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CREG1 (cellular repressor of E1A stimulated genes 1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8804
Gene nameGene Name - the full gene name approved by the HGNC.
Cellular repressor of E1A stimulated genes 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CREG1
SynonymsGene synonyms aliases
CREG
ChromosomeChromosome number
1
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q24.2
SummarySummary of gene provided in NCBI Entrez Gene.
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT007367 hsa-miR-31-5p Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blot 23518389
MIRT028971 hsa-miR-26b-5p Microarray 19088304
MIRT036577 hsa-miR-941 CLASH 23622248
MIRT727936 hsa-miR-15a-5p HITS-CLIP 22473208
MIRT727937 hsa-miR-15b-5p HITS-CLIP 22473208
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003714 Function Transcription corepressor activity TAS 9710587
GO:0005576 Component Extracellular region TAS
GO:0005615 Component Extracellular space IBA 21873635
GO:0005615 Component Extracellular space IDA 25645918
GO:0006357 Process Regulation of transcription by RNA polymerase II TAS 9710587
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID O75629
Protein name Protein CREG1 (Cellular repressor of E1A-stimulated genes 1)
Protein function May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires inte
PDB 1XHN
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13883 Pyrid_oxidase_2
50 216
Domain
Sequence
Sequence length 220
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Neutrophil degranulation
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17013881
Unknown
Disease name Disease term dbSNP ID References
Heart failure Heart Failure, Diastolic rs121918074, rs142027794, rs148791216, rs72648927, rs71578935, rs142416150, rs199830512, rs755445214, rs150102469, rs779568205, rs907992794, rs1202130741 29556499
Prostatic neoplasms Prostatic Neoplasms 17013881

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