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CALN1 (calneuron 1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
83698
Gene nameGene Name - the full gene name approved by the HGNC.
Calneuron 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CALN1
SynonymsGene synonyms aliases
CABP8
ChromosomeChromosome number
7
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7q11.22
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants.
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019343 hsa-miR-148b-3p Microarray 17612493
MIRT053772 hsa-miR-675-5p Luciferase reporter assay, Microarray, qRT-PCR, Western blot 24810858
MIRT723394 hsa-miR-7153-3p HITS-CLIP 19536157
MIRT723393 hsa-miR-3127-3p HITS-CLIP 19536157
MIRT723392 hsa-miR-6756-3p HITS-CLIP 19536157
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005509 Function Calcium ion binding IEA
GO:0005515 Function Protein binding IPI 30073165, 32296183
GO:0005886 Component Plasma membrane IEA
GO:0016021 Component Integral component of membrane IEA
GO:0032588 Component Trans-Golgi network membrane IDA 19338761
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9BXU9
Protein name Calcium-binding protein 8 (CaBP8) (Calneuron I) (Calneuron-1)
Protein function Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13499 EF-hand_7
38 102
EF-hand domain pair
Domain
Sequence
MRLPEQPGEGKPENEKKGDGGALGGGEEPPRSQAPDFPTWEKMPFHHVTAGLLYKGNYLN
RSLSAGSDSEQLANISVEELDEIREAFRVLDRDGNGFISKQE
LGMAMRSLGYMPSEVELA
IIMQRLDMDGDGQVDFDEFMTILGPKLVSSEGRDGFLGNTIDSIFWQFDMQRITLEELKH
ILYHAFRDHLTMKDIENIIINEEESLNETSGNCQTEFEGVHSQKQNRQTCVRKSLICAFA
MAFIISVMLIAANQILRSGME
Sequence length 261
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 30285260, 26198764, 31374203, 28991256

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