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SNAP23 (synaptosome associated protein 23)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8773
Gene nameGene Name - the full gene name approved by the HGNC.
Synaptosome associated protein 23
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SNAP23
SynonymsGene synonyms aliases
HsT17016, SNAP-23, SNAP23A, SNAP23B
ChromosomeChromosome number
15
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q15.1-q15.2
SummarySummary of gene provided in NCBI Entrez Gene.
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-a
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001590 hsa-let-7b-5p pSILAC 18668040
MIRT023206 hsa-miR-124-3p Proteomics;Microarray 18668037
MIRT025561 hsa-miR-34a-5p Proteomics 21566225
MIRT027856 hsa-miR-98-5p Microarray 19088304
MIRT001590 hsa-let-7b-5p Proteomics;Other 18668040
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0002479 Process Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS
GO:0002553 Process Histamine secretion by mast cell IMP 18253931
GO:0005484 Function SNAP receptor activity IBA 21873635
GO:0005515 Function Protein binding IPI 12773094, 16189514, 21900206, 24373201, 24705354, 25416956, 26359495, 29549094, 30833792, 32296183
GO:0005654 Component Nucleoplasm IDA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID O00161
Protein name Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23)
Protein function Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
PDB 1NHL , 3ZUS
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00835 SNAP-25
86 147
SNAP-25 family
Family
Sequence
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLD
QINKDMRETEKTLTELNKCCGLCVCPCNRTKNFESGKAYKTTWGDGGENSPCNVVSKQPG
PVTNGQLQQPTTGAASGGYIKRITNDA
REDEMEENLTQVGSILGNLKDMALNIGNEIDAQ
NPQIKRITDKADTNRDRIDIANARAKKLIDS
Sequence length 211
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
Reactome
  SNARE interactions in vesicular transport
Platelet activation
  ER-Phagosome pathway
trans-Golgi Network Vesicle Budding
Neutrophil degranulation
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Myocardial ischemia Myocardial Ischemia 16214533

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