Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
8409 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Ubiquitously expressed prefoldin like chaperone |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
UXT |
SynonymsGene synonyms aliases
|
ART-27, SKP2, STAP1 |
ChromosomeChromosome number
|
X |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
Xp11.23 |
SummarySummary of gene provided in NCBI Entrez Gene.
|
The protein encoded by this gene functions as a cofactor that modulates androgen receptor-dependent transcription, and also plays a critical role in tumor necrosis factor-induced apoptosis. Expression of this gene may play a role in tumorigenesis. Alterna |
miRNAmiRNA information provided by mirtarbase database.
|
|
Transcription factors
|
Transcription factor |
Regulation |
Reference |
CREB1 |
Activation |
17761951 |
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
GO ID |
Ontology |
Definition |
Evidence |
Reference |
GO:0000122 |
Process |
Negative regulation of transcription by RNA polymerase II |
IDA |
21730289 |
GO:0000226 |
Process |
Microtubule cytoskeleton organization |
IMP |
16221885 |
GO:0000785 |
Component |
Chromatin |
IBA |
21873635 |
GO:0000922 |
Component |
Spindle pole |
IEA |
|
GO:0000930 |
Component |
Gamma-tubulin complex |
IDA |
16221885 |
GO:0003682 |
Function |
Chromatin binding |
IDA |
21730289 |
GO:0003712 |
Function |
Transcription coregulator activity |
IBA |
21873635 |
GO:0003714 |
Function |
Transcription corepressor activity |
IBA |
21873635 |
GO:0003714 |
Function |
Transcription corepressor activity |
IDA |
21730289 |
GO:0005515 |
Function |
Protein binding |
IPI |
12762840, 16221885, 17620405, 17635584, 20864032, 21730289, 24021647, 25036637, 25416956, 28106301, 28514442, 31515488, 32296183 |
GO:0005634 |
Component |
Nucleus |
IDA |
12762840, 21730289 |
GO:0005654 |
Component |
Nucleoplasm |
TAS |
|
GO:0005737 |
Component |
Cytoplasm |
IDA |
21730289 |
GO:0005813 |
Component |
Centrosome |
IDA |
16221885 |
GO:0005856 |
Component |
Cytoskeleton |
IDA |
12762840 |
GO:0006357 |
Process |
Regulation of transcription by RNA polymerase II |
IBA |
21873635 |
GO:0006915 |
Process |
Apoptotic process |
IEA |
|
GO:0007098 |
Process |
Centrosome cycle |
IMP |
16221885 |
GO:0008017 |
Function |
Microtubule binding |
TAS |
12762840 |
GO:0047497 |
Process |
Mitochondrion transport along microtubule |
TAS |
12762840 |
GO:0048487 |
Function |
Beta-tubulin binding |
IDA |
12762840 |
GO:0051015 |
Function |
Actin filament binding |
IDA |
12762840 |
GO:0070317 |
Process |
Negative regulation of G0 to G1 transition |
TAS |
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q9UBK9 |
Protein name |
Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein) |
Protein function |
Involved in gene transcription regulation (PubMed:21730289, PubMed:28106301). Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription (PubMed:11854421, PubMed:21730289). Together with URI1, associates wi |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF02996 |
Prefoldin |
28 → 148 |
Prefoldin subunit |
Coiled-coil |
|
Sequence |
|
Sequence length |
157 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
|
|
Associated diseases
|
Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Prostate cancer |
Malignant neoplasm of prostate |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
19318562 |
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Prostatic neoplasms |
Prostatic Neoplasms |
|
19318562 |
|