Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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8417 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Syntaxin 7 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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STX7 |
SynonymsGene synonyms aliases
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- |
ChromosomeChromosome number
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6 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6q23.2 |
SummarySummary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the order |
SNPsSNP information provided by dbSNP.
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SNP ID |
Visualize variation |
Clinical significance |
Consequence |
rs864309676 |
T>G |
Likely-pathogenic |
Coding sequence variant, missense variant, non coding transcript variant |
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miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
O15400 |
Protein name |
Syntaxin-7 |
Protein function |
May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes. |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF14523 |
Syntaxin_2 |
18 → 119 |
Syntaxin-like protein |
Domain |
PF05739 |
SNARE |
201 → 253 |
SNARE domain |
Family |
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Sequence |
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Sequence length |
261 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Malformation of cortical development |
Malformations of Cortical Development, Group II |
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26395554 |
Neuronal heterotopia |
Neuronal heterotopia |
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26395554 |
Pachygyria |
Pachygyria |
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26395554 |
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