GediPNet logo

ZNF614 (zinc finger protein 614)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
80110
Gene nameGene Name - the full gene name approved by the HGNC.
Zinc finger protein 614
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ZNF614
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
19
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19q13.41
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019816 hsa-miR-375 Microarray 20215506
MIRT021968 hsa-miR-128-3p Microarray 17612493
MIRT051733 hsa-let-7c-5p CLASH 23622248
MIRT649222 hsa-miR-3184-3p HITS-CLIP 23824327
MIRT649221 hsa-miR-5196-3p HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IBA 21873635
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0001227 Function DNA-binding transcription repressor activity, RNA polymerase II-specific IBA 21873635
GO:0003674 Function Molecular_function ND
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q8N883
Protein name Zinc finger protein 614
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB
7 48
KRAB box
Family
PF00096 zf-C2H2
287 309
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
315 337
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
343 365
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
371 393
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
399 421
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
427 449
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
483 505
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
511 533
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
539 561
Zinc finger, C2H2 type
Domain
Sequence
MIKTQESLTLEDVAVEFSWEEWQLLDTAQKNLYRDVMVENYNHLVSLGYQTSKPDVLSKL
AHGQEPWTTDAKIQNKNCPGIGKVDSHLQEHSPNQRLLKSVQQCNGQNTLRNIVHLSKTH
FPIVQNHDTFDLYRKNLKSSLSLINQKRRHGINNPVEFIGGEKTLLHGKHERTHTKTRFS
ENAKCIHTKFQVFKHQRTQKIEKPHACIECEQTFLRKSQLIYHENICIQENPGSGQCEKL
SRSVLFTKHLKTNTTDKICIPNEYRKGSTVKSSLITHQQTHTEEKSYMCSECGKGFTMKR
YLIAHQRTH
SGEKPYVCKECGKGFTVKSNLIVHQRTHTGEKPYICSECGKGFTMKRYLVV
HQRTH
TGEKPYMCSECGKGFTVKSNLIVHQRSHTGEKSYICSECGKGFTVKRTLVIHQRT
H
TGEKSYICNECGKGFTTKRTLIIHQRTHTGEKPYECNECGKAFSQKICLIQHERCHTGK
TPFVCTECGKSYSHKYGLITHQRIHTGEKPYECNECGKAFTTKSVLNVHQRTHTGERPYG
CSDCEKAFSHLSNLVKHKKMH
TREMGRISQVENSCNGESQLLPYK
Sequence length 585
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Generic Transcription Pathway
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Asthma Asthma rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283 24280104

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412