GediPNet logo

SLC7A6 (solute carrier family 7 member 6)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9057
Gene nameGene Name - the full gene name approved by the HGNC.
Solute carrier family 7 member 6
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SLC7A6
SynonymsGene synonyms aliases
LAT-2, LAT3, y+LAT-2
ChromosomeChromosome number
16
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16q22.1
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001761 hsa-miR-30a-3p Luciferase reporter assay, qRT-PCR, Western blot 16239240
MIRT004987 hsa-miR-125b-5p Microarray 17891175
MIRT020026 hsa-miR-375 Microarray 20215506
MIRT027832 hsa-miR-98-5p Microarray 19088304
MIRT001761 hsa-miR-30a-3p qRT-PCR 16239240
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003333 Process Amino acid transmembrane transport IBA 21873635
GO:0003333 Process Amino acid transmembrane transport TAS 9829974
GO:0005515 Function Protein binding IPI 32296183
GO:0005886 Component Plasma membrane IDA
GO:0005886 Component Plasma membrane TAS
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q92536
Protein name Y+L amino acid transporter 2 (Cationic amino acid transporter, y+ system) (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2)
Protein function Heterodimer with SLC3A2, that functions as an antiporter which operates as an efflux route by exporting cationic amino acids such as L-arginine from inside the cells in exchange with neutral amino acids like L-leucine, L-glutamine and isoleucine
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13520 AA_permease_2
45 468
Amino acid permease
Family
Sequence
Sequence length 515
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Basigin interactions
Amino acid transport across the plasma membrane
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 28991256, 30285260

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412