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H3C2 (H3 clustered histone 2)
Gene
Gene Gene ontology Other IDs Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8358
Gene nameGene Name - the full gene name approved by the HGNC.
H3 clustered histone 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
H3C2
SynonymsGene synonyms aliases
H3/l, H3C1, H3C10, H3C11, H3C12, H3C3, H3C4, H3C6, H3C7, H3C8, H3FL, HIST1H3B
ChromosomeChromosome number
6
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6p22.2
SummarySummary of gene provided in NCBI Entrez Gene.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the f
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0000183 Process RDNA heterochromatin assembly TAS
GO:0000228 Component Nuclear chromosome IDA 14718166
GO:0000786 Component Nucleosome IDA 20498094, 21636898, 24699735, 25615412
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 10949293, 10975519, 12489984, 12540855, 16189514, 16246723, 16415788, 16603238, 16946699, 17157298, 18292755, 18418070, 19410544, 19498464, 19766566, 20080577, 20498094, 20541251, 20739937, 20871592, 21685874, 22720776, 23142979, 23275563, 24590075, 24606918, 24788516, 24981860, 254
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Pathways Associated diseases
MIM
HGNC
e!Ensembl
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene Gene ontology Other IDs Pathways Associated diseases
 
KEGG
  
Reactome
  Neutrophil extracellular trap formation
Alcoholism
Shigellosis
Transcriptional misregulation in cancer
Systemic lupus erythematosus 		  Interleukin-7 signaling
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
HDACs deacetylate histones
PKMTs methylate histone lysines
HDMs demethylate histones
HATs acetylate histones
RMTs methylate histone arginines
Chromatin modifying enzymes
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Estrogen-dependent gene expression
HCMV Early Events
HCMV Late Events
Amyloid fiber formation
Factors involved in megakaryocyte development and platelet production
Associated diseases
Gene Gene ontology Other IDs Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Glioblastoma Glioblastoma, Glioblastoma Multiforme rs121913500, rs886042842, rs1555138291, rs1558518449, rs1567176006, rs1558650888 22286216
Glioma Glioma, mixed gliomas, Malignant Glioma rs121909219, rs121909224, rs587776667, rs587776671, rs121909239, rs121909241, rs28933368, rs121913500, rs55863639, rs786201995, rs786202517, rs786201044, rs398123317, rs1057518425, rs121913499, rs1060500122, rs781647403, rs1060500126, rs1554897889, rs1114167629, rs1114167656, rs587782603, rs1554893824, rs1554900615, rs1564568660, rs786204900, rs762518389, rs1339631701 22286216
Unknown
Disease name Disease term dbSNP ID References
Giant cell glioblastoma Giant Cell Glioblastoma 22286216
Gout Gout 23263486, 21768215
Gouty arthritis Arthritis, Gouty 21768215, 23263486

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