GediPNet logo

LPAL2 (lipoprotein(a) like 2, pseudogene)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
80350
Gene nameGene Name - the full gene name approved by the HGNC.
Lipoprotein(a) like 2, pseudogene
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
LPAL2
SynonymsGene synonyms aliases
APOA2, APOAL, APOARGC, apo(a)rg-C
ChromosomeChromosome number
6
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6q25.3
SummarySummary of gene provided in NCBI Entrez Gene.
Apolipoprotein(a) is the distinguishing protein moiety of lipoprotein(a), of which elevated plasma levels are correlated with an increased risk of atherosclerosis. This gene is similar to the lipoprotein, Lp(a) gene, but all transcripts produced by this gene contain a truncated open reading frame and are candidates for nonsense-mediated decay. Consequently, this gene is considered to be a pseudogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016940 hsa-miR-335-5p Microarray 18185580
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0004252 Function Serine-type endopeptidase activity IBA 21873635
GO:0005515 Function Protein binding IPI 25416956, 32814053
GO:0005575 Component Cellular_component ND
GO:0005576 Component Extracellular region IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q16609
Protein name Putative apolipoprotein(a)-like protein 2 (Apo(a)-like protein 2) (Lp(a)-liker protein 2) (Apolipoprotein a-related gene C protein) (Apo(a)rg-C)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00051 Kringle
28 105
Kringle domain
Domain
Sequence
MEHKEVVLLLLLFLKSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQH
SRTPEKYPNDGLISNYCRNPDCSAGPWCYTTDPNVRWEYCNLTRC
SDDEGTVFVPLTVIP
VPSLEDSFIQVA
Sequence length 132
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Coronary artery disease Coronary Artery Disease rs137852988, rs121918313, rs-1, rs121918529, rs121918531, rs137852340, rs405509, rs1555800701, rs1215189537 19198611, 29212778
Coronary heart disease Coronary heart disease rs-1 19198611

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412