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CDCA3 (cell division cycle associated 3)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
83461
Gene nameGene Name - the full gene name approved by the HGNC.
Cell division cycle associated 3
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CDCA3
SynonymsGene synonyms aliases
GRCC8, TOME-1, TOME1
ChromosomeChromosome number
12
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.31
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT029492 hsa-miR-26b-5p Microarray 19088304
MIRT051450 hsa-let-7e-5p CLASH 23622248
MIRT044752 hsa-miR-320a CLASH 23622248
MIRT451819 hsa-miR-3936 PAR-CLIP 23446348
MIRT451818 hsa-miR-3154 PAR-CLIP 23446348
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16189514, 25416956, 28514442, 31515488, 32296183
GO:0005829 Component Cytosol IEA
GO:0005912 Component Adherens junction IDA 25468996
GO:0007049 Process Cell cycle IEA
GO:0008150 Process Biological_process ND
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q99618
Protein name Cell division cycle-associated protein 3 (Gene-rich cluster protein C8) (Trigger of mitotic entry protein 1) (TOME-1)
Protein function F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity).
Family and domains
Sequence
MGSAKSVPVTPARPPPHNKHLARVADPRSPSAGILRTPIQVESSPQPGLPAGEQLEGLKH
AQDSDPRSPTLGIARTPMKTSSGDPPSPLVKQLSEVFETEDSKSNLPPEPVLPPEAPLSS
ELDLPLGTQLSVEEQMPPWNQTEFPSKQVFSKEEARQPTETPVASQSSDKPSRDPETPRS
SGSMRNRWKPNSSKVLGRSPLTILQDDNSPGTLTLRQGKRPSPLSENVSELKEGAILGTG
RLLKTGGRAWEQGQDHDKENQHFPLVES
Sequence length 268
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Myopia Myopia rs387907109, rs146936371, rs587776903, rs786205127, rs398122836, rs199624584, rs587777625, rs786205216, rs758872875, rs764211125, rs1135402746, rs765658563, rs1555941129, rs1555941116, rs199923805, rs782555528, rs1554862601, rs1586620121, rs1387950081, rs2051026773, rs1422332023 27182965
Unknown
Disease name Disease term dbSNP ID References
Liver carcinoma Liver carcinoma 28284560
Night blindness, congenital stationary NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1H

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