ZNF93 (zinc finger protein 93)

Gene

• Entrez ID: 81931
• Gene name: Zinc finger protein 93
• Gene symbol: ZNF93
• Synonyms: HPF34, HTF34, TF34, ZNF505
• Chromosome: 19
• Chromosome location: 19p12

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT525209	hsa-miR-3609	PAR-CLIP	22012620
MIRT525208	hsa-miR-548ah-5p	PAR-CLIP	22012620
MIRT525207	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT525206	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT525205	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT525204	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT525203	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT525202	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT525201	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT525200	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT525199	hsa-miR-4796-3p	PAR-CLIP	22012620
MIRT525198	hsa-miR-142-5p	PAR-CLIP	22012620
MIRT525197	hsa-miR-5590-3p	PAR-CLIP	22012620
MIRT525196	hsa-miR-1180-5p	PAR-CLIP	22012620
MIRT525195	hsa-miR-7114-3p	PAR-CLIP	22012620
MIRT525194	hsa-miR-548aj-5p	PAR-CLIP	22012620
MIRT525193	hsa-miR-548f-5p	PAR-CLIP	22012620
MIRT525192	hsa-miR-548g-5p	PAR-CLIP	22012620
MIRT525191	hsa-miR-548x-5p	PAR-CLIP	22012620
MIRT525190	hsa-miR-1468-3p	PAR-CLIP	22012620
MIRT525189	hsa-miR-7973	PAR-CLIP	22012620
MIRT525188	hsa-miR-548aw	PAR-CLIP	22012620
MIRT525209	hsa-miR-3609	PAR-CLIP	22012620
MIRT525208	hsa-miR-548ah-5p	PAR-CLIP	22012620
MIRT525207	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT525206	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT525205	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT525204	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT525203	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT525202	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT525201	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT525200	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT525199	hsa-miR-4796-3p	PAR-CLIP	22012620
MIRT525198	hsa-miR-142-5p	PAR-CLIP	22012620
MIRT525197	hsa-miR-5590-3p	PAR-CLIP	22012620
MIRT525196	hsa-miR-1180-5p	PAR-CLIP	22012620
MIRT525195	hsa-miR-7114-3p	PAR-CLIP	22012620
MIRT525194	hsa-miR-548aj-5p	PAR-CLIP	22012620
MIRT525193	hsa-miR-548f-5p	PAR-CLIP	22012620
MIRT525192	hsa-miR-548g-5p	PAR-CLIP	22012620
MIRT525191	hsa-miR-548x-5p	PAR-CLIP	22012620
MIRT525190	hsa-miR-1468-3p	PAR-CLIP	22012620
MIRT525189	hsa-miR-7973	PAR-CLIP	22012620
MIRT525188	hsa-miR-548aw	PAR-CLIP	22012620
MIRT1542672	hsa-miR-1193	CLIP-seq
MIRT1542673	hsa-miR-1224-5p	CLIP-seq
MIRT1542674	hsa-miR-1238	CLIP-seq
MIRT1542675	hsa-miR-1255a	CLIP-seq
MIRT1542676	hsa-miR-1255b	CLIP-seq
MIRT1542677	hsa-miR-1265	CLIP-seq
MIRT1542678	hsa-miR-1294	CLIP-seq
MIRT1542679	hsa-miR-145	CLIP-seq
MIRT1542680	hsa-miR-1825	CLIP-seq
MIRT1542681	hsa-miR-1911	CLIP-seq
MIRT1542682	hsa-miR-199a-5p	CLIP-seq
MIRT1542683	hsa-miR-199b-5p	CLIP-seq
MIRT1542684	hsa-miR-221	CLIP-seq
MIRT1542685	hsa-miR-222	CLIP-seq
MIRT1542686	hsa-miR-3064-3p	CLIP-seq
MIRT1542687	hsa-miR-3119	CLIP-seq
MIRT1542688	hsa-miR-3122	CLIP-seq
MIRT1542689	hsa-miR-3174	CLIP-seq
MIRT1542690	hsa-miR-3182	CLIP-seq
MIRT1542691	hsa-miR-323-3p	CLIP-seq
MIRT1542692	hsa-miR-3659	CLIP-seq
MIRT1542693	hsa-miR-3691-5p	CLIP-seq
MIRT1542694	hsa-miR-377	CLIP-seq
MIRT1542695	hsa-miR-3913-5p	CLIP-seq
MIRT1542696	hsa-miR-409-5p	CLIP-seq
MIRT1542697	hsa-miR-412	CLIP-seq
MIRT1542698	hsa-miR-4276	CLIP-seq
MIRT1542699	hsa-miR-4316	CLIP-seq
MIRT1542700	hsa-miR-4474-3p	CLIP-seq
MIRT1542701	hsa-miR-4491	CLIP-seq
MIRT1542702	hsa-miR-4493	CLIP-seq
MIRT1542703	hsa-miR-450b-3p	CLIP-seq
MIRT1542704	hsa-miR-4635	CLIP-seq
MIRT1542705	hsa-miR-4657	CLIP-seq
MIRT1542706	hsa-miR-4658	CLIP-seq
MIRT1542707	hsa-miR-4659a-3p	CLIP-seq
MIRT1542708	hsa-miR-4659b-3p	CLIP-seq
MIRT1542709	hsa-miR-4715-3p	CLIP-seq
MIRT1542710	hsa-miR-4727-5p	CLIP-seq
MIRT1542711	hsa-miR-4751	CLIP-seq
MIRT1542712	hsa-miR-4752	CLIP-seq
MIRT1542713	hsa-miR-4764-5p	CLIP-seq
MIRT1542714	hsa-miR-4769-3p	CLIP-seq
MIRT1542715	hsa-miR-4776-3p	CLIP-seq
MIRT1542716	hsa-miR-4797-5p	CLIP-seq
MIRT1542717	hsa-miR-548v	CLIP-seq
MIRT1542718	hsa-miR-574-5p	CLIP-seq
MIRT1542719	hsa-miR-603	CLIP-seq
MIRT1542720	hsa-miR-644	CLIP-seq
MIRT1542721	hsa-miR-765	CLIP-seq
MIRT1542722	hsa-miR-769-3p	CLIP-seq
MIRT2163701	hsa-miR-1184	CLIP-seq
MIRT2163702	hsa-miR-1205	CLIP-seq
MIRT2163703	hsa-miR-1245	CLIP-seq
MIRT2163704	hsa-miR-142-3p	CLIP-seq
MIRT1542681	hsa-miR-1911	CLIP-seq
MIRT2163705	hsa-miR-2052	CLIP-seq
MIRT1542686	hsa-miR-3064-3p	CLIP-seq
MIRT1542687	hsa-miR-3119	CLIP-seq
MIRT2163706	hsa-miR-3158-5p	CLIP-seq
MIRT1542689	hsa-miR-3174	CLIP-seq
MIRT2163707	hsa-miR-3184	CLIP-seq
MIRT2163708	hsa-miR-3607-3p	CLIP-seq
MIRT1542692	hsa-miR-3659	CLIP-seq
MIRT2163709	hsa-miR-3674	CLIP-seq
MIRT1542694	hsa-miR-377	CLIP-seq
MIRT1542697	hsa-miR-412	CLIP-seq
MIRT2163710	hsa-miR-423-5p	CLIP-seq
MIRT1542698	hsa-miR-4276	CLIP-seq
MIRT1542700	hsa-miR-4474-3p	CLIP-seq
MIRT2163711	hsa-miR-4484	CLIP-seq
MIRT1542702	hsa-miR-4493	CLIP-seq
MIRT2163712	hsa-miR-4527	CLIP-seq
MIRT1542704	hsa-miR-4635	CLIP-seq
MIRT2163713	hsa-miR-4650-5p	CLIP-seq
MIRT1542706	hsa-miR-4658	CLIP-seq
MIRT2163714	hsa-miR-4687-3p	CLIP-seq
MIRT2163715	hsa-miR-4694-3p	CLIP-seq
MIRT1542709	hsa-miR-4715-3p	CLIP-seq
MIRT2163716	hsa-miR-4753-5p	CLIP-seq
MIRT2163717	hsa-miR-4763-5p	CLIP-seq
MIRT1542715	hsa-miR-4776-3p	CLIP-seq
MIRT2163718	hsa-miR-4802-3p	CLIP-seq
MIRT2163719	hsa-miR-522	CLIP-seq
MIRT2163720	hsa-miR-548al	CLIP-seq
MIRT2163721	hsa-miR-548an	CLIP-seq
MIRT1542718	hsa-miR-574-5p	CLIP-seq
MIRT1542720	hsa-miR-644	CLIP-seq
MIRT2163722	hsa-miR-877	CLIP-seq
MIRT1542673	hsa-miR-1224-5p	CLIP-seq
MIRT1542675	hsa-miR-1255a	CLIP-seq
MIRT1542676	hsa-miR-1255b	CLIP-seq
MIRT1542678	hsa-miR-1294	CLIP-seq
MIRT1542679	hsa-miR-145	CLIP-seq
MIRT1542680	hsa-miR-1825	CLIP-seq
MIRT2382920	hsa-miR-18a	CLIP-seq
MIRT2382921	hsa-miR-18b	CLIP-seq
MIRT1542681	hsa-miR-1911	CLIP-seq
MIRT1542682	hsa-miR-199a-5p	CLIP-seq
MIRT1542683	hsa-miR-199b-5p	CLIP-seq
MIRT2382922	hsa-miR-205	CLIP-seq
MIRT1542684	hsa-miR-221	CLIP-seq
MIRT1542685	hsa-miR-222	CLIP-seq
MIRT1542686	hsa-miR-3064-3p	CLIP-seq
MIRT1542687	hsa-miR-3119	CLIP-seq
MIRT2382923	hsa-miR-3121-3p	CLIP-seq
MIRT1542689	hsa-miR-3174	CLIP-seq
MIRT1542690	hsa-miR-3182	CLIP-seq
MIRT1542691	hsa-miR-323-3p	CLIP-seq
MIRT2382924	hsa-miR-362-5p	CLIP-seq
MIRT1542692	hsa-miR-3659	CLIP-seq
MIRT2382925	hsa-miR-3664-5p	CLIP-seq
MIRT1542693	hsa-miR-3691-5p	CLIP-seq
MIRT1542694	hsa-miR-377	CLIP-seq
MIRT2382926	hsa-miR-3945	CLIP-seq
MIRT1542697	hsa-miR-412	CLIP-seq
MIRT2382927	hsa-miR-4253	CLIP-seq
MIRT1542698	hsa-miR-4276	CLIP-seq
MIRT1542699	hsa-miR-4316	CLIP-seq
MIRT2382928	hsa-miR-4436a	CLIP-seq
MIRT1542700	hsa-miR-4474-3p	CLIP-seq
MIRT1542702	hsa-miR-4493	CLIP-seq
MIRT1542704	hsa-miR-4635	CLIP-seq
MIRT2382929	hsa-miR-4639-3p	CLIP-seq
MIRT1542706	hsa-miR-4658	CLIP-seq
MIRT1542707	hsa-miR-4659a-3p	CLIP-seq
MIRT1542708	hsa-miR-4659b-3p	CLIP-seq
MIRT1542709	hsa-miR-4715-3p	CLIP-seq
MIRT1542710	hsa-miR-4727-5p	CLIP-seq
MIRT2382930	hsa-miR-4735-3p	CLIP-seq
MIRT1542711	hsa-miR-4751	CLIP-seq
MIRT1542715	hsa-miR-4776-3p	CLIP-seq
MIRT2382931	hsa-miR-500b	CLIP-seq
MIRT2382932	hsa-miR-501-5p	CLIP-seq
MIRT1542717	hsa-miR-548v	CLIP-seq
MIRT1542718	hsa-miR-574-5p	CLIP-seq
MIRT1542719	hsa-miR-603	CLIP-seq
MIRT1542720	hsa-miR-644	CLIP-seq
MIRT1542686	hsa-miR-3064-3p	CLIP-seq
MIRT1542694	hsa-miR-377	CLIP-seq
MIRT1542697	hsa-miR-412	CLIP-seq
MIRT1542702	hsa-miR-4493	CLIP-seq
MIRT1542709	hsa-miR-4715-3p	CLIP-seq
MIRT1542715	hsa-miR-4776-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0003700	Function	DNA-binding transcription factor activity	IDA	25274305
GO:0003700	Function	DNA-binding transcription factor activity	NAS	2023909
GO:0005634	Component	Nucleus	IBA	21873635
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0008270	Function	Zinc ion binding	NAS	2023909
GO:0045892	Process	Negative regulation of transcription, DNA-templated	IDA	25274305
GO:0070895	Process	Negative regulation of transposon integration	IDA	25274305

Other IDs

• MIM: 603975
• HGNC: 13169
• e!Ensembl: ENSG00000184635

Protein

• UniProt ID: P35789
• Protein name: Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34)
• Protein function: Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:252
• PDB: 7Z36
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01352	KRAB	3 → 44	KRAB box	Family
  PF13912	zf-C2H2_6	173 → 198		Domain
  PF00096	zf-C2H2	201 → 223	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	229 → 251	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	257 → 279	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	285 → 307	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	313 → 335	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	341 → 363	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	369 → 391	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	397 → 419	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	425 → 447	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	453 → 475	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	481 → 503	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	509 → 531	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	565 → 587	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	593 → 615	Zinc finger, C2H2 type	Domain

• Sequence:

  MGPLQFRDVAIEFSLEEWHCLDTAQRNLYRNVMLENYSNLVFLGIVVSKPDLIAHLEQGK
  KPLTMKRHEMVANPSVICSHFAQDLWPEQNIKDSFQKVILRRYEKRGHGNLQLIKRCESV
  DECKVHTGGYNGLNQCSTTTQSKVFQCDKYGKVFHKFSNSNRHNIRHTEKKPFKCIECGK
  AFNQFSTLITHKKIHTGEKPYICEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIA
  SSTLSKHEIIHTGKKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTL
  TKHKKIHTGEKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHE
  FIHMGKKHYKCEECGKAFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHT
  GEKPYKCEECGKAFVASSTLSKHEIIHTGKKPYKCEECGKAFNQSSSLTKHKKIHTGEKP
  YKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSTLIKHKKIHTREKPYKCE
  ECGKAFHLSTHLTTHKILHTGEKPYRCRECGKAFNHSATLSSHKKIHSGEKPYECDKCGK
  AFISPSSLSRHEIIHTGEKP

• Sequence length: 620

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Leukemia	Leukemia, Myelocytic, Acute	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601	27903959
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	25944848

Unknown
Disease name	Disease term	dbSNP ID	References
Bipolar disorder	Bipolar Disorder		25944848
Mental depression	Unipolar Depression, Major Depressive Disorder	rs587778876, rs587778877	25944848