Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
800 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Caldesmon 1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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CALD1 |
SynonymsGene synonyms aliases
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CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22, h-CD |
ChromosomeChromosome number
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7 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7q33 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomy |
miRNAmiRNA information provided by mirtarbase database.
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Transcription factors
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Transcription factor |
Regulation |
Reference |
NR3C1 |
Activation |
18772142 |
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q05682 |
Protein name |
Caldesmon (CDM) |
Protein function |
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases th |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF02029 |
Caldesmon |
31 → 299 |
Caldesmon |
Disordered |
PF02029 |
Caldesmon |
296 → 780 |
Caldesmon |
Disordered |
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Sequence |
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Sequence length |
793 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Arthritis |
Juvenile arthritis |
rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470 |
19565504 |
Leukemia |
Leukemia, Myelocytic, Acute |
rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601 |
27903959 |
Rheumatoid arthritis |
Rheumatoid Arthritis |
rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212 |
15292528 |
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Diverticular diseases |
Diverticular Diseases |
|
30177863 |
Juvenile arthritis |
Juvenile psoriatic arthritis |
|
19565504 |
Seronegative polyarthritis |
Polyarthritis, Juvenile, Rheumatoid Factor Negative |
|
19565504 |
Polyarthritis, rheumatoid factor positive |
Polyarthritis, Juvenile, Rheumatoid Factor Positive |
|
19565504 |
Still disease |
Juvenile-Onset Still Disease |
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19565504 |
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