GediPNet logo

QTMAN (queuosine-tRNA mannosyltransferase)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
79712
Gene nameGene Name - the full gene name approved by the HGNC.
Queuosine-tRNA mannosyltransferase
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
QTMAN
SynonymsGene synonyms aliases
GTDC1, Hmat-Xa, mat-Xa
ChromosomeChromosome number
2
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q22.3
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT716978 hsa-miR-101-5p HITS-CLIP 19536157
MIRT716977 hsa-miR-188-5p HITS-CLIP 19536157
MIRT716976 hsa-miR-6866-3p HITS-CLIP 19536157
MIRT716975 hsa-miR-3127-3p HITS-CLIP 19536157
MIRT716974 hsa-miR-6756-3p HITS-CLIP 19536157
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q4AE62
Protein name tRNA-queuosine alpha-mannosyltransferase (QTMAN) (EC 2.4.1.110) (Glycosyltransferase-like domain-containing protein 1) (Mannosyltransferase-like protein Xa) (Mat-Xa)
Protein function Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)) (PubMed:37992713). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl-
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12038 DUF3524
2 167
Domain of unknown function (DUF3524)
Family
PF00534 Glycos_transf_1
279 457
Glycosyl transferases group 1
Family
Sequence
Sequence length 458
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 22037555
Unknown
Disease name Disease term dbSNP ID References
Oral ulcer Oral Ulcer 30837455

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412