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GINS1 (GINS complex subunit 1)

Gene

9837

GINS complex subunit 1

GINS1

IMD55, PSF1

20p11.21

The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg ext

Show/Hide all(2)

SNP ID	Visualize variation	Clinical significance	Consequence
rs137901350	C>T	Likely-pathogenic	Coding sequence variant, non coding transcript variant, missense variant
rs376610445	G>A	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, missense variant, non coding transcript variant

Show/Hide all(587)

miRTarBase ID	miRNA	Experiments	Reference
MIRT021144	hsa-miR-186-5p	Sequencing	20371350
MIRT025773	hsa-miR-7-5p	Microarray	19073608
MIRT029528	hsa-miR-26b-5p	Microarray	19088304
MIRT040758	hsa-miR-18a-3p	CLASH	23622248
MIRT083229	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT083230	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT737208	hsa-miR-101-5p	Luciferase reporter assay, Immunohistochemistry (IHC), qRT-PCR	31755218
MIRT1019053	hsa-miR-105	CLIP-seq
MIRT1019054	hsa-miR-1183	CLIP-seq
MIRT1019055	hsa-miR-1207-3p	CLIP-seq
MIRT1019056	hsa-miR-1224-3p	CLIP-seq
MIRT1019057	hsa-miR-1245	CLIP-seq
MIRT1019058	hsa-miR-1245b-5p	CLIP-seq
MIRT1019059	hsa-miR-1252	CLIP-seq
MIRT1019060	hsa-miR-1260	CLIP-seq
MIRT1019061	hsa-miR-1260b	CLIP-seq
MIRT1019062	hsa-miR-1273e	CLIP-seq
MIRT1019063	hsa-miR-1280	CLIP-seq
MIRT1019064	hsa-miR-1283	CLIP-seq
MIRT1019065	hsa-miR-1287	CLIP-seq
MIRT1019066	hsa-miR-1288	CLIP-seq
MIRT1019067	hsa-miR-1297	CLIP-seq
MIRT1019068	hsa-miR-1304	CLIP-seq
MIRT1019069	hsa-miR-1323	CLIP-seq
MIRT1019070	hsa-miR-139-5p	CLIP-seq
MIRT1019071	hsa-miR-140-5p	CLIP-seq
MIRT1019072	hsa-miR-141	CLIP-seq
MIRT1019073	hsa-miR-142-5p	CLIP-seq
MIRT1019074	hsa-miR-150	CLIP-seq
MIRT1019075	hsa-miR-1915	CLIP-seq
MIRT1019076	hsa-miR-194	CLIP-seq
MIRT1019077	hsa-miR-200a	CLIP-seq
MIRT1019078	hsa-miR-203	CLIP-seq
MIRT1019079	hsa-miR-2054	CLIP-seq
MIRT1019080	hsa-miR-24	CLIP-seq
MIRT1019081	hsa-miR-26a	CLIP-seq
MIRT1019082	hsa-miR-26b	CLIP-seq
MIRT1019083	hsa-miR-300	CLIP-seq
MIRT1019084	hsa-miR-3122	CLIP-seq
MIRT1019085	hsa-miR-3130-3p	CLIP-seq
MIRT1019086	hsa-miR-3135b	CLIP-seq
MIRT1019087	hsa-miR-3136-3p	CLIP-seq
MIRT1019088	hsa-miR-3142	CLIP-seq
MIRT1019089	hsa-miR-3148	CLIP-seq
MIRT1019090	hsa-miR-3153	CLIP-seq
MIRT1019091	hsa-miR-3159	CLIP-seq
MIRT1019092	hsa-miR-3168	CLIP-seq
MIRT1019093	hsa-miR-3169	CLIP-seq
MIRT1019094	hsa-miR-3170	CLIP-seq
MIRT1019095	hsa-miR-3174	CLIP-seq
MIRT1019096	hsa-miR-3201	CLIP-seq
MIRT1019097	hsa-miR-320a	CLIP-seq
MIRT1019098	hsa-miR-320b	CLIP-seq
MIRT1019099	hsa-miR-320c	CLIP-seq
MIRT1019100	hsa-miR-320d	CLIP-seq
MIRT1019101	hsa-miR-326	CLIP-seq
MIRT1019102	hsa-miR-330-5p	CLIP-seq
MIRT1019103	hsa-miR-340	CLIP-seq
MIRT1019104	hsa-miR-34b	CLIP-seq
MIRT1019105	hsa-miR-3607-5p	CLIP-seq
MIRT1019106	hsa-miR-3613-3p	CLIP-seq
MIRT1019107	hsa-miR-3614-5p	CLIP-seq
MIRT1019108	hsa-miR-3620	CLIP-seq
MIRT1019109	hsa-miR-3647-3p	CLIP-seq
MIRT1019110	hsa-miR-3648	CLIP-seq
MIRT1019111	hsa-miR-3650	CLIP-seq
MIRT1019112	hsa-miR-3652	CLIP-seq
MIRT1019113	hsa-miR-3658	CLIP-seq
MIRT1019114	hsa-miR-3671	CLIP-seq
MIRT1019115	hsa-miR-3672	CLIP-seq
MIRT1019116	hsa-miR-3675-3p	CLIP-seq
MIRT1019117	hsa-miR-3682-5p	CLIP-seq
MIRT1019118	hsa-miR-3689a-3p	CLIP-seq
MIRT1019119	hsa-miR-3689c	CLIP-seq
MIRT1019120	hsa-miR-381	CLIP-seq
MIRT1019121	hsa-miR-3913-5p	CLIP-seq
MIRT1019122	hsa-miR-3917	CLIP-seq
MIRT1019123	hsa-miR-3926	CLIP-seq
MIRT1019124	hsa-miR-3938	CLIP-seq
MIRT1019125	hsa-miR-3973	CLIP-seq
MIRT1019126	hsa-miR-3976	CLIP-seq
MIRT1019127	hsa-miR-412	CLIP-seq
MIRT1019128	hsa-miR-421	CLIP-seq
MIRT1019129	hsa-miR-4252	CLIP-seq
MIRT1019130	hsa-miR-4282	CLIP-seq
MIRT1019131	hsa-miR-4284	CLIP-seq
MIRT1019132	hsa-miR-4429	CLIP-seq
MIRT1019133	hsa-miR-4430	CLIP-seq
MIRT1019134	hsa-miR-4432	CLIP-seq
MIRT1019135	hsa-miR-4433	CLIP-seq
MIRT1019136	hsa-miR-4438	CLIP-seq
MIRT1019137	hsa-miR-4453	CLIP-seq
MIRT1019138	hsa-miR-4459	CLIP-seq
MIRT1019139	hsa-miR-4465	CLIP-seq
MIRT1019140	hsa-miR-4477a	CLIP-seq
MIRT1019141	hsa-miR-4480	CLIP-seq
MIRT1019142	hsa-miR-450b-3p	CLIP-seq
MIRT1019143	hsa-miR-4538	CLIP-seq
MIRT1019144	hsa-miR-4661-5p	CLIP-seq
MIRT1019145	hsa-miR-4662a-5p	CLIP-seq
MIRT1019146	hsa-miR-4667-5p	CLIP-seq
MIRT1019147	hsa-miR-4668-5p	CLIP-seq
MIRT1019148	hsa-miR-4679	CLIP-seq
MIRT1019149	hsa-miR-4684-5p	CLIP-seq
MIRT1019150	hsa-miR-4695-3p	CLIP-seq
MIRT1019151	hsa-miR-4699-3p	CLIP-seq
MIRT1019152	hsa-miR-4700-5p	CLIP-seq
MIRT1019153	hsa-miR-4704-5p	CLIP-seq
MIRT1019154	hsa-miR-4716-5p	CLIP-seq
MIRT1019155	hsa-miR-4717-5p	CLIP-seq
MIRT1019156	hsa-miR-4728-5p	CLIP-seq
MIRT1019157	hsa-miR-4729	CLIP-seq
MIRT1019158	hsa-miR-4733-5p	CLIP-seq
MIRT1019159	hsa-miR-4761-5p	CLIP-seq
MIRT1019160	hsa-miR-4766-3p	CLIP-seq
MIRT1019161	hsa-miR-4768-3p	CLIP-seq
MIRT1019162	hsa-miR-4777-5p	CLIP-seq
MIRT1019163	hsa-miR-4786-5p	CLIP-seq
MIRT1019164	hsa-miR-4791	CLIP-seq
MIRT1019165	hsa-miR-4795-3p	CLIP-seq
MIRT1019166	hsa-miR-4796-5p	CLIP-seq
MIRT1019167	hsa-miR-4797-5p	CLIP-seq
MIRT1019168	hsa-miR-4799-5p	CLIP-seq
MIRT1019169	hsa-miR-494	CLIP-seq
MIRT1019170	hsa-miR-5095	CLIP-seq
MIRT1019171	hsa-miR-513a-3p	CLIP-seq
MIRT1019172	hsa-miR-518d-5p	CLIP-seq
MIRT1019173	hsa-miR-519b-5p	CLIP-seq
MIRT1019174	hsa-miR-519c-5p	CLIP-seq
MIRT1019175	hsa-miR-520c-5p	CLIP-seq
MIRT1019176	hsa-miR-526a	CLIP-seq
MIRT1019177	hsa-miR-532-3p	CLIP-seq
MIRT1019178	hsa-miR-548l	CLIP-seq
MIRT1019179	hsa-miR-548o	CLIP-seq
MIRT1019180	hsa-miR-548p	CLIP-seq
MIRT1019181	hsa-miR-548s	CLIP-seq
MIRT1019182	hsa-miR-579	CLIP-seq
MIRT1019183	hsa-miR-590-3p	CLIP-seq
MIRT1019184	hsa-miR-603	CLIP-seq
MIRT1019185	hsa-miR-607	CLIP-seq
MIRT1019186	hsa-miR-630	CLIP-seq
MIRT1019187	hsa-miR-635	CLIP-seq
MIRT1019188	hsa-miR-637	CLIP-seq
MIRT1019189	hsa-miR-656	CLIP-seq
MIRT1019190	hsa-miR-663b	CLIP-seq
MIRT1019191	hsa-miR-665	CLIP-seq
MIRT1019192	hsa-miR-769-3p	CLIP-seq
MIRT1019193	hsa-miR-769-5p	CLIP-seq
MIRT1019194	hsa-miR-921	CLIP-seq
MIRT1019195	hsa-miR-944	CLIP-seq
MIRT2001734	hsa-miR-103b	CLIP-seq
MIRT1019056	hsa-miR-1224-3p	CLIP-seq
MIRT2001735	hsa-miR-1226	CLIP-seq
MIRT2001736	hsa-miR-1228	CLIP-seq
MIRT2001737	hsa-miR-1237	CLIP-seq
MIRT1019057	hsa-miR-1245	CLIP-seq
MIRT2001738	hsa-miR-1248	CLIP-seq
MIRT2001739	hsa-miR-1251	CLIP-seq
MIRT1019059	hsa-miR-1252	CLIP-seq
MIRT2001740	hsa-miR-1253	CLIP-seq
MIRT2001741	hsa-miR-1262	CLIP-seq
MIRT2001742	hsa-miR-1266	CLIP-seq
MIRT1019064	hsa-miR-1283	CLIP-seq
MIRT2001743	hsa-miR-129-5p	CLIP-seq
MIRT1019069	hsa-miR-1323	CLIP-seq
MIRT2001744	hsa-miR-134	CLIP-seq
MIRT1019074	hsa-miR-150	CLIP-seq
MIRT1019079	hsa-miR-2054	CLIP-seq
MIRT2001745	hsa-miR-21	CLIP-seq
MIRT2001746	hsa-miR-216a	CLIP-seq
MIRT2001747	hsa-miR-29a	CLIP-seq
MIRT2001748	hsa-miR-29b	CLIP-seq
MIRT2001749	hsa-miR-29c	CLIP-seq
MIRT1019083	hsa-miR-300	CLIP-seq
MIRT2001750	hsa-miR-3065-3p	CLIP-seq
MIRT2001751	hsa-miR-3118	CLIP-seq
MIRT1019084	hsa-miR-3122	CLIP-seq
MIRT1019085	hsa-miR-3130-3p	CLIP-seq
MIRT1019086	hsa-miR-3135b	CLIP-seq
MIRT2001752	hsa-miR-3150a-3p	CLIP-seq
MIRT2001753	hsa-miR-3165	CLIP-seq
MIRT1019095	hsa-miR-3174	CLIP-seq
MIRT2001754	hsa-miR-3175	CLIP-seq
MIRT1019106	hsa-miR-3613-3p	CLIP-seq
MIRT1019107	hsa-miR-3614-5p	CLIP-seq
MIRT1019111	hsa-miR-3650	CLIP-seq
MIRT1019112	hsa-miR-3652	CLIP-seq
MIRT2001755	hsa-miR-3657	CLIP-seq
MIRT2001756	hsa-miR-3664-3p	CLIP-seq
MIRT2001757	hsa-miR-3667-3p	CLIP-seq
MIRT1019115	hsa-miR-3672	CLIP-seq
MIRT2001758	hsa-miR-3674	CLIP-seq
MIRT1019116	hsa-miR-3675-3p	CLIP-seq
MIRT1019118	hsa-miR-3689a-3p	CLIP-seq
MIRT1019119	hsa-miR-3689c	CLIP-seq
MIRT1019120	hsa-miR-381	CLIP-seq
MIRT1019121	hsa-miR-3913-5p	CLIP-seq
MIRT1019123	hsa-miR-3926	CLIP-seq
MIRT2001759	hsa-miR-3929	CLIP-seq
MIRT2001760	hsa-miR-3943	CLIP-seq
MIRT1019126	hsa-miR-3976	CLIP-seq
MIRT1019129	hsa-miR-4252	CLIP-seq
MIRT2001761	hsa-miR-4270	CLIP-seq
MIRT1019131	hsa-miR-4284	CLIP-seq
MIRT2001762	hsa-miR-4323	CLIP-seq
MIRT2001763	hsa-miR-4329	CLIP-seq
MIRT2001764	hsa-miR-4419b	CLIP-seq
MIRT2001765	hsa-miR-4426	CLIP-seq
MIRT1019133	hsa-miR-4430	CLIP-seq
MIRT1019135	hsa-miR-4433	CLIP-seq
MIRT1019136	hsa-miR-4438	CLIP-seq
MIRT2001766	hsa-miR-4441	CLIP-seq
MIRT1019137	hsa-miR-4453	CLIP-seq
MIRT1019138	hsa-miR-4459	CLIP-seq
MIRT1019140	hsa-miR-4477a	CLIP-seq
MIRT2001767	hsa-miR-4478	CLIP-seq
MIRT2001768	hsa-miR-4518	CLIP-seq
MIRT2001769	hsa-miR-451b	CLIP-seq
MIRT1019143	hsa-miR-4538	CLIP-seq
MIRT2001770	hsa-miR-4640-5p	CLIP-seq
MIRT2001771	hsa-miR-4647	CLIP-seq
MIRT2001772	hsa-miR-4662b	CLIP-seq
MIRT1019147	hsa-miR-4668-5p	CLIP-seq
MIRT2001773	hsa-miR-4669	CLIP-seq
MIRT1019148	hsa-miR-4679	CLIP-seq
MIRT1019149	hsa-miR-4684-5p	CLIP-seq
MIRT2001774	hsa-miR-4688	CLIP-seq
MIRT2001775	hsa-miR-4691-3p	CLIP-seq
MIRT1019150	hsa-miR-4695-3p	CLIP-seq
MIRT2001776	hsa-miR-4701-3p	CLIP-seq
MIRT2001777	hsa-miR-4708-3p	CLIP-seq
MIRT2001778	hsa-miR-4717-3p	CLIP-seq
MIRT2001779	hsa-miR-4726-5p	CLIP-seq
MIRT1019156	hsa-miR-4728-5p	CLIP-seq
MIRT1019158	hsa-miR-4733-5p	CLIP-seq
MIRT2001780	hsa-miR-4735-5p	CLIP-seq
MIRT1019159	hsa-miR-4761-5p	CLIP-seq
MIRT2001781	hsa-miR-4763-5p	CLIP-seq
MIRT1019160	hsa-miR-4766-3p	CLIP-seq
MIRT1019161	hsa-miR-4768-3p	CLIP-seq
MIRT2001782	hsa-miR-4775	CLIP-seq
MIRT1019163	hsa-miR-4786-5p	CLIP-seq
MIRT2001783	hsa-miR-4794	CLIP-seq
MIRT1019165	hsa-miR-4795-3p	CLIP-seq
MIRT2001784	hsa-miR-485-5p	CLIP-seq
MIRT2001785	hsa-miR-501-3p	CLIP-seq
MIRT2001786	hsa-miR-502-3p	CLIP-seq
MIRT1019170	hsa-miR-5095	CLIP-seq
MIRT2001787	hsa-miR-520d-5p	CLIP-seq
MIRT2001788	hsa-miR-524-5p	CLIP-seq
MIRT1019177	hsa-miR-532-3p	CLIP-seq
MIRT2001789	hsa-miR-542-3p	CLIP-seq
MIRT2001790	hsa-miR-548a-3p	CLIP-seq
MIRT2001791	hsa-miR-548e	CLIP-seq
MIRT2001792	hsa-miR-548f	CLIP-seq
MIRT2001793	hsa-miR-548g	CLIP-seq
MIRT1019179	hsa-miR-548o	CLIP-seq
MIRT1019181	hsa-miR-548s	CLIP-seq
MIRT2001794	hsa-miR-550a	CLIP-seq
MIRT2001795	hsa-miR-580	CLIP-seq
MIRT1019183	hsa-miR-590-3p	CLIP-seq
MIRT2001796	hsa-miR-590-5p	CLIP-seq
MIRT2001797	hsa-miR-596	CLIP-seq
MIRT1019187	hsa-miR-635	CLIP-seq
MIRT1019189	hsa-miR-656	CLIP-seq
MIRT2001798	hsa-miR-661	CLIP-seq
MIRT1019191	hsa-miR-665	CLIP-seq
MIRT2001799	hsa-miR-767-5p	CLIP-seq
MIRT1019193	hsa-miR-769-5p	CLIP-seq
MIRT2001800	hsa-miR-890	CLIP-seq
MIRT2001801	hsa-miR-939	CLIP-seq
MIRT2001802	hsa-miR-942	CLIP-seq
MIRT1019055	hsa-miR-1207-3p	CLIP-seq
MIRT2001736	hsa-miR-1228	CLIP-seq
MIRT1019059	hsa-miR-1252	CLIP-seq
MIRT2001740	hsa-miR-1253	CLIP-seq
MIRT2234793	hsa-miR-1256	CLIP-seq
MIRT2001741	hsa-miR-1262	CLIP-seq
MIRT2234794	hsa-miR-1267	CLIP-seq
MIRT1019062	hsa-miR-1273e	CLIP-seq
MIRT2234795	hsa-miR-128	CLIP-seq
MIRT2234796	hsa-miR-1289	CLIP-seq
MIRT1019068	hsa-miR-1304	CLIP-seq
MIRT1019069	hsa-miR-1323	CLIP-seq
MIRT2001744	hsa-miR-134	CLIP-seq
MIRT1019071	hsa-miR-140-5p	CLIP-seq
MIRT2234797	hsa-miR-146a	CLIP-seq
MIRT2234798	hsa-miR-146b-5p	CLIP-seq
MIRT1019074	hsa-miR-150	CLIP-seq
MIRT2234799	hsa-miR-185	CLIP-seq
MIRT2234800	hsa-miR-18a	CLIP-seq
MIRT2234801	hsa-miR-18b	CLIP-seq
MIRT2234802	hsa-miR-1911	CLIP-seq
MIRT2234803	hsa-miR-192	CLIP-seq
MIRT2234804	hsa-miR-200b	CLIP-seq
MIRT2234805	hsa-miR-200c	CLIP-seq
MIRT2234806	hsa-miR-215	CLIP-seq
MIRT2234807	hsa-miR-23a	CLIP-seq
MIRT2234808	hsa-miR-23b	CLIP-seq
MIRT2234809	hsa-miR-23c	CLIP-seq
MIRT2234810	hsa-miR-27a	CLIP-seq
MIRT2234811	hsa-miR-27b	CLIP-seq
MIRT1019083	hsa-miR-300	CLIP-seq
MIRT2001751	hsa-miR-3118	CLIP-seq
MIRT1019084	hsa-miR-3122	CLIP-seq
MIRT2234812	hsa-miR-3123	CLIP-seq
MIRT2234813	hsa-miR-3127-3p	CLIP-seq
MIRT1019085	hsa-miR-3130-3p	CLIP-seq
MIRT1019086	hsa-miR-3135b	CLIP-seq
MIRT2234814	hsa-miR-3143	CLIP-seq
MIRT1019091	hsa-miR-3159	CLIP-seq
MIRT2234815	hsa-miR-3164	CLIP-seq
MIRT2001753	hsa-miR-3165	CLIP-seq
MIRT2234816	hsa-miR-3171	CLIP-seq
MIRT1019095	hsa-miR-3174	CLIP-seq
MIRT2234817	hsa-miR-3177-5p	CLIP-seq
MIRT1019106	hsa-miR-3613-3p	CLIP-seq
MIRT1019107	hsa-miR-3614-5p	CLIP-seq
MIRT1019108	hsa-miR-3620	CLIP-seq
MIRT1019111	hsa-miR-3650	CLIP-seq
MIRT1019112	hsa-miR-3652	CLIP-seq
MIRT2001757	hsa-miR-3667-3p	CLIP-seq
MIRT1019115	hsa-miR-3672	CLIP-seq
MIRT1019118	hsa-miR-3689a-3p	CLIP-seq
MIRT1019119	hsa-miR-3689c	CLIP-seq
MIRT2234818	hsa-miR-371-5p	CLIP-seq
MIRT2234819	hsa-miR-371b-5p	CLIP-seq
MIRT2234820	hsa-miR-374c	CLIP-seq
MIRT2234821	hsa-miR-380	CLIP-seq
MIRT1019120	hsa-miR-381	CLIP-seq
MIRT1019121	hsa-miR-3913-5p	CLIP-seq
MIRT2001759	hsa-miR-3929	CLIP-seq
MIRT1019128	hsa-miR-421	CLIP-seq
MIRT2234822	hsa-miR-425	CLIP-seq
MIRT1019129	hsa-miR-4252	CLIP-seq
MIRT2234823	hsa-miR-429	CLIP-seq
MIRT2234824	hsa-miR-4299	CLIP-seq
MIRT2234825	hsa-miR-4306	CLIP-seq
MIRT2001763	hsa-miR-4329	CLIP-seq
MIRT2234826	hsa-miR-4418	CLIP-seq
MIRT2001764	hsa-miR-4419b	CLIP-seq
MIRT1019133	hsa-miR-4430	CLIP-seq
MIRT1019135	hsa-miR-4433	CLIP-seq
MIRT1019136	hsa-miR-4438	CLIP-seq
MIRT1019137	hsa-miR-4453	CLIP-seq
MIRT1019138	hsa-miR-4459	CLIP-seq
MIRT2001767	hsa-miR-4478	CLIP-seq
MIRT1019141	hsa-miR-4480	CLIP-seq
MIRT2234827	hsa-miR-4517	CLIP-seq
MIRT2001769	hsa-miR-451b	CLIP-seq
MIRT1019143	hsa-miR-4538	CLIP-seq
MIRT2234828	hsa-miR-4642	CLIP-seq
MIRT2234829	hsa-miR-4643	CLIP-seq
MIRT2234830	hsa-miR-4644	CLIP-seq
MIRT1019144	hsa-miR-4661-5p	CLIP-seq
MIRT1019148	hsa-miR-4679	CLIP-seq
MIRT2234831	hsa-miR-4693-3p	CLIP-seq
MIRT1019150	hsa-miR-4695-3p	CLIP-seq
MIRT2234832	hsa-miR-4698	CLIP-seq
MIRT1019151	hsa-miR-4699-3p	CLIP-seq
MIRT2001776	hsa-miR-4701-3p	CLIP-seq
MIRT2001777	hsa-miR-4708-3p	CLIP-seq
MIRT2234833	hsa-miR-4709-5p	CLIP-seq
MIRT2234834	hsa-miR-4713-5p	CLIP-seq
MIRT1019156	hsa-miR-4728-5p	CLIP-seq
MIRT2234835	hsa-miR-4735-3p	CLIP-seq
MIRT2001780	hsa-miR-4735-5p	CLIP-seq
MIRT1019159	hsa-miR-4761-5p	CLIP-seq
MIRT1019160	hsa-miR-4766-3p	CLIP-seq
MIRT1019161	hsa-miR-4768-3p	CLIP-seq
MIRT2001782	hsa-miR-4775	CLIP-seq
MIRT1019163	hsa-miR-4786-5p	CLIP-seq
MIRT2001783	hsa-miR-4794	CLIP-seq
MIRT2234836	hsa-miR-4796-3p	CLIP-seq
MIRT1019167	hsa-miR-4797-5p	CLIP-seq
MIRT2234837	hsa-miR-4803	CLIP-seq
MIRT2001784	hsa-miR-485-5p	CLIP-seq
MIRT2234838	hsa-miR-498	CLIP-seq
MIRT2001785	hsa-miR-501-3p	CLIP-seq
MIRT2001786	hsa-miR-502-3p	CLIP-seq
MIRT2234839	hsa-miR-509-3-5p	CLIP-seq
MIRT1019170	hsa-miR-5095	CLIP-seq
MIRT2234840	hsa-miR-509-5p	CLIP-seq
MIRT1019171	hsa-miR-513a-3p	CLIP-seq
MIRT2001787	hsa-miR-520d-5p	CLIP-seq
MIRT2234841	hsa-miR-520g	CLIP-seq
MIRT2234842	hsa-miR-520h	CLIP-seq
MIRT2001788	hsa-miR-524-5p	CLIP-seq
MIRT1019177	hsa-miR-532-3p	CLIP-seq
MIRT2234843	hsa-miR-548aa	CLIP-seq
MIRT2001793	hsa-miR-548g	CLIP-seq
MIRT1019179	hsa-miR-548o	CLIP-seq
MIRT2234844	hsa-miR-570	CLIP-seq
MIRT2001795	hsa-miR-580	CLIP-seq
MIRT2234845	hsa-miR-589	CLIP-seq
MIRT1019183	hsa-miR-590-3p	CLIP-seq
MIRT1019186	hsa-miR-630	CLIP-seq
MIRT1019187	hsa-miR-635	CLIP-seq
MIRT2234846	hsa-miR-642b	CLIP-seq
MIRT2234847	hsa-miR-655	CLIP-seq
MIRT2001798	hsa-miR-661	CLIP-seq
MIRT2234848	hsa-miR-664	CLIP-seq
MIRT1019191	hsa-miR-665	CLIP-seq
MIRT2001799	hsa-miR-767-5p	CLIP-seq
MIRT1019193	hsa-miR-769-5p	CLIP-seq
MIRT2001800	hsa-miR-890	CLIP-seq
MIRT1019194	hsa-miR-921	CLIP-seq
MIRT2234849	hsa-miR-943	CLIP-seq
MIRT1019195	hsa-miR-944	CLIP-seq
MIRT1019086	hsa-miR-3135b	CLIP-seq
MIRT1019111	hsa-miR-3650	CLIP-seq
MIRT1019112	hsa-miR-3652	CLIP-seq
MIRT1019133	hsa-miR-4430	CLIP-seq
MIRT2001736	hsa-miR-1228	CLIP-seq
MIRT1019069	hsa-miR-1323	CLIP-seq
MIRT2001744	hsa-miR-134	CLIP-seq
MIRT2001751	hsa-miR-3118	CLIP-seq
MIRT2450274	hsa-miR-3120-5p	CLIP-seq
MIRT2234815	hsa-miR-3164	CLIP-seq
MIRT2450275	hsa-miR-3664-5p	CLIP-seq
MIRT2234818	hsa-miR-371-5p	CLIP-seq
MIRT2234819	hsa-miR-371b-5p	CLIP-seq
MIRT1019134	hsa-miR-4432	CLIP-seq
MIRT1019136	hsa-miR-4438	CLIP-seq
MIRT1019145	hsa-miR-4662a-5p	CLIP-seq
MIRT2450276	hsa-miR-4676-5p	CLIP-seq
MIRT1019149	hsa-miR-4684-5p	CLIP-seq
MIRT2450277	hsa-miR-4755-3p	CLIP-seq
MIRT2001783	hsa-miR-4794	CLIP-seq
MIRT2450278	hsa-miR-495	CLIP-seq
MIRT2001785	hsa-miR-501-3p	CLIP-seq
MIRT2001786	hsa-miR-502-3p	CLIP-seq
MIRT1019170	hsa-miR-5095	CLIP-seq
MIRT2001790	hsa-miR-548a-3p	CLIP-seq
MIRT2450279	hsa-miR-548c-3p	CLIP-seq
MIRT2001791	hsa-miR-548e	CLIP-seq
MIRT2001792	hsa-miR-548f	CLIP-seq
MIRT1019179	hsa-miR-548o	CLIP-seq
MIRT2450280	hsa-miR-575	CLIP-seq
MIRT2450281	hsa-miR-593	CLIP-seq
MIRT2001799	hsa-miR-767-5p	CLIP-seq
MIRT2001736	hsa-miR-1228	CLIP-seq
MIRT2001744	hsa-miR-134	CLIP-seq
MIRT2001751	hsa-miR-3118	CLIP-seq
MIRT2234815	hsa-miR-3164	CLIP-seq
MIRT1019136	hsa-miR-4438	CLIP-seq
MIRT2001783	hsa-miR-4794	CLIP-seq
MIRT2001785	hsa-miR-501-3p	CLIP-seq
MIRT2001786	hsa-miR-502-3p	CLIP-seq
MIRT1019170	hsa-miR-5095	CLIP-seq
MIRT2001799	hsa-miR-767-5p	CLIP-seq
MIRT2001736	hsa-miR-1228	CLIP-seq
MIRT2001740	hsa-miR-1253	CLIP-seq
MIRT2001741	hsa-miR-1262	CLIP-seq
MIRT1019062	hsa-miR-1273e	CLIP-seq
MIRT1019064	hsa-miR-1283	CLIP-seq
MIRT1019066	hsa-miR-1288	CLIP-seq
MIRT1019068	hsa-miR-1304	CLIP-seq
MIRT1019069	hsa-miR-1323	CLIP-seq
MIRT2001744	hsa-miR-134	CLIP-seq
MIRT2234800	hsa-miR-18a	CLIP-seq
MIRT2234801	hsa-miR-18b	CLIP-seq
MIRT1019075	hsa-miR-1915	CLIP-seq
MIRT1019079	hsa-miR-2054	CLIP-seq
MIRT2001751	hsa-miR-3118	CLIP-seq
MIRT2450274	hsa-miR-3120-5p	CLIP-seq
MIRT2538752	hsa-miR-3121-3p	CLIP-seq
MIRT1019084	hsa-miR-3122	CLIP-seq
MIRT2234812	hsa-miR-3123	CLIP-seq
MIRT1019085	hsa-miR-3130-3p	CLIP-seq
MIRT1019086	hsa-miR-3135b	CLIP-seq
MIRT2234815	hsa-miR-3164	CLIP-seq
MIRT1019093	hsa-miR-3169	CLIP-seq
MIRT1019095	hsa-miR-3174	CLIP-seq
MIRT1019104	hsa-miR-34b	CLIP-seq
MIRT1019107	hsa-miR-3614-5p	CLIP-seq
MIRT1019111	hsa-miR-3650	CLIP-seq
MIRT1019112	hsa-miR-3652	CLIP-seq
MIRT2450275	hsa-miR-3664-5p	CLIP-seq
MIRT1019115	hsa-miR-3672	CLIP-seq
MIRT1019118	hsa-miR-3689a-3p	CLIP-seq
MIRT1019119	hsa-miR-3689c	CLIP-seq
MIRT2234818	hsa-miR-371-5p	CLIP-seq
MIRT2234819	hsa-miR-371b-5p	CLIP-seq
MIRT1019121	hsa-miR-3913-5p	CLIP-seq
MIRT1019126	hsa-miR-3976	CLIP-seq
MIRT1019129	hsa-miR-4252	CLIP-seq
MIRT2234826	hsa-miR-4418	CLIP-seq
MIRT1019133	hsa-miR-4430	CLIP-seq
MIRT1019134	hsa-miR-4432	CLIP-seq
MIRT1019135	hsa-miR-4433	CLIP-seq
MIRT1019136	hsa-miR-4438	CLIP-seq
MIRT1019137	hsa-miR-4453	CLIP-seq
MIRT1019140	hsa-miR-4477a	CLIP-seq
MIRT1019143	hsa-miR-4538	CLIP-seq
MIRT1019145	hsa-miR-4662a-5p	CLIP-seq
MIRT2450276	hsa-miR-4676-5p	CLIP-seq
MIRT1019148	hsa-miR-4679	CLIP-seq
MIRT1019149	hsa-miR-4684-5p	CLIP-seq
MIRT1019150	hsa-miR-4695-3p	CLIP-seq
MIRT2001776	hsa-miR-4701-3p	CLIP-seq
MIRT1019156	hsa-miR-4728-5p	CLIP-seq
MIRT1019158	hsa-miR-4733-5p	CLIP-seq
MIRT2234835	hsa-miR-4735-3p	CLIP-seq
MIRT2001780	hsa-miR-4735-5p	CLIP-seq
MIRT2450277	hsa-miR-4755-3p	CLIP-seq
MIRT2001782	hsa-miR-4775	CLIP-seq
MIRT1019163	hsa-miR-4786-5p	CLIP-seq
MIRT2001783	hsa-miR-4794	CLIP-seq
MIRT2450278	hsa-miR-495	CLIP-seq
MIRT2001785	hsa-miR-501-3p	CLIP-seq
MIRT2001786	hsa-miR-502-3p	CLIP-seq
MIRT2234839	hsa-miR-509-3-5p	CLIP-seq
MIRT1019170	hsa-miR-5095	CLIP-seq
MIRT2234840	hsa-miR-509-5p	CLIP-seq
MIRT2538753	hsa-miR-539	CLIP-seq
MIRT2001789	hsa-miR-542-3p	CLIP-seq
MIRT2001790	hsa-miR-548a-3p	CLIP-seq
MIRT2450279	hsa-miR-548c-3p	CLIP-seq
MIRT2001791	hsa-miR-548e	CLIP-seq
MIRT2001792	hsa-miR-548f	CLIP-seq
MIRT1019179	hsa-miR-548o	CLIP-seq
MIRT2234844	hsa-miR-570	CLIP-seq
MIRT2450280	hsa-miR-575	CLIP-seq
MIRT2001795	hsa-miR-580	CLIP-seq
MIRT1019183	hsa-miR-590-3p	CLIP-seq
MIRT2450281	hsa-miR-593	CLIP-seq
MIRT1019187	hsa-miR-635	CLIP-seq
MIRT2001798	hsa-miR-661	CLIP-seq
MIRT1019191	hsa-miR-665	CLIP-seq
MIRT2001799	hsa-miR-767-5p	CLIP-seq
MIRT1019193	hsa-miR-769-5p	CLIP-seq
MIRT1019194	hsa-miR-921	CLIP-seq
MIRT2001736	hsa-miR-1228	CLIP-seq
MIRT2001740	hsa-miR-1253	CLIP-seq
MIRT2001741	hsa-miR-1262	CLIP-seq
MIRT1019069	hsa-miR-1323	CLIP-seq
MIRT1019075	hsa-miR-1915	CLIP-seq
MIRT2450274	hsa-miR-3120-5p	CLIP-seq
MIRT2234812	hsa-miR-3123	CLIP-seq
MIRT1019085	hsa-miR-3130-3p	CLIP-seq
MIRT1019086	hsa-miR-3135b	CLIP-seq
MIRT1019095	hsa-miR-3174	CLIP-seq
MIRT1019104	hsa-miR-34b	CLIP-seq
MIRT1019107	hsa-miR-3614-5p	CLIP-seq
MIRT1019111	hsa-miR-3650	CLIP-seq
MIRT1019112	hsa-miR-3652	CLIP-seq
MIRT2450275	hsa-miR-3664-5p	CLIP-seq
MIRT1019118	hsa-miR-3689a-3p	CLIP-seq
MIRT1019119	hsa-miR-3689c	CLIP-seq
MIRT2234818	hsa-miR-371-5p	CLIP-seq
MIRT2234819	hsa-miR-371b-5p	CLIP-seq
MIRT1019126	hsa-miR-3976	CLIP-seq
MIRT1019129	hsa-miR-4252	CLIP-seq
MIRT1019133	hsa-miR-4430	CLIP-seq
MIRT1019134	hsa-miR-4432	CLIP-seq
MIRT1019136	hsa-miR-4438	CLIP-seq
MIRT1019137	hsa-miR-4453	CLIP-seq
MIRT1019143	hsa-miR-4538	CLIP-seq
MIRT1019145	hsa-miR-4662a-5p	CLIP-seq
MIRT2450276	hsa-miR-4676-5p	CLIP-seq
MIRT1019148	hsa-miR-4679	CLIP-seq
MIRT1019149	hsa-miR-4684-5p	CLIP-seq
MIRT1019150	hsa-miR-4695-3p	CLIP-seq
MIRT2001776	hsa-miR-4701-3p	CLIP-seq
MIRT1019156	hsa-miR-4728-5p	CLIP-seq
MIRT2450277	hsa-miR-4755-3p	CLIP-seq
MIRT1019163	hsa-miR-4786-5p	CLIP-seq
MIRT2001783	hsa-miR-4794	CLIP-seq
MIRT2450278	hsa-miR-495	CLIP-seq
MIRT2001785	hsa-miR-501-3p	CLIP-seq
MIRT2001786	hsa-miR-502-3p	CLIP-seq
MIRT1019170	hsa-miR-5095	CLIP-seq
MIRT2001789	hsa-miR-542-3p	CLIP-seq
MIRT2001790	hsa-miR-548a-3p	CLIP-seq
MIRT2450279	hsa-miR-548c-3p	CLIP-seq
MIRT2001791	hsa-miR-548e	CLIP-seq
MIRT2001792	hsa-miR-548f	CLIP-seq
MIRT1019179	hsa-miR-548o	CLIP-seq
MIRT2450280	hsa-miR-575	CLIP-seq
MIRT2001795	hsa-miR-580	CLIP-seq
MIRT2450281	hsa-miR-593	CLIP-seq
MIRT1019187	hsa-miR-635	CLIP-seq
MIRT2001798	hsa-miR-661	CLIP-seq
MIRT2001799	hsa-miR-767-5p	CLIP-seq
MIRT1019193	hsa-miR-769-5p	CLIP-seq
MIRT1019194	hsa-miR-921	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000811	Component	GINS complex	IBA	21873635
GO:0001833	Process	Inner cell mass cell proliferation	IEA
GO:0005634	Component	Nucleus	IDA	10942595
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IDA	10942595
GO:0006271	Process	DNA strand elongation involved in DNA replication	TAS
GO:0071162	Component	CMG complex	ISS
GO:1902983	Process	DNA strand elongation involved in mitotic DNA replication	IBA	21873635

MIM	HGNC	e!Ensembl
610608	28980	ENSG00000101003

Protein

UniProt ID

Q14691

Protein name

DNA replication complex GINS protein PSF1 (GINS complex subunit 1)

Protein function

Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks (PubMed:17417653, PubMed:28414293). GINS complex is a core component of C

PDB

2E9X , 2EHO , 2Q9Q , 6XTX , 6XTY , 7PFO , 7PLO , 8B9D , 8OK2

Family and domains

Sequence

MFCEKAMELIRELHRAPEGQLPAFNEDGLRQVLEEMKALYEQNQSDVNEAKSGGRSDLIP
TIKFRHCSLLRNRRCTVAYLYDRLLRIRALRWEYGSVLPNALRFHMAAEEMEWFNNYKRS
LATYMRSLGGDEGLDITQDMKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRW
KCEQLIRQGVLEHILS

Sequence length

196

Interactions

View interactions

	Reactome
			Unwinding of DNA

Associated diseases

Show/Hide Causal Diseases (6)

Causal
Disease name	Disease term	dbSNP ID	References
Ichthyosis	Ichthyoses	rs199766569, rs587776996, rs587777262, rs863223405, rs370031870, rs1569044747, rs200806519
Immunodeficiency	IMMUNODEFICIENCY 55	rs1565678077, rs121908002, rs1421444086, rs1565688667, rs944235493, rs121918314, rs587776713, rs137852678, rs587776714, rs128620188, rs2147483647, rs1569556522, rs137853331, rs137853332, rs179363866, rs483352928, rs121918659, rs111033580, rs111033581, rs74315290, rs193922740, rs193922741, rs104894199, rs483352927, rs104894286, rs1571865049, rs886041032, rs2069709, rs587776822, rs74315444, rs587776823, rs1315265916, rs104893893, rs104893894, rs121434560, rs387906572, rs587776853, rs104893973, rs587776854, rs587776855, rs587776857, rs104893974, rs121912715, rs1393707607, rs113994136, rs387906593, rs587776870, rs387906763, rs387906913, rs199469663, rs199469662, rs199469664, rs193922640, rs193922641, rs193922645, rs398122890, rs387907316, rs397514710, rs398122383, rs397515453, rs397514332, rs398123058, rs397518423, rs587777075, rs199676861, rs77563738, rs587777337, rs28730670, rs587777389, rs587777390, rs587777413, rs587777414, rs587777415, rs587777416, rs267608260, rs267608261, rs587778405, rs587777446, rs587777562, rs587777564, rs587777565, rs869320745, rs587777709, rs606231305, rs672601318, rs727503779, rs727503780, rs730880296, rs786200953, rs375323253, rs794729666, rs886041037, rs886041038, rs796051887, rs796051888, rs749956849, rs199641706, rs775739391, rs869312886, rs869312857, rs879253731, rs879253732, rs201025290, rs770927552, rs878853275, rs878853276, rs878853277, rs878853278, rs1567506566, rs886037920, rs886037921, rs750610248, rs200044623, rs886043118, rs886060531, rs1057519074, rs1057519075, rs1057518744, rs1057519079, rs1057518745, rs1057518746, rs1057518747, rs782178147, rs55729925, rs1064795762, rs1064794957, rs1085307649, rs745463649, rs773694113, rs1192554889, rs779575307, rs1554051075, rs1554051067, rs1554051033, rs1554067182, rs1555167566, rs1555169270, rs1555908409, rs1555719963, rs1554064929, rs768091235, rs1404084330, rs144104577, rs1553238837, rs1553243550, rs1554020278, rs1554066684, rs762678772, rs570768621, rs1443126481, rs1553721236, rs121434258, rs888230251, rs1759915032, rs1759514836, rs138156467, rs1560914625, rs755373718, rs1561423197, rs1560938296, rs200803157, rs766555082, rs201543770, rs114951157, rs775578531, rs201128237, rs778624945, rs1563340753, rs1561772403, rs1484948342, rs777878144, rs1562364898, rs1561254290, rs1569296295, rs1568815169, rs1568822574, rs1571880832, rs934523851, rs1922072844, rs1266114717, rs137869655, rs869320689, rs1571880941, rs1580875488, rs1581303476, rs1448018291, rs1390410878, rs774803573, rs1591278347, rs1602300615, rs1601340933, rs757598952, rs1181595292, rs1408683294, rs1595843113, rs1595848141, rs779560450, rs1595816926, rs1601861196, rs1601861199, rs756541321, rs1594389703, rs1594390415, rs1581401865, rs1236009877, rs753213766, rs778993919, rs1602878106, rs141698985, rs1264504989, rs1580974401, rs2093571190, rs530286781, rs2086875746, rs2089298923, rs1206185362, rs1581573705, rs1596718225, rs1004337827, rs1573613529, rs1574636674, rs1574657735, rs1574657762, rs1574672718, rs1581573640, rs1553657429, rs200666300, rs1578735747, rs1578771211, rs1578793312, rs1578795536, rs1578809101, rs1578811073, rs1578811245, rs1171694504, rs1578971328, rs140800288, rs374333820, rs1584926133, rs1585040113, rs1584409386, rs1379376784, rs1586940273, rs1587143342, rs748910652, rs1592117677, rs758555433, rs1596712783, rs34019455, rs147766868, rs751386365, rs1600631294, rs1489114116, rs1057520578, rs1603007888, rs1603008329, rs1574450161, rs1578735709, rs1403833564, rs1580262965, rs570910902, rs1589866171, rs1578999313, rs1582635229, rs1582637044, rs1580851910, rs1750760771, rs745453685, rs1249197356, rs201840561, rs1940921909, rs1941410085, rs1941465194, rs1321690789, rs1302362911, rs1730552437, rs2052705192, rs1941856970	28414293
Myelodysplasia	Myelodysplasia	rs141601766, rs1261178797
Myelodysplastic syndrome	MYELODYSPLASTIC SYNDROME	rs193303018, rs387906631, rs1576745225, rs373145711, rs752746786, rs377023736, rs373221034, rs1576749014, rs1600586587
Neutropenia	Neutropenia, Chronic neutropenia	rs879253882	28414293
Severe combined immunodeficiency disease	Combined immunodeficiency due to GINS1 deficiency	rs886037607, rs118203993, rs121908714, rs121908739, rs121908740, rs121908735, rs121908721, rs121908722, rs121908156, rs1564414523, rs1564418254, rs1564446526, rs786205074, rs121908157, rs121908159, rs786200884, rs397515357, rs104894562, rs137852624, rs137852625, rs137852626, rs137852627, rs137852507, rs137852509, rs111033619, rs111033620, rs1569480018, rs111033621, rs137852510, rs587776729, rs111033622, rs111033617, rs111033618, rs121917894, rs121917896, rs2133313409, rs121917897, rs28933392, rs104894282, rs104894283, rs104894285, rs121918570, rs121918572, rs730880318, rs104893674, rs730880319, rs104894453, rs104894454, rs104894451, rs137853206, rs777503956, rs267606645, rs267606648, rs397515390, rs193922346, rs193922347, rs193922348, rs193922349, rs193922350, rs137852508, rs193922640, rs193922641, rs193922643, rs193922645, rs193922361, rs193922364, rs193922464, rs148508754, rs193922574, rs113994174, rs606231246, rs397514671, rs397514686, rs397514755, rs199474679, rs199474685, rs199474686, rs199474681, rs150739647, rs267605358, rs886041036, rs587777335, rs587778405, rs145092287, rs587777562, rs606231256, rs200296680, rs786205456, rs786205517, rs774202259, rs786205615, rs878853261, rs786205890, rs782753385, rs746052951, rs869025224, rs869312857, rs869320660, rs869320659, rs869320658, rs879253742, rs886037924, rs886037925, rs750610248, rs886039394, rs761242509, rs886039387, rs886041043, rs886041044, rs886042051, rs886041333, rs749481781, rs1057517747, rs1057519506, rs1057523762, rs1057521062, rs1057520644, rs761583890, rs751635016, rs55729925, rs1064793248, rs1064793347, rs1064794027, rs781410769, rs1555524788, rs1486760100, rs769633203, rs1556330713, rs1555322558, rs1556330234, rs1556330755, rs1556329779, rs1556330552, rs1556329822, rs1556330286, rs1556331272, rs2146178281, rs376610445, rs757797994, rs775704953, rs1555743321, rs1564995660, rs1564995662, rs1556330249, rs144104577, rs886041796, rs1026474882, rs570768621, rs1556330562, rs1556330568, rs780014431, rs778343059, rs1555844617, rs1567629968, rs1567628757, rs1567629943, rs1567632864, rs1567632829, rs1567626023, rs1559328006, rs1561423197, rs1452483770, rs1568400897, rs1569479913, rs1568404443, rs1569480047, rs1563340753, rs368303189, rs1568431262, rs1568431102, rs1561424886, rs1602289943, rs1241698978, rs1569479994, rs1569480082, rs1602289649, rs1573261820, rs770985198, rs1589050343, rs1340132582, rs1589064324, rs1589070600, rs1213680890, rs149316157, rs1599873591, rs755706305, rs1602288051, rs1602289411, rs1602289183, rs1583513256, rs1589136659, rs1380154594, rs1011307501, rs1599876167, rs1569967422, rs1602289631, rs1573262398, rs760191638, rs1592117677, rs1640406042, rs372597855, rs1839558393, rs1839622622, rs1839957089, rs777008519, rs1233957241, rs2092261618, rs1839255008, rs1677695565, rs936493226, rs1162344514, rs991089005

Show/Hide Unknown Diseases (3)

Unknown
Disease name	Disease term	dbSNP ID	References
Dwarfism	Dwarfism
Eczema	Eczema
Liver carcinoma	Liver carcinoma		28284560

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