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ZNF74 (zinc finger protein 74)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7625
Gene nameGene Name - the full gene name approved by the HGNC.
Zinc finger protein 74
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ZNF74
SynonymsGene synonyms aliases
COS52, ZFP520, ZNF520, hZNF7
ChromosomeChromosome number
22
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q11.21
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT027535 hsa-miR-98-5p Microarray 19088304
MIRT663347 hsa-miR-500b-3p HITS-CLIP 23824327
MIRT663346 hsa-miR-6773-3p HITS-CLIP 23824327
MIRT663345 hsa-miR-215-3p HITS-CLIP 23824327
MIRT663344 hsa-miR-6499-3p HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0003723 Function RNA binding IEA
GO:0005634 Component Nucleus IBA 21873635
GO:0005654 Component Nucleoplasm IDA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q16587
Protein name Zinc finger protein 74 (Zinc finger protein 520) (hZNF7)
Protein function May play a role in RNA metabolism.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB
42 83
KRAB box
Family
PF00096 zf-C2H2
248 270
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
276 298
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
304 326
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
360 382
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
416 438
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
472 494
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
528 550
Zinc finger, C2H2 type
Domain
PF00096 zf-C2H2
556 578
Zinc finger, C2H2 type
Domain
Sequence
MEIPAPEPEKTALSSQDPALSLKENLEDISGWGLPEARSKESVSFKDVAVDFTQEEWGQL
DSPQRALYRDVMLENYQNLLALG
PPLHKPDVISHLERGEEPWSMQREVPRGPCPEWELKA
VPSQQQGICKEEPAQEPIMERPLGGAQAWGRQAGALQRSQAAPWAPAPAMVWDVPVEEFP
LRCPLFAQQRVPEGGPLLDTRKNVQATEGRTKAPARLCAGENASTPSEPEKFPQVRRQRG
AGAGEGEFVCGECGKAFRQSSSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHRRIHTG
EKPFFCGECGKAFSCHSSLNVHQRIHTGERPYKCSACEKAFSCSSLLSMHLRVHTGEKPY
RCGECGKAFNQRTHLTRHHRIH
TGEKPYQCGSCGKAFTCHSSLTVHEKIHSGDKPFKCSD
CEKAFNSRSRLTLHQRTH
TGEKPFKCADCGKGFSCHAYLLVHRRIHSGEKPFKCNECGKA
FSSHAYLIVHRRIH
TGEKPFDCSQCWKAFSCHSSLIVHQRIHTGEKPYKCSECGRAFSQN
HCLIKHQKIH
SGEKSFKCEKCGEMFNWSSHLTEHQRLHSEGKPLAIQFNKHLLSTYYVPG
SLLGAGDAGLRDVDPIDALDVAKLLCVVPPRAGRNFSLGSKPRN
Sequence length 644
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Generic Transcription Pathway
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 11705709

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