TRAF5 (TNF receptor associated factor 5)

Gene

• Entrez ID: 7188
• Gene name: TNF receptor associated factor 5
• Gene symbol: TRAF5
• Synonyms: MGC:39780, RNF84
• Chromosome: 1
• Chromosome location: 1q32.3
• Summary: The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF protei

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs756183569	AGAG>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT553425	hsa-miR-8485	PAR-CLIP	21572407
MIRT553424	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT553423	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT553422	hsa-miR-603	PAR-CLIP	21572407
MIRT553421	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT553420	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT553419	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT553418	hsa-miR-567	PAR-CLIP	21572407
MIRT553417	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT553416	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT553415	hsa-miR-3941	PAR-CLIP	21572407
MIRT553414	hsa-miR-3924	PAR-CLIP	21572407
MIRT553413	hsa-miR-297	PAR-CLIP	21572407
MIRT553412	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT553411	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT465320	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT465319	hsa-miR-3614-5p	PAR-CLIP	23592263
MIRT465318	hsa-miR-6500-3p	PAR-CLIP	23592263
MIRT465317	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT465315	hsa-miR-4459	PAR-CLIP	23592263
MIRT465316	hsa-miR-4433a-3p	PAR-CLIP	23592263
MIRT731422	hsa-miR-26b-5p	Luciferase reporter assay	26872428
MIRT731422	hsa-miR-26b-5p	Luciferase reporter assay	26872428
MIRT737074	hsa-miR-23a-3p	Luciferase reporter assay, Western blotting, Immunohistochemistry (IHC), qRT-PCR	34249436
MIRT553425	hsa-miR-8485	PAR-CLIP	21572407
MIRT553424	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT553423	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT553422	hsa-miR-603	PAR-CLIP	21572407
MIRT553421	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT553420	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT553419	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT553418	hsa-miR-567	PAR-CLIP	21572407
MIRT553417	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT553416	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT553415	hsa-miR-3941	PAR-CLIP	21572407
MIRT553414	hsa-miR-3924	PAR-CLIP	21572407
MIRT553413	hsa-miR-297	PAR-CLIP	21572407
MIRT553412	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT553411	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT465320	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT465319	hsa-miR-3614-5p	PAR-CLIP	23592263
MIRT465318	hsa-miR-6500-3p	PAR-CLIP	23592263
MIRT465317	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT465315	hsa-miR-4459	PAR-CLIP	23592263
MIRT465316	hsa-miR-4433a-3p	PAR-CLIP	23592263
MIRT1451006	hsa-miR-1262	CLIP-seq
MIRT1451007	hsa-miR-153	CLIP-seq
MIRT1451008	hsa-miR-15a	CLIP-seq
MIRT1451009	hsa-miR-15b	CLIP-seq
MIRT1451010	hsa-miR-16	CLIP-seq
MIRT1451011	hsa-miR-181a	CLIP-seq
MIRT1451012	hsa-miR-181b	CLIP-seq
MIRT1451013	hsa-miR-181c	CLIP-seq
MIRT1451014	hsa-miR-181d	CLIP-seq
MIRT1451015	hsa-miR-195	CLIP-seq
MIRT1451016	hsa-miR-3145-5p	CLIP-seq
MIRT1451017	hsa-miR-3149	CLIP-seq
MIRT1451018	hsa-miR-329	CLIP-seq
MIRT1451019	hsa-miR-365	CLIP-seq
MIRT1451020	hsa-miR-410	CLIP-seq
MIRT1451021	hsa-miR-424	CLIP-seq
MIRT1451022	hsa-miR-4252	CLIP-seq
MIRT1451023	hsa-miR-4262	CLIP-seq
MIRT1451024	hsa-miR-4457	CLIP-seq
MIRT1451025	hsa-miR-448	CLIP-seq
MIRT1451026	hsa-miR-4504	CLIP-seq
MIRT1451027	hsa-miR-452	CLIP-seq
MIRT1451028	hsa-miR-4524	CLIP-seq
MIRT1451029	hsa-miR-4641	CLIP-seq
MIRT1451030	hsa-miR-4676-3p	CLIP-seq
MIRT1451031	hsa-miR-4701-3p	CLIP-seq
MIRT1451032	hsa-miR-4789-5p	CLIP-seq
MIRT1451033	hsa-miR-4795-5p	CLIP-seq
MIRT1451034	hsa-miR-494	CLIP-seq
MIRT1451035	hsa-miR-497	CLIP-seq
MIRT1451036	hsa-miR-499-3p	CLIP-seq
MIRT1451037	hsa-miR-499a-3p	CLIP-seq
MIRT1451038	hsa-miR-503	CLIP-seq
MIRT1451039	hsa-miR-508-5p	CLIP-seq
MIRT1451040	hsa-miR-513b	CLIP-seq
MIRT1451041	hsa-miR-520d-5p	CLIP-seq
MIRT1451042	hsa-miR-524-5p	CLIP-seq
MIRT1451043	hsa-miR-568	CLIP-seq
MIRT1451044	hsa-miR-646	CLIP-seq
MIRT1451045	hsa-miR-661	CLIP-seq
MIRT1451046	hsa-miR-766	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT1451048	hsa-miR-3120-5p	CLIP-seq
MIRT1451049	hsa-miR-34b	CLIP-seq
MIRT1451050	hsa-miR-3613-3p	CLIP-seq
MIRT1451051	hsa-miR-3664-3p	CLIP-seq
MIRT1451052	hsa-miR-3664-5p	CLIP-seq
MIRT1451053	hsa-miR-371-5p	CLIP-seq
MIRT1451054	hsa-miR-371b-5p	CLIP-seq
MIRT1451055	hsa-miR-3929	CLIP-seq
MIRT1451056	hsa-miR-4419b	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT1451058	hsa-miR-4452	CLIP-seq
MIRT1451059	hsa-miR-4478	CLIP-seq
MIRT1451026	hsa-miR-4504	CLIP-seq
MIRT1451060	hsa-miR-4649-3p	CLIP-seq
MIRT1451061	hsa-miR-4695-5p	CLIP-seq
MIRT1451062	hsa-miR-4722-5p	CLIP-seq
MIRT1451063	hsa-miR-4738-3p	CLIP-seq
MIRT1451033	hsa-miR-4795-5p	CLIP-seq
MIRT1451064	hsa-miR-485-5p	CLIP-seq
MIRT1451065	hsa-miR-501-3p	CLIP-seq
MIRT1451066	hsa-miR-502-3p	CLIP-seq
MIRT1451067	hsa-miR-510	CLIP-seq
MIRT1451068	hsa-miR-512-5p	CLIP-seq
MIRT1451069	hsa-miR-563	CLIP-seq
MIRT1451070	hsa-miR-659	CLIP-seq
MIRT1451071	hsa-miR-940	CLIP-seq
MIRT1451007	hsa-miR-153	CLIP-seq
MIRT1451008	hsa-miR-15a	CLIP-seq
MIRT1451009	hsa-miR-15b	CLIP-seq
MIRT1451010	hsa-miR-16	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT1451015	hsa-miR-195	CLIP-seq
MIRT1451072	hsa-miR-29a	CLIP-seq
MIRT1451073	hsa-miR-29b	CLIP-seq
MIRT1451074	hsa-miR-29c	CLIP-seq
MIRT1451075	hsa-miR-3119	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT1451077	hsa-miR-3140-3p	CLIP-seq
MIRT1451078	hsa-miR-3160-3p	CLIP-seq
MIRT1451079	hsa-miR-3166	CLIP-seq
MIRT1451080	hsa-miR-3678-3p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT1451021	hsa-miR-424	CLIP-seq
MIRT1451084	hsa-miR-4311	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT1451025	hsa-miR-448	CLIP-seq
MIRT1451085	hsa-miR-4487	CLIP-seq
MIRT1451086	hsa-miR-450b-5p	CLIP-seq
MIRT1451028	hsa-miR-4524	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451088	hsa-miR-4753-5p	CLIP-seq
MIRT1451089	hsa-miR-4771	CLIP-seq
MIRT1451033	hsa-miR-4795-5p	CLIP-seq
MIRT1451035	hsa-miR-497	CLIP-seq
MIRT1451090	hsa-miR-499a-5p	CLIP-seq
MIRT1451038	hsa-miR-503	CLIP-seq
MIRT1451091	hsa-miR-507	CLIP-seq
MIRT1451041	hsa-miR-520d-5p	CLIP-seq
MIRT1451042	hsa-miR-524-5p	CLIP-seq
MIRT1451092	hsa-miR-557	CLIP-seq
MIRT1451093	hsa-miR-558	CLIP-seq
MIRT1451094	hsa-miR-601	CLIP-seq
MIRT1451044	hsa-miR-646	CLIP-seq
MIRT1555184	hsa-miR-4797-5p	CLIP-seq
MIRT2134812	hsa-miR-1226	CLIP-seq
MIRT1451011	hsa-miR-181a	CLIP-seq
MIRT1451012	hsa-miR-181b	CLIP-seq
MIRT1451013	hsa-miR-181c	CLIP-seq
MIRT1451014	hsa-miR-181d	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2134815	hsa-miR-218	CLIP-seq
MIRT2134816	hsa-miR-3148	CLIP-seq
MIRT2134817	hsa-miR-3660	CLIP-seq
MIRT2134818	hsa-miR-3682-5p	CLIP-seq
MIRT2134819	hsa-miR-382	CLIP-seq
MIRT2134820	hsa-miR-4256	CLIP-seq
MIRT1451023	hsa-miR-4262	CLIP-seq
MIRT2134821	hsa-miR-4279	CLIP-seq
MIRT2134822	hsa-miR-4328	CLIP-seq
MIRT2134823	hsa-miR-4477b	CLIP-seq
MIRT2134824	hsa-miR-4496	CLIP-seq
MIRT2134825	hsa-miR-4517	CLIP-seq
MIRT2134826	hsa-miR-4526	CLIP-seq
MIRT2134827	hsa-miR-4693-3p	CLIP-seq
MIRT2134828	hsa-miR-4693-5p	CLIP-seq
MIRT2134829	hsa-miR-4733-3p	CLIP-seq
MIRT2134830	hsa-miR-4799-5p	CLIP-seq
MIRT2134831	hsa-miR-491-3p	CLIP-seq
MIRT1451041	hsa-miR-520d-5p	CLIP-seq
MIRT1451042	hsa-miR-524-5p	CLIP-seq
MIRT2134832	hsa-miR-548an	CLIP-seq
MIRT2134833	hsa-miR-548g	CLIP-seq
MIRT2134834	hsa-miR-548m	CLIP-seq
MIRT2134835	hsa-miR-556-3p	CLIP-seq
MIRT2134836	hsa-miR-605	CLIP-seq
MIRT2134837	hsa-miR-636	CLIP-seq
MIRT2134838	hsa-miR-639	CLIP-seq
MIRT1451044	hsa-miR-646	CLIP-seq
MIRT2134839	hsa-miR-924	CLIP-seq
MIRT2356081	hsa-miR-1323	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2356082	hsa-miR-3065-3p	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT2356083	hsa-miR-3187-3p	CLIP-seq
MIRT1451049	hsa-miR-34b	CLIP-seq
MIRT2356084	hsa-miR-3612	CLIP-seq
MIRT1451051	hsa-miR-3664-3p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT2134819	hsa-miR-382	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2356085	hsa-miR-3926	CLIP-seq
MIRT1451055	hsa-miR-3929	CLIP-seq
MIRT2134821	hsa-miR-4279	CLIP-seq
MIRT1451056	hsa-miR-4419b	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT2356086	hsa-miR-4435	CLIP-seq
MIRT1451058	hsa-miR-4452	CLIP-seq
MIRT2356087	hsa-miR-4455	CLIP-seq
MIRT2356088	hsa-miR-4470	CLIP-seq
MIRT1451059	hsa-miR-4478	CLIP-seq
MIRT2134824	hsa-miR-4496	CLIP-seq
MIRT1451060	hsa-miR-4649-3p	CLIP-seq
MIRT2356089	hsa-miR-4684-5p	CLIP-seq
MIRT1451061	hsa-miR-4695-5p	CLIP-seq
MIRT2356090	hsa-miR-4701-5p	CLIP-seq
MIRT1451062	hsa-miR-4722-5p	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451064	hsa-miR-485-5p	CLIP-seq
MIRT1451067	hsa-miR-510	CLIP-seq
MIRT1451068	hsa-miR-512-5p	CLIP-seq
MIRT2356091	hsa-miR-548c-3p	CLIP-seq
MIRT2134834	hsa-miR-548m	CLIP-seq
MIRT2356092	hsa-miR-548o	CLIP-seq
MIRT2356093	hsa-miR-548s	CLIP-seq
MIRT2356094	hsa-miR-566	CLIP-seq
MIRT2356095	hsa-miR-588	CLIP-seq
MIRT2356096	hsa-miR-650	CLIP-seq
MIRT1451071	hsa-miR-940	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2134821	hsa-miR-4279	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT1451025	hsa-miR-448	CLIP-seq
MIRT2134824	hsa-miR-4496	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT2134834	hsa-miR-548m	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2356082	hsa-miR-3065-3p	CLIP-seq
MIRT1451048	hsa-miR-3120-5p	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT1451050	hsa-miR-3613-3p	CLIP-seq
MIRT1451052	hsa-miR-3664-5p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451053	hsa-miR-371-5p	CLIP-seq
MIRT1451054	hsa-miR-371b-5p	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2356089	hsa-miR-4684-5p	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451063	hsa-miR-4738-3p	CLIP-seq
MIRT2356091	hsa-miR-548c-3p	CLIP-seq
MIRT2462275	hsa-miR-619	CLIP-seq
MIRT2649595	hsa-miR-1256	CLIP-seq
MIRT2356081	hsa-miR-1323	CLIP-seq
MIRT1451007	hsa-miR-153	CLIP-seq
MIRT1451008	hsa-miR-15a	CLIP-seq
MIRT1451009	hsa-miR-15b	CLIP-seq
MIRT1451010	hsa-miR-16	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT1451015	hsa-miR-195	CLIP-seq
MIRT2649596	hsa-miR-2053	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2134815	hsa-miR-218	CLIP-seq
MIRT2649597	hsa-miR-24	CLIP-seq
MIRT2649598	hsa-miR-298	CLIP-seq
MIRT2356082	hsa-miR-3065-3p	CLIP-seq
MIRT1451048	hsa-miR-3120-5p	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT2134816	hsa-miR-3148	CLIP-seq
MIRT2649599	hsa-miR-3154	CLIP-seq
MIRT2356083	hsa-miR-3187-3p	CLIP-seq
MIRT1451050	hsa-miR-3613-3p	CLIP-seq
MIRT1451019	hsa-miR-365	CLIP-seq
MIRT1451051	hsa-miR-3664-3p	CLIP-seq
MIRT1451052	hsa-miR-3664-5p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451053	hsa-miR-371-5p	CLIP-seq
MIRT1451054	hsa-miR-371b-5p	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2356085	hsa-miR-3926	CLIP-seq
MIRT1451055	hsa-miR-3929	CLIP-seq
MIRT1451020	hsa-miR-410	CLIP-seq
MIRT1451021	hsa-miR-424	CLIP-seq
MIRT1451056	hsa-miR-4419b	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT2356086	hsa-miR-4435	CLIP-seq
MIRT2649600	hsa-miR-4436a	CLIP-seq
MIRT2649601	hsa-miR-4437	CLIP-seq
MIRT2649602	hsa-miR-4453	CLIP-seq
MIRT1451024	hsa-miR-4457	CLIP-seq
MIRT2356088	hsa-miR-4470	CLIP-seq
MIRT2134823	hsa-miR-4477b	CLIP-seq
MIRT1451059	hsa-miR-4478	CLIP-seq
MIRT1451025	hsa-miR-448	CLIP-seq
MIRT2134825	hsa-miR-4517	CLIP-seq
MIRT1451028	hsa-miR-4524	CLIP-seq
MIRT2649603	hsa-miR-4538	CLIP-seq
MIRT1451029	hsa-miR-4641	CLIP-seq
MIRT2649604	hsa-miR-4642	CLIP-seq
MIRT1451060	hsa-miR-4649-3p	CLIP-seq
MIRT2356089	hsa-miR-4684-5p	CLIP-seq
MIRT1451061	hsa-miR-4695-5p	CLIP-seq
MIRT2356090	hsa-miR-4701-5p	CLIP-seq
MIRT1451062	hsa-miR-4722-5p	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451063	hsa-miR-4738-3p	CLIP-seq
MIRT2134830	hsa-miR-4799-5p	CLIP-seq
MIRT1451064	hsa-miR-485-5p	CLIP-seq
MIRT1451034	hsa-miR-494	CLIP-seq
MIRT1451035	hsa-miR-497	CLIP-seq
MIRT1451036	hsa-miR-499-3p	CLIP-seq
MIRT1451037	hsa-miR-499a-3p	CLIP-seq
MIRT1451038	hsa-miR-503	CLIP-seq
MIRT1451067	hsa-miR-510	CLIP-seq
MIRT1451068	hsa-miR-512-5p	CLIP-seq
MIRT1451040	hsa-miR-513b	CLIP-seq
MIRT1451041	hsa-miR-520d-5p	CLIP-seq
MIRT1451042	hsa-miR-524-5p	CLIP-seq
MIRT2134832	hsa-miR-548an	CLIP-seq
MIRT2356091	hsa-miR-548c-3p	CLIP-seq
MIRT2356092	hsa-miR-548o	CLIP-seq
MIRT2356093	hsa-miR-548s	CLIP-seq
MIRT2649605	hsa-miR-549	CLIP-seq
MIRT2356094	hsa-miR-566	CLIP-seq
MIRT2356095	hsa-miR-588	CLIP-seq
MIRT2134836	hsa-miR-605	CLIP-seq
MIRT2649606	hsa-miR-617	CLIP-seq
MIRT2462275	hsa-miR-619	CLIP-seq
MIRT2649607	hsa-miR-627	CLIP-seq
MIRT2134837	hsa-miR-636	CLIP-seq
MIRT1451044	hsa-miR-646	CLIP-seq
MIRT2134839	hsa-miR-924	CLIP-seq
MIRT1451071	hsa-miR-940	CLIP-seq
MIRT2356081	hsa-miR-1323	CLIP-seq
MIRT2356092	hsa-miR-548o	CLIP-seq
MIRT2356081	hsa-miR-1323	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2356082	hsa-miR-3065-3p	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT2356083	hsa-miR-3187-3p	CLIP-seq
MIRT1451049	hsa-miR-34b	CLIP-seq
MIRT1451051	hsa-miR-3664-3p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2356085	hsa-miR-3926	CLIP-seq
MIRT1451055	hsa-miR-3929	CLIP-seq
MIRT1451056	hsa-miR-4419b	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT2356086	hsa-miR-4435	CLIP-seq
MIRT2649602	hsa-miR-4453	CLIP-seq
MIRT2356088	hsa-miR-4470	CLIP-seq
MIRT1451059	hsa-miR-4478	CLIP-seq
MIRT2649603	hsa-miR-4538	CLIP-seq
MIRT1451060	hsa-miR-4649-3p	CLIP-seq
MIRT2356089	hsa-miR-4684-5p	CLIP-seq
MIRT1451061	hsa-miR-4695-5p	CLIP-seq
MIRT2356090	hsa-miR-4701-5p	CLIP-seq
MIRT1451062	hsa-miR-4722-5p	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451064	hsa-miR-485-5p	CLIP-seq
MIRT1451067	hsa-miR-510	CLIP-seq
MIRT1451068	hsa-miR-512-5p	CLIP-seq
MIRT2356091	hsa-miR-548c-3p	CLIP-seq
MIRT2356092	hsa-miR-548o	CLIP-seq
MIRT2356093	hsa-miR-548s	CLIP-seq
MIRT2356094	hsa-miR-566	CLIP-seq
MIRT2356095	hsa-miR-588	CLIP-seq
MIRT2462275	hsa-miR-619	CLIP-seq
MIRT1451071	hsa-miR-940	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004842	Function	Ubiquitin-protein transferase activity	IBA	21873635
GO:0005164	Function	Tumor necrosis factor receptor binding	IBA	21873635
GO:0005515	Function	Protein binding	IPI	9153189, 9162022, 15121867, 21516116, 21822258, 22493164, 25241761, 25416956, 27107012, 28514442, 32296183, 32814053
GO:0005813	Component	Centrosome	IDA	21399614
GO:0005829	Component	Cytosol	IDA	15121867
GO:0006915	Process	Apoptotic process	IEA
GO:0007165	Process	Signal transduction	TAS	9511754
GO:0008270	Function	Zinc ion binding	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0009898	Component	Cytoplasmic side of plasma membrane	IBA	21873635
GO:0009898	Component	Cytoplasmic side of plasma membrane	ISS
GO:0031625	Function	Ubiquitin protein ligase binding	IBA	21873635
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	11279055
GO:0031996	Function	Thioesterase binding	IBA	21873635
GO:0031996	Function	Thioesterase binding	IPI	11279055
GO:0033209	Process	Tumor necrosis factor-mediated signaling pathway	IBA	21873635
GO:0035631	Component	CD40 receptor complex	ISS
GO:0042802	Function	Identical protein binding	IPI	22493164, 25416956, 32296183
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0043122	Process	Regulation of I-kappaB kinase/NF-kappaB signaling	IBA	21873635
GO:0043123	Process	Positive regulation of I-kappaB kinase/NF-kappaB signaling	IEP	12761501
GO:0046330	Process	Positive regulation of JNK cascade	IBA	21873635
GO:0051091	Process	Positive regulation of DNA-binding transcription factor activity	IMP	12296995
GO:0051092	Process	Positive regulation of NF-kappaB transcription factor activity	IMP	12296995, 15121867
GO:0070534	Process	Protein K63-linked ubiquitination	IBA	21873635
GO:0098802	Component	Plasma membrane signaling receptor complex	IBA	21873635

Other IDs

• MIM: 602356
• HGNC: 12035
• e!Ensembl: ENSG00000082512

Protein

• UniProt ID: O00463
• Protein name: TNF receptor-associated factor 5 (RING finger protein 84)
• Protein function: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably
• PDB: 7L3L
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00097	zf-C3HC4	45 → 83	Zinc finger, C3HC4 type (RING finger)	Domain
  PF02176	zf-TRAF	128 → 183	TRAF-type zinc finger	Family
  PF02176	zf-TRAF	183 → 241	TRAF-type zinc finger	Family

• Sequence:

  MAYSEEHKGMPCGFIRQNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGC
  GHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKV
  ILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINL
  QNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQ
  HEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFG
  KNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLE
  NNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREA
  VDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQ
  RVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKD
  DTLFLKVAVDLTDLEDL

• Sequence length: 557

Pathways

KEGG:

NF-kappa B signaling pathway
Necroptosis
NOD-like receptor signaling pathway
IL-17 signaling pathway
TNF signaling pathway
Shigellosis
Human cytomegalovirus infection
Herpes simplex virus 1 infection
Epstein-Barr virus infection
Human immunodeficiency virus 1 infection
Pathways in cancer
Viral carcinogenesis
Small cell lung cancer

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Diffuse lymphoma	Diffuse Large B-Cell Lymphoma	rs121912651, rs121913289, rs121913293, rs878854402, rs869025340, rs1349928568, rs1569115687, rs121913291
Glioma	Glioma	rs121909219, rs121909224, rs587776667, rs587776671, rs121909239, rs121909241, rs28933368, rs121913500, rs55863639, rs786201995, rs786202517, rs786201044, rs398123317, rs1057518425, rs121913499, rs1060500122, rs781647403, rs1060500126, rs1554897889, rs1114167629, rs1114167656, rs587782603, rs1554893824, rs1554900615, rs1564568660, rs786204900, rs762518389, rs1339631701	19578366

Unknown
Disease name	Disease term	dbSNP ID	References
Central nervous system neoplasms	Central Nervous System Neoplasms		19578366