GediPNet logo

ANGPTL6 (angiopoietin like 6)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
83854
Gene nameGene Name - the full gene name approved by the HGNC.
Angiopoietin like 6
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ANGPTL6
SynonymsGene synonyms aliases
AGF, ARP5
ChromosomeChromosome number
19
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.2
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT2171288 hsa-miR-128 CLIP-seq
MIRT2171289 hsa-miR-1915 CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001525 Process Angiogenesis IEA
GO:0005102 Function Signaling receptor binding IBA 21873635
GO:0005615 Component Extracellular space IBA 21873635
GO:0030141 Component Secretory granule IEA
GO:0030154 Process Cell differentiation IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q8NI99
Protein name Angiopoietin-related protein 6 (Angiopoietin-like protein 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5)
Protein function May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity
PDB 6Y43
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00147 Fibrinogen_C
256 468
Fibrinogen beta and gamma chains, C-terminal globular domain
Domain
Sequence
MGKPWLRALQLLLLLGASWARAGAPRCTYTFVLPPQKFTGAVCWSGPASTRATPEAANAS
ELAALRMRVGRHEELLRELQRLAAADGAVAGEVRALRKESRGLSARLGQLRAQLQHEAGP
GAGPGADLGAEPAAALALLGERVLNASAEAQRAAARFHQLDVKFRELAQLVTQQSSLIAR
LERLCPGGAGGQQQVLPPPPLVPVVPVRLVGSTSDTSRMLDPAPEPQRDQTQRQQEPMAS
PMPAGHPAVPTKPVGPWQDCAEARQAGHEQSGVYELRVGRHVVSVWCEQQLEGGGWTVIQ
RRQDGSVNFFTTWQHYKAGFGRPDGEYWLGLEPVYQLTSRGDHELLVLLEDWGGRGARAH
YDGFSLEPESDHYRLRLGQYHGDAGDSLSWHNDKPFSTVDRDRDSYSGNCALYQRGGWWY
HACAHSNLNGVWHHGGHYRSRYQDGVYWAEFRGGAYSLRKAAMLIRPL
KL
Sequence length 470
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Aortic dissection Dissection of aorta rs1553507345
Hypertension Hypertensive disease rs13306026, rs13333226
Intracranial aneurysm ANEURYSM, INTRACRANIAL BERRY, 1 (disorder) rs1594095223 29304371
Unknown
Disease name Disease term dbSNP ID References
Atherosclerosis Atherosclerosis rs699947, rs59439148
Cerebral saccular aneurysm Familial cerebral saccular aneurysm
Encephalomalacia Encephalomalacia
Liver carcinoma Liver carcinoma 28284560

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412