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APOL4 (apolipoprotein L4)

Gene

80832

Apolipoprotein L4

APOL4

APOL-IV, APOLIV

22q12.3

This gene encodes a member of the apolipoprotein L family. The encoded protein may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Alternative splicing result

Show/Hide all(246)

miRTarBase ID	miRNA	Experiments	Reference
MIRT706820	hsa-miR-548n	HITS-CLIP	21572407
MIRT706819	hsa-miR-548az-5p	HITS-CLIP	21572407
MIRT706818	hsa-miR-548t-5p	HITS-CLIP	21572407
MIRT706817	hsa-miR-548l	HITS-CLIP	21572407
MIRT706816	hsa-miR-3129-3p	HITS-CLIP	21572407
MIRT706815	hsa-miR-5583-5p	HITS-CLIP	21572407
MIRT706814	hsa-miR-4496	HITS-CLIP	21572407
MIRT706813	hsa-miR-3163	HITS-CLIP	21572407
MIRT706812	hsa-miR-5092	HITS-CLIP	21572407
MIRT706811	hsa-miR-412-3p	HITS-CLIP	21572407
MIRT706810	hsa-miR-6754-3p	HITS-CLIP	21572407
MIRT706809	hsa-miR-6837-3p	HITS-CLIP	21572407
MIRT706808	hsa-miR-4471	HITS-CLIP	21572407
MIRT706807	hsa-miR-8059	HITS-CLIP	21572407
MIRT706806	hsa-miR-4775	HITS-CLIP	21572407
MIRT706805	hsa-miR-340-5p	HITS-CLIP	21572407
MIRT706804	hsa-miR-513b-5p	HITS-CLIP	21572407
MIRT706803	hsa-miR-3912-5p	HITS-CLIP	21572407
MIRT706802	hsa-miR-4260	HITS-CLIP	21572407
MIRT706801	hsa-miR-5572	HITS-CLIP	21572407
MIRT706820	hsa-miR-548n	HITS-CLIP	21572407
MIRT706819	hsa-miR-548az-5p	HITS-CLIP	21572407
MIRT706818	hsa-miR-548t-5p	HITS-CLIP	21572407
MIRT706817	hsa-miR-548l	HITS-CLIP	21572407
MIRT706816	hsa-miR-3129-3p	HITS-CLIP	21572407
MIRT706815	hsa-miR-5583-5p	HITS-CLIP	21572407
MIRT706814	hsa-miR-4496	HITS-CLIP	21572407
MIRT706813	hsa-miR-3163	HITS-CLIP	21572407
MIRT706812	hsa-miR-5092	HITS-CLIP	21572407
MIRT706811	hsa-miR-412-3p	HITS-CLIP	21572407
MIRT706810	hsa-miR-6754-3p	HITS-CLIP	21572407
MIRT706809	hsa-miR-6837-3p	HITS-CLIP	21572407
MIRT706808	hsa-miR-4471	HITS-CLIP	21572407
MIRT706807	hsa-miR-8059	HITS-CLIP	21572407
MIRT706806	hsa-miR-4775	HITS-CLIP	21572407
MIRT706805	hsa-miR-340-5p	HITS-CLIP	21572407
MIRT706804	hsa-miR-513b-5p	HITS-CLIP	21572407
MIRT706803	hsa-miR-3912-5p	HITS-CLIP	21572407
MIRT706802	hsa-miR-4260	HITS-CLIP	21572407
MIRT706801	hsa-miR-5572	HITS-CLIP	21572407
MIRT790161	hsa-miR-1207-5p	CLIP-seq
MIRT790162	hsa-miR-1226	CLIP-seq
MIRT790163	hsa-miR-1245	CLIP-seq
MIRT790164	hsa-miR-1827	CLIP-seq
MIRT790165	hsa-miR-1909	CLIP-seq
MIRT790166	hsa-miR-2110	CLIP-seq
MIRT790167	hsa-miR-3127-5p	CLIP-seq
MIRT790168	hsa-miR-3150a-3p	CLIP-seq
MIRT790169	hsa-miR-3612	CLIP-seq
MIRT790170	hsa-miR-383	CLIP-seq
MIRT790171	hsa-miR-4271	CLIP-seq
MIRT790172	hsa-miR-4302	CLIP-seq
MIRT790173	hsa-miR-4443	CLIP-seq
MIRT790174	hsa-miR-4457	CLIP-seq
MIRT790175	hsa-miR-4533	CLIP-seq
MIRT790176	hsa-miR-4649-5p	CLIP-seq
MIRT790177	hsa-miR-4725-3p	CLIP-seq
MIRT790178	hsa-miR-4733-3p	CLIP-seq
MIRT790179	hsa-miR-4747-5p	CLIP-seq
MIRT790180	hsa-miR-4763-3p	CLIP-seq
MIRT790181	hsa-miR-4772-5p	CLIP-seq
MIRT790182	hsa-miR-4786-5p	CLIP-seq
MIRT790183	hsa-miR-498	CLIP-seq
MIRT790184	hsa-miR-509-3p	CLIP-seq
MIRT790185	hsa-miR-513b	CLIP-seq
MIRT790186	hsa-miR-548ag	CLIP-seq
MIRT790187	hsa-miR-548ai	CLIP-seq
MIRT790188	hsa-miR-650	CLIP-seq
MIRT790189	hsa-miR-940	CLIP-seq
MIRT790163	hsa-miR-1245	CLIP-seq
MIRT790190	hsa-miR-1283	CLIP-seq
MIRT790166	hsa-miR-2110	CLIP-seq
MIRT790191	hsa-miR-2113	CLIP-seq
MIRT790168	hsa-miR-3150a-3p	CLIP-seq
MIRT790192	hsa-miR-3202	CLIP-seq
MIRT790170	hsa-miR-383	CLIP-seq
MIRT790193	hsa-miR-3912	CLIP-seq
MIRT790194	hsa-miR-3944-5p	CLIP-seq
MIRT790195	hsa-miR-412	CLIP-seq
MIRT790171	hsa-miR-4271	CLIP-seq
MIRT790172	hsa-miR-4302	CLIP-seq
MIRT790196	hsa-miR-432	CLIP-seq
MIRT790174	hsa-miR-4457	CLIP-seq
MIRT790175	hsa-miR-4533	CLIP-seq
MIRT790197	hsa-miR-4643	CLIP-seq
MIRT790198	hsa-miR-4719	CLIP-seq
MIRT790177	hsa-miR-4725-3p	CLIP-seq
MIRT790181	hsa-miR-4772-5p	CLIP-seq
MIRT790184	hsa-miR-509-3p	CLIP-seq
MIRT790185	hsa-miR-513b	CLIP-seq
MIRT790199	hsa-miR-548a-5p	CLIP-seq
MIRT790200	hsa-miR-548ab	CLIP-seq
MIRT790201	hsa-miR-548ak	CLIP-seq
MIRT790202	hsa-miR-548b-5p	CLIP-seq
MIRT790203	hsa-miR-548c-5p	CLIP-seq
MIRT790204	hsa-miR-548d-5p	CLIP-seq
MIRT790205	hsa-miR-548h	CLIP-seq
MIRT790206	hsa-miR-548i	CLIP-seq
MIRT790207	hsa-miR-548j	CLIP-seq
MIRT790208	hsa-miR-548k	CLIP-seq
MIRT790209	hsa-miR-548u	CLIP-seq
MIRT790210	hsa-miR-548w	CLIP-seq
MIRT790211	hsa-miR-548y	CLIP-seq
MIRT790212	hsa-miR-559	CLIP-seq
MIRT790213	hsa-miR-599	CLIP-seq
MIRT1933109	hsa-miR-3161	CLIP-seq
MIRT1933110	hsa-miR-361-5p	CLIP-seq
MIRT1933111	hsa-miR-4433	CLIP-seq
MIRT1933112	hsa-miR-4455	CLIP-seq
MIRT1933113	hsa-miR-4459	CLIP-seq
MIRT790198	hsa-miR-4719	CLIP-seq
MIRT1933114	hsa-miR-4768-3p	CLIP-seq
MIRT1933115	hsa-miR-609	CLIP-seq
MIRT1933116	hsa-miR-616	CLIP-seq
MIRT1933117	hsa-miR-767-5p	CLIP-seq
MIRT790161	hsa-miR-1207-5p	CLIP-seq
MIRT2173252	hsa-miR-1266	CLIP-seq
MIRT790164	hsa-miR-1827	CLIP-seq
MIRT1933109	hsa-miR-3161	CLIP-seq
MIRT790169	hsa-miR-3612	CLIP-seq
MIRT2173253	hsa-miR-3664-3p	CLIP-seq
MIRT790170	hsa-miR-383	CLIP-seq
MIRT790195	hsa-miR-412	CLIP-seq
MIRT2173254	hsa-miR-4270	CLIP-seq
MIRT790172	hsa-miR-4302	CLIP-seq
MIRT2173255	hsa-miR-4326	CLIP-seq
MIRT2173256	hsa-miR-4441	CLIP-seq
MIRT790173	hsa-miR-4443	CLIP-seq
MIRT790174	hsa-miR-4457	CLIP-seq
MIRT2173257	hsa-miR-4518	CLIP-seq
MIRT790176	hsa-miR-4649-5p	CLIP-seq
MIRT2173258	hsa-miR-4753-3p	CLIP-seq
MIRT790180	hsa-miR-4763-3p	CLIP-seq
MIRT790181	hsa-miR-4772-5p	CLIP-seq
MIRT790185	hsa-miR-513b	CLIP-seq
MIRT790186	hsa-miR-548ag	CLIP-seq
MIRT790187	hsa-miR-548ai	CLIP-seq
MIRT790209	hsa-miR-548u	CLIP-seq
MIRT1933116	hsa-miR-616	CLIP-seq
MIRT2173259	hsa-miR-624	CLIP-seq
MIRT790188	hsa-miR-650	CLIP-seq
MIRT1933117	hsa-miR-767-5p	CLIP-seq
MIRT790189	hsa-miR-940	CLIP-seq
MIRT790176	hsa-miR-4649-5p	CLIP-seq
MIRT2443826	hsa-miR-3159	CLIP-seq
MIRT2443827	hsa-miR-4266	CLIP-seq
MIRT790199	hsa-miR-548a-5p	CLIP-seq
MIRT790200	hsa-miR-548ab	CLIP-seq
MIRT790201	hsa-miR-548ak	CLIP-seq
MIRT790202	hsa-miR-548b-5p	CLIP-seq
MIRT790203	hsa-miR-548c-5p	CLIP-seq
MIRT790204	hsa-miR-548d-5p	CLIP-seq
MIRT790205	hsa-miR-548h	CLIP-seq
MIRT790206	hsa-miR-548i	CLIP-seq
MIRT790207	hsa-miR-548j	CLIP-seq
MIRT790208	hsa-miR-548k	CLIP-seq
MIRT790209	hsa-miR-548u	CLIP-seq
MIRT790210	hsa-miR-548w	CLIP-seq
MIRT790211	hsa-miR-548y	CLIP-seq
MIRT790212	hsa-miR-559	CLIP-seq
MIRT2476611	hsa-miR-1208	CLIP-seq
MIRT790163	hsa-miR-1245	CLIP-seq
MIRT2476612	hsa-miR-125a-5p	CLIP-seq
MIRT2476613	hsa-miR-125b	CLIP-seq
MIRT2476614	hsa-miR-1303	CLIP-seq
MIRT2476615	hsa-miR-154	CLIP-seq
MIRT790166	hsa-miR-2110	CLIP-seq
MIRT2476616	hsa-miR-2116	CLIP-seq
MIRT2476617	hsa-miR-302f	CLIP-seq
MIRT790168	hsa-miR-3150a-3p	CLIP-seq
MIRT2476618	hsa-miR-3155	CLIP-seq
MIRT2476619	hsa-miR-3155b	CLIP-seq
MIRT2443826	hsa-miR-3159	CLIP-seq
MIRT2476620	hsa-miR-3664-5p	CLIP-seq
MIRT2476621	hsa-miR-3675-3p	CLIP-seq
MIRT790170	hsa-miR-383	CLIP-seq
MIRT2476622	hsa-miR-3938	CLIP-seq
MIRT790195	hsa-miR-412	CLIP-seq
MIRT2443827	hsa-miR-4266	CLIP-seq
MIRT790171	hsa-miR-4271	CLIP-seq
MIRT2476623	hsa-miR-4284	CLIP-seq
MIRT790172	hsa-miR-4302	CLIP-seq
MIRT2476624	hsa-miR-4319	CLIP-seq
MIRT790174	hsa-miR-4457	CLIP-seq
MIRT2476625	hsa-miR-4477b	CLIP-seq
MIRT2476626	hsa-miR-4522	CLIP-seq
MIRT2476627	hsa-miR-4677-5p	CLIP-seq
MIRT790177	hsa-miR-4725-3p	CLIP-seq
MIRT2476628	hsa-miR-4732-3p	CLIP-seq
MIRT790178	hsa-miR-4733-3p	CLIP-seq
MIRT790181	hsa-miR-4772-5p	CLIP-seq
MIRT2476629	hsa-miR-484	CLIP-seq
MIRT790184	hsa-miR-509-3p	CLIP-seq
MIRT790185	hsa-miR-513b	CLIP-seq
MIRT790199	hsa-miR-548a-5p	CLIP-seq
MIRT790200	hsa-miR-548ab	CLIP-seq
MIRT790201	hsa-miR-548ak	CLIP-seq
MIRT790202	hsa-miR-548b-5p	CLIP-seq
MIRT790203	hsa-miR-548c-5p	CLIP-seq
MIRT790204	hsa-miR-548d-5p	CLIP-seq
MIRT790205	hsa-miR-548h	CLIP-seq
MIRT790206	hsa-miR-548i	CLIP-seq
MIRT790207	hsa-miR-548j	CLIP-seq
MIRT790208	hsa-miR-548k	CLIP-seq
MIRT790209	hsa-miR-548u	CLIP-seq
MIRT790210	hsa-miR-548w	CLIP-seq
MIRT790211	hsa-miR-548y	CLIP-seq
MIRT790212	hsa-miR-559	CLIP-seq
MIRT790213	hsa-miR-599	CLIP-seq
MIRT2476630	hsa-miR-670	CLIP-seq
MIRT2476631	hsa-miR-759	CLIP-seq
MIRT2476611	hsa-miR-1208	CLIP-seq
MIRT2476612	hsa-miR-125a-5p	CLIP-seq
MIRT2476613	hsa-miR-125b	CLIP-seq
MIRT2476615	hsa-miR-154	CLIP-seq
MIRT2476617	hsa-miR-302f	CLIP-seq
MIRT2476618	hsa-miR-3155	CLIP-seq
MIRT2476619	hsa-miR-3155b	CLIP-seq
MIRT2443826	hsa-miR-3159	CLIP-seq
MIRT2476620	hsa-miR-3664-5p	CLIP-seq
MIRT2476621	hsa-miR-3675-3p	CLIP-seq
MIRT2476622	hsa-miR-3938	CLIP-seq
MIRT2443827	hsa-miR-4266	CLIP-seq
MIRT2476623	hsa-miR-4284	CLIP-seq
MIRT2476624	hsa-miR-4319	CLIP-seq
MIRT2476625	hsa-miR-4477b	CLIP-seq
MIRT2476626	hsa-miR-4522	CLIP-seq
MIRT2476628	hsa-miR-4732-3p	CLIP-seq
MIRT790178	hsa-miR-4733-3p	CLIP-seq
MIRT2476629	hsa-miR-484	CLIP-seq
MIRT790199	hsa-miR-548a-5p	CLIP-seq
MIRT790200	hsa-miR-548ab	CLIP-seq
MIRT790201	hsa-miR-548ak	CLIP-seq
MIRT790202	hsa-miR-548b-5p	CLIP-seq
MIRT790203	hsa-miR-548c-5p	CLIP-seq
MIRT790204	hsa-miR-548d-5p	CLIP-seq
MIRT790205	hsa-miR-548h	CLIP-seq
MIRT790206	hsa-miR-548i	CLIP-seq
MIRT790207	hsa-miR-548j	CLIP-seq
MIRT790208	hsa-miR-548k	CLIP-seq
MIRT790209	hsa-miR-548u	CLIP-seq
MIRT790210	hsa-miR-548w	CLIP-seq
MIRT790211	hsa-miR-548y	CLIP-seq
MIRT790212	hsa-miR-559	CLIP-seq
MIRT2476630	hsa-miR-670	CLIP-seq
MIRT2476631	hsa-miR-759	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003674	Function	Molecular_function	ND
GO:0005615	Component	Extracellular space	ISS	22261194
GO:0006629	Process	Lipid metabolic process	NAS	11944986
GO:0006869	Process	Lipid transport	IEA
GO:0008289	Function	Lipid binding	IBA	21873635
GO:0042157	Process	Lipoprotein metabolic process	IEA
GO:0043231	Component	Intracellular membrane-bounded organelle	IDA

MIM	HGNC	e!Ensembl
607254	14867	ENSG00000100336

Protein

UniProt ID

Q9BPW4

Protein name

Apolipoprotein L4 (Apolipoprotein L-IV) (ApoL-IV)

Protein function

May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05461	ApoL	46 → 348	Apolipoprotein L	Family

Sequence

MEGAALLKIFVVCIWVQQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDE
AWKRFVRVAELPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQ
ESIERLRVIANEIEKVHRGCVIANVVSGSTGILSVIGVMLAPFTAGLSLSITAAGVGLGI
ASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILRDITPNVLSFALDFDEAT
KMIANDVHTLRRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVL
VVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKAG

Sequence length

351

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313

Show/Hide Unknown Diseases (2)

Unknown
Disease name	Disease term	dbSNP ID	References
Delusions	Delusions
Hallucinations	Hallucinations

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