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CPNE3 (copine 3)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8895
Gene nameGene Name - the full gene name approved by the HGNC.
Copine 3
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CPNE3
SynonymsGene synonyms aliases
CPN3, PRO1071
ChromosomeChromosome number
8
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8q21.3
SummarySummary of gene provided in NCBI Entrez Gene.
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a protein which contains two type II C2 domains in the amino-terminus and an A domain-like sequence in the car
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT002575 hsa-miR-124-3p Microarray 15685193
MIRT007128 hsa-miR-133b Luciferase reporter assay 23451058
MIRT002575 hsa-miR-124-3p Microarray;Other 15685193
MIRT052920 hsa-miR-451a Luciferase reporter assay, qRT-PCR, Western blot 24574214
MIRT052920 hsa-miR-451a Luciferase reporter assay, qRT-PCR, Western blot 24574214
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674
GO:0004674 Function Protein serine/threonine kinase activity IDA 11041869
GO:0005515 Function Protein binding IPI 20010870, 21044950
GO:0005544 Function Calcium-dependent phospholipid binding IBA 21873635
GO:0005544 Function Calcium-dependent phospholipid binding IDA 9430674, 20010870
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID O75131
Protein name Copine-3 (Copine III)
Protein function Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation (PubMed:20010870).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00168 C2
8 116
C2 domain
Domain
PF00168 C2
138 249
C2 domain
Domain
PF07002 Copine
310 527
Copine
Family
Sequence
Sequence length 537
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Glycerophospholipid biosynthesis
Neutrophil degranulation
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 18264096
Unknown
Disease name Disease term dbSNP ID References
Prostatic neoplasms Prostatic Neoplasms 18264096

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