NOS1AP (nitric oxide synthase 1 adaptor protein)

Gene

• Entrez ID: 9722
• Gene name: Nitric oxide synthase 1 adaptor protein
• Gene symbol: NOS1AP
• Synonyms: 6330408P19Rik, CAPON, NPHS22
• Chromosome: 1
• Chromosome location: 1q23.3
• Summary: This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT044525	hsa-miR-320a	CLASH	23622248
MIRT038020	hsa-miR-423-5p	CLASH	23622248
MIRT619425	hsa-miR-8485	HITS-CLIP	23824327
MIRT619424	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619423	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT619422	hsa-miR-888-3p	HITS-CLIP	23824327
MIRT619421	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT619420	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT619419	hsa-miR-181a-2-3p	HITS-CLIP	23824327
MIRT619418	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT619417	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT630343	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT619416	hsa-miR-3151-3p	HITS-CLIP	23824327
MIRT619415	hsa-miR-6509-3p	HITS-CLIP	23824327
MIRT619414	hsa-miR-4436b-5p	HITS-CLIP	23824327
MIRT619413	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT619425	hsa-miR-8485	HITS-CLIP	23824327
MIRT619424	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619423	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT619422	hsa-miR-888-3p	HITS-CLIP	23824327
MIRT619421	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT619420	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT619419	hsa-miR-181a-2-3p	HITS-CLIP	23824327
MIRT619418	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT619417	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT630343	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT619416	hsa-miR-3151-3p	HITS-CLIP	23824327
MIRT619415	hsa-miR-6509-3p	HITS-CLIP	23824327
MIRT619414	hsa-miR-4436b-5p	HITS-CLIP	23824327
MIRT619413	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT619425	hsa-miR-8485	HITS-CLIP	23824327
MIRT619424	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619423	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT619422	hsa-miR-888-3p	HITS-CLIP	23824327
MIRT619421	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT619420	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT619419	hsa-miR-181a-2-3p	HITS-CLIP	23824327
MIRT619418	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT619417	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT619416	hsa-miR-3151-3p	HITS-CLIP	23824327
MIRT619415	hsa-miR-6509-3p	HITS-CLIP	23824327
MIRT619414	hsa-miR-4436b-5p	HITS-CLIP	23824327
MIRT619413	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT456651	hsa-miR-6768-5p	PAR-CLIP	23592263
MIRT456650	hsa-miR-1197	PAR-CLIP	23592263
MIRT456649	hsa-miR-4688	PAR-CLIP	23592263
MIRT456648	hsa-miR-6743-5p	PAR-CLIP	23592263
MIRT456647	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT038020	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT456646	hsa-miR-1914-3p	PAR-CLIP	23592263
MIRT456645	hsa-miR-5194	PAR-CLIP	23592263
MIRT456644	hsa-miR-6738-5p	PAR-CLIP	23592263
MIRT456643	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT456642	hsa-miR-3689d	PAR-CLIP	23592263
MIRT456641	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT456640	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT456639	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT456637	hsa-miR-4710	PAR-CLIP	23592263
MIRT456638	hsa-miR-7977	PAR-CLIP	23592263
MIRT456636	hsa-miR-6734-5p	PAR-CLIP	23592263
MIRT619425	hsa-miR-8485	HITS-CLIP	23824327
MIRT619424	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619423	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT619422	hsa-miR-888-3p	HITS-CLIP	23824327
MIRT619421	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT619420	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT619419	hsa-miR-181a-2-3p	HITS-CLIP	23824327
MIRT619418	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT619417	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT630343	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT619416	hsa-miR-3151-3p	HITS-CLIP	23824327
MIRT619415	hsa-miR-6509-3p	HITS-CLIP	23824327
MIRT619414	hsa-miR-4436b-5p	HITS-CLIP	23824327
MIRT619413	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT619425	hsa-miR-8485	HITS-CLIP	23824327
MIRT619424	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619423	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT619422	hsa-miR-888-3p	HITS-CLIP	23824327
MIRT619421	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT619420	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT619419	hsa-miR-181a-2-3p	HITS-CLIP	23824327
MIRT619418	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT619417	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT630343	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT619416	hsa-miR-3151-3p	HITS-CLIP	23824327
MIRT619415	hsa-miR-6509-3p	HITS-CLIP	23824327
MIRT619414	hsa-miR-4436b-5p	HITS-CLIP	23824327
MIRT619413	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT619425	hsa-miR-8485	HITS-CLIP	23824327
MIRT619424	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT619423	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT619422	hsa-miR-888-3p	HITS-CLIP	23824327
MIRT619421	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT619420	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT619419	hsa-miR-181a-2-3p	HITS-CLIP	23824327
MIRT619418	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT619417	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT619416	hsa-miR-3151-3p	HITS-CLIP	23824327
MIRT619415	hsa-miR-6509-3p	HITS-CLIP	23824327
MIRT619414	hsa-miR-4436b-5p	HITS-CLIP	23824327
MIRT619413	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT456651	hsa-miR-6768-5p	PAR-CLIP	23592263
MIRT456650	hsa-miR-1197	PAR-CLIP	23592263
MIRT456649	hsa-miR-4688	PAR-CLIP	23592263
MIRT456648	hsa-miR-6743-5p	PAR-CLIP	23592263
MIRT456647	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT038020	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT456646	hsa-miR-1914-3p	PAR-CLIP	23592263
MIRT456645	hsa-miR-5194	PAR-CLIP	23592263
MIRT456644	hsa-miR-6738-5p	PAR-CLIP	23592263
MIRT456643	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT456642	hsa-miR-3689d	PAR-CLIP	23592263
MIRT456641	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT456640	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT456639	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT456637	hsa-miR-4710	PAR-CLIP	23592263
MIRT456638	hsa-miR-7977	PAR-CLIP	23592263
MIRT456636	hsa-miR-6734-5p	PAR-CLIP	23592263
MIRT1189449	hsa-miR-106a	CLIP-seq
MIRT1189450	hsa-miR-106b	CLIP-seq
MIRT1189451	hsa-miR-1245b-5p	CLIP-seq
MIRT1189452	hsa-miR-125a-5p	CLIP-seq
MIRT1189453	hsa-miR-125b	CLIP-seq
MIRT1189454	hsa-miR-1299	CLIP-seq
MIRT1189455	hsa-miR-17	CLIP-seq
MIRT1189456	hsa-miR-20a	CLIP-seq
MIRT1189457	hsa-miR-20b	CLIP-seq
MIRT1189458	hsa-miR-21	CLIP-seq
MIRT1189459	hsa-miR-302a	CLIP-seq
MIRT1189460	hsa-miR-302b	CLIP-seq
MIRT1189461	hsa-miR-302c	CLIP-seq
MIRT1189462	hsa-miR-302d	CLIP-seq
MIRT1189463	hsa-miR-302e	CLIP-seq
MIRT1189464	hsa-miR-3122	CLIP-seq
MIRT1189465	hsa-miR-3142	CLIP-seq
MIRT1189466	hsa-miR-3202	CLIP-seq
MIRT1189467	hsa-miR-34a	CLIP-seq
MIRT1189468	hsa-miR-34c-5p	CLIP-seq
MIRT1189469	hsa-miR-3609	CLIP-seq
MIRT1189470	hsa-miR-362-5p	CLIP-seq
MIRT1189471	hsa-miR-3688-5p	CLIP-seq
MIRT1189472	hsa-miR-372	CLIP-seq
MIRT1189473	hsa-miR-373	CLIP-seq
MIRT1189474	hsa-miR-3913-5p	CLIP-seq
MIRT1189475	hsa-miR-3919	CLIP-seq
MIRT1189476	hsa-miR-3942-3p	CLIP-seq
MIRT1189477	hsa-miR-4281	CLIP-seq
MIRT1189478	hsa-miR-4319	CLIP-seq
MIRT1189479	hsa-miR-4488	CLIP-seq
MIRT1189480	hsa-miR-4493	CLIP-seq
MIRT1189481	hsa-miR-449a	CLIP-seq
MIRT1189482	hsa-miR-449b	CLIP-seq
MIRT1189483	hsa-miR-4504	CLIP-seq
MIRT1189484	hsa-miR-4505	CLIP-seq
MIRT1189485	hsa-miR-450b-3p	CLIP-seq
MIRT1189486	hsa-miR-4533	CLIP-seq
MIRT1189487	hsa-miR-4640-5p	CLIP-seq
MIRT1189488	hsa-miR-4687-3p	CLIP-seq
MIRT1189489	hsa-miR-4697-5p	CLIP-seq
MIRT1189490	hsa-miR-4726-5p	CLIP-seq
MIRT1189491	hsa-miR-4731-5p	CLIP-seq
MIRT1189492	hsa-miR-4732-3p	CLIP-seq
MIRT1189493	hsa-miR-4756-3p	CLIP-seq
MIRT1189494	hsa-miR-4777-3p	CLIP-seq
MIRT1189495	hsa-miR-4796-3p	CLIP-seq
MIRT1189496	hsa-miR-500b	CLIP-seq
MIRT1189497	hsa-miR-501-5p	CLIP-seq
MIRT1189498	hsa-miR-502-5p	CLIP-seq
MIRT1189499	hsa-miR-512-3p	CLIP-seq
MIRT1189500	hsa-miR-513b	CLIP-seq
MIRT1189501	hsa-miR-519d	CLIP-seq
MIRT1189502	hsa-miR-520a-3p	CLIP-seq
MIRT1189503	hsa-miR-520b	CLIP-seq
MIRT1189504	hsa-miR-520c-3p	CLIP-seq
MIRT1189505	hsa-miR-520d-3p	CLIP-seq
MIRT1189506	hsa-miR-520e	CLIP-seq
MIRT1189507	hsa-miR-542-3p	CLIP-seq
MIRT1189508	hsa-miR-548ah	CLIP-seq
MIRT1189509	hsa-miR-590-5p	CLIP-seq
MIRT1189510	hsa-miR-637	CLIP-seq
MIRT1189511	hsa-miR-642b	CLIP-seq
MIRT1189512	hsa-miR-670	CLIP-seq
MIRT1189513	hsa-miR-708	CLIP-seq
MIRT1189514	hsa-miR-760	CLIP-seq
MIRT1189515	hsa-miR-769-3p	CLIP-seq
MIRT1189516	hsa-miR-875-3p	CLIP-seq
MIRT1189517	hsa-miR-93	CLIP-seq
MIRT1189458	hsa-miR-21	CLIP-seq
MIRT1189518	hsa-miR-219-1-3p	CLIP-seq
MIRT1189519	hsa-miR-323b-3p	CLIP-seq
MIRT1189520	hsa-miR-33a	CLIP-seq
MIRT1189521	hsa-miR-33b	CLIP-seq
MIRT1189522	hsa-miR-4327	CLIP-seq
MIRT1189523	hsa-miR-4424	CLIP-seq
MIRT1189483	hsa-miR-4504	CLIP-seq
MIRT1189524	hsa-miR-451b	CLIP-seq
MIRT1189525	hsa-miR-4524	CLIP-seq
MIRT1189526	hsa-miR-4540	CLIP-seq
MIRT1189527	hsa-miR-4691-5p	CLIP-seq
MIRT1189528	hsa-miR-4731-3p	CLIP-seq
MIRT1189529	hsa-miR-4801	CLIP-seq
MIRT1189507	hsa-miR-542-3p	CLIP-seq
MIRT1189530	hsa-miR-554	CLIP-seq
MIRT1189509	hsa-miR-590-5p	CLIP-seq
MIRT1189511	hsa-miR-642b	CLIP-seq
MIRT1189449	hsa-miR-106a	CLIP-seq
MIRT1189450	hsa-miR-106b	CLIP-seq
MIRT1189531	hsa-miR-1178	CLIP-seq
MIRT1189532	hsa-miR-1207-3p	CLIP-seq
MIRT1189455	hsa-miR-17	CLIP-seq
MIRT1189533	hsa-miR-181a	CLIP-seq
MIRT1189534	hsa-miR-181b	CLIP-seq
MIRT1189535	hsa-miR-181c	CLIP-seq
MIRT1189536	hsa-miR-181d	CLIP-seq
MIRT1189537	hsa-miR-204	CLIP-seq
MIRT1189456	hsa-miR-20a	CLIP-seq
MIRT1189457	hsa-miR-20b	CLIP-seq
MIRT1189458	hsa-miR-21	CLIP-seq
MIRT1189538	hsa-miR-211	CLIP-seq
MIRT1189459	hsa-miR-302a	CLIP-seq
MIRT1189460	hsa-miR-302b	CLIP-seq
MIRT1189461	hsa-miR-302c	CLIP-seq
MIRT1189462	hsa-miR-302d	CLIP-seq
MIRT1189463	hsa-miR-302e	CLIP-seq
MIRT1189539	hsa-miR-3135b	CLIP-seq
MIRT1189540	hsa-miR-3175	CLIP-seq
MIRT1189541	hsa-miR-3184	CLIP-seq
MIRT1189542	hsa-miR-329	CLIP-seq
MIRT1189469	hsa-miR-3609	CLIP-seq
MIRT1189543	hsa-miR-3620	CLIP-seq
MIRT1189544	hsa-miR-3652	CLIP-seq
MIRT1189545	hsa-miR-3674	CLIP-seq
MIRT1189472	hsa-miR-372	CLIP-seq
MIRT1189473	hsa-miR-373	CLIP-seq
MIRT1189475	hsa-miR-3919	CLIP-seq
MIRT1189546	hsa-miR-3922-5p	CLIP-seq
MIRT1189476	hsa-miR-3942-3p	CLIP-seq
MIRT1189547	hsa-miR-4262	CLIP-seq
MIRT1189548	hsa-miR-4277	CLIP-seq
MIRT1189549	hsa-miR-4278	CLIP-seq
MIRT1189550	hsa-miR-4287	CLIP-seq
MIRT1189551	hsa-miR-4320	CLIP-seq
MIRT1189552	hsa-miR-4430	CLIP-seq
MIRT1189553	hsa-miR-4434	CLIP-seq
MIRT1189554	hsa-miR-4436a	CLIP-seq
MIRT1189555	hsa-miR-4476	CLIP-seq
MIRT1189483	hsa-miR-4504	CLIP-seq
MIRT1189556	hsa-miR-4514	CLIP-seq
MIRT1189557	hsa-miR-4516	CLIP-seq
MIRT1189558	hsa-miR-4520a-3p	CLIP-seq
MIRT1189559	hsa-miR-4531	CLIP-seq
MIRT1189560	hsa-miR-4638-3p	CLIP-seq
MIRT1189561	hsa-miR-4645-5p	CLIP-seq
MIRT1189562	hsa-miR-4673	CLIP-seq
MIRT1189563	hsa-miR-4680-3p	CLIP-seq
MIRT1189564	hsa-miR-4685-3p	CLIP-seq
MIRT1189565	hsa-miR-4692	CLIP-seq
MIRT1189566	hsa-miR-4693-3p	CLIP-seq
MIRT1189567	hsa-miR-4700-3p	CLIP-seq
MIRT1189568	hsa-miR-4716-3p	CLIP-seq
MIRT1189493	hsa-miR-4756-3p	CLIP-seq
MIRT1189495	hsa-miR-4796-3p	CLIP-seq
MIRT1189569	hsa-miR-4803	CLIP-seq
MIRT1189570	hsa-miR-483-5p	CLIP-seq
MIRT1189571	hsa-miR-501-3p	CLIP-seq
MIRT1189572	hsa-miR-502-3p	CLIP-seq
MIRT1189499	hsa-miR-512-3p	CLIP-seq
MIRT1189500	hsa-miR-513b	CLIP-seq
MIRT1189501	hsa-miR-519d	CLIP-seq
MIRT1189502	hsa-miR-520a-3p	CLIP-seq
MIRT1189503	hsa-miR-520b	CLIP-seq
MIRT1189504	hsa-miR-520c-3p	CLIP-seq
MIRT1189505	hsa-miR-520d-3p	CLIP-seq
MIRT1189506	hsa-miR-520e	CLIP-seq
MIRT1189507	hsa-miR-542-3p	CLIP-seq
MIRT1189573	hsa-miR-543	CLIP-seq
MIRT1189574	hsa-miR-548a-3p	CLIP-seq
MIRT1189508	hsa-miR-548ah	CLIP-seq
MIRT1189575	hsa-miR-548e	CLIP-seq
MIRT1189576	hsa-miR-548f	CLIP-seq
MIRT1189577	hsa-miR-566	CLIP-seq
MIRT1189509	hsa-miR-590-5p	CLIP-seq
MIRT1189511	hsa-miR-642b	CLIP-seq
MIRT1189513	hsa-miR-708	CLIP-seq
MIRT1189578	hsa-miR-767-5p	CLIP-seq
MIRT1189517	hsa-miR-93	CLIP-seq
MIRT1189579	hsa-miR-940	CLIP-seq
MIRT1189500	hsa-miR-513b	CLIP-seq
MIRT1189513	hsa-miR-708	CLIP-seq
MIRT1189500	hsa-miR-513b	CLIP-seq
MIRT1189513	hsa-miR-708	CLIP-seq
MIRT1922883	hsa-miR-338-3p	CLIP-seq
MIRT1922884	hsa-miR-4530	CLIP-seq
MIRT1189527	hsa-miR-4691-5p	CLIP-seq
MIRT1922885	hsa-miR-4736	CLIP-seq
MIRT1922886	hsa-miR-486-3p	CLIP-seq
MIRT1922887	hsa-miR-766	CLIP-seq
MIRT1189542	hsa-miR-329	CLIP-seq
MIRT2054837	hsa-miR-1269	CLIP-seq
MIRT2054838	hsa-miR-1269b	CLIP-seq
MIRT2054839	hsa-miR-4529-3p	CLIP-seq
MIRT1189542	hsa-miR-329	CLIP-seq
MIRT1189542	hsa-miR-329	CLIP-seq
MIRT1189467	hsa-miR-34a	CLIP-seq
MIRT1189468	hsa-miR-34c-5p	CLIP-seq
MIRT1189546	hsa-miR-3922-5p	CLIP-seq
MIRT2283904	hsa-miR-3941	CLIP-seq
MIRT1189481	hsa-miR-449a	CLIP-seq
MIRT1189482	hsa-miR-449b	CLIP-seq
MIRT2283905	hsa-miR-603	CLIP-seq
MIRT1189458	hsa-miR-21	CLIP-seq
MIRT1189543	hsa-miR-3620	CLIP-seq
MIRT1189555	hsa-miR-4476	CLIP-seq
MIRT1189483	hsa-miR-4504	CLIP-seq
MIRT1189569	hsa-miR-4803	CLIP-seq
MIRT1189571	hsa-miR-501-3p	CLIP-seq
MIRT1189572	hsa-miR-502-3p	CLIP-seq
MIRT1189500	hsa-miR-513b	CLIP-seq
MIRT1189507	hsa-miR-542-3p	CLIP-seq
MIRT1189509	hsa-miR-590-5p	CLIP-seq
MIRT1189511	hsa-miR-642b	CLIP-seq
MIRT1189513	hsa-miR-708	CLIP-seq
MIRT1189578	hsa-miR-767-5p	CLIP-seq
MIRT1189574	hsa-miR-548a-3p	CLIP-seq
MIRT1189575	hsa-miR-548e	CLIP-seq
MIRT1189576	hsa-miR-548f	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003062	Process	Regulation of heart rate by chemical signal	IMP	19247217
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005634	Component	Nucleus	ISS	24665357
GO:0005739	Component	Mitochondrion	ISS	19800018
GO:0005829	Component	Cytosol	ISS	24665357
GO:0005901	Component	Caveola	ISS	19800018
GO:0010628	Process	Positive regulation of gene expression	ISS	18337493
GO:0010750	Process	Positive regulation of nitric oxide mediated signal transduction	ISS	18337493
GO:0030018	Component	Z disc	ISS	19800018
GO:0030315	Component	T-tubule	ISS	24665357
GO:0031965	Component	Nuclear membrane	ISS	24665357
GO:0033017	Component	Sarcoplasmic reticulum membrane	ISS	19800018
GO:0042383	Component	Sarcolemma	ISS	18337493
GO:0045428	Process	Regulation of nitric oxide biosynthetic process	NAS	20431962
GO:0045429	Process	Positive regulation of nitric oxide biosynthetic process	ISS	18337493
GO:0048471	Component	Perinuclear region of cytoplasm	ISS	18337493
GO:0050998	Function	Nitric-oxide synthase binding	IBA	21873635
GO:0050998	Function	Nitric-oxide synthase binding	ISS	9459447
GO:0050999	Process	Regulation of nitric-oxide synthase activity	NAS	20431962
GO:0051000	Process	Positive regulation of nitric-oxide synthase activity	ISS	18337493
GO:0060307	Process	Regulation of ventricular cardiac muscle cell membrane repolarization	IMP	19247217
GO:0060307	Process	Regulation of ventricular cardiac muscle cell membrane repolarization	ISS	18337493
GO:0098901	Process	Regulation of cardiac muscle cell action potential	ISS	18337493
GO:0098901	Process	Regulation of cardiac muscle cell action potential	TAS	24665357
GO:0098974	Process	Postsynaptic actin cytoskeleton organization	IDA	26869880
GO:0098974	Process	Postsynaptic actin cytoskeleton organization	IMP	26869880
GO:0098978	Component	Glutamatergic synapse	IDA	26869880
GO:0098978	Component	Glutamatergic synapse	IMP	26869880
GO:1901381	Process	Positive regulation of potassium ion transmembrane transport	ISS	18337493
GO:1901841	Process	Regulation of high voltage-gated calcium channel activity	ISS	18337493, 24665357
GO:1902261	Process	Positive regulation of delayed rectifier potassium channel activity	ISS	18337493
GO:1902514	Process	Regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	ISS	18337493
GO:1902514	Process	Regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	TAS	24665357
GO:1902937	Component	Inward rectifier potassium channel complex	ISS	24665357
GO:1903762	Process	Positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	ISS	18337493
GO:1990454	Component	L-type voltage-gated calcium channel complex	ISS	24665357
GO:2000170	Process	Positive regulation of peptidyl-cysteine S-nitrosylation	ISS	24665357

Other IDs

• MIM: 605551
• HGNC: 16859
• e!Ensembl: ENSG00000198929

Protein

• UniProt ID: O75052
• Protein name: Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein)
• Protein function: Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an in
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00640	PID	32 → 175	Phosphotyrosine interaction domain (PTB/PID)	Domain

• Sequence:

  MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY
  EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS
  HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA
  DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL
  DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL
  QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE
  LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG
  RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS
  QEELPRLLNVLQRQELGDGLDDEIAV

• Sequence length: 506

Pathways

KEGG:

Circadian entrainment

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Dysautonomia	Dysautonomia	rs111033171, rs137853022, rs28939712, rs754348901, rs749052963, rs1057517169, rs1057516865, rs763445509, rs767527819, rs781333644, rs1239081703, rs1554696574, rs539544212, rs1201626345, rs774890086, rs1554703061, rs1554703613, rs1319053366, rs1554703851, rs868073099, rs926177767, rs376078668, rs1554695299, rs1554696648, rs1554696934, rs1554699327, rs1554691572, rs1554695846, rs1554697001, rs770668926, rs1554698037, rs759412460, rs1554702142, rs765572951, rs1554702880, rs1554703831, rs760774999, rs1554696650, rs757972943, rs1554703874, rs1554703907, rs571348995
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	24220657, 20638248, 23212062

Unknown
Disease name	Disease term	dbSNP ID	References
Romano-ward syndrome	Romano-Ward Syndrome		20538168, 19822806
Torsades de pointes	Torsades de Pointes	rs36210421, rs36210419, rs36210415, rs36210416, rs36210420