Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
94103 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
ORMDL sphingolipid biosynthesis regulator 3 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
ORMDL3 |
SynonymsGene synonyms aliases
|
- |
ChromosomeChromosome number
|
17 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
17q21.1 |
miRNAmiRNA information provided by mirtarbase database.
|
|
Transcription factors
|
Transcription factor |
Regulation |
Reference |
STAT6 |
Unknown |
23461825 |
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q8N138 |
Protein name |
ORM1-like protein 3 |
Protein function |
Plays an essential role in the homeostatic regulation of sphingolipid de novo biosynthesis by modulating the activity of the serine palmitoyltransferase (SPT) in response to ceramide levels (PubMed:20182505, PubMed:30700557, PubMed:37308477). Wh |
PDB |
6M4N
,
6M4O
,
7CQI
,
7CQK
,
7K0M
,
7K0N
,
7K0O
,
7K0P
,
7K0Q
,
7YIU
,
7YIY
,
7YJ1
,
7YJ2
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF04061 |
ORMDL |
11 → 146 |
ORMDL family |
Family |
|
Sequence |
|
Sequence length |
153 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
|
|
Associated diseases
|
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Biliary cirrhosis |
Primary biliary cirrhosis |
|
22961000 |
Ulcerative colitis |
Ulcerative Colitis |
|
20228799 |
|