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RAB1B (RAB1B, member RAS oncogene family)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
81876
Gene nameGene Name - the full gene name approved by the HGNC.
RAB1B, member RAS oncogene family
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
RAB1B
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
11
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q13.2
SummarySummary of gene provided in NCBI Entrez Gene.
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport b
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT004695 hsa-miR-107 Flow, Immunoblot, Microarray, qRT-PCR 19688090
MIRT020151 hsa-miR-130b-3p Sequencing 20371350
MIRT025973 hsa-miR-148a-3p Sequencing 20371350
MIRT027096 hsa-miR-103a-3p Sequencing 20371350
MIRT031730 hsa-miR-16-5p Sequencing 20371350
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000045 Process Autophagosome assembly IBA 21873635
GO:0000139 Component Golgi membrane TAS
GO:0003924 Function GTPase activity IBA 21873635
GO:0005515 Function Protein binding IPI 15796781, 21378754, 22011575, 25107275, 26824392, 26977884, 28514442, 31046837, 32296183
GO:0005525 Function GTP binding IDA 20937701
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9H0U4
Protein name Ras-related protein Rab-1B (EC 3.6.5.2)
Protein function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:20545908, PubMed:9437002, PubMed:23236136). Rabs cycle between an inactive GDP-bound
PDB 3JZA , 3NKV , 4HLQ , 4I1O , 5O74 , 5SZH , 5SZK , 6SKU , 8ALK
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras
10 171
Ras family
Domain
Sequence
Sequence length 201
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
Reactome
  Legionellosis   Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Myocardial ischemia Myocardial Ischemia 16214533

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