Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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8880 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Far upstream element binding protein 1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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FUBP1 |
SynonymsGene synonyms aliases
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FBP, FUBP, hDH V |
ChromosomeChromosome number
|
1 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p31.1 |
SummarySummary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the re |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q96AE4 |
Protein name |
Far upstream element-binding protein 1 (FBP) (FUSE-binding protein 1) (DNA helicase V) (hDH V) |
Protein function |
Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription. |
PDB |
1J4W
,
2KXH
,
4LIJ
,
6Y24
,
6Y2C
,
6Y2D
,
8P25
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00013 |
KH_1 |
102 → 166 |
KH domain |
Domain |
PF00013 |
KH_1 |
187 → 253 |
KH domain |
Domain |
PF00013 |
KH_1 |
277 → 341 |
KH domain |
Domain |
PF00013 |
KH_1 |
378 → 445 |
KH domain |
Domain |
PF09005 |
DUF1897 |
572 → 599 |
Domain of unknown function (DUF1897) |
Domain |
PF09005 |
DUF1897 |
602 → 626 |
Domain of unknown function (DUF1897) |
Domain |
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Sequence |
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Sequence length |
644 |
Interactions |
View interactions |
Associated diseases
|
Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Glioma |
Glioma |
rs121909219, rs121909224, rs587776667, rs587776671, rs121909239, rs121909241, rs28933368, rs121913500, rs55863639, rs786201995, rs786202517, rs786201044, rs398123317, rs1057518425, rs121913499, rs1060500122, rs781647403, rs1060500126, rs1554897889, rs1114167629, rs1114167656, rs587782603, rs1554893824, rs1554900615, rs1564568660, rs786204900, rs762518389, rs1339631701 |
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