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UXT (ubiquitously expressed prefoldin like chaperone)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8409
Gene nameGene Name - the full gene name approved by the HGNC.
Ubiquitously expressed prefoldin like chaperone
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
UXT
SynonymsGene synonyms aliases
ART-27, SKP2, STAP1
ChromosomeChromosome number
X
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xp11.23
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene functions as a cofactor that modulates androgen receptor-dependent transcription, and also plays a critical role in tumor necrosis factor-induced apoptosis. Expression of this gene may play a role in tumorigenesis. Alterna
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT029970 hsa-miR-26b-5p Microarray 19088304
MIRT031877 hsa-miR-16-5p Proteomics 18668040
MIRT047919 hsa-miR-30c-5p CLASH 23622248
MIRT045646 hsa-miR-149-5p CLASH 23622248
Transcription factors
Transcription factor Regulation Reference
CREB1 Activation 17761951
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IDA 21730289
GO:0000226 Process Microtubule cytoskeleton organization IMP 16221885
GO:0000785 Component Chromatin IBA 21873635
GO:0000922 Component Spindle pole IEA
GO:0000930 Component Gamma-tubulin complex IDA 16221885
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9UBK9
Protein name Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein)
Protein function Involved in gene transcription regulation (PubMed:21730289, PubMed:28106301). Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription (PubMed:11854421, PubMed:21730289). Together with URI1, associates wi
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02996 Prefoldin
28 148
Prefoldin subunit
Coiled-coil
Sequence
Sequence length 157
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Transcriptional Regulation by E2F6
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 19318562
Unknown
Disease name Disease term dbSNP ID References
Prostatic neoplasms Prostatic Neoplasms 19318562

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