MRPL49 (mitochondrial ribosomal protein L49)
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Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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740 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Mitochondrial ribosomal protein L49 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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MRPL49 |
SynonymsGene synonyms aliases
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C11orf4, COXPD60, L49mt, MRP-L49, NOF, NOF1, mL49 |
ChromosomeChromosome number
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11 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11q13.1 |
SummarySummary of gene provided in NCBI Entrez Gene.
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
Q13405 |
Protein name |
Large ribosomal subunit protein mL49 (39S ribosomal protein L49, mitochondrial) (L49mt) (MRP-L49) (Neighbor of FAU) (NOF) (Protein NOF1) |
PDB |
3J7Y
,
3J9M
,
5OOL
,
5OOM
,
6I9R
,
6NU2
,
6NU3
,
6VLZ
,
6VMI
,
6ZM5
,
6ZM6
,
6ZS9
,
6ZSA
,
6ZSB
,
6ZSC
,
6ZSD
,
6ZSE
,
6ZSG
,
7A5F
,
7A5G
,
7A5H
,
7A5I
,
7A5J
,
7A5K
,
7L08
,
7L20
,
7O9K
,
7O9M
,
7ODR
,
7ODS
,
7ODT
,
7OF0
,
7OF2
,
7OF3
,
7OF4
,
7OF5
,
7OF6
,
7OF7
,
7OG4
,
7OI6
,
7OI7
,
7OI8
,
7OI9
,
7OIA
,
7OIB
,
7OIC
,
7OID
,
7OIE
,
7PD3
,
7PO4
,
7QH6
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Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF05046 |
Img2 |
82 → 166 |
Mitochondrial large subunit ribosomal protein (Img2) |
Domain |
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Sequence |
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Sequence length |
166 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Melanoma |
melanoma |
rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs1563902635, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340, rs398123152, rs587780668, rs587782083, rs587782206, rs587782792, rs180177042, rs121913381, rs730881675, rs730881674, rs730881677, rs730881673, rs1800586, rs768966657, rs587778189, rs786204195, rs121913321, rs45476696, rs864622636, rs864622263, rs869025340, rs876660436, rs876658534, rs876658556, rs878853647, rs878853644, rs878853650, rs886041162, rs121913389, rs1057519852, rs121913384, rs121913387, rs1060501266, rs1060501263, rs1060501262, rs749714198, rs1060501265, rs559848002, rs1064794292, rs1131691187, rs1131691186, rs199907548, rs1554654052, rs1554656411, rs1554656624, rs1554653915, rs1554653956, rs1554656253, rs1554654224, rs754806883, rs1057520039, rs1563889584, rs1563889685, rs1287464120, rs1563888944, rs1563892715, rs1563889847, rs141798398, rs1587332338, rs1587340291, rs11552823, rs561034503, rs138677674, rs1819962958, rs1820531050 |
22535842 |
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