Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
83940 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
TatD DNase domain containing 1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
TATDN1 |
SynonymsGene synonyms aliases
|
CDA11 |
ChromosomeChromosome number
|
8 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
8q24.13 |
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
GO ID |
Ontology |
Definition |
Evidence |
Reference |
GO:0005515 |
Function |
Protein binding |
IPI |
15846844 |
GO:0005654 |
Component |
Nucleoplasm |
IDA |
|
GO:0006259 |
Process |
DNA metabolic process |
IEA |
|
GO:0008296 |
Function |
3'-5'-exodeoxyribonuclease activity |
IBA |
21873635 |
GO:0016888 |
Function |
Endodeoxyribonuclease activity, producing 5'-phosphomonoesters |
IEA |
|
GO:0046872 |
Function |
Metal ion binding |
IEA |
|
GO:0090305 |
Process |
Nucleic acid phosphodiester bond hydrolysis |
IEA |
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q6P1N9 |
Protein name |
Deoxyribonuclease TATDN1 (EC 3.1.21.-) (Hepatocarcinoma high expression protein) |
Protein function |
Deoxyribonuclease which catalyzes (in vitro) the decatenation of kinetoplast DNA, which are circular DNA catenated to each other, producing linear DNA molecules (By similarity). Plays an important role in chromosomal segregation and cell cycle p |
PDB |
2XIO
,
8EFG
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF01026 |
TatD_DNase |
7 → 294 |
TatD related DNase |
Domain |
|
Sequence |
|
Sequence length |
297 |
Interactions |
View interactions |
Associated diseases
|
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Liver carcinoma |
Liver carcinoma |
|
21472284 |
|