UBE2L3 (ubiquitin conjugating enzyme E2 L3)

Gene

• Entrez ID: 7332
• Gene name: Ubiquitin conjugating enzyme E2 L3
• Gene symbol: UBE2L3
• Synonyms: E2-F1, L-UBC, UBCH7, UbcM4
• Chromosome: 22
• Chromosome location: 22q11.21
• Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjuga

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT023267	hsa-miR-122-5p	Microarray	17612493
MIRT048772	hsa-miR-93-5p	CLASH	23622248
MIRT038073	hsa-miR-423-5p	CLASH	23622248
MIRT054872	hsa-miR-125a-5p	qRT-PCR	24675842
MIRT1468205	hsa-miR-10a	CLIP-seq
MIRT1468206	hsa-miR-10b	CLIP-seq
MIRT1468207	hsa-miR-1178	CLIP-seq
MIRT1468208	hsa-miR-1183	CLIP-seq
MIRT1468209	hsa-miR-1207-3p	CLIP-seq
MIRT1468210	hsa-miR-1245b-3p	CLIP-seq
MIRT1468211	hsa-miR-127-5p	CLIP-seq
MIRT1468212	hsa-miR-1283	CLIP-seq
MIRT1468213	hsa-miR-1287	CLIP-seq
MIRT1468214	hsa-miR-1297	CLIP-seq
MIRT1468215	hsa-miR-1323	CLIP-seq
MIRT1468216	hsa-miR-1587	CLIP-seq
MIRT1468217	hsa-miR-185	CLIP-seq
MIRT1468218	hsa-miR-2276	CLIP-seq
MIRT1468219	hsa-miR-2682	CLIP-seq
MIRT1468220	hsa-miR-26a	CLIP-seq
MIRT1468221	hsa-miR-26b	CLIP-seq
MIRT1468222	hsa-miR-3064-3p	CLIP-seq
MIRT1468223	hsa-miR-3064-5p	CLIP-seq
MIRT1468224	hsa-miR-3125	CLIP-seq
MIRT1468225	hsa-miR-3135b	CLIP-seq
MIRT1468226	hsa-miR-3163	CLIP-seq
MIRT1468227	hsa-miR-3177-3p	CLIP-seq
MIRT1468228	hsa-miR-3194-3p	CLIP-seq
MIRT1468229	hsa-miR-338-5p	CLIP-seq
MIRT1468230	hsa-miR-342-3p	CLIP-seq
MIRT1468231	hsa-miR-3605-3p	CLIP-seq
MIRT1468232	hsa-miR-3613-3p	CLIP-seq
MIRT1468233	hsa-miR-3616-5p	CLIP-seq
MIRT1468234	hsa-miR-3647-5p	CLIP-seq
MIRT1468235	hsa-miR-3692	CLIP-seq
MIRT1468236	hsa-miR-370	CLIP-seq
MIRT1468237	hsa-miR-3714	CLIP-seq
MIRT1468238	hsa-miR-377	CLIP-seq
MIRT1468239	hsa-miR-378g	CLIP-seq
MIRT1468240	hsa-miR-3916	CLIP-seq
MIRT1468241	hsa-miR-3937	CLIP-seq
MIRT1468242	hsa-miR-409-5p	CLIP-seq
MIRT1468243	hsa-miR-423-3p	CLIP-seq
MIRT1468244	hsa-miR-4306	CLIP-seq
MIRT1468245	hsa-miR-4427	CLIP-seq
MIRT1468246	hsa-miR-4465	CLIP-seq
MIRT1468247	hsa-miR-4492	CLIP-seq
MIRT1468248	hsa-miR-4493	CLIP-seq
MIRT1468249	hsa-miR-4498	CLIP-seq
MIRT1468250	hsa-miR-449c	CLIP-seq
MIRT1468251	hsa-miR-4505	CLIP-seq
MIRT1468252	hsa-miR-4519	CLIP-seq
MIRT1468253	hsa-miR-4522	CLIP-seq
MIRT1468254	hsa-miR-4530	CLIP-seq
MIRT1468255	hsa-miR-4532	CLIP-seq
MIRT1468256	hsa-miR-4633-3p	CLIP-seq
MIRT1468257	hsa-miR-4644	CLIP-seq
MIRT1468258	hsa-miR-4653-3p	CLIP-seq
MIRT1468259	hsa-miR-4656	CLIP-seq
MIRT1468260	hsa-miR-4671-5p	CLIP-seq
MIRT1468261	hsa-miR-4675	CLIP-seq
MIRT1468262	hsa-miR-4677-3p	CLIP-seq
MIRT1468263	hsa-miR-4680-3p	CLIP-seq
MIRT1468264	hsa-miR-4706	CLIP-seq
MIRT1468265	hsa-miR-4741	CLIP-seq
MIRT1468266	hsa-miR-4749-5p	CLIP-seq
MIRT1468267	hsa-miR-4755-3p	CLIP-seq
MIRT1468268	hsa-miR-4765	CLIP-seq
MIRT1468269	hsa-miR-4772-3p	CLIP-seq
MIRT1468270	hsa-miR-4773	CLIP-seq
MIRT1468271	hsa-miR-4797-5p	CLIP-seq
MIRT1468272	hsa-miR-488	CLIP-seq
MIRT1468273	hsa-miR-500a	CLIP-seq
MIRT1468274	hsa-miR-501-5p	CLIP-seq
MIRT1468275	hsa-miR-5095	CLIP-seq
MIRT1468276	hsa-miR-513a-3p	CLIP-seq
MIRT1468277	hsa-miR-516b	CLIP-seq
MIRT1468278	hsa-miR-518a-5p	CLIP-seq
MIRT1468279	hsa-miR-527	CLIP-seq
MIRT1468280	hsa-miR-542-3p	CLIP-seq
MIRT1468281	hsa-miR-548an	CLIP-seq
MIRT1468282	hsa-miR-548o	CLIP-seq
MIRT1468283	hsa-miR-552	CLIP-seq
MIRT1468284	hsa-miR-556-3p	CLIP-seq
MIRT1468285	hsa-miR-564	CLIP-seq
MIRT1468286	hsa-miR-573	CLIP-seq
MIRT1468287	hsa-miR-593	CLIP-seq
MIRT1468288	hsa-miR-604	CLIP-seq
MIRT1468289	hsa-miR-634	CLIP-seq
MIRT1468290	hsa-miR-638	CLIP-seq
MIRT1468291	hsa-miR-647	CLIP-seq
MIRT1468292	hsa-miR-744	CLIP-seq
MIRT1468293	hsa-miR-762	CLIP-seq
MIRT1468294	hsa-miR-765	CLIP-seq
MIRT1468295	hsa-miR-767-3p	CLIP-seq
MIRT1468296	hsa-miR-802	CLIP-seq
MIRT1468297	hsa-miR-922	CLIP-seq
MIRT1468211	hsa-miR-127-5p	CLIP-seq
MIRT1468212	hsa-miR-1283	CLIP-seq
MIRT1468216	hsa-miR-1587	CLIP-seq
MIRT2140682	hsa-miR-2114	CLIP-seq
MIRT1468222	hsa-miR-3064-3p	CLIP-seq
MIRT1468223	hsa-miR-3064-5p	CLIP-seq
MIRT1468224	hsa-miR-3125	CLIP-seq
MIRT2140683	hsa-miR-329	CLIP-seq
MIRT2140684	hsa-miR-362-3p	CLIP-seq
MIRT1468235	hsa-miR-3692	CLIP-seq
MIRT1468236	hsa-miR-370	CLIP-seq
MIRT1468238	hsa-miR-377	CLIP-seq
MIRT1468239	hsa-miR-378g	CLIP-seq
MIRT1468240	hsa-miR-3916	CLIP-seq
MIRT1468241	hsa-miR-3937	CLIP-seq
MIRT2140685	hsa-miR-4282	CLIP-seq
MIRT1468245	hsa-miR-4427	CLIP-seq
MIRT2140686	hsa-miR-4468	CLIP-seq
MIRT1468247	hsa-miR-4492	CLIP-seq
MIRT1468249	hsa-miR-4498	CLIP-seq
MIRT1468251	hsa-miR-4505	CLIP-seq
MIRT2140687	hsa-miR-4514	CLIP-seq
MIRT2140688	hsa-miR-4520a-3p	CLIP-seq
MIRT2140689	hsa-miR-4520b-3p	CLIP-seq
MIRT1468255	hsa-miR-4532	CLIP-seq
MIRT1468259	hsa-miR-4656	CLIP-seq
MIRT2140690	hsa-miR-466	CLIP-seq
MIRT1468260	hsa-miR-4671-5p	CLIP-seq
MIRT2140691	hsa-miR-4672	CLIP-seq
MIRT1468261	hsa-miR-4675	CLIP-seq
MIRT1468263	hsa-miR-4680-3p	CLIP-seq
MIRT2140692	hsa-miR-4687-3p	CLIP-seq
MIRT2140693	hsa-miR-4692	CLIP-seq
MIRT1468264	hsa-miR-4706	CLIP-seq
MIRT2140694	hsa-miR-4731-3p	CLIP-seq
MIRT1468265	hsa-miR-4741	CLIP-seq
MIRT1468266	hsa-miR-4749-5p	CLIP-seq
MIRT1468267	hsa-miR-4755-3p	CLIP-seq
MIRT1468271	hsa-miR-4797-5p	CLIP-seq
MIRT2140695	hsa-miR-4801	CLIP-seq
MIRT1468285	hsa-miR-564	CLIP-seq
MIRT2140696	hsa-miR-595	CLIP-seq
MIRT1468292	hsa-miR-744	CLIP-seq
MIRT1468293	hsa-miR-762	CLIP-seq
MIRT2361680	hsa-miR-103a	CLIP-seq
MIRT2361681	hsa-miR-107	CLIP-seq
MIRT1468210	hsa-miR-1245b-3p	CLIP-seq
MIRT1468211	hsa-miR-127-5p	CLIP-seq
MIRT2361682	hsa-miR-128	CLIP-seq
MIRT1468212	hsa-miR-1283	CLIP-seq
MIRT2361683	hsa-miR-140-3p	CLIP-seq
MIRT2140682	hsa-miR-2114	CLIP-seq
MIRT1468222	hsa-miR-3064-3p	CLIP-seq
MIRT1468225	hsa-miR-3135b	CLIP-seq
MIRT1468227	hsa-miR-3177-3p	CLIP-seq
MIRT1468231	hsa-miR-3605-3p	CLIP-seq
MIRT2361684	hsa-miR-3612	CLIP-seq
MIRT1468233	hsa-miR-3616-5p	CLIP-seq
MIRT1468234	hsa-miR-3647-5p	CLIP-seq
MIRT2361685	hsa-miR-3649	CLIP-seq
MIRT2361686	hsa-miR-3664-3p	CLIP-seq
MIRT1468235	hsa-miR-3692	CLIP-seq
MIRT1468236	hsa-miR-370	CLIP-seq
MIRT1468238	hsa-miR-377	CLIP-seq
MIRT1468241	hsa-miR-3937	CLIP-seq
MIRT1468243	hsa-miR-423-3p	CLIP-seq
MIRT1468245	hsa-miR-4427	CLIP-seq
MIRT2361687	hsa-miR-4433	CLIP-seq
MIRT2361688	hsa-miR-4443	CLIP-seq
MIRT2361689	hsa-miR-4459	CLIP-seq
MIRT2361690	hsa-miR-4508	CLIP-seq
MIRT1468252	hsa-miR-4519	CLIP-seq
MIRT2361691	hsa-miR-4639-5p	CLIP-seq
MIRT1468263	hsa-miR-4680-3p	CLIP-seq
MIRT1468264	hsa-miR-4706	CLIP-seq
MIRT2361692	hsa-miR-4733-3p	CLIP-seq
MIRT1468266	hsa-miR-4749-5p	CLIP-seq
MIRT1468267	hsa-miR-4755-3p	CLIP-seq
MIRT2361693	hsa-miR-4768-3p	CLIP-seq
MIRT1468271	hsa-miR-4797-5p	CLIP-seq
MIRT1468280	hsa-miR-542-3p	CLIP-seq
MIRT1468285	hsa-miR-564	CLIP-seq
MIRT1468286	hsa-miR-573	CLIP-seq
MIRT1468290	hsa-miR-638	CLIP-seq
MIRT2361694	hsa-miR-650	CLIP-seq
MIRT1468292	hsa-miR-744	CLIP-seq
MIRT1468296	hsa-miR-802	CLIP-seq
MIRT1468297	hsa-miR-922	CLIP-seq
MIRT1468267	hsa-miR-4755-3p	CLIP-seq
MIRT2396587	hsa-miR-4779	CLIP-seq
MIRT1468285	hsa-miR-564	CLIP-seq
MIRT1468294	hsa-miR-765	CLIP-seq
MIRT2466294	hsa-miR-1321	CLIP-seq
MIRT2466295	hsa-miR-2467-3p	CLIP-seq
MIRT2466296	hsa-miR-3150a-3p	CLIP-seq
MIRT2466297	hsa-miR-3162-5p	CLIP-seq
MIRT2466298	hsa-miR-3175	CLIP-seq
MIRT2140686	hsa-miR-4468	CLIP-seq
MIRT2466299	hsa-miR-4533	CLIP-seq
MIRT2466300	hsa-miR-4739	CLIP-seq
MIRT2466301	hsa-miR-4747-5p	CLIP-seq
MIRT2466302	hsa-miR-4756-5p	CLIP-seq
MIRT2466303	hsa-miR-939	CLIP-seq
MIRT1468207	hsa-miR-1178	CLIP-seq
MIRT2655379	hsa-miR-1204	CLIP-seq
MIRT2655380	hsa-miR-1205	CLIP-seq
MIRT1468209	hsa-miR-1207-3p	CLIP-seq
MIRT1468210	hsa-miR-1245b-3p	CLIP-seq
MIRT2655381	hsa-miR-1265	CLIP-seq
MIRT1468212	hsa-miR-1283	CLIP-seq
MIRT1468213	hsa-miR-1287	CLIP-seq
MIRT2655382	hsa-miR-1289	CLIP-seq
MIRT2655383	hsa-miR-1299	CLIP-seq
MIRT2655384	hsa-miR-1302	CLIP-seq
MIRT2655385	hsa-miR-1306	CLIP-seq
MIRT2655386	hsa-miR-149	CLIP-seq
MIRT1468216	hsa-miR-1587	CLIP-seq
MIRT1468217	hsa-miR-185	CLIP-seq
MIRT2655387	hsa-miR-1909	CLIP-seq
MIRT2655388	hsa-miR-214	CLIP-seq
MIRT2655389	hsa-miR-224	CLIP-seq
MIRT1468218	hsa-miR-2276	CLIP-seq
MIRT1468222	hsa-miR-3064-3p	CLIP-seq
MIRT1468223	hsa-miR-3064-5p	CLIP-seq
MIRT1468224	hsa-miR-3125	CLIP-seq
MIRT2655390	hsa-miR-3127-5p	CLIP-seq
MIRT1468225	hsa-miR-3135b	CLIP-seq
MIRT2655391	hsa-miR-3137	CLIP-seq
MIRT2655392	hsa-miR-3150b-3p	CLIP-seq
MIRT2655393	hsa-miR-3152-5p	CLIP-seq
MIRT2655394	hsa-miR-3156-5p	CLIP-seq
MIRT2655395	hsa-miR-3158-3p	CLIP-seq
MIRT2655396	hsa-miR-3169	CLIP-seq
MIRT2655397	hsa-miR-3170	CLIP-seq
MIRT1468227	hsa-miR-3177-3p	CLIP-seq
MIRT2655398	hsa-miR-3189-3p	CLIP-seq
MIRT2655399	hsa-miR-3198	CLIP-seq
MIRT2655400	hsa-miR-340	CLIP-seq
MIRT1468230	hsa-miR-342-3p	CLIP-seq
MIRT2655401	hsa-miR-342-5p	CLIP-seq
MIRT1468231	hsa-miR-3605-3p	CLIP-seq
MIRT2655402	hsa-miR-3619-5p	CLIP-seq
MIRT2361685	hsa-miR-3649	CLIP-seq
MIRT2361686	hsa-miR-3664-3p	CLIP-seq
MIRT2655403	hsa-miR-3683	CLIP-seq
MIRT1468235	hsa-miR-3692	CLIP-seq
MIRT1468236	hsa-miR-370	CLIP-seq
MIRT1468238	hsa-miR-377	CLIP-seq
MIRT1468239	hsa-miR-378g	CLIP-seq
MIRT2655404	hsa-miR-3908	CLIP-seq
MIRT2655405	hsa-miR-3913-3p	CLIP-seq
MIRT1468240	hsa-miR-3916	CLIP-seq
MIRT2655406	hsa-miR-3918	CLIP-seq
MIRT2655407	hsa-miR-3919	CLIP-seq
MIRT1468241	hsa-miR-3937	CLIP-seq
MIRT2655408	hsa-miR-4270	CLIP-seq
MIRT2140685	hsa-miR-4282	CLIP-seq
MIRT2655409	hsa-miR-4291	CLIP-seq
MIRT2655410	hsa-miR-4294	CLIP-seq
MIRT2655411	hsa-miR-4298	CLIP-seq
MIRT1468244	hsa-miR-4306	CLIP-seq
MIRT2655412	hsa-miR-4309	CLIP-seq
MIRT2655413	hsa-miR-4318	CLIP-seq
MIRT1468245	hsa-miR-4427	CLIP-seq
MIRT2361687	hsa-miR-4433	CLIP-seq
MIRT2655414	hsa-miR-4434	CLIP-seq
MIRT2655415	hsa-miR-4441	CLIP-seq
MIRT2655416	hsa-miR-4455	CLIP-seq
MIRT2361689	hsa-miR-4459	CLIP-seq
MIRT2655417	hsa-miR-4474-3p	CLIP-seq
MIRT1468247	hsa-miR-4492	CLIP-seq
MIRT1468249	hsa-miR-4498	CLIP-seq
MIRT1468251	hsa-miR-4505	CLIP-seq
MIRT2655418	hsa-miR-4511	CLIP-seq
MIRT2140687	hsa-miR-4514	CLIP-seq
MIRT2655419	hsa-miR-4515	CLIP-seq
MIRT2655420	hsa-miR-4516	CLIP-seq
MIRT1468253	hsa-miR-4522	CLIP-seq
MIRT1468254	hsa-miR-4530	CLIP-seq
MIRT1468255	hsa-miR-4532	CLIP-seq
MIRT2655421	hsa-miR-4536	CLIP-seq
MIRT1468257	hsa-miR-4644	CLIP-seq
MIRT2655422	hsa-miR-4651	CLIP-seq
MIRT1468258	hsa-miR-4653-3p	CLIP-seq
MIRT1468259	hsa-miR-4656	CLIP-seq
MIRT2655423	hsa-miR-4664-5p	CLIP-seq
MIRT1468260	hsa-miR-4671-5p	CLIP-seq
MIRT1468261	hsa-miR-4675	CLIP-seq
MIRT1468262	hsa-miR-4677-3p	CLIP-seq
MIRT1468263	hsa-miR-4680-3p	CLIP-seq
MIRT2140692	hsa-miR-4687-3p	CLIP-seq
MIRT2655424	hsa-miR-4689	CLIP-seq
MIRT2140693	hsa-miR-4692	CLIP-seq
MIRT2655425	hsa-miR-4693-5p	CLIP-seq
MIRT2655426	hsa-miR-4695-3p	CLIP-seq
MIRT1468264	hsa-miR-4706	CLIP-seq
MIRT2655427	hsa-miR-4708-3p	CLIP-seq
MIRT2140694	hsa-miR-4731-3p	CLIP-seq
MIRT1468265	hsa-miR-4741	CLIP-seq
MIRT2655428	hsa-miR-4747-3p	CLIP-seq
MIRT1468266	hsa-miR-4749-5p	CLIP-seq
MIRT1468267	hsa-miR-4755-3p	CLIP-seq
MIRT2655429	hsa-miR-4763-5p	CLIP-seq
MIRT2361693	hsa-miR-4768-3p	CLIP-seq
MIRT1468269	hsa-miR-4772-3p	CLIP-seq
MIRT2655430	hsa-miR-4774-3p	CLIP-seq
MIRT2396587	hsa-miR-4779	CLIP-seq
MIRT2655431	hsa-miR-4782-5p	CLIP-seq
MIRT2655432	hsa-miR-4784	CLIP-seq
MIRT2655433	hsa-miR-4794	CLIP-seq
MIRT2655434	hsa-miR-4795-5p	CLIP-seq
MIRT1468271	hsa-miR-4797-5p	CLIP-seq
MIRT2140695	hsa-miR-4801	CLIP-seq
MIRT2655435	hsa-miR-489	CLIP-seq
MIRT2655436	hsa-miR-490-3p	CLIP-seq
MIRT2655437	hsa-miR-502-5p	CLIP-seq
MIRT1468276	hsa-miR-513a-3p	CLIP-seq
MIRT2655438	hsa-miR-513c	CLIP-seq
MIRT2655439	hsa-miR-514b-5p	CLIP-seq
MIRT2655440	hsa-miR-515-5p	CLIP-seq
MIRT2655441	hsa-miR-516a-3p	CLIP-seq
MIRT1468277	hsa-miR-516b	CLIP-seq
MIRT1468278	hsa-miR-518a-5p	CLIP-seq
MIRT2655442	hsa-miR-520a-5p	CLIP-seq
MIRT2655443	hsa-miR-525-5p	CLIP-seq
MIRT1468279	hsa-miR-527	CLIP-seq
MIRT1468280	hsa-miR-542-3p	CLIP-seq
MIRT2655444	hsa-miR-548g	CLIP-seq
MIRT2655445	hsa-miR-556-5p	CLIP-seq
MIRT2655446	hsa-miR-561	CLIP-seq
MIRT1468285	hsa-miR-564	CLIP-seq
MIRT1468287	hsa-miR-593	CLIP-seq
MIRT1468288	hsa-miR-604	CLIP-seq
MIRT2655447	hsa-miR-607	CLIP-seq
MIRT2655448	hsa-miR-608	CLIP-seq
MIRT2655449	hsa-miR-610	CLIP-seq
MIRT1468289	hsa-miR-634	CLIP-seq
MIRT2655450	hsa-miR-642b	CLIP-seq
MIRT2655451	hsa-miR-644	CLIP-seq
MIRT1468291	hsa-miR-647	CLIP-seq
MIRT1468292	hsa-miR-744	CLIP-seq
MIRT2655452	hsa-miR-761	CLIP-seq
MIRT1468293	hsa-miR-762	CLIP-seq
MIRT1468294	hsa-miR-765	CLIP-seq
MIRT1468295	hsa-miR-767-3p	CLIP-seq
MIRT2655453	hsa-miR-892a	CLIP-seq
MIRT1468297	hsa-miR-922	CLIP-seq
MIRT2655454	hsa-miR-940	CLIP-seq
MIRT2655455	hsa-miR-942	CLIP-seq
MIRT1468207	hsa-miR-1178	CLIP-seq
MIRT2655379	hsa-miR-1204	CLIP-seq
MIRT2655380	hsa-miR-1205	CLIP-seq
MIRT1468209	hsa-miR-1207-3p	CLIP-seq
MIRT2694648	hsa-miR-1246	CLIP-seq
MIRT2655381	hsa-miR-1265	CLIP-seq
MIRT1468212	hsa-miR-1283	CLIP-seq
MIRT1468213	hsa-miR-1287	CLIP-seq
MIRT2655383	hsa-miR-1299	CLIP-seq
MIRT2655384	hsa-miR-1302	CLIP-seq
MIRT2655385	hsa-miR-1306	CLIP-seq
MIRT2655386	hsa-miR-149	CLIP-seq
MIRT1468216	hsa-miR-1587	CLIP-seq
MIRT2655387	hsa-miR-1909	CLIP-seq
MIRT2655388	hsa-miR-214	CLIP-seq
MIRT2655389	hsa-miR-224	CLIP-seq
MIRT1468218	hsa-miR-2276	CLIP-seq
MIRT1468222	hsa-miR-3064-3p	CLIP-seq
MIRT1468223	hsa-miR-3064-5p	CLIP-seq
MIRT1468224	hsa-miR-3125	CLIP-seq
MIRT2655390	hsa-miR-3127-5p	CLIP-seq
MIRT1468225	hsa-miR-3135b	CLIP-seq
MIRT2655391	hsa-miR-3137	CLIP-seq
MIRT2655392	hsa-miR-3150b-3p	CLIP-seq
MIRT2655393	hsa-miR-3152-5p	CLIP-seq
MIRT2655394	hsa-miR-3156-5p	CLIP-seq
MIRT2655395	hsa-miR-3158-3p	CLIP-seq
MIRT2655396	hsa-miR-3169	CLIP-seq
MIRT2655397	hsa-miR-3170	CLIP-seq
MIRT1468227	hsa-miR-3177-3p	CLIP-seq
MIRT2655398	hsa-miR-3189-3p	CLIP-seq
MIRT1468228	hsa-miR-3194-3p	CLIP-seq
MIRT2655400	hsa-miR-340	CLIP-seq
MIRT1468230	hsa-miR-342-3p	CLIP-seq
MIRT2655401	hsa-miR-342-5p	CLIP-seq
MIRT2655402	hsa-miR-3619-5p	CLIP-seq
MIRT2361685	hsa-miR-3649	CLIP-seq
MIRT2655403	hsa-miR-3683	CLIP-seq
MIRT1468235	hsa-miR-3692	CLIP-seq
MIRT1468236	hsa-miR-370	CLIP-seq
MIRT1468238	hsa-miR-377	CLIP-seq
MIRT1468239	hsa-miR-378g	CLIP-seq
MIRT2655404	hsa-miR-3908	CLIP-seq
MIRT2655405	hsa-miR-3913-3p	CLIP-seq
MIRT1468240	hsa-miR-3916	CLIP-seq
MIRT2655406	hsa-miR-3918	CLIP-seq
MIRT2655407	hsa-miR-3919	CLIP-seq
MIRT1468241	hsa-miR-3937	CLIP-seq
MIRT2655408	hsa-miR-4270	CLIP-seq
MIRT2140685	hsa-miR-4282	CLIP-seq
MIRT2655409	hsa-miR-4291	CLIP-seq
MIRT2655411	hsa-miR-4298	CLIP-seq
MIRT2655413	hsa-miR-4318	CLIP-seq
MIRT2694649	hsa-miR-4320	CLIP-seq
MIRT1468245	hsa-miR-4427	CLIP-seq
MIRT2655414	hsa-miR-4434	CLIP-seq
MIRT2655415	hsa-miR-4441	CLIP-seq
MIRT2655416	hsa-miR-4455	CLIP-seq
MIRT2655417	hsa-miR-4474-3p	CLIP-seq
MIRT1468247	hsa-miR-4492	CLIP-seq
MIRT1468249	hsa-miR-4498	CLIP-seq
MIRT1468251	hsa-miR-4505	CLIP-seq
MIRT2655418	hsa-miR-4511	CLIP-seq
MIRT2140687	hsa-miR-4514	CLIP-seq
MIRT2655419	hsa-miR-4515	CLIP-seq
MIRT2655420	hsa-miR-4516	CLIP-seq
MIRT1468253	hsa-miR-4522	CLIP-seq
MIRT1468254	hsa-miR-4530	CLIP-seq
MIRT1468255	hsa-miR-4532	CLIP-seq
MIRT2655421	hsa-miR-4536	CLIP-seq
MIRT2655422	hsa-miR-4651	CLIP-seq
MIRT1468258	hsa-miR-4653-3p	CLIP-seq
MIRT1468259	hsa-miR-4656	CLIP-seq
MIRT2655423	hsa-miR-4664-5p	CLIP-seq
MIRT1468260	hsa-miR-4671-5p	CLIP-seq
MIRT1468261	hsa-miR-4675	CLIP-seq
MIRT1468262	hsa-miR-4677-3p	CLIP-seq
MIRT1468263	hsa-miR-4680-3p	CLIP-seq
MIRT2140692	hsa-miR-4687-3p	CLIP-seq
MIRT2655424	hsa-miR-4689	CLIP-seq
MIRT2140693	hsa-miR-4692	CLIP-seq
MIRT2655425	hsa-miR-4693-5p	CLIP-seq
MIRT2655426	hsa-miR-4695-3p	CLIP-seq
MIRT1468264	hsa-miR-4706	CLIP-seq
MIRT2655427	hsa-miR-4708-3p	CLIP-seq
MIRT2140694	hsa-miR-4731-3p	CLIP-seq
MIRT1468265	hsa-miR-4741	CLIP-seq
MIRT2655428	hsa-miR-4747-3p	CLIP-seq
MIRT1468266	hsa-miR-4749-5p	CLIP-seq
MIRT1468267	hsa-miR-4755-3p	CLIP-seq
MIRT2655429	hsa-miR-4763-5p	CLIP-seq
MIRT1468269	hsa-miR-4772-3p	CLIP-seq
MIRT2655430	hsa-miR-4774-3p	CLIP-seq
MIRT2396587	hsa-miR-4779	CLIP-seq
MIRT2655431	hsa-miR-4782-5p	CLIP-seq
MIRT2655432	hsa-miR-4784	CLIP-seq
MIRT2655433	hsa-miR-4794	CLIP-seq
MIRT1468271	hsa-miR-4797-5p	CLIP-seq
MIRT2140695	hsa-miR-4801	CLIP-seq
MIRT2694650	hsa-miR-4802-3p	CLIP-seq
MIRT2655435	hsa-miR-489	CLIP-seq
MIRT2655436	hsa-miR-490-3p	CLIP-seq
MIRT2694651	hsa-miR-490-5p	CLIP-seq
MIRT2655437	hsa-miR-502-5p	CLIP-seq
MIRT1468276	hsa-miR-513a-3p	CLIP-seq
MIRT2655438	hsa-miR-513c	CLIP-seq
MIRT2655439	hsa-miR-514b-5p	CLIP-seq
MIRT2655440	hsa-miR-515-5p	CLIP-seq
MIRT2655441	hsa-miR-516a-3p	CLIP-seq
MIRT1468277	hsa-miR-516b	CLIP-seq
MIRT1468278	hsa-miR-518a-5p	CLIP-seq
MIRT2655442	hsa-miR-520a-5p	CLIP-seq
MIRT2694652	hsa-miR-520d-5p	CLIP-seq
MIRT2694653	hsa-miR-522	CLIP-seq
MIRT2694654	hsa-miR-524-5p	CLIP-seq
MIRT2655443	hsa-miR-525-5p	CLIP-seq
MIRT1468279	hsa-miR-527	CLIP-seq
MIRT2655444	hsa-miR-548g	CLIP-seq
MIRT2655446	hsa-miR-561	CLIP-seq
MIRT1468285	hsa-miR-564	CLIP-seq
MIRT1468287	hsa-miR-593	CLIP-seq
MIRT1468288	hsa-miR-604	CLIP-seq
MIRT2655448	hsa-miR-608	CLIP-seq
MIRT1468289	hsa-miR-634	CLIP-seq
MIRT2655450	hsa-miR-642b	CLIP-seq
MIRT2655451	hsa-miR-644	CLIP-seq
MIRT1468291	hsa-miR-647	CLIP-seq
MIRT1468292	hsa-miR-744	CLIP-seq
MIRT2655452	hsa-miR-761	CLIP-seq
MIRT1468293	hsa-miR-762	CLIP-seq
MIRT1468294	hsa-miR-765	CLIP-seq
MIRT1468295	hsa-miR-767-3p	CLIP-seq
MIRT2655453	hsa-miR-892a	CLIP-seq
MIRT1468297	hsa-miR-922	CLIP-seq
MIRT2655454	hsa-miR-940	CLIP-seq
MIRT2655455	hsa-miR-942	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000151	Component	Ubiquitin ligase complex	IBA	21873635
GO:0000151	Component	Ubiquitin ligase complex	TAS	8563171
GO:0000209	Process	Protein polyubiquitination	IBA	21873635
GO:0000209	Process	Protein polyubiquitination	IDA	10888878, 14765125
GO:0003713	Function	Transcription coactivator activity	IDA	15367689
GO:0003723	Function	RNA binding	HDA	22658674
GO:0004842	Function	Ubiquitin-protein transferase activity	IDA	14765125, 20061386, 21532592
GO:0004842	Function	Ubiquitin-protein transferase activity	IMP	10888878
GO:0004842	Function	Ubiquitin-protein transferase activity	TAS	8563171, 8576257
GO:0005515	Function	Protein binding	IPI	9990509, 10888878, 15367689, 16118314, 16169070, 16709802, 17003263, 19340006, 19549727, 23707686, 24076655, 24446487, 27565346, 28514442, 32296183, 32814053
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	11278816, 17003263
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IDA	9990509, 11278816, 17003263
GO:0005829	Component	Cytosol	TAS
GO:0006355	Process	Regulation of transcription, DNA-templated	IDA	17003263
GO:0006355	Process	Regulation of transcription, DNA-templated	IMP	15367689
GO:0006464	Process	Cellular protein modification process	TAS	8576257
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IBA	21873635
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	TAS	8563171, 8672131
GO:0008283	Process	Cell population proliferation	IMP	18946090
GO:0016567	Process	Protein ubiquitination	IDA	9990509, 21532592
GO:0016567	Process	Protein ubiquitination	TAS
GO:0019899	Function	Enzyme binding	TAS	8563171
GO:0031398	Process	Positive regulation of protein ubiquitination	IGI	12628165
GO:0031625	Function	Ubiquitin protein ligase binding	IBA	21873635
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	11278816, 12628165, 21532592
GO:0044770	Process	Cell cycle phase transition	IMP	18946090
GO:0045893	Process	Positive regulation of transcription, DNA-templated	IEA
GO:0051443	Process	Positive regulation of ubiquitin-protein transferase activity	IGI	12628165
GO:0061631	Function	Ubiquitin conjugating enzyme activity	IBA	21873635
GO:0061631	Function	Ubiquitin conjugating enzyme activity	IDA	20061386
GO:0070979	Process	Protein K11-linked ubiquitination	IBA	21873635
GO:0070979	Process	Protein K11-linked ubiquitination	IDA	20061386
GO:0071383	Process	Cellular response to steroid hormone stimulus	IMP	15367689
GO:0071385	Process	Cellular response to glucocorticoid stimulus	IDA	17003263
GO:0097027	Function	Ubiquitin-protein transferase activator activity	IGI	12628165
GO:1903955	Process	Positive regulation of protein targeting to mitochondrion	HMP	24270810

Other IDs

• MIM: 603721
• HGNC: 12488
• e!Ensembl: ENSG00000185651

Protein

• UniProt ID: P68036
• Protein name: Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3)
• Protein function: Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with
• PDB: 1C4Z, 1FBV, 3SQV, 3SY2, 4Q5E, 4Q5H, 5HPT, 5TTE, 5UDH, 6CP2, 6DJW, 6DJX, 6N13, 6XXU, 7B5L, 7B5N, 7OIK, 7V8F, 8EAZ, 8EB0
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00179	UQ_con	6 → 144	Ubiquitin-conjugating enzyme	Domain

• Sequence:

  MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
  YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
  LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD

• Sequence length: 154

Pathways

KEGG:

Ubiquitin mediated proteolysis
Parkinson disease
Pathways of neurodegeneration - multiple diseases

Reactome:

Synthesis of active ubiquitin: roles of E1 and E2 enzymes
E3 ubiquitin ligases ubiquitinate target proteins
Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Alzheimer disease	Alzheimer`s Disease	rs63750215, rs28936379, rs63749851, rs63749884, rs28936380, rs63750048, rs63750579, rs63750264, rs63749964, rs63750671, rs281865161, rs63750066, rs63750399, rs63750734, rs63751039, rs63750973, rs63749810, rs63750643, rs193922916, rs63750306, rs63750590, rs63750526, rs63751235, rs661, rs63751037, rs63749885, rs63750231, rs63751229, rs63751272, rs63751223, rs63750391, rs63751163, rs281875357, rs63751141, rs63750082, rs121917807, rs63751399, rs63750265, rs63751144, rs63750886, rs63751068, rs121917808, rs63749891, rs63750083, rs63749824, rs63750577, rs267606983, rs63750218, rs63751287, rs63750900, rs145518263, rs63751475, rs63750450, rs63749805, rs63751278, rs63751106, rs63750004, rs63749806, rs63751024, rs63750248, rs63750779, rs63751139, rs63750219, rs63750298, rs63750687, rs63750851, rs1553268799, rs1561901881, rs1561905293, rs866101707, rs1566638673, rs63750009, rs1566656702, rs1566657804, rs1567885728, rs1568339995, rs1566630791, rs1555358260, rs63750964, rs1594998354, rs63751316	30805717
Arthritis	Systemic onset juvenile chronic arthritis	rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470	23603761
Autoimmune diseases	Autoimmune Diseases, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2	rs41285370, rs869025224	21383967, 30595370, 30595370
Inflammatory bowel disease	Inflammatory Bowel Diseases	rs137853579, rs137853580, rs121909601, rs149491038, rs368287711, rs387907326, rs587777338, rs758439420, rs139868987, rs750447828, rs368138379, rs1329427406, rs1264862631, rs1192830343, rs1373354533, rs1419560997, rs1591263883, rs1989014468	23128233, 28067908, 26192919
Psoriasis	Psoriasis	rs281875215, rs587777763, rs281875213, rs281875212	26974007
Rheumatoid arthritis	Rheumatoid Arthritis, Rheumatoid Arthritis, Systemic Juvenile	rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212	27193031, 23603761
Systemic lupus erythematosus	Systemic lupus erythematosus	rs77571059, rs10954213, rs2070197, rs72556554, rs3219018, rs121912990, rs1575496354, rs7574865, rs1307379746, rs758750492, rs1575497576

Unknown
Disease name	Disease term	dbSNP ID	References
Ankylosing spondylitis	Ankylosing spondylitis		26974007, 23749187
Cholangitis	Cholangitis, Sclerosing		26974007
Crohn disease	Crohn Disease	rs2066847, rs2066844, rs886052047, rs5743265, rs111608429, rs104895438	26974007, 28067908, 21102463, 26192919
Immune system diseases	Immune System Diseases		21383967
Lupus erythematosus	Lupus Erythematosus, Systemic		22476155, 19838193, 26502338, 23917156, 27399966, 27193031, 24091983, 22045845, 28714469, 23943494, 18204446
Oligoarticular arthritis	Oligoarticular Juvenile Idiopathic Arthritis		23603761
Pauciarticular chronic arthritis	Juvenile pauciarticular chronic arthritis		23603761
Seronegative polyarthritis	Polyarticular Juvenile Idiopathic Arthritis, Rheumatoid Factor Negative		23603761
Psoriasis vulgaris	Psoriasis vulgaris		26626624
Still disease	Juvenile-Onset Still Disease		23603761
Ulcerative colitis	Ulcerative Colitis		23511034, 26974007