29681454	Open Targets	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways +8 more
		ACVR1B	Unknown	33137577	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +1 more
		AFDN	Unknown	29681454	Open Targets	Ras signaling pathway Rap1 signaling pathway cAMP signaling pathway +4 more
		AKAP9	Unknown	29681454 33200540	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +7 more
		ALK	Unknown	16140923 17625570 18242762 18414414 18594010 19147828 19383809 19472407 19667264 20183914 20624322 20813423 21168933 21225871 22142829 22425930 22505007 22736493 22768234 22913857 22948846 23341890 23661334 23951022 24481316 24729716 24736079 26925973 27009842 29308976 29681454 33137577	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		AMER1	Unknown	26215952 28481359 29681454 33137577 33200540	Open Targets	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane +8 more
		APC	Unknown	26124082 28481359 29681454 31534501	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AR	Unknown	28481359 29681454	Open Targets	Oocyte meiosis Pathways in cancer Chemical carcinogenesis - receptor activation +7 more
		ARHGAP5	Unknown	29681454	Open Targets	Focal adhesion Leukocyte transendothelial migration Rho GTPase cycle
		ARHGEF10	Unknown	29681454	Open Targets	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ARID1A	Unknown	22009941 23856246 26215952 28103823 28481359 29535832 29681454 33384420	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ASXL2	Unknown	28481359	Open Targets	Polycomb repressive complex UCH proteinases
		ATIC	Unknown	18242762	Open Targets	Purine metabolism One carbon pool by folate Metabolic pathways +2 more
		ATM	Unknown	16140923 26317919 28481359 29535832 29658848 29681454 33200540	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATP2B3	Unknown	29681454	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +9 more
		AXIN2	Unknown	29681454	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		BCL11A	Unknown	29681454	Open Targets	—
		BIRC6	Unknown	26215952 29681454	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BLM	Unknown	28892047 29681454	Open Targets	Homologous recombination Fanconi anemia pathway Processive synthesis on the C-strand of the telomere +10 more
		BMPR1A	Unknown	29681454	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling TGF-beta signaling pathway +4 more
		BRAF	Unknown	18636014 20551065 23196793 25969368 26124082 26215952 26317919 26923333 27174587 29035458 29535832 30032818 33115932 33137577 33200540 37546400	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	29681454 33384420	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRD3	Unknown	29681454	Open Targets	—
		BRIP1	Unknown	29681454	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more
		CBLB	Unknown	23856246 29658848	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +5 more
		CBLC	Unknown	29681454	Open Targets	Ubiquitin mediated proteolysis Endocytosis
		CCDC6	Unknown	23150706 27588476 29681454 33200540	Open Targets	Pathways in cancer Thyroid cancer
		CCNE1	Unknown	29681454	Open Targets	Cell cycle Oocyte meiosis p53 signaling pathway +24 more
		CDH1	Unknown	29681454 28481359	Open Targets	Rap1 signaling pathway Apelin signaling pathway Hippo signaling pathway +15 more
		CDKN2A	Unknown	23355336 26317919 28481359 28892047 29681454 30263099 7563154 7591275 7700630 7972006 8521414 8631583 9624535	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CEP43	Unknown	33137577	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes +6 more
		CEP89	Unknown	22510280 33137577	Open Targets	Anchoring of the basal body to the plasma membrane
		CLTC	Unknown	18242762 29681454	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		CNBD1	Unknown	26215952 29681454	Open Targets	—
		CNOT3	Unknown	33137577	Open Targets	RNA degradation Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		COL3A1	Unknown	29681454	Open Targets	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		CREB1	Unknown	33137577	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway Efferocytosis +53 more
		CREBBP	Unknown	28103823 29535832 29681454	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CRNKL1	Unknown	29681454	Open Targets	Spliceosome mRNA Splicing - Major Pathway
		CRTC1	Unknown	29681454 19269006	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CSF1R	Unknown	29681454	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CTCF	Unknown	29681454	Open Targets	—
		CTNNA2	Unknown	29681454	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +6 more
		CTNND1	Unknown	33137577	Open Targets	Rap1 signaling pathway Adherens junction Leukocyte transendothelial migration +3 more
		CTNND2	Unknown	26215952 29681454	Open Targets	Wnt signaling pathway
		CYLD	Unknown	29681454	Open Targets	NF-kappa B signaling pathway Necroptosis Osteoclast differentiation +9 more
		DCAF12L2	Unknown	29681454	Open Targets	—
		DCC	Unknown	29681454	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DDX3X	Unknown	29681454	Open Targets	RIG-I-like receptor signaling pathway Hepatitis B Viral carcinogenesis +1 more

«‹12 3 ›»

Adenosquamous lung carcinoma

Bookmark This Disease