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CCNG1 (cyclin G1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
900
Gene nameGene Name - the full gene name approved by the HGNC.
Cyclin G1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CCNG1
SynonymsGene synonyms aliases
CCNG
ChromosomeChromosome number
5
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q34
SummarySummary of gene provided in NCBI Entrez Gene.
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded prote
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT003006 hsa-miR-122-5p Reporter assay 17616664
MIRT003006 hsa-miR-122-5p Western blot 19584283
MIRT006782 hsa-miR-9-5p Luciferase reporter assay, Microarray, qRT-PCR, Western blot 22761433
MIRT003006 hsa-miR-122-5p qRT-PCR 23126531
MIRT006782 hsa-miR-9-5p Microarray 17612493
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000079 Process Regulation of cyclin-dependent protein serine/threonine kinase activity IBA 21873635
GO:0000307 Component Cyclin-dependent protein kinase holoenzyme complex IBA 21873635
GO:0005515 Function Protein binding IPI 17245430, 21516116, 21988832, 25416956, 28330616, 31515488, 32296183, 32814053
GO:0005634 Component Nucleus IBA 21873635
GO:0005654 Component Nucleoplasm TAS
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P51959
Protein name Cyclin-G1 (Cyclin-G)
Protein function May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00134 Cyclin_N
16 150
Cyclin, N-terminal domain
Domain
Sequence
MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL
SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD
LIRISQYRFTVSDLMRMEKIVLEKVCWKVK
ATTAFQFLQLYYSLLQENLPLERRNSINFE
RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF
WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
Sequence length 295
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
Reactome
  p53 signaling pathway
MicroRNAs in cancer
  Regulation of TP53 Degradation
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 16289808
Unknown
Disease name Disease term dbSNP ID References
Lung neoplasms Lung Neoplasms 16289808

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