SERPINH1 (serpin family H member 1)

Gene

• Entrez ID: 871
• Gene name: Serpin family H member 1
• Gene symbol: SERPINH1
• Synonyms: AsTP3, CBP1, CBP2, HSP47, OI10, PIG14, PPROM, RA-A47, SERPINH2, gp46
• Chromosome: 11
• Chromosome location: 11q13.5
• Summary: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs137853892	T>C	Pathogenic	Coding sequence variant, missense variant
rs886039819	T>C	Pathogenic	Missense variant, coding sequence variant
rs1565244847	->T	Pathogenic	Coding sequence variant, stop gained

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022927	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT029883	hsa-miR-26b-5p	Microarray	19088304
MIRT041847	hsa-miR-484	CLASH	23622248
MIRT041847	hsa-miR-484	CLASH	23622248
MIRT053747	hsa-miR-29b-3p	Microarray	22942087
MIRT437548	hsa-miR-29a-3p	Luciferase reporter assay	22745231
MIRT053747	hsa-miR-29b-3p	Luciferase reporter assay	22745231
MIRT437560	hsa-miR-29c-3p	Luciferase reporter assay	22745231
MIRT437570	hsa-miR-767-5p	Luciferase reporter assay	22745231
MIRT437548	hsa-miR-29a-3p	Luciferase reporter assay, qRT-PCR, Western blot	24141696
MIRT437548	hsa-miR-29a-3p	Luciferase reporter assay, qRT-PCR, Western blot	24141696
MIRT437548	hsa-miR-29a-3p	Luciferase reporter assay, qRT-PCR, Western blot	24141696
MIRT437548	hsa-miR-29a-3p	Luciferase reporter assay, qRT-PCR, Western blot	24141696
MIRT231349	hsa-miR-5197-3p	HITS-CLIP	23313552
MIRT699728	hsa-miR-6854-5p	HITS-CLIP	23313552
MIRT394812	hsa-miR-4446-3p	HITS-CLIP	23313552
MIRT334257	hsa-miR-5002-5p	HITS-CLIP	23313552
MIRT334256	hsa-miR-4750-3p	HITS-CLIP	23313552
MIRT334255	hsa-miR-3064-5p	HITS-CLIP	23313552
MIRT334258	hsa-miR-6504-5p	HITS-CLIP	23313552
MIRT334259	hsa-miR-6859-3p	HITS-CLIP	23313552
MIRT699727	hsa-miR-6846-3p	HITS-CLIP	23313552
MIRT394815	hsa-miR-4721	HITS-CLIP	23313552
MIRT334260	hsa-miR-7158-5p	HITS-CLIP	23313552
MIRT394817	hsa-miR-5580-5p	HITS-CLIP	23313552
MIRT394813	hsa-miR-4492	HITS-CLIP	23313552
MIRT394814	hsa-miR-4498	HITS-CLIP	23313552
MIRT394816	hsa-miR-5001-5p	HITS-CLIP	23313552
MIRT394810	hsa-miR-762	HITS-CLIP	23313552
MIRT699726	hsa-miR-142-3p	HITS-CLIP	23313552
MIRT231348	hsa-miR-3591-5p	HITS-CLIP	23313552
MIRT699725	hsa-miR-133a-3p	HITS-CLIP	23313552
MIRT699724	hsa-miR-133b	HITS-CLIP	23313552
MIRT639940	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT639939	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT639938	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT639937	hsa-miR-5193	HITS-CLIP	23824327
MIRT639936	hsa-miR-1283	HITS-CLIP	23824327
MIRT639935	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT639934	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT639933	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT639932	hsa-miR-187-5p	HITS-CLIP	23824327
MIRT639931	hsa-miR-548v	HITS-CLIP	23824327
MIRT639930	hsa-miR-221-3p	HITS-CLIP	23824327
MIRT639929	hsa-miR-222-3p	HITS-CLIP	23824327
MIRT639928	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639927	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT639926	hsa-miR-1262	HITS-CLIP	23824327
MIRT639925	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT639924	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT639923	hsa-miR-6741-5p	HITS-CLIP	23824327
MIRT539659	hsa-miR-892b	PAR-CLIP	21572407
MIRT539658	hsa-miR-4463	PAR-CLIP	21572407
MIRT539657	hsa-miR-1825	PAR-CLIP	21572407
MIRT539656	hsa-miR-199a-5p	PAR-CLIP	21572407
MIRT539655	hsa-miR-199b-5p	PAR-CLIP	21572407
MIRT539654	hsa-miR-149-5p	PAR-CLIP	21572407
MIRT468538	hsa-miR-370-5p	PAR-CLIP	22012620
MIRT534383	hsa-miR-4726-3p	PAR-CLIP	22012620
MIRT468537	hsa-miR-361-3p	PAR-CLIP	22012620
MIRT468535	hsa-miR-3140-5p	PAR-CLIP	22012620
MIRT468534	hsa-miR-3667-3p	PAR-CLIP	22012620
MIRT468532	hsa-miR-378a-5p	PAR-CLIP	22012620
MIRT468531	hsa-miR-1200	PAR-CLIP	22012620
MIRT498688	hsa-miR-200b-3p	PAR-CLIP	24398324
MIRT498687	hsa-miR-200c-3p	PAR-CLIP	24398324
MIRT498686	hsa-miR-429	PAR-CLIP	24398324
MIRT334252	hsa-miR-4517	PAR-CLIP	24398324
MIRT498685	hsa-miR-6808-5p	PAR-CLIP	24398324
MIRT498683	hsa-miR-6893-5p	PAR-CLIP	24398324
MIRT498684	hsa-miR-940	PAR-CLIP	24398324
MIRT334253	hsa-miR-4794	PAR-CLIP	24398324
MIRT334250	hsa-miR-664a-5p	PAR-CLIP	24398324
MIRT373698	hsa-miR-1827	PAR-CLIP	24398324
MIRT498682	hsa-miR-6765-5p	PAR-CLIP	24398324
MIRT498681	hsa-miR-1304-5p	PAR-CLIP	24398324
MIRT468538	hsa-miR-370-5p	PAR-CLIP	23592263
MIRT468537	hsa-miR-361-3p	PAR-CLIP	23592263
MIRT468536	hsa-miR-5088-3p	PAR-CLIP	23592263
MIRT468535	hsa-miR-3140-5p	PAR-CLIP	23592263
MIRT468534	hsa-miR-3667-3p	PAR-CLIP	23592263
MIRT468533	hsa-miR-9-5p	PAR-CLIP	23592263
MIRT468532	hsa-miR-378a-5p	PAR-CLIP	23592263
MIRT468531	hsa-miR-1200	PAR-CLIP	23592263
MIRT468530	hsa-miR-7150	PAR-CLIP	23592263
MIRT468529	hsa-miR-182-5p	PAR-CLIP	23592263
MIRT468528	hsa-miR-1271-5p	PAR-CLIP	23592263
MIRT468527	hsa-miR-96-5p	PAR-CLIP	23592263
MIRT437548	hsa-miR-29a-3p	Next Generation Sequencing (NGS), qRT-PCR, Western blot	26199111
MIRT053747	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	25744716
MIRT053747	hsa-miR-29b-3p	Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blot	27477081
MIRT053747	hsa-miR-29b-3p	Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blot	27477081
MIRT468531	hsa-miR-1200	PAR-CLIP	26701625
MIRT699726	hsa-miR-142-3p	PAR-CLIP	26701625
MIRT699726	hsa-miR-142-3p	PAR-CLIP	26701625
MIRT468535	hsa-miR-3140-5p	PAR-CLIP	26701625
MIRT231348	hsa-miR-3591-5p	PAR-CLIP	26701625
MIRT231348	hsa-miR-3591-5p	PAR-CLIP	26701625
MIRT468537	hsa-miR-361-3p	PAR-CLIP	26701625
MIRT468538	hsa-miR-370-5p	PAR-CLIP	26701625
MIRT468532	hsa-miR-378a-5p	PAR-CLIP	26701625
MIRT394812	hsa-miR-4446-3p	PAR-CLIP	26701625
MIRT394812	hsa-miR-4446-3p	PAR-CLIP	26701625
MIRT394813	hsa-miR-4492	PAR-CLIP	26701625
MIRT394813	hsa-miR-4492	PAR-CLIP	26701625
MIRT394814	hsa-miR-4498	PAR-CLIP	26701625
MIRT394814	hsa-miR-4498	PAR-CLIP	26701625
MIRT394815	hsa-miR-4721	PAR-CLIP	26701625
MIRT394815	hsa-miR-4721	PAR-CLIP	26701625
MIRT534383	hsa-miR-4726-3p	PAR-CLIP	26701625
MIRT394816	hsa-miR-5001-5p	PAR-CLIP	26701625
MIRT394816	hsa-miR-5001-5p	PAR-CLIP	26701625
MIRT231349	hsa-miR-5197-3p	PAR-CLIP	26701625
MIRT231349	hsa-miR-5197-3p	PAR-CLIP	26701625
MIRT394817	hsa-miR-5580-5p	PAR-CLIP	26701625
MIRT394817	hsa-miR-5580-5p	PAR-CLIP	26701625
MIRT394810	hsa-miR-762	PAR-CLIP	26701625
MIRT394810	hsa-miR-762	PAR-CLIP	26701625
MIRT539654	hsa-miR-149-5p	PAR-CLIP	27292025
MIRT539657	hsa-miR-1825	PAR-CLIP	27292025
MIRT539656	hsa-miR-199a-5p	PAR-CLIP	27292025
MIRT539655	hsa-miR-199b-5p	PAR-CLIP	27292025
MIRT539658	hsa-miR-4463	PAR-CLIP	27292025
MIRT539659	hsa-miR-892b	PAR-CLIP	27292025
MIRT735457	hsa-miR-148a-5p	Luciferase reporter assay, Western blotting, Immunohistochemistry (IHC), qRT-PCR	32235846
MIRT231349	hsa-miR-5197-3p	HITS-CLIP	23313552
MIRT699728	hsa-miR-6854-5p	HITS-CLIP	23313552
MIRT394812	hsa-miR-4446-3p	HITS-CLIP	23313552
MIRT334257	hsa-miR-5002-5p	HITS-CLIP	23313552
MIRT334256	hsa-miR-4750-3p	HITS-CLIP	23313552
MIRT334255	hsa-miR-3064-5p	HITS-CLIP	23313552
MIRT334258	hsa-miR-6504-5p	HITS-CLIP	23313552
MIRT334259	hsa-miR-6859-3p	HITS-CLIP	23313552
MIRT699727	hsa-miR-6846-3p	HITS-CLIP	23313552
MIRT394815	hsa-miR-4721	HITS-CLIP	23313552
MIRT334260	hsa-miR-7158-5p	HITS-CLIP	23313552
MIRT394817	hsa-miR-5580-5p	HITS-CLIP	23313552
MIRT394813	hsa-miR-4492	HITS-CLIP	23313552
MIRT394814	hsa-miR-4498	HITS-CLIP	23313552
MIRT394816	hsa-miR-5001-5p	HITS-CLIP	23313552
MIRT394810	hsa-miR-762	HITS-CLIP	23313552
MIRT699726	hsa-miR-142-3p	HITS-CLIP	23313552
MIRT231348	hsa-miR-3591-5p	HITS-CLIP	23313552
MIRT699725	hsa-miR-133a-3p	HITS-CLIP	23313552
MIRT699724	hsa-miR-133b	HITS-CLIP	23313552
MIRT639940	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT639939	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT639938	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT639937	hsa-miR-5193	HITS-CLIP	23824327
MIRT639936	hsa-miR-1283	HITS-CLIP	23824327
MIRT639935	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT639934	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT639933	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT639932	hsa-miR-187-5p	HITS-CLIP	23824327
MIRT639931	hsa-miR-548v	HITS-CLIP	23824327
MIRT639930	hsa-miR-221-3p	HITS-CLIP	23824327
MIRT639929	hsa-miR-222-3p	HITS-CLIP	23824327
MIRT639928	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639927	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT639926	hsa-miR-1262	HITS-CLIP	23824327
MIRT639925	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT639924	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT639923	hsa-miR-6741-5p	HITS-CLIP	23824327
MIRT539659	hsa-miR-892b	PAR-CLIP	21572407
MIRT539658	hsa-miR-4463	PAR-CLIP	21572407
MIRT539657	hsa-miR-1825	PAR-CLIP	21572407
MIRT539656	hsa-miR-199a-5p	PAR-CLIP	21572407
MIRT539655	hsa-miR-199b-5p	PAR-CLIP	21572407
MIRT539654	hsa-miR-149-5p	PAR-CLIP	21572407
MIRT468538	hsa-miR-370-5p	PAR-CLIP	22012620
MIRT534383	hsa-miR-4726-3p	PAR-CLIP	22012620
MIRT468537	hsa-miR-361-3p	PAR-CLIP	22012620
MIRT468535	hsa-miR-3140-5p	PAR-CLIP	22012620
MIRT468534	hsa-miR-3667-3p	PAR-CLIP	22012620
MIRT468532	hsa-miR-378a-5p	PAR-CLIP	22012620
MIRT468531	hsa-miR-1200	PAR-CLIP	22012620
MIRT498688	hsa-miR-200b-3p	PAR-CLIP	24398324
MIRT498687	hsa-miR-200c-3p	PAR-CLIP	24398324
MIRT498686	hsa-miR-429	PAR-CLIP	24398324
MIRT334252	hsa-miR-4517	PAR-CLIP	24398324
MIRT498685	hsa-miR-6808-5p	PAR-CLIP	24398324
MIRT498683	hsa-miR-6893-5p	PAR-CLIP	24398324
MIRT498684	hsa-miR-940	PAR-CLIP	24398324
MIRT334253	hsa-miR-4794	PAR-CLIP	24398324
MIRT334250	hsa-miR-664a-5p	PAR-CLIP	24398324
MIRT373698	hsa-miR-1827	PAR-CLIP	24398324
MIRT498682	hsa-miR-6765-5p	PAR-CLIP	24398324
MIRT498681	hsa-miR-1304-5p	PAR-CLIP	24398324
MIRT468538	hsa-miR-370-5p	PAR-CLIP	23592263
MIRT468537	hsa-miR-361-3p	PAR-CLIP	23592263
MIRT468536	hsa-miR-5088-3p	PAR-CLIP	23592263
MIRT468535	hsa-miR-3140-5p	PAR-CLIP	23592263
MIRT468534	hsa-miR-3667-3p	PAR-CLIP	23592263
MIRT468533	hsa-miR-9-5p	PAR-CLIP	23592263
MIRT468532	hsa-miR-378a-5p	PAR-CLIP	23592263
MIRT468531	hsa-miR-1200	PAR-CLIP	23592263
MIRT468530	hsa-miR-7150	PAR-CLIP	23592263
MIRT468529	hsa-miR-182-5p	PAR-CLIP	23592263
MIRT468528	hsa-miR-1271-5p	PAR-CLIP	23592263
MIRT468527	hsa-miR-96-5p	PAR-CLIP	23592263
MIRT1338917	hsa-miR-122	CLIP-seq
MIRT1338918	hsa-miR-3065-5p	CLIP-seq
MIRT1338919	hsa-miR-3127-5p	CLIP-seq
MIRT1338920	hsa-miR-3192	CLIP-seq
MIRT1338921	hsa-miR-3199	CLIP-seq
MIRT1338922	hsa-miR-3679-3p	CLIP-seq
MIRT1338923	hsa-miR-3691-3p	CLIP-seq
MIRT1338924	hsa-miR-3918	CLIP-seq
MIRT1338925	hsa-miR-4314	CLIP-seq
MIRT1338926	hsa-miR-432	CLIP-seq
MIRT1338927	hsa-miR-4436b-3p	CLIP-seq
MIRT1338928	hsa-miR-4452	CLIP-seq
MIRT1338929	hsa-miR-4514	CLIP-seq
MIRT1338930	hsa-miR-4641	CLIP-seq
MIRT1338931	hsa-miR-4646-5p	CLIP-seq
MIRT1338932	hsa-miR-4692	CLIP-seq
MIRT1338933	hsa-miR-4747-5p	CLIP-seq
MIRT1338934	hsa-miR-493	CLIP-seq
MIRT1338935	hsa-miR-103a	CLIP-seq
MIRT1338936	hsa-miR-107	CLIP-seq
MIRT1338937	hsa-miR-1180	CLIP-seq
MIRT1338938	hsa-miR-1184	CLIP-seq
MIRT1338917	hsa-miR-122	CLIP-seq
MIRT1338939	hsa-miR-1253	CLIP-seq
MIRT1338940	hsa-miR-1254	CLIP-seq
MIRT1338941	hsa-miR-125a-3p	CLIP-seq
MIRT1338942	hsa-miR-1265	CLIP-seq
MIRT1338943	hsa-miR-1304	CLIP-seq
MIRT1338944	hsa-miR-188-3p	CLIP-seq
MIRT1338945	hsa-miR-1915	CLIP-seq
MIRT1338946	hsa-miR-200b	CLIP-seq
MIRT1338947	hsa-miR-200c	CLIP-seq
MIRT1338948	hsa-miR-24	CLIP-seq
MIRT1338949	hsa-miR-2681	CLIP-seq
MIRT1338950	hsa-miR-29a	CLIP-seq
MIRT1338951	hsa-miR-29b	CLIP-seq
MIRT1338952	hsa-miR-29c	CLIP-seq
MIRT1338953	hsa-miR-3065-3p	CLIP-seq
MIRT1338918	hsa-miR-3065-5p	CLIP-seq
MIRT1338954	hsa-miR-3116	CLIP-seq
MIRT1338955	hsa-miR-3126-3p	CLIP-seq
MIRT1338919	hsa-miR-3127-5p	CLIP-seq
MIRT1338956	hsa-miR-3136-3p	CLIP-seq
MIRT1338957	hsa-miR-3150a-3p	CLIP-seq
MIRT1338958	hsa-miR-3175	CLIP-seq
MIRT1338920	hsa-miR-3192	CLIP-seq
MIRT1338921	hsa-miR-3199	CLIP-seq
MIRT1338959	hsa-miR-342-5p	CLIP-seq
MIRT1338960	hsa-miR-3612	CLIP-seq
MIRT1338922	hsa-miR-3679-3p	CLIP-seq
MIRT1338961	hsa-miR-3692	CLIP-seq
MIRT1338924	hsa-miR-3918	CLIP-seq
MIRT1338962	hsa-miR-4269	CLIP-seq
MIRT1338963	hsa-miR-4281	CLIP-seq
MIRT1338964	hsa-miR-4310	CLIP-seq
MIRT1338925	hsa-miR-4314	CLIP-seq
MIRT1338926	hsa-miR-432	CLIP-seq
MIRT1338965	hsa-miR-4425	CLIP-seq
MIRT1338927	hsa-miR-4436b-3p	CLIP-seq
MIRT1338966	hsa-miR-4437	CLIP-seq
MIRT1338928	hsa-miR-4452	CLIP-seq
MIRT1338967	hsa-miR-4487	CLIP-seq
MIRT1338968	hsa-miR-4491	CLIP-seq
MIRT1338969	hsa-miR-4497	CLIP-seq
MIRT1338970	hsa-miR-450b-3p	CLIP-seq
MIRT1338929	hsa-miR-4514	CLIP-seq
MIRT1338931	hsa-miR-4646-5p	CLIP-seq
MIRT1338971	hsa-miR-4653-3p	CLIP-seq
MIRT1338972	hsa-miR-4657	CLIP-seq
MIRT1338973	hsa-miR-4664-3p	CLIP-seq
MIRT1338974	hsa-miR-4664-5p	CLIP-seq
MIRT1338975	hsa-miR-4667-5p	CLIP-seq
MIRT1338976	hsa-miR-4681	CLIP-seq
MIRT1338932	hsa-miR-4692	CLIP-seq
MIRT1338977	hsa-miR-4700-5p	CLIP-seq
MIRT1338978	hsa-miR-4731-5p	CLIP-seq
MIRT1338979	hsa-miR-4742-5p	CLIP-seq
MIRT1338933	hsa-miR-4747-5p	CLIP-seq
MIRT1338980	hsa-miR-4764-5p	CLIP-seq
MIRT1338934	hsa-miR-493	CLIP-seq
MIRT1338981	hsa-miR-550a	CLIP-seq
MIRT1338982	hsa-miR-572	CLIP-seq
MIRT1338983	hsa-miR-602	CLIP-seq
MIRT1338984	hsa-miR-619	CLIP-seq
MIRT1338985	hsa-miR-637	CLIP-seq
MIRT1338986	hsa-miR-650	CLIP-seq
MIRT1338987	hsa-miR-661	CLIP-seq
MIRT1338988	hsa-miR-769-3p	CLIP-seq
MIRT1338989	hsa-miR-939	CLIP-seq
MIRT1338919	hsa-miR-3127-5p	CLIP-seq
MIRT1338920	hsa-miR-3192	CLIP-seq
MIRT1338921	hsa-miR-3199	CLIP-seq
MIRT1338923	hsa-miR-3691-3p	CLIP-seq
MIRT1338924	hsa-miR-3918	CLIP-seq
MIRT1338925	hsa-miR-4314	CLIP-seq
MIRT1338927	hsa-miR-4436b-3p	CLIP-seq
MIRT1338929	hsa-miR-4514	CLIP-seq
MIRT1338931	hsa-miR-4646-5p	CLIP-seq
MIRT1338975	hsa-miR-4667-5p	CLIP-seq
MIRT1338932	hsa-miR-4692	CLIP-seq
MIRT1338977	hsa-miR-4700-5p	CLIP-seq
MIRT2100179	hsa-miR-133a	CLIP-seq
MIRT1338919	hsa-miR-3127-5p	CLIP-seq
MIRT1338920	hsa-miR-3192	CLIP-seq
MIRT1338921	hsa-miR-3199	CLIP-seq
MIRT2100180	hsa-miR-342-3p	CLIP-seq
MIRT1338924	hsa-miR-3918	CLIP-seq
MIRT1338962	hsa-miR-4269	CLIP-seq
MIRT1338925	hsa-miR-4314	CLIP-seq
MIRT1338929	hsa-miR-4514	CLIP-seq
MIRT1338931	hsa-miR-4646-5p	CLIP-seq
MIRT1338976	hsa-miR-4681	CLIP-seq
MIRT1338932	hsa-miR-4692	CLIP-seq
MIRT1338979	hsa-miR-4742-5p	CLIP-seq
MIRT1338933	hsa-miR-4747-5p	CLIP-seq
MIRT1338934	hsa-miR-493	CLIP-seq
MIRT2100181	hsa-miR-513a-5p	CLIP-seq
MIRT2100182	hsa-miR-552	CLIP-seq
MIRT1338982	hsa-miR-572	CLIP-seq
MIRT1338983	hsa-miR-602	CLIP-seq
MIRT2100183	hsa-miR-4667-3p	CLIP-seq
MIRT1338917	hsa-miR-122	CLIP-seq
MIRT1338939	hsa-miR-1253	CLIP-seq
MIRT1338941	hsa-miR-125a-3p	CLIP-seq
MIRT1338943	hsa-miR-1304	CLIP-seq
MIRT1338946	hsa-miR-200b	CLIP-seq
MIRT1338947	hsa-miR-200c	CLIP-seq
MIRT1338955	hsa-miR-3126-3p	CLIP-seq
MIRT1338919	hsa-miR-3127-5p	CLIP-seq
MIRT1338920	hsa-miR-3192	CLIP-seq
MIRT1338921	hsa-miR-3199	CLIP-seq
MIRT1338923	hsa-miR-3691-3p	CLIP-seq
MIRT1338924	hsa-miR-3918	CLIP-seq
MIRT1338962	hsa-miR-4269	CLIP-seq
MIRT1338925	hsa-miR-4314	CLIP-seq
MIRT1338927	hsa-miR-4436b-3p	CLIP-seq
MIRT1338928	hsa-miR-4452	CLIP-seq
MIRT1338929	hsa-miR-4514	CLIP-seq
MIRT1338930	hsa-miR-4641	CLIP-seq
MIRT1338931	hsa-miR-4646-5p	CLIP-seq
MIRT1338971	hsa-miR-4653-3p	CLIP-seq
MIRT1338975	hsa-miR-4667-5p	CLIP-seq
MIRT1338976	hsa-miR-4681	CLIP-seq
MIRT1338932	hsa-miR-4692	CLIP-seq
MIRT1338977	hsa-miR-4700-5p	CLIP-seq
MIRT1338979	hsa-miR-4742-5p	CLIP-seq
MIRT1338933	hsa-miR-4747-5p	CLIP-seq
MIRT1338934	hsa-miR-493	CLIP-seq
MIRT2100181	hsa-miR-513a-5p	CLIP-seq
MIRT2100182	hsa-miR-552	CLIP-seq
MIRT1338982	hsa-miR-572	CLIP-seq
MIRT1338983	hsa-miR-602	CLIP-seq
MIRT1338984	hsa-miR-619	CLIP-seq
MIRT1338985	hsa-miR-637	CLIP-seq
MIRT1338917	hsa-miR-122	CLIP-seq
MIRT1338975	hsa-miR-4667-5p	CLIP-seq
MIRT1338977	hsa-miR-4700-5p	CLIP-seq
MIRT1338935	hsa-miR-103a	CLIP-seq
MIRT1338936	hsa-miR-107	CLIP-seq
MIRT1338937	hsa-miR-1180	CLIP-seq
MIRT1338938	hsa-miR-1184	CLIP-seq
MIRT1338917	hsa-miR-122	CLIP-seq
MIRT2440168	hsa-miR-1237	CLIP-seq
MIRT2440169	hsa-miR-1248	CLIP-seq
MIRT1338939	hsa-miR-1253	CLIP-seq
MIRT1338940	hsa-miR-1254	CLIP-seq
MIRT1338941	hsa-miR-125a-3p	CLIP-seq
MIRT1338942	hsa-miR-1265	CLIP-seq
MIRT1338943	hsa-miR-1304	CLIP-seq
MIRT2100179	hsa-miR-133a	CLIP-seq
MIRT2440170	hsa-miR-1343	CLIP-seq
MIRT1338944	hsa-miR-188-3p	CLIP-seq
MIRT2440171	hsa-miR-1913	CLIP-seq
MIRT1338945	hsa-miR-1915	CLIP-seq
MIRT1338948	hsa-miR-24	CLIP-seq
MIRT1338949	hsa-miR-2681	CLIP-seq
MIRT1338953	hsa-miR-3065-3p	CLIP-seq
MIRT1338954	hsa-miR-3116	CLIP-seq
MIRT1338955	hsa-miR-3126-3p	CLIP-seq
MIRT1338919	hsa-miR-3127-5p	CLIP-seq
MIRT1338956	hsa-miR-3136-3p	CLIP-seq
MIRT1338920	hsa-miR-3192	CLIP-seq
MIRT1338921	hsa-miR-3199	CLIP-seq
MIRT2440172	hsa-miR-324-3p	CLIP-seq
MIRT2100180	hsa-miR-342-3p	CLIP-seq
MIRT1338959	hsa-miR-342-5p	CLIP-seq
MIRT2440173	hsa-miR-346	CLIP-seq
MIRT1338923	hsa-miR-3691-3p	CLIP-seq
MIRT1338961	hsa-miR-3692	CLIP-seq
MIRT1338924	hsa-miR-3918	CLIP-seq
MIRT1338963	hsa-miR-4281	CLIP-seq
MIRT2440174	hsa-miR-4286	CLIP-seq
MIRT2440175	hsa-miR-4300	CLIP-seq
MIRT1338964	hsa-miR-4310	CLIP-seq
MIRT1338925	hsa-miR-4314	CLIP-seq
MIRT1338927	hsa-miR-4436b-3p	CLIP-seq
MIRT1338966	hsa-miR-4437	CLIP-seq
MIRT2440176	hsa-miR-4448	CLIP-seq
MIRT1338928	hsa-miR-4452	CLIP-seq
MIRT1338968	hsa-miR-4491	CLIP-seq
MIRT1338969	hsa-miR-4497	CLIP-seq
MIRT1338929	hsa-miR-4514	CLIP-seq
MIRT1338930	hsa-miR-4641	CLIP-seq
MIRT1338931	hsa-miR-4646-5p	CLIP-seq
MIRT1338971	hsa-miR-4653-3p	CLIP-seq
MIRT1338972	hsa-miR-4657	CLIP-seq
MIRT1338973	hsa-miR-4664-3p	CLIP-seq
MIRT1338974	hsa-miR-4664-5p	CLIP-seq
MIRT2100183	hsa-miR-4667-3p	CLIP-seq
MIRT1338975	hsa-miR-4667-5p	CLIP-seq
MIRT1338932	hsa-miR-4692	CLIP-seq
MIRT1338977	hsa-miR-4700-5p	CLIP-seq
MIRT2440177	hsa-miR-4749-3p	CLIP-seq
MIRT1338980	hsa-miR-4764-5p	CLIP-seq
MIRT2100181	hsa-miR-513a-5p	CLIP-seq
MIRT2440178	hsa-miR-513c	CLIP-seq
MIRT2440179	hsa-miR-514b-5p	CLIP-seq
MIRT2440180	hsa-miR-526b	CLIP-seq
MIRT1338981	hsa-miR-550a	CLIP-seq
MIRT2100182	hsa-miR-552	CLIP-seq
MIRT1338984	hsa-miR-619	CLIP-seq
MIRT1338985	hsa-miR-637	CLIP-seq
MIRT1338987	hsa-miR-661	CLIP-seq
MIRT2440181	hsa-miR-920	CLIP-seq
MIRT1338939	hsa-miR-1253	CLIP-seq
MIRT1338941	hsa-miR-125a-3p	CLIP-seq
MIRT1338943	hsa-miR-1304	CLIP-seq
MIRT2100179	hsa-miR-133a	CLIP-seq
MIRT2620661	hsa-miR-1470	CLIP-seq
MIRT1338946	hsa-miR-200b	CLIP-seq
MIRT1338947	hsa-miR-200c	CLIP-seq
MIRT2620662	hsa-miR-3127-3p	CLIP-seq
MIRT1338919	hsa-miR-3127-5p	CLIP-seq
MIRT1338920	hsa-miR-3192	CLIP-seq
MIRT1338921	hsa-miR-3199	CLIP-seq
MIRT2100180	hsa-miR-342-3p	CLIP-seq
MIRT1338922	hsa-miR-3679-3p	CLIP-seq
MIRT1338924	hsa-miR-3918	CLIP-seq
MIRT1338925	hsa-miR-4314	CLIP-seq
MIRT1338927	hsa-miR-4436b-3p	CLIP-seq
MIRT1338929	hsa-miR-4514	CLIP-seq
MIRT1338931	hsa-miR-4646-5p	CLIP-seq
MIRT2100183	hsa-miR-4667-3p	CLIP-seq
MIRT1338932	hsa-miR-4692	CLIP-seq
MIRT2100181	hsa-miR-513a-5p	CLIP-seq
MIRT2100182	hsa-miR-552	CLIP-seq
MIRT1338984	hsa-miR-619	CLIP-seq
MIRT2620663	hsa-miR-642a	CLIP-seq
MIRT1338939	hsa-miR-1253	CLIP-seq
MIRT1338941	hsa-miR-125a-3p	CLIP-seq
MIRT1338943	hsa-miR-1304	CLIP-seq
MIRT2100179	hsa-miR-133a	CLIP-seq
MIRT2620661	hsa-miR-1470	CLIP-seq
MIRT1338944	hsa-miR-188-3p	CLIP-seq
MIRT1338946	hsa-miR-200b	CLIP-seq
MIRT1338947	hsa-miR-200c	CLIP-seq
MIRT2620662	hsa-miR-3127-3p	CLIP-seq
MIRT1338919	hsa-miR-3127-5p	CLIP-seq
MIRT1338956	hsa-miR-3136-3p	CLIP-seq
MIRT1338920	hsa-miR-3192	CLIP-seq
MIRT1338921	hsa-miR-3199	CLIP-seq
MIRT2100180	hsa-miR-342-3p	CLIP-seq
MIRT1338922	hsa-miR-3679-3p	CLIP-seq
MIRT1338924	hsa-miR-3918	CLIP-seq
MIRT1338925	hsa-miR-4314	CLIP-seq
MIRT1338927	hsa-miR-4436b-3p	CLIP-seq
MIRT1338929	hsa-miR-4514	CLIP-seq
MIRT1338931	hsa-miR-4646-5p	CLIP-seq
MIRT2100183	hsa-miR-4667-3p	CLIP-seq
MIRT1338932	hsa-miR-4692	CLIP-seq
MIRT2100181	hsa-miR-513a-5p	CLIP-seq
MIRT2100182	hsa-miR-552	CLIP-seq
MIRT1338984	hsa-miR-619	CLIP-seq
MIRT2620663	hsa-miR-642a	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003433	Process	Chondrocyte development involved in endochondral bone morphogenesis	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0004867	Function	Serine-type endopeptidase inhibitor activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005518	Function	Collagen binding	NAS	7656593
GO:0005615	Component	Extracellular space	IEA
GO:0005783	Component	Endoplasmic reticulum	IBA	21873635
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	NAS	7656593
GO:0005788	Component	Endoplasmic reticulum lumen	TAS
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IDA	15308636
GO:0006986	Process	Response to unfolded protein	TAS	1309665, 10023073
GO:0010951	Process	Negative regulation of endopeptidase activity	IBA	21873635
GO:0030199	Process	Collagen fibril organization	IBA	21873635
GO:0032964	Process	Collagen biosynthetic process	IEA
GO:0045121	Component	Membrane raft	IDA	25204797
GO:0051082	Function	Unfolded protein binding	IEA
GO:0051604	Process	Protein maturation	IEA
GO:0062023	Component	Collagen-containing extracellular matrix	HDA	25037231, 28675934
GO:0062023	Component	Collagen-containing extracellular matrix	HDA	28327460

Other IDs

• MIM: 600943
• HGNC: 1546
• e!Ensembl: ENSG00000149257

Protein

• UniProt ID: P50454
• Protein name: Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47)
• Protein function: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00079	Serpin	45 → 409	Serpin (serine protease inhibitor)	Domain

• Sequence:

  MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
  DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
  STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
  TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
  GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
  AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
  TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL

• Sequence length: 418

Pathways

Reactome:

Collagen biosynthesis and modifying enzymes

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Coronary artery disease	Coronary Artery Disease	rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs405509, rs1555800701, rs1215189537	29212778, 23202125
Dentinogenesis imperfecta	Dentinogenesis Imperfecta	rs121912985, rs1560477489, rs121912987, rs121912989, rs1560480632, rs67707918, rs66883877
Macrocephaly	Relative macrocephaly	rs786204854, rs764333096, rs1557739557
Osteogenesis imperfecta	Osteogenesis imperfecta type III (disorder), OSTEOGENESIS IMPERFECTA, TYPE X, Osteogenesis imperfecta type 3	rs72659351, rs72659354, rs72659348, rs72659355, rs137853952, rs118203996, rs137853890, rs72659360, rs72659362, rs72659359, rs72659361, rs72659357, rs121918002, rs121918007, rs121918009, rs121918011, rs121918019, rs137853869, rs121434559, rs72659319, rs72659345, rs121912903, rs121912905, rs121912907, rs869254878, rs72658200, rs74315103, rs121912911, rs72658176, rs72656402, rs121912912, rs267606742, rs72659338, rs72645331, rs66721653, rs67368147, rs72653136, rs72653169, rs66523073, rs72656352, rs72645365, rs72667022, rs72645357, rs72656330, rs66527965, rs72645323, rs72656331, rs72667037, rs72654802, rs67682641, rs72653178, rs72653131, rs72656353, rs67828806, rs72656343, rs1906960583, rs72656314, rs67364703, rs72645347, rs72651618, rs66490707, rs72653170, rs72645320, rs137853892, rs1567856056, rs387906960, rs1555616552, rs137853865, rs137853866, rs193302872, rs193302871, rs193302873, rs137853893, rs193922137, rs72648320, rs193922138, rs193922139, rs193922140, rs193922141, rs193922143, rs193922144, rs193922145, rs193922147, rs193922148, rs193922149, rs193922151, rs193922152, rs193922154, rs72653173, rs193922155, rs193922157, rs72667023, rs193922158, rs72645328, rs193922162, rs72658154, rs193922166, rs193922167, rs193922173, rs72656387, rs193922175, rs587776916, rs398122891, rs318240762, rs372896892, rs398122834, rs749709000, rs397509383, rs397514674, rs398122518, rs398122519, rs398122520, rs387907325, rs387907333, rs387907334, rs387907354, rs387907355, rs387907356, rs387907357, rs727505392, rs786201032, rs786205217, rs786205218, rs786205219, rs786205220, rs797044559, rs794726873, rs72645353, rs869320752, rs137853943, rs797045033, rs863225043, rs869025223, rs869312908, rs878853274, rs72659347, rs72656370, rs886039693, rs67507747, rs762428889, rs72645318, rs886039880, rs369651701, rs886041866, rs886042260, rs886042286, rs886042603, rs886042897, rs72654794, rs72651642, rs140468248, rs137853944, rs1057517662, rs1057517663, rs74315111, rs72648337, rs1057518930, rs1057521085, rs1064794058, rs72658185, rs1555572249, rs67771061, rs1114167416, rs1114167417, rs72656386, rs1114167418, rs906553840, rs67729041, rs67865220, rs1114167412, rs67707918, rs68132885, rs72658119, rs72658143, rs72658150, rs72659310, rs67609234, rs1114167414, rs1114167415, rs72659325, rs67768540, rs1114167406, rs1114167405, rs1114167403, rs34940368, rs1114167402, rs72656340, rs1114167401, rs1114167400, rs72656338, rs1114167399, rs67815019, rs1114167398, rs67394386, rs1114167382, rs1114167396, rs1114167395, rs1114167381, rs1114167394, rs67445413, rs1114167380, rs1114167379, rs1114167392, rs67693970, rs1114167391, rs1114167378, rs72651661, rs1114167390, rs72651645, rs1114167389, rs1114167388, rs66555264, rs72651614, rs1114167387, rs1114167377, rs1114167375, rs1114167374, rs1114167385, rs72648326, rs72648322, rs72645369, rs1555574154, rs72645366, rs786205507, rs1114167411, rs72645356, rs72645337, rs72645334, rs72645321, rs1114167410, rs72667036, rs8179178, rs1114167408, rs1114167407, rs72667016, rs72667012, rs1114167384, rs1114167409, rs1085307634, rs1131692167, rs765659555, rs1131692326, rs1131692320, rs1135401953, rs137853883, rs1555573313, rs72667014, rs1555573621, rs1555572125, rs1260429820, rs67879854, rs1555574143, rs1328384458, rs72648343, rs1555574516, rs1555574641, rs972668240, rs72656392, rs66612022, rs66619856, rs1554395970, rs1555571755, rs1555571849, rs1555572075, rs1555572239, rs1555572458, rs1555573004, rs67543897, rs72648352, rs1555574113, rs1555574493, rs1555574497, rs1555574638, rs1555574802, rs1555571529, rs1555571647, rs1555571766, rs1555572401, rs1555572456, rs72651635, rs1555573484, rs1298621011, rs1555575086, rs1555572013, rs1555572120, rs1555572121, rs1555573039, rs1555574071, rs66664580, rs72667031, rs1555571874, rs72653151, rs72653147, rs1213427451, rs72651620, rs865999256, rs1555574144, rs1555574151, rs72645341, rs1555574496, rs1555574553, rs1555571916, rs1555178899, rs1555575370, rs1555572315, rs72645361, rs113994016, rs781272386, rs1554397369, rs1555572406, rs72651634, rs139593707, rs1555572316, rs72651640, rs1554396283, rs763159520, rs72658127, rs1553143741, rs1553143142, rs1554200383, rs1187611948, rs1554200371, rs1555572254, rs867628651, rs72653155, rs138570309, rs1410254723, rs1555573897, rs1228746935, rs72645368, rs1555574871, rs1555572640, rs1555573288, rs1555573629, rs1555575015, rs1555575889, rs1555572759, rs1555574158, rs1555574177, rs72667029, rs1555571942, rs1555574319, rs753683126, rs72651658, rs1554395470, rs1555572161, rs371243939, rs1555986267, rs1555986287, rs1555222973, rs779809838, rs1565789682, rs1557569037, rs1013320485, rs762525651, rs72656375, rs1567752926, rs1567752998, rs1567753046, rs1567753329, rs72653140, rs1567756567, rs72651644, rs1567760604, rs1567761950, rs1567763007, rs111594467, rs1567757112, rs1567759402, rs1567760123, rs67163049, rs1567756357, rs1567760736, rs1567761649, rs1567763447, rs1567763451, rs1567764387, rs1567764832, rs1567766329, rs72656326, rs1567753699, rs1567754277, rs72653168, rs72645370, rs1567762257, rs1567766338, rs72658193, rs72648357, rs1562906570, rs72659305, rs1567751388, rs1567753448, rs72651647, rs1567761800, rs1567762262, rs72648346, rs1565244847, rs1567757138, rs72656394, rs1562907287, rs1567754589, rs1598288342, rs1567855132, rs72659356, rs773269078, rs1570479611, rs762780039, rs1330779100, rs1598289920, rs72653133, rs1562906013, rs753338851, rs1570454914, rs1229143002, rs1570472113, rs137853939, rs768626850, rs1584324507, rs141011435, rs1598285120, rs72656324, rs1598288070, rs1598288593, rs1598289365, rs1598291438, rs72648330, rs1598296825, rs72648319, rs72648313, rs72645332, rs1598299070, rs1598300304, rs1473458290, rs1598285125, rs72653171, rs72653150, rs1181095991, rs1598295482, rs1598301459, rs72651667, rs1598298449, rs1597352358, rs1597355244, rs1597357740, rs1597357758, rs1597902342, rs1374482728, rs1597905563, rs1570452407, rs1570453963, rs1581634382, rs1597906442, rs1597908085, rs1597907877, rs1584316181, rs1584318953, rs72656389, rs1584319418, rs1584322737, rs1584330959, rs2586486, rs1598286543, rs72654797, rs1598288634, rs1598288656, rs1598290382, rs1598293920, rs1598295794, rs150572711, rs1598299275, rs1598300054, rs111953130, rs868166455, rs745891632, rs1021282486, rs780491808, rs1584320553, rs1598298699, rs72648321, rs1598288648, rs1598288967, rs72645352, rs1598298292, rs72645315, rs762979302, rs1598286050, rs1598301619, rs1584330396, rs72653156, rs1598295066, rs137853948, rs1598288002, rs1598289247, rs1652311421, rs1701306294, rs1906421838, rs72656351, rs72656348, rs1906537608, rs72656337, rs72656320, rs1906843530, rs1906847588, rs1906874191, rs1906878217, rs72651641, rs1907212702, rs1907330109, rs1907377731, rs1907418203, rs1907457376, rs72648333, rs1907617224, rs72667030, rs1907889665, rs1907921633, rs1908087291, rs1652352034, rs72648370, rs1555575835, rs1908083033, rs1907669327, rs112274185, rs72656327, rs1906695650, rs72645338, rs1907787005, rs1054264002, rs1791878922, rs1791894410, rs1791907178, rs369314029, rs1908050941, rs72653141, rs1907103040, rs1907351704, rs1907477506, rs1907512918, rs112042777, rs1907566530, rs1907770102, rs1791951769, rs1792108270, rs1387151592, rs72656385	21438135, 20188343, 20188343
Scoliosis	Scoliosis, unspecified	rs1057518828, rs147296805, rs758163506, rs1555613564, rs1596852902, rs1596853067, rs1596853085

Unknown
Disease name	Disease term	dbSNP ID	References
Cerebral infraction	Infarction, Middle Cerebral Artery		12374626
Cerebral thrombosis	Middle Cerebral Artery Thrombosis		12374626
Dwarfism	Dwarfism
Liver cirrhosis	Liver Cirrhosis		24321339
Liver fibrosis	Fibrosis, Liver		24321339
Lung diseases	Chronic lung disease
Micrognathism	Micrognathism
Micromelia	Micromelia
Nephrolithiasis	Nephrolithiasis
Osteopenia	Osteopenia
Respiratory distress syndrome	Respiratory Distress Syndrome, Adult		25070658