Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7433 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Vasoactive intestinal peptide receptor 1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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VIPR1 |
SynonymsGene synonyms aliases
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HVR1, II, PACAP-R-2, PACAP-R2, RDC1, V1RG, VAPC1, VIP-R-1, VIPR, VIRG, VPAC1, VPAC1R, VPCAP1R |
ChromosomeChromosome number
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3 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
3p22.1 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its act |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
P32241 |
Protein name |
Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1 receptor) (VPAC1R) |
Protein function |
G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed:35477937, PubMed:36385145, PubMed:8179610). Binds VIP and both PACAP27 a |
PDB |
1OF2
,
1OGT
,
3B3I
,
3B6S
,
3DTX
,
3HCV
,
5DEF
,
5DEG
,
5IB1
,
5IB2
,
5IB3
,
5IB4
,
5IB5
,
6VN7
,
7ALO
,
8E3Y
,
8E3Z
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF02793 |
HRM |
60 → 125 |
Hormone receptor domain |
Family |
PF00002 |
7tm_2 |
139 → 384 |
7 transmembrane receptor (Secretin family) |
Family |
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Sequence |
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Sequence length |
457 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Liver carcinoma |
Liver carcinoma |
|
28284560 |
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