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FBXO44 (F-box protein 44)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
93611
Gene nameGene Name - the full gene name approved by the HGNC.
F-box protein 44
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
FBXO44
SynonymsGene synonyms aliases
FBG3, FBX30, FBX6A, Fbx44, Fbxo6a
ChromosomeChromosome number
1
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p36.22
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT043340 hsa-miR-331-3p CLASH 23622248
MIRT658207 hsa-miR-1306-5p HITS-CLIP 23824327
MIRT658206 hsa-miR-129-1-3p HITS-CLIP 23824327
MIRT658205 hsa-miR-129-2-3p HITS-CLIP 23824327
MIRT658204 hsa-miR-6765-3p HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000209 Process Protein polyubiquitination TAS
GO:0005515 Function Protein binding IPI 18203720, 19159283, 25416956, 27705803
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005829 Component Cytosol TAS
GO:0006516 Process Glycoprotein catabolic process IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9H4M3
Protein name F-box only protein 44 (F-box protein FBX30) (F-box/G-domain protein 3)
Protein function Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
PDB 3WSO , 5B4N
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12937 F-box-like
6 53
F-box-like
Domain
PF04300 FBA
72 250
F-box associated region
Family
Sequence
Sequence length 255
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17199135
Unknown
Disease name Disease term dbSNP ID References
Sclerocystic ovaries Sclerocystic Ovaries 21411543
Polycystic ovary syndrome Polycystic Ovary Syndrome 21411543
Prostatic neoplasms Prostatic Neoplasms 17199135

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