Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
9093 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
DnaJ heat shock protein family (Hsp40) member A3 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
DNAJA3 |
SynonymsGene synonyms aliases
|
HCA57, TID1, Tid1-L, Tid1-S, hTID-1 |
ChromosomeChromosome number
|
16 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
16p13.3 |
SummarySummary of gene provided in NCBI Entrez Gene.
|
This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized t |
miRNAmiRNA information provided by mirtarbase database.
|
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q96EY1 |
Protein name |
DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog) |
Protein function |
Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by |
PDB |
2CTT
,
2DN9
,
6IWS
,
7X89
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00226 |
DnaJ |
93 → 155 |
DnaJ domain |
Domain |
PF01556 |
DnaJ_C |
209 → 413 |
DnaJ C terminal domain |
Domain |
PF00684 |
DnaJ_CXXCXGXG |
236 → 302 |
DnaJ central domain |
Domain |
|
Sequence |
|
Sequence length |
480 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
|
|
Associated diseases
|
Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Schizophrenia |
Schizophrenia |
rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 |
26198764 |
|