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CCNG2 (cyclin G2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
901
Gene nameGene Name - the full gene name approved by the HGNC.
Cyclin G2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CCNG2
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
4
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q21.1
SummarySummary of gene provided in NCBI Entrez Gene.
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of abou
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016825 hsa-miR-335-5p Microarray 18185580
MIRT027966 hsa-miR-93-5p Sequencing 20371350
MIRT041104 hsa-miR-503-5p CLASH 23622248
MIRT737381 hsa-miR-1246 Western blotting, Immunohistochemistry (IHC), qRT-PCR 32196930
MIRT872060 hsa-let-7a CLIP-seq
Transcription factors
Transcription factor Regulation Reference
AHR Activation 22596188
FOXA1 Unknown 22596188
OTX2 Activation 21047732
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000079 Process Regulation of cyclin-dependent protein serine/threonine kinase activity IBA 21873635
GO:0000307 Component Cyclin-dependent protein kinase holoenzyme complex IBA 21873635
GO:0005634 Component Nucleus IBA 21873635
GO:0005737 Component Cytoplasm IBA 21873635
GO:0016538 Function Cyclin-dependent protein serine/threonine kinase regulator activity IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q16589
Protein name Cyclin-G2
Protein function May play a role in growth regulation and in negative regulation of cell cycle progression.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00134 Cyclin_N
20 154
Cyclin, N-terminal domain
Domain
Sequence
MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV
EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP
STHDVIRISQCKCTASDIKRMEKIISEKLHYELE
ATTALNFLHLYHTIILCHTSERKEIL
SLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTE
FFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCFD
ESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS
Sequence length 344
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
  FoxO signaling pathway
p53 signaling pathway
 
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Rheumatoid arthritis Rheumatoid Arthritis rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212 22491018

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