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VIPR1 (vasoactive intestinal peptide receptor 1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7433
Gene nameGene Name - the full gene name approved by the HGNC.
Vasoactive intestinal peptide receptor 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
VIPR1
SynonymsGene synonyms aliases
HVR1, II, PACAP-R-2, PACAP-R2, RDC1, V1RG, VAPC1, VIP-R-1, VIPR, VIRG, VPAC1, VPAC1R, VPCAP1R
ChromosomeChromosome number
3
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p22.1
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its act
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT609742 hsa-miR-4499 HITS-CLIP 23824327
MIRT609741 hsa-miR-4494 HITS-CLIP 23824327
MIRT609740 hsa-miR-1224-3p HITS-CLIP 23824327
MIRT609739 hsa-miR-532-3p HITS-CLIP 23824327
MIRT609738 hsa-miR-4513 HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004999 Function Vasoactive intestinal polypeptide receptor activity IBA 21873635
GO:0004999 Function Vasoactive intestinal polypeptide receptor activity IDA 8390245
GO:0005515 Function Protein binding IPI 23597562, 32296183
GO:0005886 Component Plasma membrane IBA 21873635
GO:0005886 Component Plasma membrane TAS
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P32241
Protein name Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1 receptor) (VPAC1R)
Protein function G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed:35477937, PubMed:36385145, PubMed:8179610). Binds VIP and both PACAP27 a
PDB 1OF2 , 1OGT , 3B3I , 3B6S , 3DTX , 3HCV , 5DEF , 5DEG , 5IB1 , 5IB2 , 5IB3 , 5IB4 , 5IB5 , 6VN7 , 7ALO , 8E3Y , 8E3Z
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02793 HRM
60 125
Hormone receptor domain
Family
PF00002 7tm_2
139 384
7 transmembrane receptor (Secretin family)
Family
Sequence
Sequence length 457
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
Reactome
  Neuroactive ligand-receptor interaction
Hormone signaling
  G alpha (s) signalling events
Glucagon-type ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Liver carcinoma Liver carcinoma 28284560

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