ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif 1)

Gene

• Entrez ID: 9510
• Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 1
• Gene symbol: ADAMTS1
• Synonyms: C3-C5, METH1
• Chromosome: 21
• Chromosome location: 21q21.3
• Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022469	hsa-miR-124-3p	Microarray	18668037
MIRT029236	hsa-miR-26b-5p	Microarray	19088304
MIRT049047	hsa-miR-92a-3p	CLASH	23622248
MIRT040291	hsa-miR-615-3p	CLASH	23622248
MIRT036972	hsa-miR-877-3p	CLASH	23622248
MIRT036972	hsa-miR-877-3p	CLASH	23622248
MIRT724228	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT724227	hsa-miR-4793-5p	HITS-CLIP	19536157
MIRT724226	hsa-miR-5193	HITS-CLIP	19536157
MIRT724225	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT724224	hsa-miR-581	HITS-CLIP	19536157
MIRT724223	hsa-miR-6854-3p	HITS-CLIP	19536157
MIRT724222	hsa-miR-1180-3p	HITS-CLIP	19536157
MIRT724228	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT724227	hsa-miR-4793-5p	HITS-CLIP	19536157
MIRT724226	hsa-miR-5193	HITS-CLIP	19536157
MIRT724225	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT724224	hsa-miR-581	HITS-CLIP	19536157
MIRT724223	hsa-miR-6854-3p	HITS-CLIP	19536157
MIRT724222	hsa-miR-1180-3p	HITS-CLIP	19536157
MIRT766326	hsa-let-7a	CLIP-seq
MIRT766327	hsa-let-7b	CLIP-seq
MIRT766328	hsa-let-7c	CLIP-seq
MIRT766329	hsa-let-7d	CLIP-seq
MIRT766330	hsa-let-7e	CLIP-seq
MIRT766331	hsa-let-7f	CLIP-seq
MIRT766332	hsa-let-7g	CLIP-seq
MIRT766333	hsa-let-7i	CLIP-seq
MIRT766334	hsa-miR-1229	CLIP-seq
MIRT766335	hsa-miR-1294	CLIP-seq
MIRT766336	hsa-miR-202	CLIP-seq
MIRT766337	hsa-miR-3160-3p	CLIP-seq
MIRT766338	hsa-miR-3161	CLIP-seq
MIRT766339	hsa-miR-3174	CLIP-seq
MIRT766340	hsa-miR-342-3p	CLIP-seq
MIRT766341	hsa-miR-3606	CLIP-seq
MIRT766342	hsa-miR-4261	CLIP-seq
MIRT766343	hsa-miR-4458	CLIP-seq
MIRT766344	hsa-miR-4496	CLIP-seq
MIRT766345	hsa-miR-4500	CLIP-seq
MIRT766346	hsa-miR-4637	CLIP-seq
MIRT766347	hsa-miR-4729	CLIP-seq
MIRT766348	hsa-miR-4795-3p	CLIP-seq
MIRT766349	hsa-miR-548a-5p	CLIP-seq
MIRT766350	hsa-miR-548ab	CLIP-seq
MIRT766351	hsa-miR-548ak	CLIP-seq
MIRT766352	hsa-miR-548b-5p	CLIP-seq
MIRT766353	hsa-miR-548c-5p	CLIP-seq
MIRT766354	hsa-miR-548d-5p	CLIP-seq
MIRT766355	hsa-miR-548h	CLIP-seq
MIRT766356	hsa-miR-548i	CLIP-seq
MIRT766357	hsa-miR-548j	CLIP-seq
MIRT766358	hsa-miR-548k	CLIP-seq
MIRT766359	hsa-miR-548l	CLIP-seq
MIRT766360	hsa-miR-548w	CLIP-seq
MIRT766361	hsa-miR-548y	CLIP-seq
MIRT766362	hsa-miR-556-3p	CLIP-seq
MIRT766363	hsa-miR-559	CLIP-seq
MIRT766364	hsa-miR-921	CLIP-seq
MIRT766365	hsa-miR-98	CLIP-seq
MIRT2167122	hsa-miR-4666-5p	CLIP-seq
MIRT766349	hsa-miR-548a-5p	CLIP-seq
MIRT766350	hsa-miR-548ab	CLIP-seq
MIRT766351	hsa-miR-548ak	CLIP-seq
MIRT766352	hsa-miR-548b-5p	CLIP-seq
MIRT766353	hsa-miR-548c-5p	CLIP-seq
MIRT766354	hsa-miR-548d-5p	CLIP-seq
MIRT766355	hsa-miR-548h	CLIP-seq
MIRT766356	hsa-miR-548i	CLIP-seq
MIRT766357	hsa-miR-548j	CLIP-seq
MIRT766358	hsa-miR-548k	CLIP-seq
MIRT766359	hsa-miR-548l	CLIP-seq
MIRT766360	hsa-miR-548w	CLIP-seq
MIRT766361	hsa-miR-548y	CLIP-seq
MIRT766363	hsa-miR-559	CLIP-seq
MIRT2425950	hsa-miR-1273f	CLIP-seq
MIRT2425951	hsa-miR-143	CLIP-seq
MIRT2425952	hsa-miR-147	CLIP-seq
MIRT2425953	hsa-miR-194	CLIP-seq
MIRT2425954	hsa-miR-2054	CLIP-seq
MIRT2425955	hsa-miR-219-5p	CLIP-seq
MIRT2425956	hsa-miR-302f	CLIP-seq
MIRT2425957	hsa-miR-3074-3p	CLIP-seq
MIRT2425958	hsa-miR-3146	CLIP-seq
MIRT2425959	hsa-miR-34c-3p	CLIP-seq
MIRT2425960	hsa-miR-365	CLIP-seq
MIRT2425961	hsa-miR-3682-5p	CLIP-seq
MIRT2425962	hsa-miR-3941	CLIP-seq
MIRT2425963	hsa-miR-4263	CLIP-seq
MIRT2425964	hsa-miR-433	CLIP-seq
MIRT2425965	hsa-miR-4445	CLIP-seq
MIRT2425966	hsa-miR-4499	CLIP-seq
MIRT2425967	hsa-miR-4508	CLIP-seq
MIRT2425968	hsa-miR-4532	CLIP-seq
MIRT2425969	hsa-miR-466	CLIP-seq
MIRT2425970	hsa-miR-4672	CLIP-seq
MIRT2425971	hsa-miR-4708-5p	CLIP-seq
MIRT2425972	hsa-miR-4719	CLIP-seq
MIRT2425973	hsa-miR-4731-3p	CLIP-seq
MIRT2425974	hsa-miR-4770	CLIP-seq
MIRT2425975	hsa-miR-4782-3p	CLIP-seq
MIRT766348	hsa-miR-4795-3p	CLIP-seq
MIRT2425976	hsa-miR-4799-5p	CLIP-seq
MIRT2425977	hsa-miR-4801	CLIP-seq
MIRT2425978	hsa-miR-508-3p	CLIP-seq
MIRT2425979	hsa-miR-548u	CLIP-seq
MIRT2425980	hsa-miR-576-5p	CLIP-seq
MIRT2425981	hsa-miR-767-3p	CLIP-seq
MIRT2469737	hsa-miR-1226	CLIP-seq
MIRT2469738	hsa-miR-1248	CLIP-seq
MIRT2469739	hsa-miR-1270	CLIP-seq
MIRT2425950	hsa-miR-1273f	CLIP-seq
MIRT2469740	hsa-miR-1287	CLIP-seq
MIRT2469741	hsa-miR-129-3p	CLIP-seq
MIRT766335	hsa-miR-1294	CLIP-seq
MIRT2469742	hsa-miR-138	CLIP-seq
MIRT2425951	hsa-miR-143	CLIP-seq
MIRT2469743	hsa-miR-1470	CLIP-seq
MIRT2469744	hsa-miR-15a	CLIP-seq
MIRT2469745	hsa-miR-15b	CLIP-seq
MIRT2469746	hsa-miR-16	CLIP-seq
MIRT2469747	hsa-miR-181a	CLIP-seq
MIRT2469748	hsa-miR-181b	CLIP-seq
MIRT2469749	hsa-miR-181c	CLIP-seq
MIRT2469750	hsa-miR-181d	CLIP-seq
MIRT2469751	hsa-miR-193a-3p	CLIP-seq
MIRT2469752	hsa-miR-193b	CLIP-seq
MIRT2425953	hsa-miR-194	CLIP-seq
MIRT2469753	hsa-miR-195	CLIP-seq
MIRT2469754	hsa-miR-197	CLIP-seq
MIRT2425954	hsa-miR-2054	CLIP-seq
MIRT2469755	hsa-miR-214	CLIP-seq
MIRT2425956	hsa-miR-302f	CLIP-seq
MIRT2469756	hsa-miR-31	CLIP-seq
MIRT2469757	hsa-miR-3125	CLIP-seq
MIRT2469758	hsa-miR-3128	CLIP-seq
MIRT2469759	hsa-miR-3130-3p	CLIP-seq
MIRT2469760	hsa-miR-3135b	CLIP-seq
MIRT2469761	hsa-miR-3152-5p	CLIP-seq
MIRT2469762	hsa-miR-3157-3p	CLIP-seq
MIRT2469763	hsa-miR-3160-5p	CLIP-seq
MIRT766338	hsa-miR-3161	CLIP-seq
MIRT766339	hsa-miR-3174	CLIP-seq
MIRT2469764	hsa-miR-330-3p	CLIP-seq
MIRT766341	hsa-miR-3606	CLIP-seq
MIRT2469765	hsa-miR-3613-3p	CLIP-seq
MIRT2469766	hsa-miR-3614-3p	CLIP-seq
MIRT2469767	hsa-miR-3619-3p	CLIP-seq
MIRT2469768	hsa-miR-3619-5p	CLIP-seq
MIRT2469769	hsa-miR-3667-3p	CLIP-seq
MIRT2469770	hsa-miR-3916	CLIP-seq
MIRT2425962	hsa-miR-3941	CLIP-seq
MIRT2469771	hsa-miR-409-5p	CLIP-seq
MIRT2469772	hsa-miR-424	CLIP-seq
MIRT2469773	hsa-miR-4262	CLIP-seq
MIRT2425963	hsa-miR-4263	CLIP-seq
MIRT2469774	hsa-miR-4290	CLIP-seq
MIRT2469775	hsa-miR-4291	CLIP-seq
MIRT2469776	hsa-miR-4312	CLIP-seq
MIRT2469777	hsa-miR-4446-5p	CLIP-seq
MIRT2425966	hsa-miR-4499	CLIP-seq
MIRT2469778	hsa-miR-4524	CLIP-seq
MIRT2469779	hsa-miR-4535	CLIP-seq
MIRT2425969	hsa-miR-466	CLIP-seq
MIRT2469780	hsa-miR-4663	CLIP-seq
MIRT2469781	hsa-miR-4667-3p	CLIP-seq
MIRT2469782	hsa-miR-4670-3p	CLIP-seq
MIRT2425970	hsa-miR-4672	CLIP-seq
MIRT2469783	hsa-miR-4683	CLIP-seq
MIRT2425971	hsa-miR-4708-5p	CLIP-seq
MIRT2469784	hsa-miR-4713-5p	CLIP-seq
MIRT2425972	hsa-miR-4719	CLIP-seq
MIRT2425973	hsa-miR-4731-3p	CLIP-seq
MIRT2469785	hsa-miR-4733-3p	CLIP-seq
MIRT2469786	hsa-miR-4755-5p	CLIP-seq
MIRT2469787	hsa-miR-4768-5p	CLIP-seq
MIRT2425974	hsa-miR-4770	CLIP-seq
MIRT2469788	hsa-miR-4774-3p	CLIP-seq
MIRT2469789	hsa-miR-4776-5p	CLIP-seq
MIRT2469790	hsa-miR-4786-3p	CLIP-seq
MIRT2425976	hsa-miR-4799-5p	CLIP-seq
MIRT2425977	hsa-miR-4801	CLIP-seq
MIRT2469791	hsa-miR-492	CLIP-seq
MIRT2469792	hsa-miR-495	CLIP-seq
MIRT2469793	hsa-miR-497	CLIP-seq
MIRT2469794	hsa-miR-503	CLIP-seq
MIRT2469795	hsa-miR-512-3p	CLIP-seq
MIRT2425979	hsa-miR-548u	CLIP-seq
MIRT2469796	hsa-miR-576-3p	CLIP-seq
MIRT2425980	hsa-miR-576-5p	CLIP-seq
MIRT2469797	hsa-miR-583	CLIP-seq
MIRT2469798	hsa-miR-620	CLIP-seq
MIRT2469799	hsa-miR-628-5p	CLIP-seq
MIRT2469800	hsa-miR-646	CLIP-seq
MIRT2469801	hsa-miR-653	CLIP-seq
MIRT2469802	hsa-miR-670	CLIP-seq
MIRT2469803	hsa-miR-671-5p	CLIP-seq
MIRT2469804	hsa-miR-761	CLIP-seq
MIRT2469805	hsa-miR-766	CLIP-seq
MIRT2469806	hsa-miR-767-5p	CLIP-seq
MIRT2469807	hsa-miR-874	CLIP-seq
MIRT2469808	hsa-miR-892b	CLIP-seq
MIRT766364	hsa-miR-921	CLIP-seq
MIRT2469809	hsa-miR-922	CLIP-seq
MIRT766326	hsa-let-7a	CLIP-seq
MIRT766327	hsa-let-7b	CLIP-seq
MIRT766328	hsa-let-7c	CLIP-seq
MIRT766329	hsa-let-7d	CLIP-seq
MIRT766330	hsa-let-7e	CLIP-seq
MIRT766331	hsa-let-7f	CLIP-seq
MIRT766332	hsa-let-7g	CLIP-seq
MIRT766333	hsa-let-7i	CLIP-seq
MIRT2469737	hsa-miR-1226	CLIP-seq
MIRT2674414	hsa-miR-1245	CLIP-seq
MIRT2469738	hsa-miR-1248	CLIP-seq
MIRT2469739	hsa-miR-1270	CLIP-seq
MIRT2425950	hsa-miR-1273f	CLIP-seq
MIRT2469740	hsa-miR-1287	CLIP-seq
MIRT2469741	hsa-miR-129-3p	CLIP-seq
MIRT766335	hsa-miR-1294	CLIP-seq
MIRT2469742	hsa-miR-138	CLIP-seq
MIRT2425951	hsa-miR-143	CLIP-seq
MIRT2469743	hsa-miR-1470	CLIP-seq
MIRT2469744	hsa-miR-15a	CLIP-seq
MIRT2469745	hsa-miR-15b	CLIP-seq
MIRT2469746	hsa-miR-16	CLIP-seq
MIRT2469747	hsa-miR-181a	CLIP-seq
MIRT2469748	hsa-miR-181b	CLIP-seq
MIRT2469749	hsa-miR-181c	CLIP-seq
MIRT2469750	hsa-miR-181d	CLIP-seq
MIRT2469751	hsa-miR-193a-3p	CLIP-seq
MIRT2469752	hsa-miR-193b	CLIP-seq
MIRT2425953	hsa-miR-194	CLIP-seq
MIRT2469753	hsa-miR-195	CLIP-seq
MIRT2469754	hsa-miR-197	CLIP-seq
MIRT766336	hsa-miR-202	CLIP-seq
MIRT2425954	hsa-miR-2054	CLIP-seq
MIRT2469755	hsa-miR-214	CLIP-seq
MIRT2674415	hsa-miR-216a	CLIP-seq
MIRT2425956	hsa-miR-302f	CLIP-seq
MIRT2469756	hsa-miR-31	CLIP-seq
MIRT2469757	hsa-miR-3125	CLIP-seq
MIRT2469758	hsa-miR-3128	CLIP-seq
MIRT2469759	hsa-miR-3130-3p	CLIP-seq
MIRT2469760	hsa-miR-3135b	CLIP-seq
MIRT2469761	hsa-miR-3152-5p	CLIP-seq
MIRT2469762	hsa-miR-3157-3p	CLIP-seq
MIRT2469763	hsa-miR-3160-5p	CLIP-seq
MIRT766338	hsa-miR-3161	CLIP-seq
MIRT766339	hsa-miR-3174	CLIP-seq
MIRT2674416	hsa-miR-34a	CLIP-seq
MIRT2674417	hsa-miR-34c-5p	CLIP-seq
MIRT766341	hsa-miR-3606	CLIP-seq
MIRT2469765	hsa-miR-3613-3p	CLIP-seq
MIRT2469766	hsa-miR-3614-3p	CLIP-seq
MIRT2469767	hsa-miR-3619-3p	CLIP-seq
MIRT2469768	hsa-miR-3619-5p	CLIP-seq
MIRT2674418	hsa-miR-3664-5p	CLIP-seq
MIRT2469769	hsa-miR-3667-3p	CLIP-seq
MIRT2674419	hsa-miR-3682-3p	CLIP-seq
MIRT2469770	hsa-miR-3916	CLIP-seq
MIRT2674420	hsa-miR-3921	CLIP-seq
MIRT2425962	hsa-miR-3941	CLIP-seq
MIRT2469771	hsa-miR-409-5p	CLIP-seq
MIRT2469772	hsa-miR-424	CLIP-seq
MIRT766342	hsa-miR-4261	CLIP-seq
MIRT2469773	hsa-miR-4262	CLIP-seq
MIRT2425963	hsa-miR-4263	CLIP-seq
MIRT2674421	hsa-miR-4272	CLIP-seq
MIRT2674422	hsa-miR-4279	CLIP-seq
MIRT2674423	hsa-miR-4286	CLIP-seq
MIRT2469774	hsa-miR-4290	CLIP-seq
MIRT2469775	hsa-miR-4291	CLIP-seq
MIRT2469776	hsa-miR-4312	CLIP-seq
MIRT2469777	hsa-miR-4446-5p	CLIP-seq
MIRT766343	hsa-miR-4458	CLIP-seq
MIRT766344	hsa-miR-4496	CLIP-seq
MIRT2425966	hsa-miR-4499	CLIP-seq
MIRT2674424	hsa-miR-449a	CLIP-seq
MIRT2674425	hsa-miR-449b	CLIP-seq
MIRT766345	hsa-miR-4500	CLIP-seq
MIRT2674426	hsa-miR-4502	CLIP-seq
MIRT2469778	hsa-miR-4524	CLIP-seq
MIRT2469779	hsa-miR-4535	CLIP-seq
MIRT2674427	hsa-miR-4650-3p	CLIP-seq
MIRT2674428	hsa-miR-4653-5p	CLIP-seq
MIRT2425969	hsa-miR-466	CLIP-seq
MIRT2469780	hsa-miR-4663	CLIP-seq
MIRT2469781	hsa-miR-4667-3p	CLIP-seq
MIRT2674429	hsa-miR-4668-3p	CLIP-seq
MIRT2469782	hsa-miR-4670-3p	CLIP-seq
MIRT2425970	hsa-miR-4672	CLIP-seq
MIRT2469783	hsa-miR-4683	CLIP-seq
MIRT2674430	hsa-miR-4695-3p	CLIP-seq
MIRT2425971	hsa-miR-4708-5p	CLIP-seq
MIRT2469784	hsa-miR-4713-5p	CLIP-seq
MIRT2674431	hsa-miR-4714-5p	CLIP-seq
MIRT2425972	hsa-miR-4719	CLIP-seq
MIRT2425973	hsa-miR-4731-3p	CLIP-seq
MIRT2469785	hsa-miR-4733-3p	CLIP-seq
MIRT2469786	hsa-miR-4755-5p	CLIP-seq
MIRT2674432	hsa-miR-4766-5p	CLIP-seq
MIRT2469787	hsa-miR-4768-5p	CLIP-seq
MIRT2425974	hsa-miR-4770	CLIP-seq
MIRT2469788	hsa-miR-4774-3p	CLIP-seq
MIRT2469789	hsa-miR-4776-5p	CLIP-seq
MIRT2469790	hsa-miR-4786-3p	CLIP-seq
MIRT2425976	hsa-miR-4799-5p	CLIP-seq
MIRT2425977	hsa-miR-4801	CLIP-seq
MIRT2469791	hsa-miR-492	CLIP-seq
MIRT2469792	hsa-miR-495	CLIP-seq
MIRT2469793	hsa-miR-497	CLIP-seq
MIRT2469794	hsa-miR-503	CLIP-seq
MIRT2469795	hsa-miR-512-3p	CLIP-seq
MIRT2674433	hsa-miR-543	CLIP-seq
MIRT766349	hsa-miR-548a-5p	CLIP-seq
MIRT766350	hsa-miR-548ab	CLIP-seq
MIRT766351	hsa-miR-548ak	CLIP-seq
MIRT766352	hsa-miR-548b-5p	CLIP-seq
MIRT766353	hsa-miR-548c-5p	CLIP-seq
MIRT766354	hsa-miR-548d-5p	CLIP-seq
MIRT766355	hsa-miR-548h	CLIP-seq
MIRT766356	hsa-miR-548i	CLIP-seq
MIRT766357	hsa-miR-548j	CLIP-seq
MIRT766358	hsa-miR-548k	CLIP-seq
MIRT766359	hsa-miR-548l	CLIP-seq
MIRT2425979	hsa-miR-548u	CLIP-seq
MIRT766360	hsa-miR-548w	CLIP-seq
MIRT766361	hsa-miR-548y	CLIP-seq
MIRT766363	hsa-miR-559	CLIP-seq
MIRT2674434	hsa-miR-568	CLIP-seq
MIRT2469796	hsa-miR-576-3p	CLIP-seq
MIRT2425980	hsa-miR-576-5p	CLIP-seq
MIRT2469797	hsa-miR-583	CLIP-seq
MIRT2469798	hsa-miR-620	CLIP-seq
MIRT2469799	hsa-miR-628-5p	CLIP-seq
MIRT2674435	hsa-miR-633	CLIP-seq
MIRT2469800	hsa-miR-646	CLIP-seq
MIRT2469801	hsa-miR-653	CLIP-seq
MIRT2469802	hsa-miR-670	CLIP-seq
MIRT2469803	hsa-miR-671-5p	CLIP-seq
MIRT2469804	hsa-miR-761	CLIP-seq
MIRT2469805	hsa-miR-766	CLIP-seq
MIRT2469806	hsa-miR-767-5p	CLIP-seq
MIRT2469807	hsa-miR-874	CLIP-seq
MIRT2469808	hsa-miR-892b	CLIP-seq
MIRT766364	hsa-miR-921	CLIP-seq
MIRT2469809	hsa-miR-922	CLIP-seq
MIRT766365	hsa-miR-98	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
ERG	Activation	19396168
EZH2	Repression	22514714

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001542	Process	Ovulation from ovarian follicle	IEA
GO:0001822	Process	Kidney development	IEA
GO:0004222	Function	Metalloendopeptidase activity	IBA	21873635
GO:0004222	Function	Metalloendopeptidase activity	IDA	11278559
GO:0005515	Function	Protein binding	IPI	32296183, 32814053
GO:0005604	Component	Basement membrane	IEA
GO:0006508	Process	Proteolysis	IEA
GO:0007229	Process	Integrin-mediated signaling pathway	TAS	8995297
GO:0008201	Function	Heparin binding	IEA
GO:0008237	Function	Metallopeptidase activity	TAS	10438512
GO:0008270	Function	Zinc ion binding	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	TAS	10438512
GO:0016525	Process	Negative regulation of angiogenesis	IDA	10438512
GO:0030198	Process	Extracellular matrix organization	IBA	21873635
GO:0031012	Component	Extracellular matrix	IBA	21873635
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0060347	Process	Heart trabecula formation	IEA
GO:0062023	Component	Collagen-containing extracellular matrix	HDA	28327460
GO:1900087	Process	Positive regulation of G1/S transition of mitotic cell cycle	IGI	28890348
GO:1904707	Process	Positive regulation of vascular associated smooth muscle cell proliferation	IGI	28890348
GO:1904754	Process	Positive regulation of vascular associated smooth muscle cell migration	IGI	28890348

Other IDs

• MIM: 605174
• HGNC: 217
• e!Ensembl: ENSG00000154734

Protein

• UniProt ID: Q9UHI8
• Protein name: A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAM-TS 1) (ADAM-TS1) (ADAMTS-1) (EC 3.4.24.-) (METH-1)
• Protein function: Metalloprotease which cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (By similarity). Also cleaves COMP (PubMed:39672391). Has
• PDB: 2JIH, 2V4B, 3Q2G, 3Q2H
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01562	Pep_M12B_propep	48 → 174	Reprolysin family propeptide	Family
  PF01421	Reprolysin	258 → 467	Reprolysin (M12B) family zinc metalloprotease	Domain
  PF17771	ADAM_CR_2	478 → 546	ADAM cysteine-rich domain	Domain
  PF00090	TSP_1	563 → 613	Thrombospondin type 1 domain	Domain
  PF05986	ADAM_spacer1	725 → 843	ADAM-TS Spacer 1	Family
  PF19030	TSP1_ADAMTS	858 → 909		Domain
  PF19030	TSP1_ADAMTS	912 → 966		Domain

• Sequence:

  MQRAVPEGFGRRKLGSDMGNAERAPGSRSFGPVPTLLLLAAALLAVSDALGRPSEEDEEL
  VVPELERAPGHGTTRLRLHAFDQQLDLELRPDSSFLAPGFTLQNVGRKSGSETPLPETDL
  AHCFYSGTVNGDPSSAAALSLCEGVRGAFYLLGEAYFIQPLPAASERLATAAPGEKPPAP
  LQFHLLRRNRQGDVGGTCGVVDDEPRPTGKAETEDEDEGTEGEDEGAQWSPQDPALQGVG
  QPTGTGSIRKKRFVSSHRYVETMLVADQSMAEFHGSGLKHYLLTLFSVAARLYKHPSIRN
  SVSLVVVKILVIHDEQKGPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQD
  LCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQAAFTTAHELGHVFNMPHDDAKQCASL
  NGVNQDSHMMASMLSNLDHSQPWSPCSAYMITSFLDNGHGECLMDKPQNPIQLPGDLPGT
  SYDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQTKHFPWADGTSCGEGKWC
  INGKCVNKTDRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEG
  KRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKL
  ICQAKGIGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGGN
  GSTCKKISGSVTSAKPGYHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADGTYILN
  GDYTLSTLEQDIMYKGVVLRYSGSSAALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTY
  FVKKKKESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKPAS
  TRPCADHPCPQWQLGEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESCDPLKKPKHFIDF
  CTMAECS

• Sequence length: 967

Pathways

Reactome:

Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Alzheimer disease	Familial Alzheimer Disease (FAD), Alzheimer Disease, Late Onset, Alzheimer Disease, Early Onset, Alzheimer`s Disease, Alzheimer`s Disease, Focal Onset	rs63750215, rs28936379, rs63749851, rs63749884, rs28936380, rs63750048, rs63750579, rs63750264, rs63749964, rs63750671, rs281865161, rs63750066, rs63750399, rs63750734, rs63751039, rs63750973, rs63749810, rs63750643, rs193922916, rs63750306, rs63750590, rs63750526, rs63751235, rs661, rs63751037, rs63749885, rs63750231, rs63751229, rs63751272, rs63751223, rs63750391, rs63751163, rs281875357, rs63751141, rs63750082, rs121917807, rs63751399, rs63750265, rs63751144, rs63750886, rs63751068, rs121917808, rs63749891, rs63750083, rs63749824, rs63750577, rs267606983, rs63750218, rs63751287, rs63750900, rs145518263, rs63751475, rs63750450, rs63749805, rs63751278, rs63751106, rs63750004, rs63749806, rs63751024, rs63750248, rs63750779, rs63751139, rs63750219, rs63750298, rs63750687, rs63750851, rs1553268799, rs1561901881, rs1561905293, rs866101707, rs1566638673, rs63750009, rs1566656702, rs1566657804, rs1567885728, rs1568339995, rs1566630791, rs1555358260, rs63750964, rs1594998354, rs63751316	30820047
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243	23289900
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs10520699, rs11852999, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038	23289900
Lung carcinoma	Non-Small Cell Lung Carcinoma	rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355, rs121912470, rs121913273, rs121913281, rs121913348, rs727503093, rs121913353, rs397516890, rs397516896, rs121913378, rs397516897, rs397516977, rs397516978, rs397516979, rs397516980, rs397516981, rs397516982, rs121913240, rs17851045, rs397517086, rs121913428, rs397517094, rs397517098, rs397517106, rs121913465, rs397517108, rs397517111, rs397517112, rs397517114, rs397517116, rs1554350366, rs397517127, rs397517200, rs397517202, rs121913283, rs121913370, rs121913357, rs727503106, rs121913238, rs727503108, rs397517040, rs397516976, rs1555618025, rs1057519729, rs1584238193	19027488
Marfan syndrome	Mammary Carcinoma, Human	rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465, rs137854466, rs137854467, rs387906547, rs387906548, rs137854469, rs137854473, rs1131692050, rs112989722, rs137854474, rs137854476, rs140593, rs1555395819, rs137854478, rs137854479, rs137854480, rs137854481, rs137854482, rs137854483, rs137854484, rs137854485, rs112289537, rs193922181, rs193922182, rs193922185, rs140603, rs193922187, rs193922188, rs193921256, rs112660651, rs193922193, rs193922194, rs193922197, rs193922198, rs193922199, rs193922203, rs193922204, rs193922205, rs193922206, rs111401431, rs193922207, rs113871094, rs111671429, rs193922216, rs193922219, rs193922220, rs193922223, rs193922224, rs193922225, rs193922226, rs193922227, rs193922228, rs193922230, rs193922235, rs147195031, rs193922236, rs193922239, rs193922240, rs193922241, rs193922246, rs397514558, rs398122934, rs397515753, rs397515754, rs397515755, rs397515756, rs397515757, rs113812345, rs397515758, rs397515759, rs397515762, rs25403, rs397515765, rs397515766, rs397515767, rs397515768, rs397515769, rs397515770, rs397515771, rs25404, rs397515773, rs397515774, rs397515775, rs397515776, rs397515778, rs397515779, rs397515781, rs112202622, rs397515782, rs397515784, rs397515785, rs397515786, rs397515788, rs397515789, rs397515790, rs397515791, rs397515792, rs397515793, rs397515794, rs397515797, rs397515798, rs397515799, rs397515801, rs397515802, rs397515803, rs397515804, rs397515805, rs397515808, rs397515810, rs397515811, rs397515812, rs111231312, rs267606798, rs397515814, rs113905529, rs397515816, rs397515817, rs397515818, rs397515819, rs397515820, rs363853, rs113249837, rs397515821, rs111929350, rs397515823, rs397515824, rs113086760, rs397515825, rs397515826, rs397515827, rs363807, rs397515828, rs397515829, rs397515830, rs397515831, rs397515833, rs111687884, rs113080385, rs397515834, rs397515836, rs113001196, rs397515840, rs397515845, rs397515846, rs397515847, rs397515848, rs397515851, rs397515852, rs397515853, rs397515854, rs111856492, rs397515859, rs397515861, rs397515863, rs397515864, rs397515865, rs397515866, rs397515867, rs137854855, rs199474693, rs587782944, rs587782947, rs587782948, rs672601352, rs876658120, rs727504651, rs727503054, rs727504315, rs727504411, rs727503057, rs727504454, rs200309328, rs363811, rs727504410, rs363821, rs727504347, rs727505006, rs727505110, rs730880356, rs727505269, rs727503058, rs727504421, rs730880107, rs730880104, rs730880103, rs730880102, rs730880101, rs730880106, rs730880100, rs730880105, rs730880099, rs112645512, rs730880108, rs730880098, rs730880097, rs794728321, rs794728283, rs794728280, rs794728336, rs794728272, rs794728160, rs794728271, rs794728270, rs794728319, rs794728262, rs794728251, rs76702162, rs794728335, rs794728334, rs794728246, rs763091520, rs794728333, rs794728237, rs761857514, rs794728234, rs140630, rs794728231, rs794728228, rs794728225, rs794728308, rs794728216, rs794728221, rs763449629, rs201058219, rs794728210, rs794728208, rs794728206, rs794728199, rs794728195, rs794728194, rs794728193, rs794728190, rs1555399381, rs794728176, rs1555399968, rs113422242, rs794728326, rs794728166, rs794728325, rs794728165, rs794728162, rs794728213, rs869025417, rs112642323, rs869025416, rs869025415, rs869025424, rs869025423, rs869025414, rs869025422, rs869025413, rs869025412, rs869025411, rs869025418, rs869025426, rs869025406, rs869025421, rs869025425, rs869025404, rs869025420, rs869025403, rs398122833, rs876657645, rs878853686, rs878853676, rs886038919, rs886038795, rs187553035, rs886038869, rs886038949, rs886038967, rs886038976, rs886038848, rs886038940, rs886038877, rs886039038, rs886038817, rs886038963, rs886039036, rs886038797, rs886039550, rs886041482, rs1057517855, rs1057518912, rs1057518973, rs1057519502, rs1057521100, rs1057521102, rs1057518881, rs1057520617, rs1057521101, rs1555394445, rs369058466, rs1060501069, rs1060501031, rs778966916, rs1060501043, rs1555397663, rs1060501017, rs1060501094, rs1060501065, rs1555393848, rs1555394151, rs1060501051, rs1060501013, rs1060501054, rs1060501048, rs1060501089, rs1060501039, rs1555398160, rs1060501022, rs1060501024, rs1060501086, rs1060501058, rs1060501036, rs1060501100, rs1060501042, rs1060501059, rs1555397743, rs1060501021, rs1060501027, rs1060501096, rs1060501038, rs1060501050, rs1064794130, rs112118237, rs1064793980, rs1064793118, rs1064793636, rs1064794282, rs1064793559, rs1085307921, rs1085308004, rs1085307468, rs112907302, rs1131691479, rs1131691373, rs1131691467, rs1131691938, rs1131691311, rs1131691806, rs1131691317, rs1555393827, rs363804, rs1555397738, rs1555399144, rs1555400274, rs1555394195, rs1555398836, rs113543334, rs1555399825, rs1555394626, rs1555395256, rs1555395257, rs1555396427, rs1555397548, rs1555398173, rs1555404803, rs1232880706, rs1555393825, rs1555394567, rs1555396998, rs1555394928, rs1555397203, rs112375043, rs1555397720, rs140599, rs1555399150, rs1555400373, rs1555405041, rs1555395229, rs1555397671, rs775417975, rs1555398774, rs1555399368, rs1555394904, rs1555395987, rs1555397424, rs1555398377, rs1555398835, rs1555401011, rs1555405043, rs1555394580, rs1555397404, rs1555398511, rs1555395826, rs1555399372, rs1555399821, rs1555399836, rs1555400063, rs363810, rs1555397655, rs1555395756, rs1555395742, rs1555393844, rs112550005, rs1555395002, rs1555395658, rs765387131, rs1555396429, rs1555396835, rs1555397014, rs1555397016, rs778710767, rs1555397557, rs1555397704, rs140648, rs1555398406, rs1555398681, rs1555399257, rs1555399361, rs1555399764, rs1555405056, rs1555393510, rs1555395980, rs1555396789, rs1555399094, rs1555399378, rs1555399816, rs1555395645, rs371097218, rs1555398278, rs1555394238, rs1555396418, rs1206813753, rs1555399271, rs1555405044, rs113544411, rs1555395663, rs1555397216, rs1555398989, rs1555399149, rs1555401670, rs1555395001, rs1445085747, rs1555393538, rs1555393565, rs1404133653, rs1555394450, rs1555394581, rs1555394633, rs1555394900, rs1555395189, rs1555395261, rs1052480459, rs1555395480, rs1555395670, rs363806, rs1555395820, rs1555396419, rs1555396765, rs1296209846, rs794728233, rs1555396853, rs1555396863, rs1555397197, rs1555397204, rs1555397212, rs1555397713, rs1555397736, rs1555398139, rs1555398144, rs1555398409, rs1555398510, rs1555398520, rs1555398524, rs1555398667, rs1555399089, rs1555399482, rs1555399763, rs1555401002, rs794728323, rs1555393508, rs1555393514, rs1555393525, rs1555393532, rs1555393653, rs1555393657, rs1555393824, rs1555393831, rs112196241, rs1555393847, rs1555393862, rs1555393863, rs1555393866, rs113935744, rs1555393882, rs1555393886, rs1555393889, rs1555394138, rs1555394144, rs1555394146, rs1555394148, rs1555394149, rs1555394152, rs1555394153, rs1555394189, rs1555394197, rs1555394206, rs1555394212, rs1555394218, rs1555394220, rs1555394235, rs1555394245, rs1555394246, rs1057520728, rs1555394390, rs1555394391, rs537570299, rs1555394397, rs1555394398, rs1555394399, rs1555394402, rs1555394407, rs1555394412, rs1555394435, rs1555394436, rs1555394441, rs1555394556, rs1555394557, rs1555394559, rs1555394561, rs1555394570, rs397515844, rs1555394571, rs1555394574, rs1555394579, rs1555394582, rs534811966, rs111588631, rs1555394628, rs1555394629, rs1555394630, rs1555394631, rs1555394641, rs1555394644, rs1555394647, rs1555394756, rs886051245, rs1555394775, rs1555394776, rs1555394777, rs1555394779, rs1555394780, rs1555394783, rs1555394901, rs1555394906, rs1555394925, rs794728253, rs886039158, rs1555395013, rs1555395187, rs1555395188, rs1555395203, rs1555395205, rs363815, rs1246984265, rs794728245, rs1555395263, rs1555395267, rs1555395456, rs1555395475, rs1555395482, rs1555395638, rs1555395641, rs1555395648, rs1555395653, rs1555395659, rs111239111, rs1555395745, rs1555395747, rs1555395753, rs1555395757, rs1555395766, rs1555395767, rs1555395843, rs1555395846, rs1555395849, rs1555395978, rs1555395981, rs1555395984, rs1555395989, rs1555395990, rs1260109901, rs1555396186, rs1555396188, rs1555396198, rs1555396199, rs1555396201, rs1555396202, rs1555396205, rs1555396213, rs1555396424, rs1555396426, rs1555396428, rs1555396435, rs1555396630, rs1555396635, rs1555396636, rs1555396639, rs1555396757, rs1555396769, rs1555396838, rs1555396844, rs140627, rs1555396858, rs1555396990, rs1555396991, rs1555396993, rs769588424, rs1555397022, rs1555397024, rs1555397160, rs1555397174, rs1555397176, rs1555397193, rs1555397209, rs1555397210, rs1555397214, rs1060501076, rs113082854, rs113693945, rs111978932, rs1555397403, rs1555397419, rs1555397420, rs1555397421, rs1555397536, rs1555397537, rs1555397540, rs1555397542, rs1555397543, rs1555397545, rs1555397546, rs1555397670, rs1555397692, rs1555397718, rs1555397723, rs1555397744, rs113393517, rs1555398148, rs1555398152, rs1555398174, rs1555398176, rs1555398179, rs1555398282, rs1555398287, rs1555398380, rs1555398394, rs1555398397, rs1555398401, rs1555398404, rs1555398407, rs1555398413, rs1555398501, rs1555398508, rs1555398512, rs1555398513, rs1555398515, rs1555398521, rs794728205, rs1555398527, rs1555398551, rs1060501075, rs1555398566, rs1555398572, rs1555398580, rs1555398582, rs140597, rs1555398622, rs1555398624, rs1555398625, rs112547596, rs1555398627, rs1555398633, rs1555398637, rs1555398642, rs778867355, rs1555398648, rs1555398659, rs1293095681, rs1060501040, rs987202268, rs1555398672, rs1555398673, rs1555398677, rs1555398793, rs1555398803, rs1555398811, rs1555398826, rs1555398833, rs1555398974, rs1555398981, rs778900586, rs1555398988, rs1555398994, rs1555398995, rs1555398996, rs1555399093, rs869025405, rs1555399101, rs1555399146, rs1555399160, rs1555399162, rs1555399164, rs1555399165, rs1555399193, rs1555399195, rs1555399202, rs1555399204, rs1555399206, rs201778577, rs1555399210, rs1555399214, rs1555399270, rs1555399273, rs1555399281, rs1555399371, rs1555399385, rs1555399477, rs1555399484, rs1555399761, rs1555399775, rs1555399802, rs1555399804, rs1555399837, rs1555399840, rs1555399940, rs1555399944, rs1555399949, rs1555399953, rs1555399954, rs1555399955, rs1555399959, rs1555399962, rs1555399963, rs1060501041, rs1555399974, rs1555399976, rs1555399977, rs1555400049, rs794728172, rs1555400062, rs1555400064, rs1555400066, rs1555400267, rs1555400268, rs1555400278, rs794728168, rs1555400279, rs1156747241, rs1555400288, rs1555400371, rs1555400372, rs1555400379, rs1555400385, rs587782943, rs1555400387, rs1555400406, rs1439533354, rs746201757, rs1555400595, rs1555400603, rs1555400604, rs1555400606, rs1555400609, rs752010116, rs1555400612, rs1555400616, rs1555401004, rs1555401005, rs146348130, rs1555401667, rs1555401671, rs1555401676, rs1555401679, rs1555401687, rs1555401689, rs1555401695, rs1555401697, rs1555401701, rs1555404799, rs1555404800, rs200295020, rs1555404810, rs1555404820, rs1555405031, rs1555405039, rs1555405045, rs1555405530, rs794728292, rs1555405533, rs1555405536, rs1555405537, rs111764111, rs1555405658, rs1555405664, rs774371494, rs1555405673, rs1555407399, rs1555407414, rs1555407423, rs1555407429, rs886041536, rs1555404806, rs1566911709, rs1566913974, rs1566894226, rs1566895223, rs1566897376, rs1566902526, rs1566915277, rs1566897374, rs1566897420, rs1566891655, rs1346043320, rs1566922396, rs1566891706, rs1566894783, rs1566913670, rs1555394196, rs1566891454, rs1566891406, rs1566891404, rs1566895262, rs1566891645, rs1566895225, rs1566896114, rs1566898399, rs1566904011, rs1566906537, rs1566908956, rs1566909766, rs1566919599, rs1566937712, rs1566915335, rs1566891675, rs1566904526, rs1566906506, rs1566900540, rs1566894230, rs1555395206, rs1566891797, rs1597512576, rs1597523873, rs1597581001, rs1597516325, rs1057524757, rs1597506641, rs1597520781, rs1597593695, rs1597529829, rs1597520625, rs1597579923, rs1597531796, rs1008275504, rs1597567249, rs1597569265, rs1597652471, rs1597516347, rs1597577114, rs1597633163, rs1597519658, rs1597593852, rs1597516501, rs1566913982, rs1555393859, rs1597513708, rs368978109, rs1480832655, rs1597520683, rs1597522390, rs1597522553, rs1597529748, rs1597533707, rs1597537815, rs1597545309, rs1597545836, rs1597563234, rs1597563280, rs1597564359, rs772108557, rs1597568968, rs1597574236, rs1597574308, rs1597577975, rs193922179, rs1597581005, rs1597593736, rs1597623670, rs1597625734, rs1597631662, rs113604459, rs1597633183, rs1597633219, rs1597518951, rs1555394781, rs1597525871, rs1597526073, rs1597569159, rs1597569536, rs1597563934, rs1597545199, rs1364210063, rs1597552583, rs1597520619, rs1597540854, rs1597591602, rs1597569551, rs1597548716, rs1597553721, rs112728248, rs1597537858, rs1597517935, rs1597540907, rs1597552388, rs1597591643, rs1597529841, rs1597506547, rs1597509836, rs1597529686, rs1566897404, rs1597533713, rs1597543486, rs1597545257, rs1597545345, rs1597548672, rs1597562812, rs1597563287, rs1597571391, rs1555400052, rs1597583989, rs363852, rs1597547226, rs363808, rs974604498, rs2043595650, rs2043526284, rs2042997306, rs1555397195, rs886039054, rs1555397213, rs2042873946	23289900

Unknown
Disease name	Disease term	dbSNP ID	References
Mammary neoplasms	Mammary Neoplasms, Human, Mammary Neoplasms		23289900
Liver carcinoma	Liver carcinoma		19514085
Senile dementia	Presenile dementia, Acute Confusional Senile Dementia		30820047