Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
8773 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Synaptosome associated protein 23 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
SNAP23 |
SynonymsGene synonyms aliases
|
HsT17016, SNAP-23, SNAP23A, SNAP23B |
ChromosomeChromosome number
|
15 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
15q15.1-q15.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
|
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-a |
miRNAmiRNA information provided by mirtarbase database.
|
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
GO ID |
Ontology |
Definition |
Evidence |
Reference |
GO:0002479 |
Process |
Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent |
TAS |
|
GO:0002553 |
Process |
Histamine secretion by mast cell |
IMP |
18253931 |
GO:0005484 |
Function |
SNAP receptor activity |
IBA |
21873635 |
GO:0005515 |
Function |
Protein binding |
IPI |
12773094, 16189514, 21900206, 24373201, 24705354, 25416956, 26359495, 29549094, 30833792, 32296183 |
GO:0005654 |
Component |
Nucleoplasm |
IDA |
|
GO:0005737 |
Component |
Cytoplasm |
IDA |
18457912 |
GO:0005739 |
Component |
Mitochondrion |
IDA |
26733245 |
GO:0005886 |
Component |
Plasma membrane |
IBA |
21873635 |
GO:0005886 |
Component |
Plasma membrane |
IDA |
18253931, 18457912, 26733245 |
GO:0005886 |
Component |
Plasma membrane |
TAS |
|
GO:0005912 |
Component |
Adherens junction |
IDA |
25468996 |
GO:0005925 |
Component |
Focal adhesion |
HDA |
21423176 |
GO:0006887 |
Process |
Exocytosis |
IBA |
21873635 |
GO:0006892 |
Process |
Post-Golgi vesicle-mediated transport |
TAS |
|
GO:0006903 |
Process |
Vesicle targeting |
TAS |
8663154 |
GO:0006906 |
Process |
Vesicle fusion |
IBA |
21873635 |
GO:0015031 |
Process |
Protein transport |
IEA |
|
GO:0016082 |
Process |
Synaptic vesicle priming |
IBA |
21873635 |
GO:0019905 |
Function |
Syntaxin binding |
IBA |
21873635 |
GO:0019905 |
Function |
Syntaxin binding |
IPI |
16677249 |
GO:0030670 |
Component |
Phagocytic vesicle membrane |
TAS |
|
GO:0031201 |
Component |
SNARE complex |
IBA |
21873635 |
GO:0031201 |
Component |
SNARE complex |
IDA |
18253931 |
GO:0031629 |
Process |
Synaptic vesicle fusion to presynaptic active zone membrane |
IBA |
21873635 |
GO:0035579 |
Component |
Specific granule membrane |
TAS |
|
GO:0042581 |
Component |
Specific granule |
IDA |
18588921 |
GO:0042582 |
Component |
Azurophil granule |
IDA |
18588921 |
GO:0043005 |
Component |
Neuron projection |
IEA |
|
GO:0043312 |
Process |
Neutrophil degranulation |
TAS |
|
GO:0061025 |
Process |
Membrane fusion |
TAS |
10839363 |
GO:0070062 |
Component |
Extracellular exosome |
HDA |
19056867, 20458337 |
GO:0070821 |
Component |
Tertiary granule membrane |
TAS |
|
GO:0098793 |
Component |
Presynapse |
IEA |
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
O00161 |
Protein name |
Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23) |
Protein function |
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. |
PDB |
1NHL
,
3ZUS
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00835 |
SNAP-25 |
86 → 147 |
SNAP-25 family |
Family |
|
Sequence |
|
Sequence length |
211 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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|
Associated diseases
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Myocardial ischemia |
Myocardial Ischemia |
|
16214533 |
|