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TAGLN2 (transgelin 2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8407
Gene nameGene Name - the full gene name approved by the HGNC.
Transgelin 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
TAGLN2
SynonymsGene synonyms aliases
HA1756
ChromosomeChromosome number
1
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q23.2
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT002788 hsa-miR-1-3p Luciferase reporter assay 20144220
MIRT002788 hsa-miR-1-3p Luciferase reporter assay 20144220
MIRT002788 hsa-miR-1-3p pSILAC 18668040
MIRT002788 hsa-miR-1-3p Microarray 15685193
MIRT002788 hsa-miR-1-3p Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot 21304530
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0002576 Process Platelet degranulation TAS
GO:0005515 Function Protein binding IPI 21577206, 32814053
GO:0005576 Component Extracellular region TAS
GO:0005829 Component Cytosol TAS
GO:0030855 Process Epithelial cell differentiation IDA 21492153
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P37802
Protein name Transgelin-2 (Epididymis tissue protein Li 7e) (SM22-alpha homolog)
PDB 1WYM
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00307 CH
24 137
Calponin homology (CH) domain
Domain
PF00402 Calponin
174 198
Calponin family repeat
Repeat
Sequence
Sequence length 199
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Platelet degranulation
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Papillary renal carcinoma Papillary Renal Cell Carcinoma rs5030823, rs2137087134, rs121913668, rs121913669, rs121913670, rs121913671, rs121913673, rs121913243, rs786202724 15108329
Renal carcinoma Renal Cell Carcinoma, Conventional (Clear Cell) Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Collecting Duct Carcinoma of the Kidney rs121913668, rs121913670, rs121913243, rs786202724 15108329
Unknown
Disease name Disease term dbSNP ID References
Chromophobe carcinoma Chromophobe Renal Cell Carcinoma rs137853247 15108329
Liver carcinoma Liver carcinoma 21472284
Liver cirrhosis Liver Cirrhosis 25226513
Liver fibrosis Fibrosis, Liver 25226513

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