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IER2 (immediate early response 2)

Gene

9592

Immediate early response 2

IER2

CHX1, ETR101

19p13.13

Show/Hide all(330)

miRTarBase ID	miRNA	Experiments	Reference
MIRT040855	hsa-miR-18a-3p	CLASH	23622248
MIRT399356	hsa-miR-548ae-3p	PAR-CLIP	23592263
MIRT399357	hsa-miR-548ah-3p	PAR-CLIP	23592263
MIRT399358	hsa-miR-548aj-3p	PAR-CLIP	23592263
MIRT399359	hsa-miR-548am-3p	PAR-CLIP	23592263
MIRT399360	hsa-miR-548aq-3p	PAR-CLIP	23592263
MIRT399350	hsa-miR-548j-3p	PAR-CLIP	23592263
MIRT399353	hsa-miR-548x-3p	PAR-CLIP	23592263
MIRT399362	hsa-miR-5582-3p	PAR-CLIP	23592263
MIRT484238	hsa-miR-5700	PAR-CLIP	23592263
MIRT235001	hsa-miR-8066	PAR-CLIP	23592263
MIRT484237	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT484235	hsa-miR-5694	PAR-CLIP	23592263
MIRT484236	hsa-miR-1245b-3p	PAR-CLIP	23592263
MIRT484234	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT484233	hsa-miR-1910-5p	PAR-CLIP	23592263
MIRT484232	hsa-miR-539-5p	PAR-CLIP	23592263
MIRT234999	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT150354	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT150357	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT150355	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT150358	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT150354	hsa-miR-15a-5p	PAR-CLIP	26701625
MIRT150357	hsa-miR-15b-5p	PAR-CLIP	26701625
MIRT150355	hsa-miR-16-5p	PAR-CLIP	26701625
MIRT150358	hsa-miR-195-5p	PAR-CLIP	26701625
MIRT399356	hsa-miR-548ae-3p	PAR-CLIP	23592263
MIRT399357	hsa-miR-548ah-3p	PAR-CLIP	23592263
MIRT399358	hsa-miR-548aj-3p	PAR-CLIP	23592263
MIRT399359	hsa-miR-548am-3p	PAR-CLIP	23592263
MIRT399360	hsa-miR-548aq-3p	PAR-CLIP	23592263
MIRT399350	hsa-miR-548j-3p	PAR-CLIP	23592263
MIRT399353	hsa-miR-548x-3p	PAR-CLIP	23592263
MIRT399362	hsa-miR-5582-3p	PAR-CLIP	23592263
MIRT484238	hsa-miR-5700	PAR-CLIP	23592263
MIRT235001	hsa-miR-8066	PAR-CLIP	23592263
MIRT484237	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT484235	hsa-miR-5694	PAR-CLIP	23592263
MIRT484236	hsa-miR-1245b-3p	PAR-CLIP	23592263
MIRT484234	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT484233	hsa-miR-1910-5p	PAR-CLIP	23592263
MIRT484232	hsa-miR-539-5p	PAR-CLIP	23592263
MIRT234999	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT1059722	hsa-miR-101	CLIP-seq
MIRT1059723	hsa-miR-1224-3p	CLIP-seq
MIRT1059724	hsa-miR-125a-5p	CLIP-seq
MIRT1059725	hsa-miR-125b	CLIP-seq
MIRT1059726	hsa-miR-1260	CLIP-seq
MIRT1059727	hsa-miR-1260b	CLIP-seq
MIRT1059728	hsa-miR-1265	CLIP-seq
MIRT1059729	hsa-miR-1280	CLIP-seq
MIRT1059730	hsa-miR-1307	CLIP-seq
MIRT1059731	hsa-miR-1321	CLIP-seq
MIRT1059732	hsa-miR-139-3p	CLIP-seq
MIRT1059733	hsa-miR-15a	CLIP-seq
MIRT1059734	hsa-miR-15b	CLIP-seq
MIRT1059735	hsa-miR-16	CLIP-seq
MIRT1059736	hsa-miR-18a	CLIP-seq
MIRT1059737	hsa-miR-18b	CLIP-seq
MIRT1059738	hsa-miR-1910	CLIP-seq
MIRT1059739	hsa-miR-1915	CLIP-seq
MIRT1059740	hsa-miR-195	CLIP-seq
MIRT1059741	hsa-miR-219-5p	CLIP-seq
MIRT1059742	hsa-miR-2355-5p	CLIP-seq
MIRT1059743	hsa-miR-2467-3p	CLIP-seq
MIRT1059744	hsa-miR-30a	CLIP-seq
MIRT1059745	hsa-miR-30b	CLIP-seq
MIRT1059746	hsa-miR-30c	CLIP-seq
MIRT1059747	hsa-miR-30d	CLIP-seq
MIRT1059748	hsa-miR-30e	CLIP-seq
MIRT1059749	hsa-miR-31	CLIP-seq
MIRT1059750	hsa-miR-3126-5p	CLIP-seq
MIRT1059751	hsa-miR-3128	CLIP-seq
MIRT1059752	hsa-miR-3150b-3p	CLIP-seq
MIRT1059753	hsa-miR-3181	CLIP-seq
MIRT1059754	hsa-miR-3184	CLIP-seq
MIRT1059755	hsa-miR-328	CLIP-seq
MIRT1059756	hsa-miR-330-3p	CLIP-seq
MIRT1059757	hsa-miR-3646	CLIP-seq
MIRT1059758	hsa-miR-3657	CLIP-seq
MIRT1059759	hsa-miR-3662	CLIP-seq
MIRT1059760	hsa-miR-3678-3p	CLIP-seq
MIRT1059761	hsa-miR-423-5p	CLIP-seq
MIRT1059762	hsa-miR-424	CLIP-seq
MIRT1059763	hsa-miR-4292	CLIP-seq
MIRT1059764	hsa-miR-4308	CLIP-seq
MIRT1059765	hsa-miR-4319	CLIP-seq
MIRT1059766	hsa-miR-4419a	CLIP-seq
MIRT1059767	hsa-miR-4445	CLIP-seq
MIRT1059768	hsa-miR-4510	CLIP-seq
MIRT1059769	hsa-miR-4527	CLIP-seq
MIRT1059770	hsa-miR-4638-5p	CLIP-seq
MIRT1059771	hsa-miR-4640-5p	CLIP-seq
MIRT1059772	hsa-miR-4649-3p	CLIP-seq
MIRT1059773	hsa-miR-4669	CLIP-seq
MIRT1059774	hsa-miR-4683	CLIP-seq
MIRT1059775	hsa-miR-4688	CLIP-seq
MIRT1059776	hsa-miR-4689	CLIP-seq
MIRT1059777	hsa-miR-4690-3p	CLIP-seq
MIRT1059778	hsa-miR-4698	CLIP-seq
MIRT1059779	hsa-miR-4708-3p	CLIP-seq
MIRT1059780	hsa-miR-4711-3p	CLIP-seq
MIRT1059781	hsa-miR-4725-5p	CLIP-seq
MIRT1059782	hsa-miR-4726-3p	CLIP-seq
MIRT1059783	hsa-miR-4726-5p	CLIP-seq
MIRT1059784	hsa-miR-4728-5p	CLIP-seq
MIRT1059785	hsa-miR-4735-3p	CLIP-seq
MIRT1059786	hsa-miR-4739	CLIP-seq
MIRT1059787	hsa-miR-4756-5p	CLIP-seq
MIRT1059788	hsa-miR-4758-3p	CLIP-seq
MIRT1059789	hsa-miR-4782-3p	CLIP-seq
MIRT1059790	hsa-miR-4784	CLIP-seq
MIRT1059791	hsa-miR-488	CLIP-seq
MIRT1059792	hsa-miR-490-3p	CLIP-seq
MIRT1059793	hsa-miR-497	CLIP-seq
MIRT1059794	hsa-miR-504	CLIP-seq
MIRT1059795	hsa-miR-508-3p	CLIP-seq
MIRT1059796	hsa-miR-510	CLIP-seq
MIRT1059797	hsa-miR-532-3p	CLIP-seq
MIRT1059798	hsa-miR-544b	CLIP-seq
MIRT1059799	hsa-miR-548ag	CLIP-seq
MIRT1059800	hsa-miR-548ai	CLIP-seq
MIRT1059801	hsa-miR-592	CLIP-seq
MIRT1059802	hsa-miR-599	CLIP-seq
MIRT1059803	hsa-miR-873	CLIP-seq
MIRT1059723	hsa-miR-1224-3p	CLIP-seq
MIRT1059726	hsa-miR-1260	CLIP-seq
MIRT1059727	hsa-miR-1260b	CLIP-seq
MIRT1059728	hsa-miR-1265	CLIP-seq
MIRT1059729	hsa-miR-1280	CLIP-seq
MIRT2013919	hsa-miR-1285	CLIP-seq
MIRT1059730	hsa-miR-1307	CLIP-seq
MIRT1059732	hsa-miR-139-3p	CLIP-seq
MIRT1059733	hsa-miR-15a	CLIP-seq
MIRT1059734	hsa-miR-15b	CLIP-seq
MIRT1059735	hsa-miR-16	CLIP-seq
MIRT1059736	hsa-miR-18a	CLIP-seq
MIRT1059737	hsa-miR-18b	CLIP-seq
MIRT1059738	hsa-miR-1910	CLIP-seq
MIRT1059740	hsa-miR-195	CLIP-seq
MIRT1059741	hsa-miR-219-5p	CLIP-seq
MIRT1059742	hsa-miR-2355-5p	CLIP-seq
MIRT1059743	hsa-miR-2467-3p	CLIP-seq
MIRT1059749	hsa-miR-31	CLIP-seq
MIRT1059750	hsa-miR-3126-5p	CLIP-seq
MIRT2013920	hsa-miR-3136-3p	CLIP-seq
MIRT2013921	hsa-miR-3187-5p	CLIP-seq
MIRT1059755	hsa-miR-328	CLIP-seq
MIRT1059758	hsa-miR-3657	CLIP-seq
MIRT1059760	hsa-miR-3678-3p	CLIP-seq
MIRT1059762	hsa-miR-424	CLIP-seq
MIRT1059766	hsa-miR-4419a	CLIP-seq
MIRT1059767	hsa-miR-4445	CLIP-seq
MIRT1059768	hsa-miR-4510	CLIP-seq
MIRT1059770	hsa-miR-4638-5p	CLIP-seq
MIRT1059772	hsa-miR-4649-3p	CLIP-seq
MIRT1059773	hsa-miR-4669	CLIP-seq
MIRT2013922	hsa-miR-4707-5p	CLIP-seq
MIRT1059780	hsa-miR-4711-3p	CLIP-seq
MIRT1059785	hsa-miR-4735-3p	CLIP-seq
MIRT1059788	hsa-miR-4758-3p	CLIP-seq
MIRT1059789	hsa-miR-4782-3p	CLIP-seq
MIRT2013923	hsa-miR-495	CLIP-seq
MIRT1059793	hsa-miR-497	CLIP-seq
MIRT1059795	hsa-miR-508-3p	CLIP-seq
MIRT1059796	hsa-miR-510	CLIP-seq
MIRT2013924	hsa-miR-524-3p	CLIP-seq
MIRT2013925	hsa-miR-525-3p	CLIP-seq
MIRT1059797	hsa-miR-532-3p	CLIP-seq
MIRT2013926	hsa-miR-539	CLIP-seq
MIRT2013927	hsa-miR-548ac	CLIP-seq
MIRT2013928	hsa-miR-548ae	CLIP-seq
MIRT2013929	hsa-miR-548aj	CLIP-seq
MIRT2013930	hsa-miR-548am	CLIP-seq
MIRT2013931	hsa-miR-548d-3p	CLIP-seq
MIRT2013932	hsa-miR-548x	CLIP-seq
MIRT2013933	hsa-miR-548z	CLIP-seq
MIRT2013934	hsa-miR-580	CLIP-seq
MIRT1059801	hsa-miR-592	CLIP-seq
MIRT1059802	hsa-miR-599	CLIP-seq
MIRT2013935	hsa-miR-612	CLIP-seq
MIRT1059803	hsa-miR-873	CLIP-seq
MIRT1059722	hsa-miR-101	CLIP-seq
MIRT1059723	hsa-miR-1224-3p	CLIP-seq
MIRT2246076	hsa-miR-1226	CLIP-seq
MIRT2246077	hsa-miR-1250	CLIP-seq
MIRT1059726	hsa-miR-1260	CLIP-seq
MIRT1059727	hsa-miR-1260b	CLIP-seq
MIRT2246078	hsa-miR-1273	CLIP-seq
MIRT1059729	hsa-miR-1280	CLIP-seq
MIRT2013919	hsa-miR-1285	CLIP-seq
MIRT2246079	hsa-miR-1292	CLIP-seq
MIRT1059730	hsa-miR-1307	CLIP-seq
MIRT1059731	hsa-miR-1321	CLIP-seq
MIRT1059732	hsa-miR-139-3p	CLIP-seq
MIRT1059733	hsa-miR-15a	CLIP-seq
MIRT1059734	hsa-miR-15b	CLIP-seq
MIRT1059735	hsa-miR-16	CLIP-seq
MIRT1059736	hsa-miR-18a	CLIP-seq
MIRT1059737	hsa-miR-18b	CLIP-seq
MIRT2246080	hsa-miR-1913	CLIP-seq
MIRT1059739	hsa-miR-1915	CLIP-seq
MIRT1059740	hsa-miR-195	CLIP-seq
MIRT2246081	hsa-miR-197	CLIP-seq
MIRT1059741	hsa-miR-219-5p	CLIP-seq
MIRT2246082	hsa-miR-24	CLIP-seq
MIRT1059743	hsa-miR-2467-3p	CLIP-seq
MIRT1059750	hsa-miR-3126-5p	CLIP-seq
MIRT2013920	hsa-miR-3136-3p	CLIP-seq
MIRT1059754	hsa-miR-3184	CLIP-seq
MIRT2013921	hsa-miR-3187-5p	CLIP-seq
MIRT2246083	hsa-miR-3189-5p	CLIP-seq
MIRT2246084	hsa-miR-3200-5p	CLIP-seq
MIRT2246085	hsa-miR-324-3p	CLIP-seq
MIRT2246086	hsa-miR-326	CLIP-seq
MIRT1059755	hsa-miR-328	CLIP-seq
MIRT2246087	hsa-miR-330-5p	CLIP-seq
MIRT2246088	hsa-miR-337-3p	CLIP-seq
MIRT1059757	hsa-miR-3646	CLIP-seq
MIRT2246089	hsa-miR-3660	CLIP-seq
MIRT1059759	hsa-miR-3662	CLIP-seq
MIRT1059760	hsa-miR-3678-3p	CLIP-seq
MIRT2246090	hsa-miR-3685	CLIP-seq
MIRT2246091	hsa-miR-378g	CLIP-seq
MIRT2246092	hsa-miR-384	CLIP-seq
MIRT1059761	hsa-miR-423-5p	CLIP-seq
MIRT1059762	hsa-miR-424	CLIP-seq
MIRT2246093	hsa-miR-4286	CLIP-seq
MIRT1059766	hsa-miR-4419a	CLIP-seq
MIRT1059767	hsa-miR-4445	CLIP-seq
MIRT2246094	hsa-miR-4471	CLIP-seq
MIRT2246095	hsa-miR-4486	CLIP-seq
MIRT2246096	hsa-miR-4494	CLIP-seq
MIRT1059768	hsa-miR-4510	CLIP-seq
MIRT2246097	hsa-miR-4526	CLIP-seq
MIRT1059770	hsa-miR-4638-5p	CLIP-seq
MIRT1059771	hsa-miR-4640-5p	CLIP-seq
MIRT2246098	hsa-miR-4646-5p	CLIP-seq
MIRT1059772	hsa-miR-4649-3p	CLIP-seq
MIRT1059773	hsa-miR-4669	CLIP-seq
MIRT1059775	hsa-miR-4688	CLIP-seq
MIRT1059777	hsa-miR-4690-3p	CLIP-seq
MIRT1059778	hsa-miR-4698	CLIP-seq
MIRT2013922	hsa-miR-4707-5p	CLIP-seq
MIRT1059779	hsa-miR-4708-3p	CLIP-seq
MIRT1059780	hsa-miR-4711-3p	CLIP-seq
MIRT1059782	hsa-miR-4726-3p	CLIP-seq
MIRT1059783	hsa-miR-4726-5p	CLIP-seq
MIRT1059784	hsa-miR-4728-5p	CLIP-seq
MIRT2246099	hsa-miR-4733-3p	CLIP-seq
MIRT1059785	hsa-miR-4735-3p	CLIP-seq
MIRT1059786	hsa-miR-4739	CLIP-seq
MIRT1059787	hsa-miR-4756-5p	CLIP-seq
MIRT1059788	hsa-miR-4758-3p	CLIP-seq
MIRT2246100	hsa-miR-4763-5p	CLIP-seq
MIRT1059789	hsa-miR-4782-3p	CLIP-seq
MIRT1059791	hsa-miR-488	CLIP-seq
MIRT1059792	hsa-miR-490-3p	CLIP-seq
MIRT1059793	hsa-miR-497	CLIP-seq
MIRT2246101	hsa-miR-499a-5p	CLIP-seq
MIRT1059795	hsa-miR-508-3p	CLIP-seq
MIRT2246102	hsa-miR-5096	CLIP-seq
MIRT1059796	hsa-miR-510	CLIP-seq
MIRT1059797	hsa-miR-532-3p	CLIP-seq
MIRT2013927	hsa-miR-548ac	CLIP-seq
MIRT2013931	hsa-miR-548d-3p	CLIP-seq
MIRT2013933	hsa-miR-548z	CLIP-seq
MIRT2013935	hsa-miR-612	CLIP-seq
MIRT1059803	hsa-miR-873	CLIP-seq
MIRT2246103	hsa-miR-891a	CLIP-seq
MIRT2013919	hsa-miR-1285	CLIP-seq
MIRT2246079	hsa-miR-1292	CLIP-seq
MIRT1059730	hsa-miR-1307	CLIP-seq
MIRT1059731	hsa-miR-1321	CLIP-seq
MIRT1059741	hsa-miR-219-5p	CLIP-seq
MIRT1059750	hsa-miR-3126-5p	CLIP-seq
MIRT1059754	hsa-miR-3184	CLIP-seq
MIRT2013921	hsa-miR-3187-5p	CLIP-seq
MIRT1059758	hsa-miR-3657	CLIP-seq
MIRT1059761	hsa-miR-423-5p	CLIP-seq
MIRT1059766	hsa-miR-4419a	CLIP-seq
MIRT1059767	hsa-miR-4445	CLIP-seq
MIRT2246094	hsa-miR-4471	CLIP-seq
MIRT1059768	hsa-miR-4510	CLIP-seq
MIRT1059770	hsa-miR-4638-5p	CLIP-seq
MIRT2246098	hsa-miR-4646-5p	CLIP-seq
MIRT1059772	hsa-miR-4649-3p	CLIP-seq
MIRT1059773	hsa-miR-4669	CLIP-seq
MIRT1059775	hsa-miR-4688	CLIP-seq
MIRT1059780	hsa-miR-4711-3p	CLIP-seq
MIRT1059784	hsa-miR-4728-5p	CLIP-seq
MIRT1059786	hsa-miR-4739	CLIP-seq
MIRT1059787	hsa-miR-4756-5p	CLIP-seq
MIRT1059789	hsa-miR-4782-3p	CLIP-seq
MIRT1059792	hsa-miR-490-3p	CLIP-seq
MIRT1059795	hsa-miR-508-3p	CLIP-seq
MIRT1059801	hsa-miR-592	CLIP-seq
MIRT1059802	hsa-miR-599	CLIP-seq
MIRT2013935	hsa-miR-612	CLIP-seq
MIRT1059803	hsa-miR-873	CLIP-seq
MIRT2013919	hsa-miR-1285	CLIP-seq
MIRT2246079	hsa-miR-1292	CLIP-seq
MIRT1059730	hsa-miR-1307	CLIP-seq
MIRT1059731	hsa-miR-1321	CLIP-seq
MIRT1059741	hsa-miR-219-5p	CLIP-seq
MIRT1059750	hsa-miR-3126-5p	CLIP-seq
MIRT1059754	hsa-miR-3184	CLIP-seq
MIRT2013921	hsa-miR-3187-5p	CLIP-seq
MIRT1059758	hsa-miR-3657	CLIP-seq
MIRT1059761	hsa-miR-423-5p	CLIP-seq
MIRT1059766	hsa-miR-4419a	CLIP-seq
MIRT1059767	hsa-miR-4445	CLIP-seq
MIRT2246094	hsa-miR-4471	CLIP-seq
MIRT1059768	hsa-miR-4510	CLIP-seq
MIRT1059770	hsa-miR-4638-5p	CLIP-seq
MIRT2246098	hsa-miR-4646-5p	CLIP-seq
MIRT1059772	hsa-miR-4649-3p	CLIP-seq
MIRT1059773	hsa-miR-4669	CLIP-seq
MIRT1059775	hsa-miR-4688	CLIP-seq
MIRT1059780	hsa-miR-4711-3p	CLIP-seq
MIRT1059784	hsa-miR-4728-5p	CLIP-seq
MIRT1059786	hsa-miR-4739	CLIP-seq
MIRT1059787	hsa-miR-4756-5p	CLIP-seq
MIRT1059789	hsa-miR-4782-3p	CLIP-seq
MIRT1059792	hsa-miR-490-3p	CLIP-seq
MIRT1059795	hsa-miR-508-3p	CLIP-seq
MIRT1059801	hsa-miR-592	CLIP-seq
MIRT1059802	hsa-miR-599	CLIP-seq
MIRT2013935	hsa-miR-612	CLIP-seq
MIRT1059803	hsa-miR-873	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IDA	22120713
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	22120713
GO:0030182	Process	Neuron differentiation	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	19584537
GO:0048870	Process	Cell motility	IMP	22120713
GO:0071774	Process	Response to fibroblast growth factor	ISS

MIM	HGNC	e!Ensembl
620036	28871	ENSG00000160888

Protein

UniProt ID

Q9BTL4

Protein name

Immediate early response gene 2 protein (Protein ETR101)

Protein function

DNA-binding protein that seems to act as a transcription factor (PubMed:19584537). Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (By

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05760	IER	1 → 203	Immediate early response protein (IER)	Family

Sequence

MEVQKEAQRIMTLSVWKMYHSRMQRGGLRLHRSLQLSLVMRSARELYLSAKVEALEPEVS
LPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPRPAKVSR
KRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAEGAFPNLARVLQR
RFSGLLNCSPAAPPTAPPACEAKPACRPADSMLNVLVRAVVAF

Sequence length

223

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Lung cancer	Malignant neoplasm of lung	rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135	27935865

Show/Hide Unknown Diseases (1)

Unknown
Disease name	Disease term	dbSNP ID	References
Lung neoplasms	Lung Neoplasms		27935865

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