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FEZ2 (fasciculation and elongation protein zeta 2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9637
Gene nameGene Name - the full gene name approved by the HGNC.
Fasciculation and elongation protein zeta 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
FEZ2
SynonymsGene synonyms aliases
HUM3CL
ChromosomeChromosome number
2
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2p22.2
SummarySummary of gene provided in NCBI Entrez Gene.
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq, Jul
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT528032 hsa-miR-4282 PAR-CLIP 22012620
MIRT528031 hsa-miR-634 PAR-CLIP 22012620
MIRT528030 hsa-miR-302a-5p PAR-CLIP 22012620
MIRT528029 hsa-miR-3682-5p PAR-CLIP 22012620
MIRT528027 hsa-miR-4477a PAR-CLIP 22012620
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 14690447, 24705354, 32296183, 32814053
GO:0005737 Component Cytoplasm IBA 21873635
GO:0007165 Process Signal transduction TAS 9096408
GO:0007399 Process Nervous system development TAS 9096408
GO:0007411 Process Axon guidance TAS 9096408
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9UHY8
Protein name Fasciculation and elongation protein zeta-2 (Zygin II) (Zygin-2)
Protein function Involved in axonal outgrowth and fasciculation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07763 FEZ
51 286
FEZ-like protein
Family
Sequence
Sequence length 353
Interactions View interactions
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Myocardial ischemia Myocardial Ischemia 16214533

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