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ZFAND5 (zinc finger AN1-type containing 5)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7763
Gene nameGene Name - the full gene name approved by the HGNC.
Zinc finger AN1-type containing 5
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ZFAND5
SynonymsGene synonyms aliases
ZA20D2, ZFAND5A, ZNF216
ChromosomeChromosome number
9
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9q21.13
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT027817 hsa-miR-98-5p Microarray 19088304
MIRT031245 hsa-miR-19b-3p Sequencing 20371350
MIRT031311 hsa-miR-18a-5p Sequencing 20371350
MIRT051626 hsa-let-7e-5p CLASH 23622248
MIRT051626 hsa-let-7e-5p CLASH 23622248
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001701 Process In utero embryonic development IEA
GO:0001944 Process Vasculature development IEA
GO:0003016 Process Respiratory system process IEA
GO:0003674 Function Molecular_function ND
GO:0003677 Function DNA binding IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID O76080
Protein name AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216)
Protein function Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of N
PDB 7QXW
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01754 zf-A20
12 35
A20-like zinc finger
Family
PF01428 zf-AN1
154 191
AN1-like Zinc finger
Family
Sequence
MAQETNQTPGPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPT
SDSASVQRADTSLNNCEGAAGSTSEKSRNVPVAALPVTQQMTEMSISREDKITTPKTEVS
EPVVTQPSPSVSQPSTSQSEEKAPELPKPKKNRCFMCRKKVGLTGFDCRCGNLFCGLHRY
SDKHNCPYDYK
AEAAAKIRKENPVVVAEKIQRI
Sequence length 213
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Esophagus neoplasm Esophageal Neoplasms rs28934578, rs121918714, rs1567556006, rs1575166666 22960999
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17199135
Unknown
Disease name Disease term dbSNP ID References
Prostatic neoplasms Prostatic Neoplasms 17199135

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