PCDH11Y (protocadherin 11 Y-linked)

Gene

• Entrez ID: 83259
• Gene name: Protocadherin 11 Y-linked
• Gene symbol: PCDH11Y
• Synonyms: PCDH-PC, PCDH22, PCDHX, PCDHY
• Chromosome: Y
• Chromosome location: Yp11.2
• Summary: This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of th

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT655355	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT655354	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT655353	hsa-miR-324-5p	HITS-CLIP	23824327
MIRT655352	hsa-miR-4775	HITS-CLIP	23824327
MIRT655351	hsa-miR-432-3p	HITS-CLIP	23824327
MIRT555821	hsa-miR-383-5p	PAR-CLIP	20371350
MIRT555820	hsa-miR-5694	PAR-CLIP	20371350
MIRT555819	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT555818	hsa-miR-3935	PAR-CLIP	20371350
MIRT555817	hsa-miR-376a-2-5p	PAR-CLIP	20371350
MIRT555816	hsa-miR-567	PAR-CLIP	20371350
MIRT555815	hsa-miR-223-5p	PAR-CLIP	20371350
MIRT555814	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT555813	hsa-miR-297	PAR-CLIP	20371350
MIRT555812	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT555821	hsa-miR-383-5p	PAR-CLIP	21572407
MIRT555820	hsa-miR-5694	PAR-CLIP	21572407
MIRT555819	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT555818	hsa-miR-3935	PAR-CLIP	21572407
MIRT555817	hsa-miR-376a-2-5p	PAR-CLIP	21572407
MIRT555816	hsa-miR-567	PAR-CLIP	21572407
MIRT555815	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT555814	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT555813	hsa-miR-297	PAR-CLIP	21572407
MIRT555812	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT555815	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT555813	hsa-miR-297	HITS-CLIP	27418678
MIRT555817	hsa-miR-376a-2-5p	HITS-CLIP	27418678
MIRT555821	hsa-miR-383-5p	HITS-CLIP	27418678
MIRT555818	hsa-miR-3935	HITS-CLIP	27418678
MIRT555819	hsa-miR-511-3p	HITS-CLIP	27418678
MIRT555816	hsa-miR-567	HITS-CLIP	27418678
MIRT555820	hsa-miR-5694	HITS-CLIP	27418678
MIRT555812	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT555814	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT655355	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT655354	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT655353	hsa-miR-324-5p	HITS-CLIP	23824327
MIRT655352	hsa-miR-4775	HITS-CLIP	23824327
MIRT655351	hsa-miR-432-3p	HITS-CLIP	23824327
MIRT555821	hsa-miR-383-5p	PAR-CLIP	20371350
MIRT555820	hsa-miR-5694	PAR-CLIP	20371350
MIRT555819	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT555818	hsa-miR-3935	PAR-CLIP	20371350
MIRT555817	hsa-miR-376a-2-5p	PAR-CLIP	20371350
MIRT555816	hsa-miR-567	PAR-CLIP	20371350
MIRT555815	hsa-miR-223-5p	PAR-CLIP	20371350
MIRT555814	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT555813	hsa-miR-297	PAR-CLIP	20371350
MIRT555812	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT555821	hsa-miR-383-5p	PAR-CLIP	21572407
MIRT555820	hsa-miR-5694	PAR-CLIP	21572407
MIRT555819	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT555818	hsa-miR-3935	PAR-CLIP	21572407
MIRT555817	hsa-miR-376a-2-5p	PAR-CLIP	21572407
MIRT555816	hsa-miR-567	PAR-CLIP	21572407
MIRT555815	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT555814	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT555813	hsa-miR-297	PAR-CLIP	21572407
MIRT555812	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT1216703	hsa-miR-1307	CLIP-seq
MIRT1216704	hsa-miR-4284	CLIP-seq
MIRT1216705	hsa-miR-4638-5p	CLIP-seq
MIRT1216706	hsa-miR-566	CLIP-seq
MIRT1216707	hsa-miR-122	CLIP-seq
MIRT1216703	hsa-miR-1307	CLIP-seq
MIRT1216708	hsa-miR-3135b	CLIP-seq
MIRT1216709	hsa-miR-3652	CLIP-seq
MIRT1216710	hsa-miR-4430	CLIP-seq
MIRT1216705	hsa-miR-4638-5p	CLIP-seq
MIRT1216706	hsa-miR-566	CLIP-seq
MIRT1216711	hsa-miR-1243	CLIP-seq
MIRT1216712	hsa-miR-186	CLIP-seq
MIRT1216713	hsa-miR-3171	CLIP-seq
MIRT1216714	hsa-miR-3654	CLIP-seq
MIRT1216715	hsa-miR-3668	CLIP-seq
MIRT1216716	hsa-miR-374a	CLIP-seq
MIRT1216717	hsa-miR-374b	CLIP-seq
MIRT1216718	hsa-miR-4318	CLIP-seq
MIRT1216719	hsa-miR-4477a	CLIP-seq
MIRT1216720	hsa-miR-4477b	CLIP-seq
MIRT1216721	hsa-miR-4652-3p	CLIP-seq
MIRT1216722	hsa-miR-4693-5p	CLIP-seq
MIRT1216723	hsa-miR-4778-5p	CLIP-seq
MIRT1216724	hsa-miR-656	CLIP-seq
MIRT1216725	hsa-miR-668	CLIP-seq
MIRT1216726	hsa-miR-671-5p	CLIP-seq
MIRT1216727	hsa-miR-889	CLIP-seq
MIRT1216728	hsa-miR-892a	CLIP-seq
MIRT1216712	hsa-miR-186	CLIP-seq
MIRT2062555	hsa-miR-2276	CLIP-seq
MIRT2062556	hsa-miR-3607-5p	CLIP-seq
MIRT2062557	hsa-miR-4274	CLIP-seq
MIRT2062558	hsa-miR-4282	CLIP-seq
MIRT2062559	hsa-miR-455-5p	CLIP-seq
MIRT1216722	hsa-miR-4693-5p	CLIP-seq
MIRT2062560	hsa-miR-4696	CLIP-seq
MIRT2062561	hsa-miR-550a	CLIP-seq
MIRT2062562	hsa-miR-627	CLIP-seq
MIRT2290964	hsa-miR-1272	CLIP-seq
MIRT2290965	hsa-miR-1276	CLIP-seq
MIRT2290966	hsa-miR-1296	CLIP-seq
MIRT2290967	hsa-miR-137	CLIP-seq
MIRT2290968	hsa-miR-2277-3p	CLIP-seq
MIRT2290969	hsa-miR-25	CLIP-seq
MIRT2290970	hsa-miR-2909	CLIP-seq
MIRT2290971	hsa-miR-3065-5p	CLIP-seq
MIRT2290972	hsa-miR-3182	CLIP-seq
MIRT2290973	hsa-miR-32	CLIP-seq
MIRT2290974	hsa-miR-3613-3p	CLIP-seq
MIRT2290975	hsa-miR-363	CLIP-seq
MIRT2290976	hsa-miR-367	CLIP-seq
MIRT2290977	hsa-miR-3682-3p	CLIP-seq
MIRT2290978	hsa-miR-4311	CLIP-seq
MIRT2290979	hsa-miR-4325	CLIP-seq
MIRT2290980	hsa-miR-4436b-3p	CLIP-seq
MIRT2290981	hsa-miR-4636	CLIP-seq
MIRT2290982	hsa-miR-4680-5p	CLIP-seq
MIRT2290983	hsa-miR-4711-3p	CLIP-seq
MIRT2290984	hsa-miR-4744	CLIP-seq
MIRT2290985	hsa-miR-4761-3p	CLIP-seq
MIRT2290986	hsa-miR-548ac	CLIP-seq
MIRT2290987	hsa-miR-548ae	CLIP-seq
MIRT2290988	hsa-miR-548aj	CLIP-seq
MIRT2290989	hsa-miR-548am	CLIP-seq
MIRT2290990	hsa-miR-548d-3p	CLIP-seq
MIRT2290991	hsa-miR-548x	CLIP-seq
MIRT2290992	hsa-miR-548z	CLIP-seq
MIRT2290993	hsa-miR-570	CLIP-seq
MIRT2290994	hsa-miR-582-5p	CLIP-seq
MIRT2290995	hsa-miR-583	CLIP-seq
MIRT2290996	hsa-miR-618	CLIP-seq
MIRT2290997	hsa-miR-922	CLIP-seq
MIRT2290998	hsa-miR-92a	CLIP-seq
MIRT2290999	hsa-miR-92b	CLIP-seq
MIRT1216711	hsa-miR-1243	CLIP-seq
MIRT1216712	hsa-miR-186	CLIP-seq
MIRT1216714	hsa-miR-3654	CLIP-seq
MIRT1216718	hsa-miR-4318	CLIP-seq
MIRT2392192	hsa-miR-4668-3p	CLIP-seq
MIRT1216722	hsa-miR-4693-5p	CLIP-seq
MIRT1216726	hsa-miR-671-5p	CLIP-seq
MIRT1216728	hsa-miR-892a	CLIP-seq
MIRT1216707	hsa-miR-122	CLIP-seq
MIRT2588601	hsa-miR-1270	CLIP-seq
MIRT2588602	hsa-miR-1273f	CLIP-seq
MIRT2588603	hsa-miR-1281	CLIP-seq
MIRT2588604	hsa-miR-129-5p	CLIP-seq
MIRT1216703	hsa-miR-1307	CLIP-seq
MIRT2588605	hsa-miR-1976	CLIP-seq
MIRT2062555	hsa-miR-2276	CLIP-seq
MIRT1216708	hsa-miR-3135b	CLIP-seq
MIRT2588606	hsa-miR-3149	CLIP-seq
MIRT2588607	hsa-miR-3199	CLIP-seq
MIRT2588608	hsa-miR-3591-5p	CLIP-seq
MIRT1216709	hsa-miR-3652	CLIP-seq
MIRT2588609	hsa-miR-3658	CLIP-seq
MIRT2588610	hsa-miR-3681	CLIP-seq
MIRT2588611	hsa-miR-3913-3p	CLIP-seq
MIRT2588612	hsa-miR-4258	CLIP-seq
MIRT2588613	hsa-miR-4279	CLIP-seq
MIRT1216704	hsa-miR-4284	CLIP-seq
MIRT2588614	hsa-miR-4426	CLIP-seq
MIRT1216710	hsa-miR-4430	CLIP-seq
MIRT2588615	hsa-miR-4438	CLIP-seq
MIRT2588616	hsa-miR-4460	CLIP-seq
MIRT2588617	hsa-miR-4532	CLIP-seq
MIRT1216705	hsa-miR-4638-5p	CLIP-seq
MIRT2588618	hsa-miR-4647	CLIP-seq
MIRT2588619	hsa-miR-4662b	CLIP-seq
MIRT2588620	hsa-miR-4683	CLIP-seq
MIRT2588621	hsa-miR-4707-3p	CLIP-seq
MIRT2588622	hsa-miR-4722-3p	CLIP-seq
MIRT2588623	hsa-miR-4727-3p	CLIP-seq
MIRT2588624	hsa-miR-4735-5p	CLIP-seq
MIRT2588625	hsa-miR-4740-3p	CLIP-seq
MIRT2588626	hsa-miR-5095	CLIP-seq
MIRT1216706	hsa-miR-566	CLIP-seq
MIRT2588627	hsa-miR-620	CLIP-seq
MIRT1216707	hsa-miR-122	CLIP-seq
MIRT2588601	hsa-miR-1270	CLIP-seq
MIRT2588603	hsa-miR-1281	CLIP-seq
MIRT2588604	hsa-miR-129-5p	CLIP-seq
MIRT1216703	hsa-miR-1307	CLIP-seq
MIRT2588605	hsa-miR-1976	CLIP-seq
MIRT2062555	hsa-miR-2276	CLIP-seq
MIRT1216708	hsa-miR-3135b	CLIP-seq
MIRT2588606	hsa-miR-3149	CLIP-seq
MIRT2588607	hsa-miR-3199	CLIP-seq
MIRT2588608	hsa-miR-3591-5p	CLIP-seq
MIRT1216709	hsa-miR-3652	CLIP-seq
MIRT2588610	hsa-miR-3681	CLIP-seq
MIRT2588612	hsa-miR-4258	CLIP-seq
MIRT2588613	hsa-miR-4279	CLIP-seq
MIRT1216704	hsa-miR-4284	CLIP-seq
MIRT1216710	hsa-miR-4430	CLIP-seq
MIRT2588615	hsa-miR-4438	CLIP-seq
MIRT2588616	hsa-miR-4460	CLIP-seq
MIRT2588617	hsa-miR-4532	CLIP-seq
MIRT1216705	hsa-miR-4638-5p	CLIP-seq
MIRT2588620	hsa-miR-4683	CLIP-seq
MIRT2588621	hsa-miR-4707-3p	CLIP-seq
MIRT2588622	hsa-miR-4722-3p	CLIP-seq
MIRT2588623	hsa-miR-4727-3p	CLIP-seq
MIRT2588624	hsa-miR-4735-5p	CLIP-seq
MIRT2588625	hsa-miR-4740-3p	CLIP-seq
MIRT2588626	hsa-miR-5095	CLIP-seq
MIRT1216706	hsa-miR-566	CLIP-seq
MIRT2588627	hsa-miR-620	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0005887	Component	Integral component of plasma membrane	IBA	21873635
GO:0007155	Process	Cell adhesion	IBA	21873635
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA

Other IDs

• MIM: 400022
• HGNC: 15813
• e!Ensembl: ENSG00000099715

Protein

• UniProt ID: Q9BZA8
• Protein name: Protocadherin-11 Y-linked (Protocadherin-11) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC) (Protocadherin-22)
• Protein function: Potential calcium-dependent cell-adhesion protein.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08266	Cadherin_2	57 → 147	Cadherin-like	Domain
  PF00028	Cadherin	176 → 272	Cadherin domain	Domain
  PF00028	Cadherin	286 → 378	Cadherin domain	Domain
  PF00028	Cadherin	398 → 489	Cadherin domain	Domain
  PF00028	Cadherin	503 → 593	Cadherin domain	Domain
  PF00028	Cadherin	607 → 696	Cadherin domain	Domain
  PF00028	Cadherin	714 → 805	Cadherin domain	Domain
  PF08374	Protocadherin	807 → 1030	Protocadherin	Family

• Sequence:

  MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY
  TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG
  ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI
  PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD
  REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV
  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL
  ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK
  DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ
  SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD
  APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP
  VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN
  ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS
  TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR
  VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS
  DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK
  KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF
  KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP
  YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL
  PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG
  HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL
  CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL
  HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA
  PRQQARPSRGDSPIMETHPL

• Sequence length: 1340

Pathways

KEGG:

Virion - Lassa virus and SFTS virus

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	16637074

Unknown
Disease name	Disease term	dbSNP ID	References
Prostatic neoplasms	Prostatic Neoplasms		16637074