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SYNGR1 (synaptogyrin 1)
Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9145
Gene nameGene Name - the full gene name approved by the HGNC.
Synaptogyrin 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SYNGR1
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
22
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q13.1
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being re
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT024495 hsa-miR-215-5p Microarray 19074876
MIRT026210 hsa-miR-192-5p Microarray 19074876
MIRT036022 hsa-miR-1301-3p CLASH 23622248
MIRT652943 hsa-miR-4759 HITS-CLIP 23824327
MIRT652944 hsa-miR-3169 HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956
GO:0005886 Component Plasma membrane TAS
GO:0006605 Process Protein targeting IEA
GO:0030285 Component Integral component of synaptic vesicle membrane IEA
GO:0030672 Component Synaptic vesicle membrane IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID O43759
Protein name Synaptogyrin-1
Protein function May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the re
PDB 8A6M
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01284 MARVEL
20 → 167
Membrane-associating domain
 Domain
Sequence
Sequence length 233
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
 
Reactome
    Neutrophil degranulation
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute, Acute Myeloid Leukemia (AML-M2) rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601 17330099
Rheumatoid arthritis Rheumatoid Arthritis rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212 24390342, 30423114, 24532676
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 16215643, 14732601, 17049558, 19665806, 19641478
Unknown
Disease name Disease term dbSNP ID References
Bipolar disorder Bipolar Disorder 16215643, 19665806
Lupus erythematosus Lupus Erythematosus, Systemic 26808113
Myeloid leukemia Acute Myeloid Leukemia, M1 17330099
Nonbacterial verrucal endocardiosis Libman-Sacks Disease 26808113

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