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VGLL4 (vestigial like family member 4)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9686
Gene nameGene Name - the full gene name approved by the HGNC.
Vestigial like family member 4
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
VGLL4
SynonymsGene synonyms aliases
VGL-4
ChromosomeChromosome number
3
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p25.3-p25.2
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019746 hsa-miR-375 Microarray 20215506
MIRT052473 hsa-let-7a-5p CLASH 23622248
MIRT051646 hsa-let-7e-5p CLASH 23622248
MIRT438320 hsa-miR-222-3p ChIP-seq, Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot 26045994
MIRT438320 hsa-miR-222-3p ChIP-seq, Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot 26045994
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001223 Function Transcription coactivator binding IBA 21873635
GO:0005515 Function Protein binding IPI 21044950, 24525233, 28051067, 32296183
GO:0005634 Component Nucleus ISS
GO:0030178 Process Negative regulation of Wnt signaling pathway IDA 28051067
GO:0030308 Process Negative regulation of cell growth IDA 28051067
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q14135
Protein name Transcription cofactor vestigial-like protein 4 (Vgl-4)
Protein function May act as a specific coactivator for the mammalian TEFs.
PDB 8YTF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15245 VGLL4
4 224
Transcription cofactor vestigial-like protein 4
Family
Sequence
Sequence length 290
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Chronic obstructive pulmonary disease Chronic Obstructive Airway Disease rs2227956, rs1008438, rs1043618, rs562047, rs1061581, rs2763979, rs6457452, rs13147758, rs1828591, rs13118928 30804561
Unknown
Disease name Disease term dbSNP ID References
Alopecia Alopecia 28196072

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