AIFM2 (AIF family member 2)

Gene

• Entrez ID: 84883
• Gene name: AIF family member 2
• Gene symbol: AIFM2
• Synonyms: AMID, FSP1, PRG3
• Chromosome: 10
• Chromosome location: 10q22.1
• Summary: This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT023966	hsa-miR-1-3p	Microarray	18668037
MIRT031880	hsa-miR-16-5p	Proteomics	18668040
MIRT046525	hsa-miR-15b-5p	CLASH	23622248
MIRT038645	hsa-miR-140-3p	CLASH	23622248
MIRT437634	hsa-miR-150-5p	Microarray, qRT-PCR	22815788
MIRT723750	hsa-miR-3168	HITS-CLIP	19536157
MIRT723749	hsa-miR-148b-5p	HITS-CLIP	19536157
MIRT723748	hsa-miR-6874-3p	HITS-CLIP	19536157
MIRT723747	hsa-miR-5584-3p	HITS-CLIP	19536157
MIRT660797	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT723746	hsa-miR-6867-3p	HITS-CLIP	19536157
MIRT723745	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT705835	hsa-miR-214-5p	HITS-CLIP	23313552
MIRT705834	hsa-miR-603	HITS-CLIP	23313552
MIRT705833	hsa-miR-6757-3p	HITS-CLIP	23313552
MIRT705832	hsa-miR-5197-3p	HITS-CLIP	23313552
MIRT705831	hsa-miR-6826-5p	HITS-CLIP	23313552
MIRT705830	hsa-miR-1224-3p	HITS-CLIP	23313552
MIRT705829	hsa-miR-342-3p	HITS-CLIP	23313552
MIRT705828	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT705827	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT705826	hsa-miR-3185	HITS-CLIP	23313552
MIRT705825	hsa-miR-4493	HITS-CLIP	23313552
MIRT705824	hsa-miR-6735-3p	HITS-CLIP	23313552
MIRT705823	hsa-miR-377-3p	HITS-CLIP	23313552
MIRT705822	hsa-miR-188-3p	HITS-CLIP	23313552
MIRT705821	hsa-miR-1260a	HITS-CLIP	23313552
MIRT705820	hsa-miR-1260b	HITS-CLIP	23313552
MIRT705819	hsa-miR-3156-3p	HITS-CLIP	23313552
MIRT705818	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT660810	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT660809	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT660808	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT660807	hsa-miR-3183	HITS-CLIP	23824327
MIRT660806	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT660805	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT437634	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT660804	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT660803	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT660802	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT660801	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT660800	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT660799	hsa-miR-374c-5p	HITS-CLIP	23824327
MIRT660798	hsa-miR-655-3p	HITS-CLIP	23824327
MIRT660797	hsa-miR-4713-5p	HITS-CLIP	23824327
MIRT660796	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT723750	hsa-miR-3168	HITS-CLIP	19536157
MIRT723749	hsa-miR-148b-5p	HITS-CLIP	19536157
MIRT723748	hsa-miR-6874-3p	HITS-CLIP	19536157
MIRT723747	hsa-miR-5584-3p	HITS-CLIP	19536157
MIRT660797	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT723746	hsa-miR-6867-3p	HITS-CLIP	19536157
MIRT723745	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT705835	hsa-miR-214-5p	HITS-CLIP	23313552
MIRT705834	hsa-miR-603	HITS-CLIP	23313552
MIRT705833	hsa-miR-6757-3p	HITS-CLIP	23313552
MIRT705832	hsa-miR-5197-3p	HITS-CLIP	23313552
MIRT705831	hsa-miR-6826-5p	HITS-CLIP	23313552
MIRT705830	hsa-miR-1224-3p	HITS-CLIP	23313552
MIRT705829	hsa-miR-342-3p	HITS-CLIP	23313552
MIRT705828	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT705827	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT705826	hsa-miR-3185	HITS-CLIP	23313552
MIRT705825	hsa-miR-4493	HITS-CLIP	23313552
MIRT705824	hsa-miR-6735-3p	HITS-CLIP	23313552
MIRT705823	hsa-miR-377-3p	HITS-CLIP	23313552
MIRT705822	hsa-miR-188-3p	HITS-CLIP	23313552
MIRT705821	hsa-miR-1260a	HITS-CLIP	23313552
MIRT705820	hsa-miR-1260b	HITS-CLIP	23313552
MIRT705819	hsa-miR-3156-3p	HITS-CLIP	23313552
MIRT705818	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT660810	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT660809	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT660808	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT660807	hsa-miR-3183	HITS-CLIP	23824327
MIRT660806	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT660805	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT437634	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT660804	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT660803	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT660802	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT660801	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT660800	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT660799	hsa-miR-374c-5p	HITS-CLIP	23824327
MIRT660798	hsa-miR-655-3p	HITS-CLIP	23824327
MIRT660797	hsa-miR-4713-5p	HITS-CLIP	23824327
MIRT660796	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT774343	hsa-miR-1202	CLIP-seq
MIRT774344	hsa-miR-1207-3p	CLIP-seq
MIRT774345	hsa-miR-1262	CLIP-seq
MIRT774346	hsa-miR-128	CLIP-seq
MIRT774347	hsa-miR-298	CLIP-seq
MIRT774348	hsa-miR-3135b	CLIP-seq
MIRT774349	hsa-miR-323b-5p	CLIP-seq
MIRT774350	hsa-miR-338-3p	CLIP-seq
MIRT774351	hsa-miR-3656	CLIP-seq
MIRT774352	hsa-miR-3678-3p	CLIP-seq
MIRT774353	hsa-miR-3678-5p	CLIP-seq
MIRT774354	hsa-miR-370	CLIP-seq
MIRT774355	hsa-miR-3926	CLIP-seq
MIRT774356	hsa-miR-3937	CLIP-seq
MIRT774357	hsa-miR-3972	CLIP-seq
MIRT774358	hsa-miR-4274	CLIP-seq
MIRT774359	hsa-miR-4437	CLIP-seq
MIRT774360	hsa-miR-4476	CLIP-seq
MIRT774361	hsa-miR-4537	CLIP-seq
MIRT774362	hsa-miR-4643	CLIP-seq
MIRT774363	hsa-miR-4649-5p	CLIP-seq
MIRT774364	hsa-miR-4653-3p	CLIP-seq
MIRT774365	hsa-miR-4659a-5p	CLIP-seq
MIRT774366	hsa-miR-4659b-5p	CLIP-seq
MIRT774367	hsa-miR-4674	CLIP-seq
MIRT774368	hsa-miR-4684-3p	CLIP-seq
MIRT774369	hsa-miR-4701-3p	CLIP-seq
MIRT774370	hsa-miR-4711-5p	CLIP-seq
MIRT774371	hsa-miR-4722-3p	CLIP-seq
MIRT774372	hsa-miR-4755-3p	CLIP-seq
MIRT774373	hsa-miR-4786-5p	CLIP-seq
MIRT774374	hsa-miR-4787-3p	CLIP-seq
MIRT774375	hsa-miR-4793-3p	CLIP-seq
MIRT774376	hsa-miR-493	CLIP-seq
MIRT774377	hsa-miR-508-5p	CLIP-seq
MIRT774378	hsa-miR-542-3p	CLIP-seq
MIRT774379	hsa-miR-548s	CLIP-seq
MIRT774380	hsa-miR-661	CLIP-seq
MIRT774381	hsa-miR-665	CLIP-seq
MIRT774382	hsa-miR-766	CLIP-seq
MIRT774383	hsa-miR-1245b-3p	CLIP-seq
MIRT774346	hsa-miR-128	CLIP-seq
MIRT774384	hsa-miR-2861	CLIP-seq
MIRT774385	hsa-miR-3140-5p	CLIP-seq
MIRT774386	hsa-miR-3613-3p	CLIP-seq
MIRT774387	hsa-miR-371-5p	CLIP-seq
MIRT774388	hsa-miR-371b-5p	CLIP-seq
MIRT774355	hsa-miR-3926	CLIP-seq
MIRT774389	hsa-miR-3942-3p	CLIP-seq
MIRT774390	hsa-miR-4659a-3p	CLIP-seq
MIRT774391	hsa-miR-4659b-3p	CLIP-seq
MIRT774392	hsa-miR-4680-3p	CLIP-seq
MIRT774393	hsa-miR-4680-5p	CLIP-seq
MIRT774373	hsa-miR-4786-5p	CLIP-seq
MIRT774394	hsa-miR-495	CLIP-seq
MIRT774395	hsa-miR-511	CLIP-seq
MIRT774379	hsa-miR-548s	CLIP-seq
MIRT774396	hsa-miR-600	CLIP-seq
MIRT774373	hsa-miR-4786-5p	CLIP-seq
MIRT2169289	hsa-miR-1227	CLIP-seq
MIRT2169290	hsa-miR-124	CLIP-seq
MIRT2169291	hsa-miR-125a-3p	CLIP-seq
MIRT2169292	hsa-miR-1260	CLIP-seq
MIRT774345	hsa-miR-1262	CLIP-seq
MIRT2169293	hsa-miR-1280	CLIP-seq
MIRT2169294	hsa-miR-1827	CLIP-seq
MIRT2169295	hsa-miR-2114	CLIP-seq
MIRT2169296	hsa-miR-3612	CLIP-seq
MIRT2169297	hsa-miR-3622a-3p	CLIP-seq
MIRT2169298	hsa-miR-3622b-3p	CLIP-seq
MIRT2169299	hsa-miR-3665	CLIP-seq
MIRT2169300	hsa-miR-3667-3p	CLIP-seq
MIRT2169301	hsa-miR-3689a-3p	CLIP-seq
MIRT2169302	hsa-miR-3689c	CLIP-seq
MIRT2169303	hsa-miR-3714	CLIP-seq
MIRT2169304	hsa-miR-3910	CLIP-seq
MIRT774355	hsa-miR-3926	CLIP-seq
MIRT2169305	hsa-miR-3934	CLIP-seq
MIRT2169306	hsa-miR-3975	CLIP-seq
MIRT2169307	hsa-miR-4252	CLIP-seq
MIRT774360	hsa-miR-4476	CLIP-seq
MIRT774363	hsa-miR-4649-5p	CLIP-seq
MIRT2169308	hsa-miR-4695-5p	CLIP-seq
MIRT774369	hsa-miR-4701-3p	CLIP-seq
MIRT2169309	hsa-miR-4728-5p	CLIP-seq
MIRT2169310	hsa-miR-4736	CLIP-seq
MIRT774373	hsa-miR-4786-5p	CLIP-seq
MIRT774375	hsa-miR-4793-3p	CLIP-seq
MIRT2169311	hsa-miR-506	CLIP-seq
MIRT774377	hsa-miR-508-5p	CLIP-seq
MIRT774378	hsa-miR-542-3p	CLIP-seq
MIRT2169312	hsa-miR-544b	CLIP-seq
MIRT774379	hsa-miR-548s	CLIP-seq
MIRT2169313	hsa-miR-650	CLIP-seq
MIRT774380	hsa-miR-661	CLIP-seq
MIRT2169314	hsa-miR-711	CLIP-seq
MIRT2169315	hsa-miR-720	CLIP-seq
MIRT2169316	hsa-miR-764	CLIP-seq
MIRT774382	hsa-miR-766	CLIP-seq
MIRT2169317	hsa-miR-890	CLIP-seq
MIRT2169318	hsa-miR-940	CLIP-seq
MIRT2384024	hsa-miR-4733-3p	CLIP-seq
MIRT2384025	hsa-miR-3657	CLIP-seq
MIRT2471845	hsa-miR-1245b-5p	CLIP-seq
MIRT2471846	hsa-miR-1254	CLIP-seq
MIRT2169291	hsa-miR-125a-3p	CLIP-seq
MIRT774345	hsa-miR-1262	CLIP-seq
MIRT2471847	hsa-miR-1273	CLIP-seq
MIRT774346	hsa-miR-128	CLIP-seq
MIRT2471848	hsa-miR-1295	CLIP-seq
MIRT2471849	hsa-miR-138	CLIP-seq
MIRT2471850	hsa-miR-146a	CLIP-seq
MIRT2471851	hsa-miR-146b-3p	CLIP-seq
MIRT2471852	hsa-miR-146b-5p	CLIP-seq
MIRT2471853	hsa-miR-183	CLIP-seq
MIRT2471854	hsa-miR-1913	CLIP-seq
MIRT2471855	hsa-miR-193a-3p	CLIP-seq
MIRT2471856	hsa-miR-193b	CLIP-seq
MIRT2471857	hsa-miR-3116	CLIP-seq
MIRT2471858	hsa-miR-3142	CLIP-seq
MIRT2471859	hsa-miR-3173-5p	CLIP-seq
MIRT2471860	hsa-miR-3194-3p	CLIP-seq
MIRT2471861	hsa-miR-323b-3p	CLIP-seq
MIRT2471862	hsa-miR-324-3p	CLIP-seq
MIRT774386	hsa-miR-3613-3p	CLIP-seq
MIRT2169297	hsa-miR-3622a-3p	CLIP-seq
MIRT2169298	hsa-miR-3622b-3p	CLIP-seq
MIRT2384025	hsa-miR-3657	CLIP-seq
MIRT2471863	hsa-miR-3680	CLIP-seq
MIRT774387	hsa-miR-371-5p	CLIP-seq
MIRT774388	hsa-miR-371b-5p	CLIP-seq
MIRT2471864	hsa-miR-3921	CLIP-seq
MIRT774355	hsa-miR-3926	CLIP-seq
MIRT2169305	hsa-miR-3934	CLIP-seq
MIRT2471865	hsa-miR-4251	CLIP-seq
MIRT2471866	hsa-miR-4323	CLIP-seq
MIRT2471867	hsa-miR-4324	CLIP-seq
MIRT2471868	hsa-miR-4329	CLIP-seq
MIRT2471869	hsa-miR-4486	CLIP-seq
MIRT774363	hsa-miR-4649-5p	CLIP-seq
MIRT2471870	hsa-miR-4653-5p	CLIP-seq
MIRT2471871	hsa-miR-4691-5p	CLIP-seq
MIRT2471872	hsa-miR-4694-3p	CLIP-seq
MIRT774369	hsa-miR-4701-3p	CLIP-seq
MIRT2471873	hsa-miR-4701-5p	CLIP-seq
MIRT2384024	hsa-miR-4733-3p	CLIP-seq
MIRT774373	hsa-miR-4786-5p	CLIP-seq
MIRT774375	hsa-miR-4793-3p	CLIP-seq
MIRT2471874	hsa-miR-4799-5p	CLIP-seq
MIRT2471875	hsa-miR-485-5p	CLIP-seq
MIRT774394	hsa-miR-495	CLIP-seq
MIRT774377	hsa-miR-508-5p	CLIP-seq
MIRT2471876	hsa-miR-522	CLIP-seq
MIRT774378	hsa-miR-542-3p	CLIP-seq
MIRT2169312	hsa-miR-544b	CLIP-seq
MIRT774379	hsa-miR-548s	CLIP-seq
MIRT2471877	hsa-miR-564	CLIP-seq
MIRT2471878	hsa-miR-588	CLIP-seq
MIRT2471879	hsa-miR-589	CLIP-seq
MIRT774380	hsa-miR-661	CLIP-seq
MIRT2169316	hsa-miR-764	CLIP-seq
MIRT774382	hsa-miR-766	CLIP-seq
MIRT2471880	hsa-miR-874	CLIP-seq
MIRT2169317	hsa-miR-890	CLIP-seq
MIRT2471845	hsa-miR-1245b-5p	CLIP-seq
MIRT2471846	hsa-miR-1254	CLIP-seq
MIRT2169291	hsa-miR-125a-3p	CLIP-seq
MIRT2471847	hsa-miR-1273	CLIP-seq
MIRT774346	hsa-miR-128	CLIP-seq
MIRT2471848	hsa-miR-1295	CLIP-seq
MIRT2471851	hsa-miR-146b-3p	CLIP-seq
MIRT2471853	hsa-miR-183	CLIP-seq
MIRT2674783	hsa-miR-186	CLIP-seq
MIRT2471854	hsa-miR-1913	CLIP-seq
MIRT2471855	hsa-miR-193a-3p	CLIP-seq
MIRT2471856	hsa-miR-193b	CLIP-seq
MIRT2471857	hsa-miR-3116	CLIP-seq
MIRT2674784	hsa-miR-3133	CLIP-seq
MIRT2471858	hsa-miR-3142	CLIP-seq
MIRT2471859	hsa-miR-3173-5p	CLIP-seq
MIRT2471860	hsa-miR-3194-3p	CLIP-seq
MIRT2471861	hsa-miR-323b-3p	CLIP-seq
MIRT2471862	hsa-miR-324-3p	CLIP-seq
MIRT774386	hsa-miR-3613-3p	CLIP-seq
MIRT2169297	hsa-miR-3622a-3p	CLIP-seq
MIRT2169298	hsa-miR-3622b-3p	CLIP-seq
MIRT2471863	hsa-miR-3680	CLIP-seq
MIRT774387	hsa-miR-371-5p	CLIP-seq
MIRT774388	hsa-miR-371b-5p	CLIP-seq
MIRT2471864	hsa-miR-3921	CLIP-seq
MIRT774355	hsa-miR-3926	CLIP-seq
MIRT2169305	hsa-miR-3934	CLIP-seq
MIRT2471865	hsa-miR-4251	CLIP-seq
MIRT2471866	hsa-miR-4323	CLIP-seq
MIRT2471868	hsa-miR-4329	CLIP-seq
MIRT2471869	hsa-miR-4486	CLIP-seq
MIRT774363	hsa-miR-4649-5p	CLIP-seq
MIRT2471870	hsa-miR-4653-5p	CLIP-seq
MIRT2471871	hsa-miR-4691-5p	CLIP-seq
MIRT2471872	hsa-miR-4694-3p	CLIP-seq
MIRT2471873	hsa-miR-4701-5p	CLIP-seq
MIRT2384024	hsa-miR-4733-3p	CLIP-seq
MIRT774373	hsa-miR-4786-5p	CLIP-seq
MIRT2471874	hsa-miR-4799-5p	CLIP-seq
MIRT774394	hsa-miR-495	CLIP-seq
MIRT2471876	hsa-miR-522	CLIP-seq
MIRT2169312	hsa-miR-544b	CLIP-seq
MIRT774379	hsa-miR-548s	CLIP-seq
MIRT2471877	hsa-miR-564	CLIP-seq
MIRT2471878	hsa-miR-588	CLIP-seq
MIRT774380	hsa-miR-661	CLIP-seq
MIRT2169316	hsa-miR-764	CLIP-seq
MIRT2471880	hsa-miR-874	CLIP-seq
MIRT2169317	hsa-miR-890	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IDA	15958387
GO:0004174	Function	Electron-transferring-flavoprotein dehydrogenase activity	IBA	21873635
GO:0004174	Function	Electron-transferring-flavoprotein dehydrogenase activity	IDA	15958387
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005615	Component	Extracellular space	HDA	22664934
GO:0005634	Component	Nucleus	ISS
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	12135761
GO:0005739	Component	Mitochondrion	IBA	21873635
GO:0005739	Component	Mitochondrion	IDA	11980907
GO:0005741	Component	Mitochondrial outer membrane	IDA	11980907
GO:0005741	Component	Mitochondrial outer membrane	TAS
GO:0005811	Component	Lipid droplet	IDA	14741744, 31634900
GO:0005829	Component	Cytosol	IDA	11980907
GO:0005886	Component	Plasma membrane	IDA	31634900
GO:0006743	Process	Ubiquinone metabolic process	IDA	31634899, 31634900
GO:0008637	Process	Apoptotic mitochondrial changes	IBA	21873635
GO:0008637	Process	Apoptotic mitochondrial changes	IDA	11980907
GO:0016021	Component	Integral component of membrane	IEA
GO:0016655	Function	Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	IDA	31634899, 31634900
GO:0022904	Process	Respiratory electron transport chain	IEA
GO:0042981	Process	Regulation of apoptotic process	TAS
GO:0043065	Process	Positive regulation of apoptotic process	IBA	21873635
GO:0043065	Process	Positive regulation of apoptotic process	IDA	11980907
GO:0050660	Function	Flavin adenine dinucleotide binding	IBA	21873635
GO:0050660	Function	Flavin adenine dinucleotide binding	IDA	15958387
GO:0110076	Process	Negative regulation of ferroptosis	IMP	31634899, 31634900
GO:1900407	Process	Regulation of cellular response to oxidative stress	ISS

Other IDs

• MIM: 605159
• HGNC: 21411
• e!Ensembl: ENSG00000042286

Protein

• UniProt ID: Q9BRQ8
• Protein name: Ferroptosis suppressor protein 1 (FSP1) (EC 1.6.5.-) (Apoptosis-inducing factor homologous mitochondrion-associated inducer of death) (AMID) (p53-responsive gene 3 protein)
• Protein function: A NAD(P)H-dependent oxidoreductase that acts as a key inhibitor of ferroptosis (PubMed:31634899, PubMed:31634900, PubMed:35922516, PubMed:39881208). At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipop
• PDB: 8JSC, 8WIK, 8YO8, 8YOQ, 8YOX
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07992	Pyr_redox_2	12 → 302	Pyridine nucleotide-disulphide oxidoreductase	Domain

• Sequence:

  MGSQVSVESGALHVVIVGGGFGGIAAASQLQALNVPFMLVDMKDSFHHNVAALRASVETG
  FAKKTFISYSVTFKDNFRQGLVVGIDLKNQMVLLQGGEALPFSHLILATGSTGPFPGKFN
  EVSSQQAAIQAYEDMVRQVQRSRFIVVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVALA
  DKELLPSVRQEVKEILLRKGVQLLLSERVSNLEELPLNEYREYIKVQTDKGTEVATNLVI
  LCTGIKINSSAYRKAFESRLASSGALRVNEHLQVEGHSNVYAIGDCADVRTPKMAYLAGL
  HANIAVANIVNSVKQRPLQAYKPGALTFLLSMGRNDGVGQISGFYVGRLMVRLTKSRDLF
  VSTSWKTMRQSPP

• Sequence length: 373

Pathways

KEGG:

p53 signaling pathway

Reactome:

TP53 Regulates Transcription of Genes Involved in Cytochrome C Release

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Rheumatoid arthritis	Rheumatoid Arthritis	rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212	30891314