SFXN5 (sideroflexin 5)

Gene

• Entrez ID: 94097
• Gene name: Sideroflexin 5
• Gene symbol: SFXN5
• Synonyms: BBG-TCC, SLC56A5
• Chromosome: 2
• Chromosome location: 2p13.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020184	hsa-miR-130b-3p	Sequencing	20371350
MIRT028019	hsa-miR-93-5p	Sequencing	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	20371350
MIRT554362	hsa-miR-137	PAR-CLIP	20371350
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT554358	hsa-miR-4801	PAR-CLIP	20371350
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT554357	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT554355	hsa-miR-3941	PAR-CLIP	20371350
MIRT554356	hsa-miR-4672	PAR-CLIP	20371350
MIRT554354	hsa-miR-466	PAR-CLIP	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	20371350
MIRT554362	hsa-miR-137	PAR-CLIP	20371350
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT554358	hsa-miR-4801	PAR-CLIP	20371350
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT554357	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT554355	hsa-miR-3941	PAR-CLIP	20371350
MIRT554356	hsa-miR-4672	PAR-CLIP	20371350
MIRT554354	hsa-miR-466	PAR-CLIP	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	21572407
MIRT554362	hsa-miR-137	PAR-CLIP	21572407
MIRT554361	hsa-miR-605-5p	PAR-CLIP	21572407
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	21572407
MIRT554358	hsa-miR-4801	PAR-CLIP	21572407
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT554357	hsa-miR-186-3p	PAR-CLIP	21572407
MIRT554355	hsa-miR-3941	PAR-CLIP	21572407
MIRT554356	hsa-miR-4672	PAR-CLIP	21572407
MIRT554354	hsa-miR-466	PAR-CLIP	21572407
MIRT554363	hsa-miR-496	PAR-CLIP	20371350
MIRT554362	hsa-miR-137	PAR-CLIP	20371350
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT554358	hsa-miR-4801	PAR-CLIP	20371350
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT554357	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT554355	hsa-miR-3941	PAR-CLIP	20371350
MIRT554356	hsa-miR-4672	PAR-CLIP	20371350
MIRT554354	hsa-miR-466	PAR-CLIP	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	20371350
MIRT554362	hsa-miR-137	PAR-CLIP	20371350
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT554358	hsa-miR-4801	PAR-CLIP	20371350
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT554357	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT554355	hsa-miR-3941	PAR-CLIP	20371350
MIRT554356	hsa-miR-4672	PAR-CLIP	20371350
MIRT554354	hsa-miR-466	PAR-CLIP	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	21572407
MIRT554362	hsa-miR-137	PAR-CLIP	21572407
MIRT554361	hsa-miR-605-5p	PAR-CLIP	21572407
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	21572407
MIRT554358	hsa-miR-4801	PAR-CLIP	21572407
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT554357	hsa-miR-186-3p	PAR-CLIP	21572407
MIRT554355	hsa-miR-3941	PAR-CLIP	21572407
MIRT554356	hsa-miR-4672	PAR-CLIP	21572407
MIRT554354	hsa-miR-466	PAR-CLIP	21572407
MIRT1342693	hsa-miR-1	CLIP-seq
MIRT1342694	hsa-miR-106a	CLIP-seq
MIRT1342695	hsa-miR-106b	CLIP-seq
MIRT1342696	hsa-miR-1184	CLIP-seq
MIRT1342697	hsa-miR-1205	CLIP-seq
MIRT1342698	hsa-miR-1224-5p	CLIP-seq
MIRT1342699	hsa-miR-1237	CLIP-seq
MIRT1342700	hsa-miR-1245b-5p	CLIP-seq
MIRT1342701	hsa-miR-125a-5p	CLIP-seq
MIRT1342702	hsa-miR-125b	CLIP-seq
MIRT1342703	hsa-miR-1273f	CLIP-seq
MIRT1342704	hsa-miR-127-5p	CLIP-seq
MIRT1342705	hsa-miR-1287	CLIP-seq
MIRT1342706	hsa-miR-1289	CLIP-seq
MIRT1342707	hsa-miR-1292	CLIP-seq
MIRT1342708	hsa-miR-1299	CLIP-seq
MIRT1342709	hsa-miR-1301	CLIP-seq
MIRT1342710	hsa-miR-142-5p	CLIP-seq
MIRT1342711	hsa-miR-15a	CLIP-seq
MIRT1342712	hsa-miR-15b	CLIP-seq
MIRT1342713	hsa-miR-16	CLIP-seq
MIRT1342714	hsa-miR-17	CLIP-seq
MIRT1342715	hsa-miR-195	CLIP-seq
MIRT1342716	hsa-miR-206	CLIP-seq
MIRT1342717	hsa-miR-20a	CLIP-seq
MIRT1342718	hsa-miR-20b	CLIP-seq
MIRT1342719	hsa-miR-218	CLIP-seq
MIRT1342720	hsa-miR-23a	CLIP-seq
MIRT1342721	hsa-miR-23b	CLIP-seq
MIRT1342722	hsa-miR-23c	CLIP-seq
MIRT1342723	hsa-miR-24	CLIP-seq
MIRT1342724	hsa-miR-2467-5p	CLIP-seq
MIRT1342725	hsa-miR-299-3p	CLIP-seq
MIRT1342726	hsa-miR-3135b	CLIP-seq
MIRT1342727	hsa-miR-3142	CLIP-seq
MIRT1342728	hsa-miR-3158-5p	CLIP-seq
MIRT1342729	hsa-miR-3179	CLIP-seq
MIRT1342730	hsa-miR-3188	CLIP-seq
MIRT1342731	hsa-miR-3198	CLIP-seq
MIRT1342732	hsa-miR-3201	CLIP-seq
MIRT1342733	hsa-miR-3609	CLIP-seq
MIRT1342734	hsa-miR-3613-3p	CLIP-seq
MIRT1342735	hsa-miR-3622a-3p	CLIP-seq
MIRT1342736	hsa-miR-3622b-3p	CLIP-seq
MIRT1342737	hsa-miR-3667-5p	CLIP-seq
MIRT1342738	hsa-miR-3673	CLIP-seq
MIRT1342739	hsa-miR-371b-5p	CLIP-seq
MIRT1342740	hsa-miR-377	CLIP-seq
MIRT1342741	hsa-miR-3922-5p	CLIP-seq
MIRT1342742	hsa-miR-3938	CLIP-seq
MIRT1342743	hsa-miR-3975	CLIP-seq
MIRT1342744	hsa-miR-424	CLIP-seq
MIRT1342745	hsa-miR-4252	CLIP-seq
MIRT1342746	hsa-miR-4265	CLIP-seq
MIRT1342747	hsa-miR-4274	CLIP-seq
MIRT1342748	hsa-miR-4284	CLIP-seq
MIRT1342749	hsa-miR-4292	CLIP-seq
MIRT1342750	hsa-miR-4294	CLIP-seq
MIRT1342751	hsa-miR-4296	CLIP-seq
MIRT1342752	hsa-miR-4300	CLIP-seq
MIRT1342753	hsa-miR-4308	CLIP-seq
MIRT1342754	hsa-miR-4309	CLIP-seq
MIRT1342755	hsa-miR-431	CLIP-seq
MIRT1342756	hsa-miR-4319	CLIP-seq
MIRT1342757	hsa-miR-4322	CLIP-seq
MIRT1342758	hsa-miR-4325	CLIP-seq
MIRT1342759	hsa-miR-4417	CLIP-seq
MIRT1342760	hsa-miR-4457	CLIP-seq
MIRT1342761	hsa-miR-4468	CLIP-seq
MIRT1342762	hsa-miR-4471	CLIP-seq
MIRT1342763	hsa-miR-4530	CLIP-seq
MIRT1342764	hsa-miR-4635	CLIP-seq
MIRT1342765	hsa-miR-4639-3p	CLIP-seq
MIRT1342766	hsa-miR-4640-5p	CLIP-seq
MIRT1342767	hsa-miR-4649-3p	CLIP-seq
MIRT1342768	hsa-miR-4654	CLIP-seq
MIRT1342769	hsa-miR-4660	CLIP-seq
MIRT1342770	hsa-miR-4663	CLIP-seq
MIRT1342771	hsa-miR-4676-5p	CLIP-seq
MIRT1342772	hsa-miR-4704-3p	CLIP-seq
MIRT1342773	hsa-miR-4706	CLIP-seq
MIRT1342774	hsa-miR-4708-3p	CLIP-seq
MIRT1342775	hsa-miR-4709-3p	CLIP-seq
MIRT1342776	hsa-miR-4716-3p	CLIP-seq
MIRT1342777	hsa-miR-4720-5p	CLIP-seq
MIRT1342778	hsa-miR-4726-5p	CLIP-seq
MIRT1342779	hsa-miR-4732-3p	CLIP-seq
MIRT1342780	hsa-miR-4749-5p	CLIP-seq
MIRT1342781	hsa-miR-4751	CLIP-seq
MIRT1342782	hsa-miR-4753-5p	CLIP-seq
MIRT1342783	hsa-miR-4755-3p	CLIP-seq
MIRT1342784	hsa-miR-4764-5p	CLIP-seq
MIRT1342785	hsa-miR-4769-5p	CLIP-seq
MIRT1342786	hsa-miR-4789-3p	CLIP-seq
MIRT1342787	hsa-miR-4791	CLIP-seq
MIRT1342788	hsa-miR-4793-5p	CLIP-seq
MIRT1342789	hsa-miR-4796-3p	CLIP-seq
MIRT1342790	hsa-miR-4799-3p	CLIP-seq
MIRT1342791	hsa-miR-4802-5p	CLIP-seq
MIRT1342792	hsa-miR-485-5p	CLIP-seq
MIRT1342793	hsa-miR-497	CLIP-seq
MIRT1342794	hsa-miR-5047	CLIP-seq
MIRT1342795	hsa-miR-519a	CLIP-seq
MIRT1342796	hsa-miR-519b-3p	CLIP-seq
MIRT1342797	hsa-miR-519c-3p	CLIP-seq
MIRT1342798	hsa-miR-519d	CLIP-seq
MIRT1342799	hsa-miR-541	CLIP-seq
MIRT1342800	hsa-miR-544b	CLIP-seq
MIRT1342801	hsa-miR-548ah	CLIP-seq
MIRT1342802	hsa-miR-575	CLIP-seq
MIRT1342803	hsa-miR-577	CLIP-seq
MIRT1342804	hsa-miR-584	CLIP-seq
MIRT1342805	hsa-miR-613	CLIP-seq
MIRT1342806	hsa-miR-654-5p	CLIP-seq
MIRT1342807	hsa-miR-670	CLIP-seq
MIRT1342808	hsa-miR-744	CLIP-seq
MIRT1342809	hsa-miR-765	CLIP-seq
MIRT1342810	hsa-miR-875-3p	CLIP-seq
MIRT1342811	hsa-miR-920	CLIP-seq
MIRT1342812	hsa-miR-93	CLIP-seq
MIRT1342813	hsa-miR-935	CLIP-seq
MIRT2101328	hsa-miR-125a-3p	CLIP-seq
MIRT1342703	hsa-miR-1273f	CLIP-seq
MIRT2101329	hsa-miR-129-5p	CLIP-seq
MIRT2101330	hsa-miR-2115	CLIP-seq
MIRT1342720	hsa-miR-23a	CLIP-seq
MIRT1342721	hsa-miR-23b	CLIP-seq
MIRT1342722	hsa-miR-23c	CLIP-seq
MIRT1342723	hsa-miR-24	CLIP-seq
MIRT2101331	hsa-miR-3074-5p	CLIP-seq
MIRT2101332	hsa-miR-3152-3p	CLIP-seq
MIRT2101333	hsa-miR-338-3p	CLIP-seq
MIRT2101334	hsa-miR-3591-5p	CLIP-seq
MIRT2101335	hsa-miR-3606	CLIP-seq
MIRT1342734	hsa-miR-3613-3p	CLIP-seq
MIRT2101336	hsa-miR-3689a-3p	CLIP-seq
MIRT2101337	hsa-miR-3689c	CLIP-seq
MIRT1342739	hsa-miR-371b-5p	CLIP-seq
MIRT2101338	hsa-miR-3913-3p	CLIP-seq
MIRT2101339	hsa-miR-3918	CLIP-seq
MIRT2101340	hsa-miR-3936	CLIP-seq
MIRT2101341	hsa-miR-4267	CLIP-seq
MIRT1342748	hsa-miR-4284	CLIP-seq
MIRT1342752	hsa-miR-4300	CLIP-seq
MIRT2101342	hsa-miR-4431	CLIP-seq
MIRT1342768	hsa-miR-4654	CLIP-seq
MIRT2101343	hsa-miR-4685-5p	CLIP-seq
MIRT2101344	hsa-miR-4722-3p	CLIP-seq
MIRT2101345	hsa-miR-4757-5p	CLIP-seq
MIRT1342785	hsa-miR-4769-5p	CLIP-seq
MIRT2101346	hsa-miR-488	CLIP-seq
MIRT2101347	hsa-miR-489	CLIP-seq
MIRT2101348	hsa-miR-516a-3p	CLIP-seq
MIRT1342799	hsa-miR-541	CLIP-seq
MIRT2101349	hsa-miR-542-3p	CLIP-seq
MIRT1342804	hsa-miR-584	CLIP-seq
MIRT2101350	hsa-miR-615-5p	CLIP-seq
MIRT1342806	hsa-miR-654-5p	CLIP-seq
MIRT1342811	hsa-miR-920	CLIP-seq
MIRT2101351	hsa-miR-921	CLIP-seq
MIRT1342693	hsa-miR-1	CLIP-seq
MIRT1342696	hsa-miR-1184	CLIP-seq
MIRT1342697	hsa-miR-1205	CLIP-seq
MIRT2325718	hsa-miR-1254	CLIP-seq
MIRT1342708	hsa-miR-1299	CLIP-seq
MIRT1342709	hsa-miR-1301	CLIP-seq
MIRT2325719	hsa-miR-1305	CLIP-seq
MIRT2325720	hsa-miR-133a	CLIP-seq
MIRT2325721	hsa-miR-133b	CLIP-seq
MIRT2325722	hsa-miR-1587	CLIP-seq
MIRT2325723	hsa-miR-1912	CLIP-seq
MIRT2325724	hsa-miR-1972	CLIP-seq
MIRT1342716	hsa-miR-206	CLIP-seq
MIRT1342720	hsa-miR-23a	CLIP-seq
MIRT1342721	hsa-miR-23b	CLIP-seq
MIRT1342722	hsa-miR-23c	CLIP-seq
MIRT1342723	hsa-miR-24	CLIP-seq
MIRT2325725	hsa-miR-3116	CLIP-seq
MIRT2325726	hsa-miR-3126-5p	CLIP-seq
MIRT1342728	hsa-miR-3158-5p	CLIP-seq
MIRT2325727	hsa-miR-3199	CLIP-seq
MIRT2325728	hsa-miR-3202	CLIP-seq
MIRT1342734	hsa-miR-3613-3p	CLIP-seq
MIRT2325729	hsa-miR-3665	CLIP-seq
MIRT1342738	hsa-miR-3673	CLIP-seq
MIRT1342739	hsa-miR-371b-5p	CLIP-seq
MIRT2325730	hsa-miR-4253	CLIP-seq
MIRT2325731	hsa-miR-4281	CLIP-seq
MIRT1342748	hsa-miR-4284	CLIP-seq
MIRT2325732	hsa-miR-4287	CLIP-seq
MIRT1342749	hsa-miR-4292	CLIP-seq
MIRT2325733	hsa-miR-4480	CLIP-seq
MIRT2325734	hsa-miR-4492	CLIP-seq
MIRT2325735	hsa-miR-4498	CLIP-seq
MIRT2325736	hsa-miR-4515	CLIP-seq
MIRT1342765	hsa-miR-4639-3p	CLIP-seq
MIRT2325737	hsa-miR-4645-5p	CLIP-seq
MIRT2325738	hsa-miR-4650-5p	CLIP-seq
MIRT1342768	hsa-miR-4654	CLIP-seq
MIRT2325739	hsa-miR-4656	CLIP-seq
MIRT1342769	hsa-miR-4660	CLIP-seq
MIRT2325740	hsa-miR-4671-5p	CLIP-seq
MIRT2325741	hsa-miR-4673	CLIP-seq
MIRT2325742	hsa-miR-4675	CLIP-seq
MIRT2325743	hsa-miR-4685-3p	CLIP-seq
MIRT2325744	hsa-miR-4690-3p	CLIP-seq
MIRT2101344	hsa-miR-4722-3p	CLIP-seq
MIRT2325745	hsa-miR-4731-5p	CLIP-seq
MIRT2325746	hsa-miR-4741	CLIP-seq
MIRT2101345	hsa-miR-4757-5p	CLIP-seq
MIRT1342785	hsa-miR-4769-5p	CLIP-seq
MIRT1342786	hsa-miR-4789-3p	CLIP-seq
MIRT2325747	hsa-miR-486-3p	CLIP-seq
MIRT1342794	hsa-miR-5047	CLIP-seq
MIRT1342795	hsa-miR-519a	CLIP-seq
MIRT1342796	hsa-miR-519b-3p	CLIP-seq
MIRT1342797	hsa-miR-519c-3p	CLIP-seq
MIRT1342799	hsa-miR-541	CLIP-seq
MIRT2325748	hsa-miR-544	CLIP-seq
MIRT1342800	hsa-miR-544b	CLIP-seq
MIRT2325749	hsa-miR-551a	CLIP-seq
MIRT2325750	hsa-miR-551b	CLIP-seq
MIRT1342804	hsa-miR-584	CLIP-seq
MIRT2325751	hsa-miR-607	CLIP-seq
MIRT1342805	hsa-miR-613	CLIP-seq
MIRT1342806	hsa-miR-654-5p	CLIP-seq
MIRT2325752	hsa-miR-657	CLIP-seq
MIRT2325753	hsa-miR-762	CLIP-seq
MIRT1342810	hsa-miR-875-3p	CLIP-seq
MIRT2101350	hsa-miR-615-5p	CLIP-seq
MIRT1342699	hsa-miR-1237	CLIP-seq
MIRT1342700	hsa-miR-1245b-5p	CLIP-seq
MIRT1342703	hsa-miR-1273f	CLIP-seq
MIRT1342711	hsa-miR-15a	CLIP-seq
MIRT1342712	hsa-miR-15b	CLIP-seq
MIRT1342713	hsa-miR-16	CLIP-seq
MIRT1342715	hsa-miR-195	CLIP-seq
MIRT1342727	hsa-miR-3142	CLIP-seq
MIRT1342741	hsa-miR-3922-5p	CLIP-seq
MIRT1342744	hsa-miR-424	CLIP-seq
MIRT1342752	hsa-miR-4300	CLIP-seq
MIRT1342763	hsa-miR-4530	CLIP-seq
MIRT1342767	hsa-miR-4649-3p	CLIP-seq
MIRT1342770	hsa-miR-4663	CLIP-seq
MIRT1342774	hsa-miR-4708-3p	CLIP-seq
MIRT1342793	hsa-miR-497	CLIP-seq
MIRT1342811	hsa-miR-920	CLIP-seq
MIRT1342699	hsa-miR-1237	CLIP-seq
MIRT1342700	hsa-miR-1245b-5p	CLIP-seq
MIRT1342727	hsa-miR-3142	CLIP-seq
MIRT1342741	hsa-miR-3922-5p	CLIP-seq
MIRT1342767	hsa-miR-4649-3p	CLIP-seq
MIRT1342770	hsa-miR-4663	CLIP-seq
MIRT1342774	hsa-miR-4708-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005739	Component	Mitochondrion	IDA	30442778
GO:0006865	Process	Amino acid transport	IEA
GO:0015137	Function	Citrate transmembrane transporter activity	IBA	21873635
GO:0015746	Process	Citrate transport	IBA	21873635
GO:0022857	Function	Transmembrane transporter activity	IBA	21873635
GO:0031305	Component	Integral component of mitochondrial inner membrane	IBA	21873635
GO:0034220	Process	Ion transmembrane transport	IEA
GO:1990542	Process	Mitochondrial transmembrane transport	IBA	21873635

Other IDs

• MIM: 615572
• HGNC: 16073
• e!Ensembl: ENSG00000144040

Protein

• UniProt ID: Q8TD22
• Protein name: Sideroflexin-5
• Protein function: Mitochondrial amino-acid transporter (By similarity). Transports citrate (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity) (PubMed:30442778). In brown adipose tissue,
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03820	SFXNs	26 → 340	Sideroflexins	Family

• Sequence:

  MADTATTASAAAASAASASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERRL
  REAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIV
  VGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVG
  LNVLVQKANKFTPATRLLIQRFVPFPAVASANICNVVLMRYGELEEGIDVLDSDGNLVGS
  SKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVQSLVCLAAFG
  LALPLAISLFPQMSEIETSQLEPEIAQATSSRTVVYNKGL

• Sequence length: 340

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	30285260