ALDH1A2 (aldehyde dehydrogenase 1 family member A2)

Gene

• Entrez ID: 8854
• Gene name: Aldehyde dehydrogenase 1 family member A2
• Gene symbol: ALDH1A2
• Synonyms: DIH4, RALDH(II), RALDH2, RALDH2-T
• Chromosome: 15
• Chromosome location: 15q21.3
• Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020672	hsa-miR-155-5p	Proteomics	18668040
MIRT047601	hsa-miR-10a-5p	CLASH	23622248
MIRT047601	hsa-miR-10a-5p	CLASH	23622248
MIRT041305	hsa-miR-193b-3p	CLASH	23622248
MIRT039966	hsa-miR-615-3p	CLASH	23622248
MIRT650255	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT632090	hsa-miR-5002-5p	HITS-CLIP	23824327
MIRT632089	hsa-miR-16-2-3p	HITS-CLIP	23824327
MIRT632088	hsa-miR-195-3p	HITS-CLIP	23824327
MIRT632087	hsa-miR-4301	HITS-CLIP	23824327
MIRT632086	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT632079	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT632078	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT632074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT632090	hsa-miR-5002-5p	HITS-CLIP	23824327
MIRT632089	hsa-miR-16-2-3p	HITS-CLIP	23824327
MIRT632088	hsa-miR-195-3p	HITS-CLIP	23824327
MIRT632087	hsa-miR-4301	HITS-CLIP	23824327
MIRT632086	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT632085	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT632084	hsa-miR-5193	HITS-CLIP	23824327
MIRT632083	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT632082	hsa-miR-4287	HITS-CLIP	23824327
MIRT632081	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT281547	hsa-miR-621	HITS-CLIP	23824327
MIRT632080	hsa-miR-4268	HITS-CLIP	23824327
MIRT632079	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT632078	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT632077	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT632076	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT632075	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT632074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT650255	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT632090	hsa-miR-5002-5p	HITS-CLIP	23824327
MIRT632089	hsa-miR-16-2-3p	HITS-CLIP	23824327
MIRT632088	hsa-miR-195-3p	HITS-CLIP	23824327
MIRT632087	hsa-miR-4301	HITS-CLIP	23824327
MIRT632086	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT632079	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT632078	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT632074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT632090	hsa-miR-5002-5p	HITS-CLIP	23824327
MIRT632089	hsa-miR-16-2-3p	HITS-CLIP	23824327
MIRT632088	hsa-miR-195-3p	HITS-CLIP	23824327
MIRT632087	hsa-miR-4301	HITS-CLIP	23824327
MIRT632086	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT632085	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT632084	hsa-miR-5193	HITS-CLIP	23824327
MIRT632083	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT632082	hsa-miR-4287	HITS-CLIP	23824327
MIRT632081	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT281547	hsa-miR-621	HITS-CLIP	23824327
MIRT632080	hsa-miR-4268	HITS-CLIP	23824327
MIRT632079	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT632078	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT632077	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT632076	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT632075	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT632074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT776947	hsa-miR-1254	CLIP-seq
MIRT776948	hsa-miR-137	CLIP-seq
MIRT776949	hsa-miR-24	CLIP-seq
MIRT776950	hsa-miR-3116	CLIP-seq
MIRT776951	hsa-miR-3176	CLIP-seq
MIRT776952	hsa-miR-3661	CLIP-seq
MIRT776953	hsa-miR-3922-3p	CLIP-seq
MIRT776954	hsa-miR-3944-5p	CLIP-seq
MIRT776955	hsa-miR-4257	CLIP-seq
MIRT776956	hsa-miR-4284	CLIP-seq
MIRT776957	hsa-miR-631	CLIP-seq
MIRT776958	hsa-miR-661	CLIP-seq
MIRT776959	hsa-miR-1207-3p	CLIP-seq
MIRT776960	hsa-miR-1298	CLIP-seq
MIRT776961	hsa-miR-1912	CLIP-seq
MIRT776962	hsa-miR-3130-5p	CLIP-seq
MIRT776963	hsa-miR-3154	CLIP-seq
MIRT776964	hsa-miR-3185	CLIP-seq
MIRT776965	hsa-miR-338-3p	CLIP-seq
MIRT776966	hsa-miR-3617	CLIP-seq
MIRT776967	hsa-miR-3910	CLIP-seq
MIRT776968	hsa-miR-4310	CLIP-seq
MIRT776969	hsa-miR-4426	CLIP-seq
MIRT776970	hsa-miR-4480	CLIP-seq
MIRT776971	hsa-miR-4482	CLIP-seq
MIRT776972	hsa-miR-4504	CLIP-seq
MIRT776973	hsa-miR-4530	CLIP-seq
MIRT776974	hsa-miR-4647	CLIP-seq
MIRT776975	hsa-miR-4662b	CLIP-seq
MIRT776976	hsa-miR-4708-3p	CLIP-seq
MIRT776977	hsa-miR-4738-3p	CLIP-seq
MIRT776978	hsa-miR-542-3p	CLIP-seq
MIRT776979	hsa-miR-548g	CLIP-seq
MIRT776980	hsa-miR-641	CLIP-seq
MIRT776981	hsa-miR-7	CLIP-seq
MIRT776982	hsa-miR-758	CLIP-seq
MIRT2443545	hsa-miR-3126-5p	CLIP-seq
MIRT2443546	hsa-miR-3919	CLIP-seq
MIRT2443547	hsa-miR-4797-5p	CLIP-seq
MIRT2472904	hsa-miR-3156-5p	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
GATA3	Unknown	9819382
TAL1	Activation	9819382

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001568	Process	Blood vessel development	IEA
GO:0001758	Function	Retinal dehydrogenase activity	IDA	29240402
GO:0001758	Function	Retinal dehydrogenase activity	ISS
GO:0001822	Process	Kidney development	IEA
GO:0001889	Process	Liver development	IEA
GO:0001936	Process	Regulation of endothelial cell proliferation	IEA
GO:0002138	Process	Retinoic acid biosynthetic process	IDA	29240402
GO:0003007	Process	Heart morphogenesis	IEA
GO:0004028	Function	3-chloroallyl aldehyde dehydrogenase activity	ISS
GO:0004029	Function	Aldehyde dehydrogenase (NAD+) activity	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	18495959
GO:0005829	Component	Cytosol	TAS
GO:0006776	Process	Vitamin A metabolic process	NAS	8663198
GO:0007494	Process	Midgut development	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	16166285
GO:0009855	Process	Determination of bilateral symmetry	IEA
GO:0009954	Process	Proximal/distal pattern formation	IEA
GO:0010628	Process	Positive regulation of gene expression	IEA
GO:0014032	Process	Neural crest cell development	IEA
GO:0016331	Process	Morphogenesis of embryonic epithelium	IEA
GO:0016918	Function	Retinal binding	ISS
GO:0021915	Process	Neural tube development	IMP	16237707
GO:0021983	Process	Pituitary gland development	IEA
GO:0030182	Process	Neuron differentiation	IEA
GO:0030324	Process	Lung development	IEA
GO:0030902	Process	Hindbrain development	IEA
GO:0031016	Process	Pancreas development	IEA
GO:0031076	Process	Embryonic camera-type eye development	IEA
GO:0032355	Process	Response to estradiol	IEA
GO:0033189	Process	Response to vitamin A	IEA
GO:0034097	Process	Response to cytokine	IDA	18495959
GO:0035115	Process	Embryonic forelimb morphogenesis	IEA
GO:0035799	Process	Ureter maturation	IEA
GO:0042572	Process	Retinol metabolic process	IEA
GO:0042573	Process	Retinoic acid metabolic process	ISS
GO:0042574	Process	Retinal metabolic process	IEA
GO:0042904	Process	9-cis-retinoic acid biosynthetic process	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048566	Process	Embryonic digestive tract development	IEA
GO:0048738	Process	Cardiac muscle tissue development	IEA
GO:0051289	Process	Protein homotetramerization	IDA	29240402
GO:0060324	Process	Face development	IEA
GO:0071300	Process	Cellular response to retinoic acid	IEA
GO:0090242	Process	Retinoic acid receptor signaling pathway involved in somitogenesis	IEA

Other IDs

• MIM: 603687
• HGNC: 15472
• e!Ensembl: ENSG00000128918

Protein

• UniProt ID: O94788
• Protein name: Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (ALDH1A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II))
• Protein function: Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively (PubMed:2
• PDB: 4X2Q, 6ALJ, 6B5G, 6B5H, 6B5I
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00171	Aldedh	46 → 509	Aldehyde dehydrogenase family	Family

• Sequence:

  MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNP
  ATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVL
  ATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVC
  GQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILP
  GYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD
  LDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQG
  PQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG
  PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ
  SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS

• Sequence length: 518

Pathways

KEGG:

Retinol metabolism
Metabolic pathways

Reactome:

RA biosynthesis pathway

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Alzheimer disease	Alzheimer`s Disease	rs63750215, rs28936379, rs63749851, rs63749884, rs28936380, rs63750048, rs63750579, rs63750264, rs63749964, rs63750671, rs281865161, rs63750066, rs63750399, rs63750734, rs63751039, rs63750973, rs63749810, rs63750643, rs193922916, rs63750306, rs63750590, rs63750526, rs63751235, rs661, rs63751037, rs63749885, rs63750231, rs63751229, rs63751272, rs63751223, rs63750391, rs63751163, rs281875357, rs63751141, rs63750082, rs121917807, rs63751399, rs63750265, rs63751144, rs63750886, rs63751068, rs121917808, rs63749891, rs63750083, rs63749824, rs63750577, rs267606983, rs63750218, rs63751287, rs63750900, rs145518263, rs63751475, rs63750450, rs63749805, rs63751278, rs63751106, rs63750004, rs63749806, rs63751024, rs63750248, rs63750779, rs63751139, rs63750219, rs63750298, rs63750687, rs63750851, rs1553268799, rs1561901881, rs1561905293, rs866101707, rs1566638673, rs63750009, rs1566656702, rs1566657804, rs1567885728, rs1568339995, rs1566630791, rs1555358260, rs63750964, rs1594998354, rs63751316	30805717
Arthritis	Degenerative polyarthritis	rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470	24728293
Atrial fibrillation	Atrial Fibrillation	rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557, rs587777558, rs587777559, rs587777560, rs886037778, rs769405762, rs770372675	27790247
Diabetes	Diabetes	rs80356611	27790247
Diabetes mellitus	Diabetes Mellitus, Diabetes Mellitus, Non-Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs4402960, rs1362648752, rs3745368, rs3792267, rs3842570, rs5030952, rs2975760, rs119489103, rs7903146, rs12255372, rs11196205, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs137852740, rs137852786, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs80356663, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356666, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs387906779, rs141804752, rs182349376, rs184917682, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs61736969, rs587783673, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs797045623, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs1553638903, rs1553638909, rs948820149, rs371977235, rs1553784995, rs76474829, rs200998587, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs776793516, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261	27790247
Age-related macular degeneration	Age related macular degeneration	rs2133900556, rs199474657, rs2274700, rs1410996, rs61750120, rs1800728, rs62654397, rs61749423, rs61751412, rs61749439, rs61751398, rs61752417, rs62645946, rs1801269, rs62646860, rs61750142, rs61750145, rs61750152, rs61751377, rs61753029, rs61751407, rs61751389, rs61750645, rs61750648, rs879255520, rs752147871, rs886044750, rs886044749, rs746541266, rs756840095, rs886044725, rs749526785, rs1057518955, rs1057518767, rs371489809, rs1064793014, rs1571264574, rs1659524475	21665990, 20385819, 20385826, 23455636, 26691988
Metabolic syndrome	Metabolic Syndrome X	rs367643250, rs587777380, rs777736953	29632305, 21386085, 22399527, 30382898
Parkinson disease	Parkinsonian Disorders, Autosomal Dominant Juvenile Parkinson Disease, PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE	rs116074753, rs118203903, rs118203904, rs115735611, rs33939927, rs35801418, rs34805604, rs35870237, rs34995376, rs74315355, rs28940284, rs74315356, rs74315357, rs28940285, rs730880302, rs750664040, rs74315359, rs74315360, rs45539432, rs74315361, rs119451946, rs80356771, rs74500255, rs75822236, rs1141814, rs78973108, rs121908681, rs121908686, rs121908687, rs137853054, rs137853055, rs137853056, rs137853057, rs137853058, rs137853059, rs34424986, rs137853060, rs397518439, rs28938172, rs74315351, rs74315353, rs137853051, rs118192098, rs121917767, rs121918104, rs1589451049, rs104893877, rs104893878, rs283413, rs112176450, rs111290936, rs188286943, rs387906863, rs387906864, rs774631197, rs199935023, rs387906942, rs397514694, rs398122403, rs398122404, rs398122405, rs104886460, rs409652, rs431905511, rs63751392, rs756677845, rs864309527, rs864309650, rs750014782, rs1554391082, rs864622011, rs869312810, rs869312809, rs869312811, rs369100678, rs879253853, rs869320761, rs747506979, rs879255630, rs886039854, rs191486604, rs781442277, rs1060499619, rs751037529, rs55777503, rs768091663, rs34208370, rs1553122929, rs772786691, rs754809877, rs1555907463, rs1557561340, rs781600849, rs141263564, rs1557901552, rs777160388, rs756783990, rs867929413, rs1237637353, rs1005937012, rs755000580, rs747427602, rs1578089802, rs771586218, rs748142049, rs1582953433, rs746646126, rs771529549, rs121918106	25045800
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	16166285
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	26198764, 19703508

Unknown
Disease name	Disease term	dbSNP ID	References
Barrett esophagus	Barrett Esophagus	rs41341748	24121790, 27527254
Cardiovascular diseases	Cardiovascular Diseases		18179892
Coronary heart disease	Coronary heart disease	rs9289231, rs281864746	21347282, 27790247
Digestive system disorders	Digestive System Disorders		24121790
Esophageal cancer	Adenocarcinoma Of Esophagus		24121790, 27527254
Exudative macular degeneration	Exudative age-related macular degeneration, exudative macular degeneration		26691988
Gastrointestinal diseases	Gastrointestinal Diseases		24121790
Geographic atrophy	Geographic Atrophy		26691988
Gout	Gout		22179738
Gouty arthritis	Arthritis, Gouty		22179738
Heart failure	Heart failure	rs121918074, rs142027794, rs148791216, rs72648927, rs71578935, rs142416150, rs199830512, rs755445214, rs150102469, rs779568205, rs907992794, rs1202130741	27790247
Intestinal diseases	Intestinal Diseases		24121790
Ischemic stroke	Ischemic stroke	rs6025, rs1799963, rs1799983	26089329
Malignant neoplasm	Malignant Neoplasms		27790247
Meningomyelocele	Meningomyelocele		16237707
Myelocele	Myelocele		16237707
Osteoarthrosis deformans	Osteoarthrosis Deformans		24728293
Parkinsonian disease	Autosomal Dominant Parkinsonism, Autosomal Recessive Parkinsonism, Familial Juvenile Parkinsonism, Parkinsonism, Juvenile		25045800
Prostatic neoplasms	Prostatic Neoplasms		16166285
Ramsay hunt paralysis syndrome	Ramsay Hunt Paralysis Syndrome		25045800
Stroke	Cerebrovascular accident		27790247, 26089329