Subtype of: Melanoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
acral lentiginous melanoma	MONDO_0003865	ACSL3	Unknown	26359337	Open Targets	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways +8 more
		ACSL6	Unknown	36219477 28467829	Open Targets	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways +7 more
		ACVR1	Unknown	28467829	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling TGF-beta signaling pathway +2 more
		ACVR1B	Unknown	36219477	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +1 more
		AFF3	Unknown	28467829	Open Targets	—
		AFF4	Unknown	22578220	Open Targets	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events +1 more
		AKAP9	Unknown	22578220 36219477 28467829	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +7 more
		AKT2	Unknown	36219477	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +122 more
		AKT3	Unknown	36219477 26359337	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +119 more
		ALDH2	Unknown	22578220	Open Targets	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid degradation +14 more
		ALK	Unknown	28870692	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		AMER1	Unknown	26359337	Open Targets	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane +8 more
		APC	Unknown	26359337 28870692 36219477	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AR	Unknown	26359337 36219477	Open Targets	Oocyte meiosis Pathways in cancer Chemical carcinogenesis - receptor activation +7 more
		ARHGAP35	Unknown	26359337	Open Targets	Focal adhesion Platelet activation Leukocyte transendothelial migration +4 more
		ARHGAP5	Unknown	22578220	Open Targets	Focal adhesion Leukocyte transendothelial migration Rho GTPase cycle
		ARHGEF10L	Unknown	28467829	Open Targets	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ARHGEF12	Unknown	26359337	Open Targets	Vascular smooth muscle contraction Axon guidance Platelet activation +12 more
		ARID1A	Unknown	22578220 36219477	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID1B	Unknown	22578220	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	26359337 28467829 36219477	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ARNT	Unknown	26359337	Open Targets	HIF-1 signaling pathway Efferocytosis Cushing syndrome +10 more
		ASPM	Unknown	36219477 22578220 26359337	Open Targets	—
		ASXL1	Unknown	26359337	Open Targets	Polycomb repressive complex UCH proteinases
		ATIC	Unknown	26359337	Open Targets	Purine metabolism One carbon pool by folate Metabolic pathways +2 more
		ATM	Unknown	36219477 28467829 28870692 26359337	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATP2B3	Unknown	26359337	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +9 more
		ATR	Unknown	36219477 26359337	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		ATRX	Unknown	26359337 28481359	Open Targets	Cell cycle
		AXIN1	Unknown	22578220	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		BAP1	Unknown	36219477 21874003	Open Targets	Polycomb repressive complex UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
		BARD1	Unknown	28481359	Open Targets	Homologous recombination HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) +11 more
		BCL11A	Unknown	22578220 28467829	Open Targets	—
		BCL11B	Unknown	28467829	Open Targets	Transcriptional misregulation in cancer
		BCL6	Unknown	28481359	Open Targets	FoxO signaling pathway Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation +3 more
		BCL9	Unknown	28467829	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCL9L	Unknown	28467829	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCLAF1	Unknown	22578220 36219477	Open Targets	—
		BCOR	Unknown	26359337 28467829 36219477	Open Targets	Polycomb repressive complex
		BCR	Unknown	26359337 28467829	Open Targets	Pathways in cancer Chronic myeloid leukemia Signaling by cytosolic FGFR1 fusion mutants +2 more
		BIRC3	Unknown	28467829	Open Targets	Platinum drug resistance NF-kappa B signaling pathway Ubiquitin mediated proteolysis +23 more
		BIRC6	Unknown	26359337	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BLM	Unknown	22578220 36219477 26359337	Open Targets	Homologous recombination Fanconi anemia pathway Processive synthesis on the C-strand of the telomere +10 more
		BMP5	Unknown	26359337 28467829	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway
		BRAF	Unknown	23014346 17535228 21326296 36219477 21788131 20544847 25857817 25839886 16773193 28467829 24942556 21356389 23938765 24882974 16098043 16417231 14961576 27771229 28373299 23993026 15191558 22261812 20720566 25767048 16117801 15331929 25363280 23110010 22020039 16899595 25766129 26359337 22437319 25695247 28481359 21499247 24617955	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	36219477 22578220 28467829 28481359 26359337	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	22578220 36219477	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRIP1	Unknown	22578220	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more
		CACNA1D	Unknown	26359337	Open Targets	MAPK signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +35 more
		CAMTA1	Unknown	36219477	Open Targets	—

«‹12 3…7 ›»

Acral lentiginous melanoma

Bookmark This Disease